LOCUS       NM_001163170            2509 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus Lix1-like (Lix1l), mRNA.
ACCESSION   NM_001163170
VERSION     NM_001163170.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2509)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2509)
  AUTHORS   Moore,K.S., Moore,R., Fulmer,D.B., Guo,L., Gensemer,C.,
            Stairley,R., Glover,J., Beck,T.C., Morningstar,J.E., Biggs,R.,
            Muhkerjee,R., Awgulewitsch,A. and Norris,R.A.
  TITLE     DCHS1, Lix1L, and the Septin Cytoskeleton: Molecular and
            Developmental Etiology of Mitral Valve Prolapse
  JOURNAL   J Cardiovasc Dev Dis 9 (2), 62 (2022)
   PUBMED   35200715
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2509)
  AUTHORS   Zhu,X., Zhang,Y., Zhao,Y., Xiang,D., Zou,J., Andrisani,O., Zhang,H.
            and Kong,L.
  TITLE     LIX1-like protein drives hepatic stellate cell activation to
            promote liver fibrosis by regulation of chemokine mRNA stability
  JOURNAL   Signal Transduct Target Ther 6 (1), 319 (2021)
   PUBMED   34465730
  REMARK    GeneRIF: LIX1-like protein drives hepatic stellate cell activation
            to promote liver fibrosis by regulation of chemokine mRNA
            stability.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 2509)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 2509)
  AUTHORS   Thiagarajan,R.D., Georgas,K.M., Rumballe,B.A., Lesieur,E.,
            Chiu,H.S., Taylor,D., Tang,D.T., Grimmond,S.M. and Little,M.H.
  TITLE     Identification of anchor genes during kidney development defines
            ontological relationships, molecular subcompartments and regulatory
            pathways
  JOURNAL   PLoS One 6 (2), e17286 (2011)
   PUBMED   21386911
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 2509)
  AUTHORS   Combes,A.N., Lesieur,E., Harley,V.R., Sinclair,A.H., Little,M.H.,
            Wilhelm,D. and Koopman,P.
  TITLE     Three-dimensional visualization of testis cord morphogenesis, a
            novel tubulogenic mechanism in development
  JOURNAL   Dev Dyn 238 (5), 1033-1041 (2009)
   PUBMED   19334288
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK143438.1 and AK051276.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK143438.1, SRR1660821.191997.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-190               AK143438.1         2-191
            191-206             AK051276.1         176-191
            207-475             AK143438.1         208-476
            476-1143            AK051276.1         461-1128
            1144-2509           AK143438.1         1153-2518
FEATURES             Location/Qualifiers
     source          1..2509
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 41.93 cM"
     gene            1..2509
                     /gene="Lix1l"
                     /gene_synonym="D130027M04Rik"
                     /note="Lix1-like"
                     /db_xref="GeneID:280411"
                     /db_xref="MGI:MGI:3036267"
     exon            1..341
                     /gene="Lix1l"
                     /gene_synonym="D130027M04Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             50..1063
                     /gene="Lix1l"
                     /gene_synonym="D130027M04Rik"
                     /codon_start=1
                     /product="LIX1-like protein"
                     /protein_id="NP_001156642.1"
                     /db_xref="CCDS:CCDS51004.1"
                     /db_xref="GeneID:280411"
                     /db_xref="MGI:MGI:3036267"
                     /translation="METMRAQRLQPGVGVGGRGTLRALRPGVTGAPTSAATPPVGPPP
                     APPPPAPPPPPLLLAGAPGLPLPPGAAGSPAVLREAVEAVVRSFAKHTQGYGRVNVVE
                     ALQEFWQMKQSRGADLKNGALVVYEMVPSNSPPYVCYVTLPGGSCFGSFQFCPTKAEA
                     RRSAAKIALMNSVFNEHPSRRITDEFIEKSVSEALASFNGNREEADNPNTGIGAFRFM
                     LESNKGKSMLEFQELMTVFQLLHWNGSLKAMRERQCSRQEVLAHYSHRALDDDIRHQM
                     ALDWVSREQSVPGALSRELASTERELDEARLAGKELRFHKEKKDILMLAAGQLGNMHS
                     SSC"
     exon            342..505
                     /gene="Lix1l"
                     /gene_synonym="D130027M04Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            506..646
                     /gene="Lix1l"
                     /gene_synonym="D130027M04Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            647..742
                     /gene="Lix1l"
                     /gene_synonym="D130027M04Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            743..820
                     /gene="Lix1l"
                     /gene_synonym="D130027M04Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            821..2509
                     /gene="Lix1l"
                     /gene_synonym="D130027M04Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1173..1178
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Lix1l"
                     /gene_synonym="D130027M04Rik"
                     /note="hexamer: AATATA"
     regulatory      1189..1194
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Lix1l"
                     /gene_synonym="D130027M04Rik"
                     /note="hexamer: TATAAA"
     polyA_site      1199
                     /gene="Lix1l"
                     /gene_synonym="D130027M04Rik"
                     /note="major polyA site"
     polyA_site      1213
                     /gene="Lix1l"
                     /gene_synonym="D130027M04Rik"
     polyA_site      1243
                     /gene="Lix1l"
                     /gene_synonym="D130027M04Rik"
     polyA_site      1286
                     /gene="Lix1l"
                     /gene_synonym="D130027M04Rik"
     polyA_site      1347
                     /gene="Lix1l"
                     /gene_synonym="D130027M04Rik"
ORIGIN      
        1 agctcgccag gctggcaggc tccggggccc agctccgccg gccaccggga tggagacgat
       61 gcgagcacag cggctgcagc ccggtgtagg cgtcggtggg agaggcactt tgcgagcgct
      121 gcggccaggg gtgaccgggg ccccgactag cgccgccaca ccccccgtgg gcccgccgcc
      181 cgccccgccg ccccccgccc cgcccccgcc tccgctgctt ctggctgggg cccccgggct
      241 gcccctgccc cccggcgccg cgggtagccc tgcggtgctg cgcgaggctg tggaggcggt
      301 ggtgaggagc ttcgccaagc acacgcaggg ctacggtcga gtgaatgtgg tggaggccct
      361 tcaggaattc tggcagatga aacagtctcg gggcgctgac ttgaagaacg gggctctggt
      421 ggtgtacgag atggtcccct ccaacagccc tccctacgtc tgctatgtca ctctgcctgg
      481 ggggagctgc ttcgggagtt tccagttttg tcccacaaaa gctgaggccc ggcgaagtgc
      541 tgcaaagatt gcattaatga actctgtgtt taatgagcat ccatcccgaa gaattactga
      601 tgagtttatt gagaagagtg tctcagaggc cctggcatct ttcaatggta acagagagga
      661 agctgacaac ccaaatacgg ggattggtgc cttccgattc atgttggaat ctaacaaggg
      721 caagtcaatg ctggagttcc aggagctgat gacagttttt cagctgctgc actggaatgg
      781 cagccttaag gccatgaggg aaagacagtg ctctcgacag gaggtgttgg ctcattattc
      841 acatcgggcc ctggatgatg atattcgcca ccaaatggct ttggactggg tgagccggga
      901 gcagagtgtg ccaggggcac tgtcaagaga gctggcttcc actgaacggg aactcgatga
      961 agcccggctg gcgggcaagg agctgcgctt ccacaaggag aagaaagata ttctcatgct
     1021 ggctgctggg cagttgggca atatgcattc ttccagctgc taagcatcta ccctctactc
     1081 gccatggctc ttcaggcccc ttttttgtat gtctcctttt taagacttag gatgatgatt
     1141 tctgtatata ctttctcaat tttatacttt aaaatataga tatatatgta taaattctac
     1201 acctggctcc ctatttgcta agagatccct tttctaactt ccagtttggg gatgtagtta
     1261 cctttgaaat atcactatcc attttatagc gtggttggct cttaaacctt tagattatct
     1321 aagtcattaa catgtacagt tttctaagtg ttcatatctc tttcttttga aacagcagca
     1381 cacaggtacg tgatgactca gctatgctct ctgcactcag cagtctgaga cagtattgct
     1441 gtgaatatga ggccagcctg gactacataa taagttccag gtcagcatgg gctacagtgt
     1501 gtaagatcct gtttcagacc cctctctccc acacataaaa ccgcccatat tcttggtttc
     1561 tactagacga aaacagggtg ggagcgtcag gttttggttt gaagtgaccg tccgatccac
     1621 ctcccctgct cactttcctc cttccttgcc tctaagtgct ccttcatttg ggggcttccc
     1681 taccttatcc agaagatctg gcttcctttt gttttgtgag acatcttatt atggcctgga
     1741 actcatccta tagattagga gggcttcatg cttgtggttg tatcctgctg aaatcatagg
     1801 catgggtcac aatgagaaac tgcctaggaa caagagaatg atacactcaa ttcacatggg
     1861 gtgggtaggt ggcactacct gagctgcttc tgagcttacc tacccctgct agcagtctag
     1921 ctttctgggt gtgagaagag ggtaagggtt gaggctgata ctggtacacg cacatgtgag
     1981 cacacacttt tttccatttg ttcatgtagc ccaggctggt ctcaaactct tcttctggct
     2041 gagaatggcc ctgagctcca gacctcccgc atcagcctct ccctaggatt acagtgacta
     2101 ccaccgcagc tgccttaatc ctcccctcag tgacaagaag catcttgttc tttagaaacg
     2161 gtagctgttc tgtttagaga gaaccatgtt cctctcttgt ccactgagct gtaactctga
     2221 atttgtggag aattctatgt agtaagctca atttcccttc tttctgtggt ctctgctaca
     2281 ttgtattatt gttcagtgca ctttctatca agttgggaca gttaatgcta ctataatgcg
     2341 acttcccatg tgacaattgc agtttgattt taggttagga gctgggtctg gtggtgcagg
     2401 tctgccatct cagctacaaa ggaggccaag gcaagattgg aaattcaagg tctaccccag
     2461 ctagagcaag ttcaggggca acctgggtaa tttagcaaga ctctatctc
//
