LOCUS       NP_080104                358 aa            linear   ROD 02-JUN-2024
DEFINITION  vesicular integral-membrane protein VIP36 precursor [Mus musculus].
ACCESSION   NP_080104
VERSION     NP_080104.2
DBSOURCE    REFSEQ: accession NM_025828.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (residues 1 to 358)
  AUTHORS   Shirakabe,K., Hattori,S., Seiki,M., Koyasu,S. and Okada,Y.
  TITLE     VIP36 protein is a target of ectodomain shedding and regulates
            phagocytosis in macrophage Raw 264.7 cells
  JOURNAL   J Biol Chem 286 (50), 43154-43163 (2011)
   PUBMED   22016386
  REMARK    Erratum:[J Biol Chem. 2012 Jun 1;287(23):19340]
REFERENCE   2  (residues 1 to 358)
  AUTHORS   Lau,N.C., Seto,A.G., Kim,J., Kuramochi-Miyagawa,S., Nakano,T.,
            Bartel,D.P. and Kingston,R.E.
  TITLE     Characterization of the piRNA complex from rat testes
  JOURNAL   Science 313 (5785), 363-367 (2006)
   PUBMED   16778019
REFERENCE   3  (residues 1 to 358)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   4  (residues 1 to 358)
  AUTHORS   Piao,Y., Ko,N.T., Lim,M.K. and Ko,M.S.
  TITLE     Construction of long-transcript enriched cDNA libraries from
            submicrogram amounts of total RNAs by a universal PCR amplification
            method
  JOURNAL   Genome Res 11 (9), 1553-1558 (2001)
   PUBMED   11544199
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CT009762.8 and
            AC160958.2.
            
            On Aug 28, 2003 this sequence version replaced NP_080104.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC055327.1, AK129028.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849380, SAMN00849381
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..358
                     /organism="Mus musculus"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 29.8 cM"
     Protein         1..358
                     /product="vesicular integral-membrane protein VIP36
                     precursor"
                     /note="vesicular integral-membrane protein VIP36;
                     vesicular integral-membrane protein 36"
                     /calculated_mol_wt=35469
     sig_peptide     1..46
                     /inference="COORDINATES: ab initio prediction:SignalP:6.0"
                     /calculated_mol_wt=4979
     mat_peptide     47..358
                     /product="Vesicular integral-membrane protein VIP36.
                     /id=PRO_0000017667"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9DBH5.2)"
                     /calculated_mol_wt=35469
     Region          55..303
                     /region_name="lectin_VIP36_VIPL"
                     /note="VIP36 and VIPL type 1 transmembrane proteins,
                     lectin domain; cd06901"
                     /db_xref="CDD:173889"
     Site            order(133,166,168,192,262..264)
                     /site_type="other"
                     /note="carbohydrate binding site [chemical binding]"
                     /db_xref="CDD:173889"
     Site            order(164,168,192,195)
                     /site_type="metal-binding"
                     /note="metal binding site [ion binding]"
                     /db_xref="CDD:173889"
     Site            185
                     /site_type="glycosylation"
                     /note="N-linked (GlcNAc...) asparagine.
                     /evidence=ECO:0000255; propagated from
                     UniProtKB/Swiss-Prot (Q9DBH5.2)"
     Site            325..347
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9DBH5.2)"
     CDS             1..358
                     /gene="Lman2"
                     /gene_synonym="1110003H06Rik; 1300009F09Rik; GP36B; VIP36"
                     /coded_by="NM_025828.3:195..1271"
                     /db_xref="CCDS:CCDS26544.1"
                     /db_xref="GeneID:66890"
                     /db_xref="MGI:MGI:1914140"
ORIGIN      
        1 maaeawlwrw gwgwgqrcpg rpglpgpgps pttflhllll lgpvaaditd gnsehlkreh
       61 slikpyqgvg sssmplwdfq gstmltsqyv rltpderske gsiwnhqpcf lkdwemhvhf
      121 kvhgtgkknl hgdgialwyt rdrlvpgpvf gskdnfhgla ifldtypnde ttervfpyis
      181 vmvnngslsy dhskdgrwse lagctadfrn rdhdtflavr ysrgrltvmt dledknewkn
      241 ciditgvrlp tgyyfgasag tgdlsdnhdi isiklfqltv ertpeeesid wtkiepgvnf
      301 lkspkdnvdd ptgnfrngpl tgwrvfllll callgvvvca vvgavvfqkr qernkrfy
//
