LOCUS       NM_172837               2225 bp    mRNA    linear   ROD 03-JUN-2024
DEFINITION  Mus musculus lipase, family member K (Lipk), transcript variant 2,
            mRNA.
ACCESSION   NM_172837
VERSION     NM_172837.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2225)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY150606.1, AK037106.1 and AC102119.10.
            
            On Apr 16, 2011 this sequence version replaced NM_172837.3.
            
            Transcript Variant: This variant (2) uses an alternate in-frame
            splice site in the central coding region, compared to variant 1.
            This results in a shorter protein (isoform 2), compared to isoform
            1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK037106.1, AK162706.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381, SAMN00849387
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-36                BY150606.1         1-36
            37-2117             AK037106.1         2-2082
            2118-2225           AC102119.10        197095-197202
FEATURES             Location/Qualifiers
     source          1..2225
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="19"
                     /map="19 29.3 cM"
     gene            1..2225
                     /gene="Lipk"
                     /gene_synonym="9930115F20; Lipl2"
                     /note="lipase, family member K"
                     /db_xref="GeneID:240633"
                     /db_xref="MGI:MGI:2679259"
     exon            1..129
                     /gene="Lipk"
                     /gene_synonym="9930115F20; Lipl2"
                     /inference="alignment:Splign:2.1.0"
     exon            130..242
                     /gene="Lipk"
                     /gene_synonym="9930115F20; Lipl2"
                     /inference="alignment:Splign:2.1.0"
     CDS             141..1337
                     /gene="Lipk"
                     /gene_synonym="9930115F20; Lipl2"
                     /note="isoform 2 precursor is encoded by transcript
                     variant 2; lipase-like, ab-hydrolase domain containing 2;
                     lipase member K; lipase-like abhydrolase domain-containing
                     protein 2"
                     /codon_start=1
                     /product="lipase member K isoform 2 precursor"
                     /protein_id="NP_766425.1"
                     /db_xref="CCDS:CCDS89381.1"
                     /db_xref="GeneID:240633"
                     /db_xref="MGI:MGI:2679259"
                     /translation="MWWLLATTCCVLLSGPIDGYKQESITNPEANMNISELISYWGYP
                     YEKHDVITEDGYILGTYRIPHGKGCSRKTAPKAVVYLQHGLIASANNWICNLPNNSLA
                     FLLADSGYDVWLGNSRGNTWSRNHLRLSPKSPQYWAFSWDEMAKYDLPATVNLILEKS
                     GQKQLFYVGHSQGTTIAFIAFSTNPELAKKIRLFFALAPVATVKYTRSPMKKLTTLSR
                     KAVKVLFGDKMFSTHTWFEQFIATKVCNRKLFHQLCSNFLFSLSGFDPQNLNMSRLDV
                     YLSQSPAGTSVQNMLHWAQAVNSGQLQAFDWGNPDQNMMHFNQLTPPVYNISKMRVPT
                     AMWSGGQDVVADAKDTKNLLPKIANLIYYKEIPHYNHMDFYLGQDAPQEVYGDLIRMI
                     EESLQN"
     exon            243..360
                     /gene="Lipk"
                     /gene_synonym="9930115F20; Lipl2"
                     /inference="alignment:Splign:2.1.0"
     exon            361..559
                     /gene="Lipk"
                     /gene_synonym="9930115F20; Lipl2"
                     /inference="alignment:Splign:2.1.0"
     exon            560..669
                     /gene="Lipk"
                     /gene_synonym="9930115F20; Lipl2"
                     /inference="alignment:Splign:2.1.0"
     exon            670..806
                     /gene="Lipk"
                     /gene_synonym="9930115F20; Lipl2"
                     /inference="alignment:Splign:2.1.0"
     exon            807..953
                     /gene="Lipk"
                     /gene_synonym="9930115F20; Lipl2"
                     /inference="alignment:Splign:2.1.0"
     exon            954..1025
                     /gene="Lipk"
                     /gene_synonym="9930115F20; Lipl2"
                     /inference="alignment:Splign:2.1.0"
     exon            1026..1097
                     /gene="Lipk"
                     /gene_synonym="9930115F20; Lipl2"
                     /inference="alignment:Splign:2.1.0"
     exon            1098..2225
                     /gene="Lipk"
                     /gene_synonym="9930115F20; Lipl2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tgattgcaac atcttctgaa tcgttcggag cagagcatgt tgcgctgata ggaaactctg
       61 gaaggagctg gaatcaatct gatgctctct cacgacttga agactgactc ccagaagagc
      121 tgagctctgg cagactccaa atgtggtggc ttttagcaac aacatgttgt gtgcttcttt
      181 ccggacccat agatggctat aagcaagaaa gcatcacaaa tcctgaagcc aatatgaata
      241 ttagtgaact tatttcttac tggggctatc cttatgaaaa gcatgatgtt ataacagagg
      301 atggctacat ccttggaact taccggattc ctcatgggaa aggatgctca aggaaaacag
      361 ctccgaaggc agttgtgtat ctgcagcatg gcttaattgc atctgccaat aactggattt
      421 gcaacctgcc caacaacagc ttggctttcc ttctggccga tagtggttat gacgtgtggt
      481 tggggaacag ccgaggaaac acctggtcca gaaatcacct gagactgtca cctaaatcac
      541 cgcaatattg ggccttcagc tgggacgaga tggcgaaata tgatcttcca gctacagtca
      601 atctgatctt agagaaaagt ggacaaaagc aactcttcta tgtgggccac tcgcagggca
      661 ccaccatagc gttcatagca ttctctacga atccagagct ggctaaaaag attaggctgt
      721 ttttcgcact agctccagtg gccacagtaa aatacactcg aagcccaatg aaaaaattaa
      781 ccaccctttc caggaaagct gtcaaggtat tgtttggtga caaaatgttc tccactcaca
      841 cgtggtttga acaattcatc gctaccaaag tgtgcaaccg gaagttattc catcagctat
      901 gcagcaactt cctgttttct ctaagtggat ttgatcccca aaacttaaac atgagtcgct
      961 tggatgttta tctgtcacag agtcctgcag gaacatctgt tcagaacatg ctgcactggg
     1021 cccaggctgt caattctggt caactccaag cttttgactg gggcaaccct gaccagaaca
     1081 tgatgcactt caaccagctt acacctcctg tgtataacat ctctaagatg cgtgtcccaa
     1141 cagcaatgtg gagtggagga caggatgttg tggcagatgc taaggacact aaaaatctgc
     1201 tgcctaaaat tgccaacctt atctactaca aggagattcc acactacaat catatggatt
     1261 tttacctcgg acaggacgca ccccaggaag tttatggaga cctaattaga atgatagaag
     1321 aatctttgca aaattaaagg cactctactt ttgtaagcag gtggatgtct tgcagttata
     1381 atgaggctga ccctacagtg acacctcagt aattctcaac ttgtcccttc ttttatgtga
     1441 ggaagagaac tgaatgttct tggtagtcta cagcattttg caaagttgac agatgccata
     1501 cccctggcta ggttattcta tttggcaaag gtgatagact aggattactt acttacatga
     1561 taagacacag catcatgttt aagaattcta aggcaagagc tacttctatt ggcttgagac
     1621 aaacagatgt aatgaggaag ttcacatagc aagtgacagt ggatggtttc tcagagctga
     1681 ggatgatctc tggccaataa ccaacaagac tcaagacctt caacccgtct acatccacaa
     1741 gaaaatcaat tcttccacag ctttgcctga gtgaggaagc ctattcattt gtgaaagcag
     1801 cctggatcac aacctgtgat tgaaggggca ggggcctcca gatataacat gcctacattc
     1861 ctgaattcca aaacagtagc ataataaata tattcagttt taatttgtca actttattct
     1921 aatctgttgg cagcaataat aagctaccaa ccattaagat atagcaagta tataataaat
     1981 gtaatatttg attctattaa ttacatagtg atattgatac cataacttaa agcattacaa
     2041 tcttataatt atgtaatact gtattgcatg taacaacaca tttattacag tatattatat
     2101 gttgttatgt aatttcttga aaacttgata taatctcatc ttgatttcac ctgataacct
     2161 ttggtgtgaa tctcttcctt gaccattcag ttgtaggtta ttaatgactg aatttttcag
     2221 catgt
//
