LOCUS       NM_023903               2701 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus lipase, family member M (Lipm), mRNA.
ACCESSION   NM_023903
VERSION     NM_023903.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2701)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK037091.1 and AK085719.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK085719.1, AK037214.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849387, SAMN01164137
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2047              AK037091.1         3-2049
            2048-2701           AK085719.1         2024-2677
FEATURES             Location/Qualifiers
     source          1..2701
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="19"
                     /map="19 29.32 cM"
     gene            1..2701
                     /gene="Lipm"
                     /gene_synonym="4632427C23Rik; Lipl3"
                     /note="lipase, family member M"
                     /db_xref="GeneID:78753"
                     /db_xref="MGI:MGI:1926003"
     exon            1..74
                     /gene="Lipm"
                     /gene_synonym="4632427C23Rik; Lipl3"
                     /inference="alignment:Splign:2.1.0"
     exon            75..288
                     /gene="Lipm"
                     /gene_synonym="4632427C23Rik; Lipl3"
                     /inference="alignment:Splign:2.1.0"
     CDS             142..1410
                     /gene="Lipm"
                     /gene_synonym="4632427C23Rik; Lipl3"
                     /note="lipase-like, ab-hydrolase domain containing 3;
                     lipase member M; lipase-like abhydrolase domain-containing
                     protein 3"
                     /codon_start=1
                     /product="lipase member M precursor"
                     /protein_id="NP_076392.1"
                     /db_xref="CCDS:CCDS50419.1"
                     /db_xref="GeneID:78753"
                     /db_xref="MGI:MGI:1926003"
                     /translation="MSEILSRVWTVSHRVEIWLLILVAYLLQRNVNSGHLPTKAADPE
                     AFMNVSEIIKHKGYPSEEYEVATEDGYILSVNRIPRGQTRLKKEGSRPVVLLQHGLLG
                     DASNWISNLPNNSLGFILADAGFDVWMGNSRGNTWSRKHKTLSIDQDEFWAFSYDEMA
                     RFDLPAVINFILQKTGQKKVYYVGYSQGTTMGFIAFSTMPELAHKIKMYFALAPIATV
                     KYARSPGTKFLLLPDMMIKVLFGRQEFLYQTRFFRQLFIYLCGQMILDQICSNIILLL
                     GGFNTNNMNMSRANVYVAHTPAGTSVQNILHWSQAVNSGELRAFDWGSETKNQEKCNQ
                     PTPIRYKVRDMMVPTAMWTGGQDWLSNPDDVKTLLSEVTNLIYHKNIPEWAHVDFIWG
                     LDAPQRVYNEIIHLMKQEPNLPQGTCRVKL"
     exon            289..406
                     /gene="Lipm"
                     /gene_synonym="4632427C23Rik; Lipl3"
                     /inference="alignment:Splign:2.1.0"
     exon            407..605
                     /gene="Lipm"
                     /gene_synonym="4632427C23Rik; Lipl3"
                     /inference="alignment:Splign:2.1.0"
     exon            606..715
                     /gene="Lipm"
                     /gene_synonym="4632427C23Rik; Lipl3"
                     /inference="alignment:Splign:2.1.0"
     exon            716..852
                     /gene="Lipm"
                     /gene_synonym="4632427C23Rik; Lipl3"
                     /inference="alignment:Splign:2.1.0"
     exon            853..999
                     /gene="Lipm"
                     /gene_synonym="4632427C23Rik; Lipl3"
                     /inference="alignment:Splign:2.1.0"
     exon            1000..1071
                     /gene="Lipm"
                     /gene_synonym="4632427C23Rik; Lipl3"
                     /inference="alignment:Splign:2.1.0"
     exon            1072..1143
                     /gene="Lipm"
                     /gene_synonym="4632427C23Rik; Lipl3"
                     /inference="alignment:Splign:2.1.0"
     exon            1144..2701
                     /gene="Lipm"
                     /gene_synonym="4632427C23Rik; Lipl3"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2025..2030
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Lipm"
                     /gene_synonym="4632427C23Rik; Lipl3"
                     /note="hexamer: AATAAA"
     polyA_site      2048
                     /gene="Lipm"
                     /gene_synonym="4632427C23Rik; Lipl3"
                     /note="major polyA site"
     regulatory      2552..2557
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Lipm"
                     /gene_synonym="4632427C23Rik; Lipl3"
                     /note="hexamer: TATAAA"
     polyA_site      2573
                     /gene="Lipm"
                     /gene_synonym="4632427C23Rik; Lipl3"
ORIGIN      
        1 ggagcaggag gagctaggca gcattgtgac attctaagca atgtttgcag cctacaccgt
       61 gttctttcat tcctgttctt cttctgactc tagatgtagt tgttacatcc ttagcaacaa
      121 agcaaatgcc gatgttggac catgtcagaa atcttgtcaa gagtgtggac tgtttcgcac
      181 agagtggaga tatggcttct gattctggta gcgtatttac tccaaagaaa tgtgaactcg
      241 ggacatttgc ccacgaaagc tgcggatcca gaagcattca tgaatgttag cgaaatcatc
      301 aaacacaagg gttatcccag tgaggagtat gaagttgcaa cggaagatgg gtacatcctt
      361 tctgtgaaca gaatccctcg gggacagaca cggttaaaga aggaaggatc caggccagtg
      421 gtgttactgc aacatggtct tcttggggat gctagcaact ggatttccaa cctgcccaac
      481 aacagcctgg gttttattct ggcagatgca ggttttgatg tgtggatggg aaacagcaga
      541 ggaaacacct ggtctcggaa gcacaagacc ctctccatag atcaagatga gttctgggct
      601 ttcagttatg atgaaatggc taggtttgac cttccagctg tgataaactt tatcttacag
      661 aaaacgggcc agaaaaaggt ctattatgtc ggctactcac agggcaccac catgggcttt
      721 attgcatttt ccacaatgcc agagctagct cataaaatca aaatgtattt tgccttagct
      781 cctatagcca ctgttaaata tgcaagaagt cctggtacca aatttctgct gctgccagat
      841 atgatgatca aggtattatt tggcagacaa gagtttttat accagactag atttttcaga
      901 cagcttttta tttacctttg tggccagatg attcttgacc aaatctgcag caacatcatc
      961 ttactcctgg gaggttttaa cacaaacaat atgaacatga gcagagcaaa tgtgtatgtc
     1021 gcccatacac ctgctggaac gtctgtgcag aacattctcc actggagcca ggccgtgaat
     1081 tctggggaac ttcgtgcctt tgactgggga agtgagacca aaaatcagga gaaatgtaat
     1141 cagccaactc ctataaggta caaagttcga gatatgatgg tcccaacagc aatgtggact
     1201 ggaggtcaag actggctttc aaatccagat gatgtgaaaa cattactttc tgaagtaacc
     1261 aacctcatct accacaagaa cattcctgag tgggctcatg tggatttcat ctgggggctg
     1321 gatgcccctc agcgtgttta caatgaaatt atacatctga tgaagcagga gcccaacctt
     1381 ccccagggaa cctgcagggt caaattgtga agctcctgca agtcttagaa caaccccatg
     1441 cggaatgggc agggccatgg gaggatggat gctcaaagaa atgtacagac ttggaaacct
     1501 gctatatcag ttagtcagaa ggacagagga gatacccaga tgccagaaga cctcctggtc
     1561 caaattaaag cttcatttgt ttcttcattt gacacgaaag ctgatactta cactttttcc
     1621 agttggttaa actcagttgg tgaacacagg ttttctgtgc tttctatctt tgtcatggtg
     1681 caatgtagtt tttacttacc cacaagatgt atctagactg ttatcattgc atcattcaac
     1741 ctttccaaca taatttttgt ttttgaaagt cgaattttta gagcattaaa agcaataatt
     1801 ggggcaggga tcaaaattgt aaatctttgg attgttgact tggataaaat gaagtggacc
     1861 ttgccatcac attgccataa agacaagaca cttctttaag aagccaggct atttggtcat
     1921 caactgaaaa ctgaaatcat tgtgggtagg tggagtctaa ctaaacaatc aagttttaaa
     1981 gttggatctc aaagcttatt ttgtaggata tttatgagtt ttccaataaa ttaattatgt
     2041 agctcccatg tcatgtctgt gtatcagtac taagattttc atctgctatt agaccagctg
     2101 ctccaaatga gtaaaatgaa ataaactgtt gtgtatttta tcctttaatc aatgccgaat
     2161 cactcttaga taatctccaa actcttgcat agatctagat ttatgtcctt ggaaaactct
     2221 ttaattttca cacaatttca aatatgacag tagtaaatta tgagtattat ttggcattct
     2281 actctgaaga caaataaaag ctctcctgtg cctgttggag ttccagttga gaatatacag
     2341 ttgtttgtta aacatacatt agactgtgaa gttctttttt tcccccagag ttgcctggta
     2401 agttagtcca atgttaccaa atcttaggta aattacttag taatatttag ggacttcagg
     2461 accccatgtg tacccttagg gtctatatat agcttagtat acatgtccag atttgatttt
     2521 tgttgaacct cttgtaaaaa atgactgtta ttataaatgt atcagtaaat taatacgtca
     2581 gttgttttta tttatcctac cttgttctcc aataatgtca cagacagacc aaaattagat
     2641 taccagagga taatgcctag ctattgtacg ttaagttgaa aataaatcac aaaggagtct
     2701 t
//
