LOCUS       NM_001252513            2082 bp    mRNA    linear   ROD 04-AUG-2023
DEFINITION  Mus musculus lipase, member I (Lipi), mRNA.
ACCESSION   NM_001252513
VERSION     NM_001252513.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2082)
  AUTHORS   Wen XY, Hegele RA, Wang J, Wang DY, Cheung J, Wilson M, Yahyapour
            M, Bai Y, Zhuang L, Skaug J, Young TK, Connelly PW, Koop BF, Tsui
            LC and Stewart AK.
  TITLE     Identification of a novel lipase gene mutated in lpd mice with
            hypertriglyceridemia and associated with dyslipidemia in humans
  JOURNAL   Hum Mol Genet 12 (10), 1131-1143 (2003)
   PUBMED   12719377
REFERENCE   2  (bases 1 to 2082)
  AUTHORS   Wen XY, Bryce DM and Breitman ML.
  TITLE     Characterization of lpd (lipid defect): a novel mutation on mouse
            chromosome 16 associated with a defect in triglyceride metabolism
  JOURNAL   Hum Mol Genet 7 (4), 743-750 (1998)
   PUBMED   9499429
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK086576.1 and AK079027.1.
            
            [WARNING] On Nov 14, 2023 this sequence was replaced by
            NM_001252513.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK086576.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381, SAMN01164137
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1154              AK086576.1         4-1157
            1155-2052           AK079027.1         566-1463
            2053-2082           AK086576.1         2058-2087
FEATURES             Location/Qualifiers
     source          1..2082
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="0"
                     /db_xref="taxon:10090"
                     /chromosome="16"
                     /map="16 43.22 cM"
     gene            1..2082
                     /gene="Lipi"
                     /gene_synonym="D930038D03Rik; lpd1"
                     /note="lipase, member I"
                     /db_xref="GeneID:320355"
                     /db_xref="MGI:MGI:2443868"
     exon            1..157
                     /gene="Lipi"
                     /gene_synonym="D930038D03Rik; lpd1"
                     /inference="alignment:Splign:2.1.0"
     CDS             112..1542
                     /gene="Lipi"
                     /gene_synonym="D930038D03Rik; lpd1"
                     /EC_number="2.7.11.30"
                     /codon_start=1
                     /product="lipase member I precursor"
                     /protein_id="NP_001239442.1"
                     /db_xref="CCDS:CCDS28272.2"
                     /db_xref="GeneID:320355"
                     /db_xref="MGI:MGI:2443868"
                     /translation="MRIYIFLCLICWARFGYLNFQSNTTGVSKDPEKKRTCLEFTKLS
                     AMNSLKDLFCPKVKINLLMYSRGNAKCAEPLFESNNSLNTRFNPAKKTVWIIHGYRPF
                     GSTPVWLSRFTKAFLKQEDVNLIVVDWNQGATTFMYSRAVRNTRRVAEILRETIENLL
                     IHGASLDNFHFIGMSLGAHISGFVGKIFHGQLGRITGLDPAGPQFSRKPSNSRLYYTD
                     AKFVDVIHTDIKSLGIGEPSGHIDFYPNGGKHQPGCPTSIFSGTNFIKCDHQRAIYLF
                     LAAFETSCNFVSFPCRSYKDYKNGLCVDCGNLYKDSCPRLGNQAKLWKEELKKKTEEW
                     PLRTTAFLDTSSQNPFCTYYFALNIVALSETMRNGSISFGLLNDLGDLEYSTLYEKSK
                     PFDNLQEVKILVQFVNDIVSISRICLTYFQSTNPYCAACQYKIQSLVLKSLTYPERPP
                     ICKYNFVLKEGTRVDLQPDECNTQME"
     exon            158..205
                     /gene="Lipi"
                     /gene_synonym="D930038D03Rik; lpd1"
                     /inference="alignment:Splign:2.1.0"
     exon            206..591
                     /gene="Lipi"
                     /gene_synonym="D930038D03Rik; lpd1"
                     /inference="alignment:Splign:2.1.0"
     exon            592..700
                     /gene="Lipi"
                     /gene_synonym="D930038D03Rik; lpd1"
                     /inference="alignment:Splign:2.1.0"
     exon            701..802
                     /gene="Lipi"
                     /gene_synonym="D930038D03Rik; lpd1"
                     /inference="alignment:Splign:2.1.0"
     exon            803..892
                     /gene="Lipi"
                     /gene_synonym="D930038D03Rik; lpd1"
                     /inference="alignment:Splign:2.1.0"
     exon            893..1060
                     /gene="Lipi"
                     /gene_synonym="D930038D03Rik; lpd1"
                     /inference="alignment:Splign:2.1.0"
     exon            1061..1165
                     /gene="Lipi"
                     /gene_synonym="D930038D03Rik; lpd1"
                     /inference="alignment:Splign:2.1.0"
     exon            1166..1277
                     /gene="Lipi"
                     /gene_synonym="D930038D03Rik; lpd1"
                     /inference="alignment:Splign:2.1.0"
     exon            1278..1454
                     /gene="Lipi"
                     /gene_synonym="D930038D03Rik; lpd1"
                     /inference="alignment:Splign:2.1.0"
     exon            1455..2082
                     /gene="Lipi"
                     /gene_synonym="D930038D03Rik; lpd1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tttttacaag aaagcttgcc ggactgagac aatcctatca cacaagaacc ttaacgaatt
       61 gcagaaattt ctggtgaatc ccactgtttc tttcacactt tctgatacca aatgagaata
      121 tacatttttc tgtgtttgat atgctgggca agatttgggt atttaaattt tcagtcgaat
      181 accactggag tttctaaaga tcctgagaag aagagaacat gtcttgaatt cacaaagtta
      241 agtgcaatga atagcttaaa agatttattt tgtcccaaag taaagataaa tctgctgatg
      301 tactcaaggg gcaacgccaa gtgtgcagag ccactctttg aatctaataa ctcactcaac
      361 acccgtttca acccagcgaa gaaaaccgtc tggattattc atgggtacag gccctttggt
      421 tccaccccag tgtggctttc taggtttact aaagcctttt tgaaacagga agatgtgaat
      481 ctcattgttg tagactggaa ccagggcgct acgactttca tgtattctag agcggttaga
      541 aataccagaa gagttgctga gattttgaga gaaaccattg agaatctttt gatccatggg
      601 gcatcacttg acaattttca tttcattggc atgagcttag gggctcatat tagtggattt
      661 gtaggaaaga tatttcatgg tcaacttgga agaattacag gtcttgaccc agctggacca
      721 caattttcta gaaagccatc gaatagcaga ttatattaca cagatgcaaa gtttgtagat
      781 gtcatccaca ctgatatcaa aagtttgggt attggagagc catcggggca cattgatttt
      841 tatccaaatg gaggaaaaca tcagccaggt tgtcctacat caattttttc aggaaccaat
      901 tttattaaat gcgaccatca gagagccatt tacttgttcc tcgcagcttt tgaaacaagc
      961 tgcaactttg tttcatttcc ttgtcgttcc tacaaagatt acaagaatgg tttgtgtgtg
     1021 gactgtggga atctttacaa agactcctgc ccaagacttg gtaatcaagc taaactatgg
     1081 aaagaagagt tgaagaaaaa aacagaagaa tggcctctta gaaccactgc atttttggat
     1141 actagtagcc aaaatccatt ttgtacctat tattttgctc tcaatatagt tgccttgagt
     1201 gaaactatga gaaatggctc aatttcattt ggtttattaa atgaccttgg agatttggaa
     1261 tactcaacac tctatgagaa gagcaagcca tttgataatc ttcaagaagt caagattctt
     1321 gttcagttcg taaatgacat tgtgagcatt tcgcgcattt gcttgacata ctttcagtcc
     1381 acaaatcctt actgtgccgc gtgccagtac aaaatacaga gccttgtgtt aaaatcactc
     1441 acatatccag aaagaccacc aatttgtaag tataattttg tattgaaaga aggaacaagg
     1501 gtagatcttc aaccagatga atgtaacacg cagatggagt gaacaccttc ttcatccagt
     1561 ttaaaattat ggactaacaa atttgtcaac tgcagcaatg tacccagcca ctgttttaga
     1621 atgcattatt taatctttaa tccaggtata tctaccttaa tttacattgg agaatcaaaa
     1681 attagcaaac aaagtatgtg catgacaaaa ctcatcctga atatatccta aaactgttcg
     1741 tttctccttg cctgcttcct aagtgaattt tagcatctaa tgtttacatc tgctgcttag
     1801 cttaataata agtggatatg taaaaagcac agctcctacg ggaaatggga agtttagtgc
     1861 tgtgccatgg agcaaattca atatcactgt acatctctat tatggaaaaa cactttttat
     1921 aaaatttgaa aatgtattgt ttagtgaaat aagctgggtt cgtgtgaacc ttgtgaatat
     1981 gaagaacttg ttatgcactg cacatatggg tgttatgcta ctgtgctcaa taaaataata
     2041 atttatggac ctacattgct taaaatgaaa tcctaaatcc tt
//
