LOCUS       NM_001368653            4389 bp    mRNA    linear   ROD 09-FEB-2025
DEFINITION  Mus musculus leucine rich repeat and Ig domain containing 4
            (Lingo4), transcript variant 2, mRNA.
ACCESSION   NM_001368653
VERSION     NM_001368653.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4389)
  AUTHORS   Um,J.W., Pramanik,G., Ko,J.S., Song,M.Y., Lee,D., Kim,H.,
            Park,K.S., Sudhof,T.C., Tabuchi,K. and Ko,J.
  TITLE     Calsyntenins function as synaptogenic adhesion molecules in concert
            with neurexins
  JOURNAL   Cell Rep 6 (6), 1096-1109 (2014)
   PUBMED   24613359
  REMARK    Erratum:[Cell Rep. 2024 Aug 27;43(8):114646. doi:
            10.1016/j.celrep.2024.114646.. PMID: 39110596]
REFERENCE   2  (bases 1 to 4389)
  AUTHORS   Homma,S., Shimada,T., Hikake,T. and Yaginuma,H.
  TITLE     Expression pattern of LRR and Ig domain-containing protein (LRRIG
            protein) in the early mouse embryo
  JOURNAL   Gene Expr Patterns 9 (1), 1-26 (2009)
   PUBMED   18848646
REFERENCE   3  (bases 1 to 4389)
  AUTHORS   Haines,B.P. and Rigby,P.W.
  TITLE     Expression of the Lingo/LERN gene family during mouse embryogenesis
  JOURNAL   Gene Expr Patterns 8 (2), 79-86 (2008)
   PUBMED   18297755
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC164562.4 and AC122808.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR7345562.3952166.1,
                                           SRR10662774.3049514.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849382, SAMN00849388
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-263               AC164562.4         200299-200561
            264-1399            AC164562.4         201456-202591
            1400-4389           AC122808.3         132152-135141       c
FEATURES             Location/Qualifiers
     source          1..4389
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 40.59 cM"
     gene            1..4389
                     /gene="Lingo4"
                     /gene_synonym="A530050P17Rik; LERN4; Lrrn6d"
                     /note="leucine rich repeat and Ig domain containing 4"
                     /db_xref="GeneID:320747"
                     /db_xref="MGI:MGI:2444651"
     exon            1..263
                     /gene="Lingo4"
                     /gene_synonym="A530050P17Rik; LERN4; Lrrn6d"
                     /inference="alignment:Splign:2.1.0"
     exon            264..4389
                     /gene="Lingo4"
                     /gene_synonym="A530050P17Rik; LERN4; Lrrn6d"
                     /inference="alignment:Splign:2.1.0"
     CDS             1720..3501
                     /gene="Lingo4"
                     /gene_synonym="A530050P17Rik; LERN4; Lrrn6d"
                     /note="leucine rich repeat neuronal 6D; leucine-rich
                     repeat and immunoglobulin-like domain containing-NOGO
                     receptor-interacting protein 4; leucine-rich repeat
                     neuronal protein 6D"
                     /codon_start=1
                     /product="leucine-rich repeat and immunoglobulin-like
                     domain containing-NOGO receptor-interacting protein 4
                     precursor"
                     /protein_id="NP_001355582.1"
                     /db_xref="GeneID:320747"
                     /db_xref="MGI:MGI:2444651"
                     /translation="MDAATAPKQAWLPWSPLLFLLLLPGGSISSCPTVCDCTSQTRAV
                     FCAHRRLDTIPGGLPLDTELLDLSGNRLWGLQRGMLSRLGQLQELDLSYNQLSTLEPG
                     AFHGLQSLLTLRLQGNRLRIVGPGIFSGLTALTLLDLRLNQIVLFLDGAFSELGSLQQ
                     LEVGDNHLVFVAPGAFAGLAKLSTITLERCNLSTVPGLALAQLPALVALRLRELDIER
                     LPAGALRGLGQLKELEIHHWPSLEALDPGSLVGLNLSSLAITRCNLSSVPFQALHHLS
                     FLRILDLSQNPISAIPARRLSPLVRLQELRLSGACLTSIAAHAFHGLTAFHLLDVADN
                     ALQTLEETAFPSPDKLVTLRLSGNPLTCDCRLLWLLRLRRRLDFGTSPPACAGPQHVQ
                     GKSLREFSDILPPGHFTCKPALIRKSGPRWVIAEEGGHAVFSCSGDGDPAPTVSWMRP
                     QGAWLGRVGRVRVLEDGTLEIRSVQLRDRGAYVCVVSNVAGNDSLRTWLEVIQVEPPN
                     GTLSDPNITMPGIPGPFFLDSRGVAMVLAVGFLPFLTSVTLCFGLIALWSKGKGRVKH
                     HMTFDFVAPRPSGDKNSGGNRVTAKLF"
ORIGIN      
        1 gagaagagga gggaaaaaaa aaaaaaaaga aaaaaatgct tcctggctct tttctctcct
       61 ttggtcttgg cagcgcgacc gcagtagcgg cggcagcaac agcagtcttg ccagccggct
      121 gatgcggcag gctgccgggc agtggggagt ggggactcag acacacgggg aaggtggaga
      181 ggccaaggtg cagctcggat gggacaggcc ccagccctgg agagatgcag cgcccaactt
      241 gatgccaccc cccagcttct ccgtttccca actgcgttat cctctgaagt ggctggagga
      301 gagtctccag aatgattctc ctggagtgta ggaaggaaag gagagctgca gctcctcctg
      361 tattctacat gcgagaaaat aggacacaca gcagaaagct aacgccacag agcccagaaa
      421 acctgaagcc tcaaagtccc gaggtgcagg acctgcagcc agggaaacac agcaagcagg
      481 ccgcctccag gagtgtcagc ttgctcctgc tcctagccct ctgtcatctc attctaatat
      541 tcctcctctc ctgtggtccc tattgcatta gcaaggcaag cagaggcact caagactaaa
      601 gatgcctcca tctctatcac catgtccagc ctccgacagt catcatggtc atcatctcct
      661 gatgctgccc aggcttctgg tgctcacttt atactgatgg gtgctgtgct tgtatccggg
      721 tgcccactgt gctacccagt ggctcccttc ctcccacgca aggcatcagg tcatgggctg
      781 tttctccccc tttatccatg cttccttggc tcacaagcca tttcttgtgt cttctcaggc
      841 agctcgggtg gaaaggggtg gaagctctcc ctcagaagca catactaact agaatcaaaa
      901 caccattaag gaaggatgta cgggaagctc aaggctgagg accccgtgaa gtatttgagt
      961 accctttaga tatcttccac atctcaaccc catctataag ggaagaggtg ctgtccttgg
     1021 ggctctggta aaggatccca atcccatcct ccagtgcccc tgcactctgt tccatgaata
     1081 atatacagcc aggcttacca tccacacaaa cagtttggga caccaaattg gctactctgg
     1141 gccttgggcc aggcggaaag agggcagaga ctagagcaga gctgaagcct gcatgtttct
     1201 tagcttctga tgatttggtc aaactaagaa ccttttccca gtcagcccag ggtcagaagc
     1261 tctctcaagt ctggatggga tctccctgat ccttgggtaa agttgtaggc acaacatatg
     1321 ggagaataag aatggggtaa gagggacata gcagagtttg tagaaagcag atgtcaggga
     1381 gatgggtcct gaggaattcc tggtctcata aatacagggg aaagcgcctt acagggagat
     1441 gcagggttct ttccccacta ctcagtccct taaactttcc actacagaaa tcagcttgac
     1501 tagggatcat gaacaggaag tacttggcca gttttctatg gctgcaaagg agagatttcc
     1561 ccattaaggt acatcaagtc tccctggttg tgtgccacac ttactggcaa gatccacctt
     1621 tcctcccctt taaggaggtt cggtgcagtg cagggtcacc accatctgaa gccacttttc
     1681 aaaagagacc atgtcatcat ctattccagg cctcagggga tggacgcagc cactgctcca
     1741 aagcaagcct ggctcccatg gtccccactc cttttcctgc tcctcctgcc tggagggagc
     1801 atcagtagct gccccactgt gtgtgactgc acctcccaga cccgggcagt attctgtgcc
     1861 cacaggcgac tggacactat tcccggaggg cttccactgg acacagaact cctggatttg
     1921 agtgggaacc gcctgtgggg gcttcagcgt ggcatgctct cccgactggg ccagctccaa
     1981 gaactggacc tcagctacaa ccagctttcc acccttgagc ctggggcttt ccatggccta
     2041 caaagtctac tcaccctgag gctgcagggc aatcgactga gaattgtggg tcctgggata
     2101 ttctcaggcc tgactgccct cacactgctg gacctccgcc tcaatcagat tgtcctcttt
     2161 ctagatggag cctttagtga gctaggtagt ctccagcagc tggaggttgg agataaccac
     2221 ctggtgtttg tggctccggg ggcttttgca gggctggcca agttaagtac catcactctg
     2281 gaacgttgca acctcagcac agtgcctggc ctagcccttg cccagctccc agcactagta
     2341 gctcttaggc ttcgagaact ggatattgag aggctaccag ctggggcact tcgagggcta
     2401 gggcagctaa aggagctgga gatccaccac tggccatctc tggaggctct ggatccaggg
     2461 agcctggttg gcctcaacct gagcagcctg gctatcaccc gctgcaatct gagctcagta
     2521 cccttccaag cactgcacca cttgagcttc ctccggatct tggatctatc tcagaatcct
     2581 atctcagcca tcccagctcg aaggctcagc cccctggtac ggctccagga gctcaggctg
     2641 tcaggagctt gcctcacctc aatcgctgct catgccttcc acggcttgac tgccttccac
     2701 ttgctggatg tagcagacaa tgctcttcag actctagagg aaacagcctt tccttctcca
     2761 gacaaactgg tcaccctgag gctgtctggt aaccccctaa cctgtgattg ccgcctcctc
     2821 tggctcctcc gcctccgccg ccgcctggac ttcggcacat ccccccctgc ttgtgctggc
     2881 ccccaacatg tccaagggaa gagcctaagg gagttttcag acattctgcc tccaggccac
     2941 ttcacttgca aaccagccct gatccgaaag tcggggcctc gttgggtcat tgcagaggag
     3001 ggcgggcatg ctgttttctc ctgctctgga gatggggacc cagcccccac tgtttcctgg
     3061 atgagaccac agggagcttg gctaggaagg gttgggagag taagggtact agaggatggt
     3121 acactggaga tccgctcggt acagctgcgg gacagggggg cctatgtctg tgtagtcagt
     3181 aatgtcgctg ggaatgactc tctgagaacc tggctggaag ttatccaagt tgagccacca
     3241 aatggcactc tgtctgaccc caacatcact atgccaggga tcccagggcc tttctttctg
     3301 gacagcaggg gtgtggctat ggtgctagca gtgggtttcc tccccttcct cacctcagtg
     3361 accctctgct ttggtctgat tgctctttgg agtaagggca agggccgggt caagcaccac
     3421 atgacttttg attttgtggc acctcggccc tcgggggaca agaactctgg gggtaatcgg
     3481 gtcactgcca agttattctg acttttccat ccatgctaaa gaccacccaa gtccacttca
     3541 gaagccaaag ggagaagtag gactaaggtc tctgaaccac agcttcatgc caaacagcac
     3601 agccttccca cacctgtcgc ctgcattatg attgctgctc tagtctgagc atggcattgc
     3661 tgcatcttct ctgagggacc cagggaactg cagacacaga cctcatcgcc agcacatccc
     3721 ctgatcccag gcacccactc acacaaggca ggaaagctga caaggctccg gtctgctctc
     3781 catgtctgta tatcctctaa tagccaggac caggtgccaa acacaaccac aagattgttt
     3841 cagaagtgga gctgagaagc atctccagct ttttagagtc tgctccaagg caggcaggca
     3901 ggcaggcagg caggcaggca ggctcccgtt cttttctgct acccggtacc caatccagcc
     3961 agtgccctta ggtacaggaa gggattccag ccaaggattc cagtgcatgc aggggagtgt
     4021 ggcctctgcc tgcaggagcc tccaccacct tcctgactgt cacaagccac tgcagtggca
     4081 gcagaaggaa acatgatctc tggaacttca tttacttcca cctacttctt cccattttag
     4141 ccactggtca tctagcctcc acctcacagg tgaggagggc caggagcctg cagatgtcag
     4201 cacttctcat ccccttggtc tgcatccttt cccctttcct ctcctctgtt gagacaaaga
     4261 aggcaagatg ctgctatctt tggagggatt cctacacaga actctcctat ttcacattgt
     4321 ccgcggttcc cagtgttgtg tattccaggc atgcttggca aagggaaagc cagaggggaa
     4381 ctcctaggg
//
