LOCUS       NM_001405334            2311 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus lin-52 DREAM MuvB core complex component (Lin52),
            transcript variant 4, mRNA.
ACCESSION   NM_001405334 XM_036157326
VERSION     NM_001405334.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2311)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2311)
  AUTHORS   Alvarez-Dominguez,J.R., Zhang,X. and Hu,W.
  TITLE     Widespread and dynamic translational control of red blood cell
            development
  JOURNAL   Blood 129 (5), 619-629 (2017)
   PUBMED   27899360
REFERENCE   3  (bases 1 to 2311)
  AUTHORS   Alvarez-Dominguez,J.R., Hu,W., Yuan,B., Shi,J., Park,S.S.,
            Gromatzky,A.A., van Oudenaarden,A. and Lodish,H.F.
  TITLE     Global discovery of erythroid long noncoding RNAs reveals novel
            regulators of red cell maturation
  JOURNAL   Blood 123 (4), 570-581 (2014)
   PUBMED   24200680
REFERENCE   4  (bases 1 to 2311)
  AUTHORS   Gineste,C., De Winter,J.M., Kohl,C., Witt,C.C., Giannesini,B.,
            Brohm,K., Le Fur,Y., Gretz,N., Vilmen,C., Pecchi,E., Jubeau,M.,
            Cozzone,P.J., Stienen,G.J., Granzier,H., Labeit,S.,
            Ottenheijm,C.A., Bendahan,D. and Gondin,J.
  TITLE     In vivo and in vitro investigations of heterozygous nebulin
            knock-out mice disclose a mild skeletal muscle phenotype
  JOURNAL   Neuromuscul Disord 23 (4), 357-369 (2013)
   PUBMED   23375831
REFERENCE   5  (bases 1 to 2311)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC120402.10 and AC110564.7.
            
            On Apr 22, 2022 this sequence version replaced XM_036157326.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR17784648.943307.1,
                                           SRR17784646.400180.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849382
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-79                AC120402.10        121680-121758
            80-165              AC120402.10        121947-122032
            166-240             AC110564.7         44329-44403
            241-278             AC110564.7         46037-46074
            279-345             AC110564.7         47707-47773
            346-429             AC110564.7         50457-50540
            430-2311            AC110564.7         117778-119659
FEATURES             Location/Qualifiers
     source          1..2311
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="12"
                     /map="12 39.22 cM"
     gene            1..2311
                     /gene="Lin52"
                     /gene_synonym="5830457H20Rik"
                     /note="lin-52 DREAM MuvB core complex component"
                     /db_xref="GeneID:217708"
                     /db_xref="MGI:MGI:3045391"
     exon            1..79
                     /gene="Lin52"
                     /gene_synonym="5830457H20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            80..165
                     /gene="Lin52"
                     /gene_synonym="5830457H20Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             147..485
                     /gene="Lin52"
                     /gene_synonym="5830457H20Rik"
                     /note="isoform 1 is encoded by transcript variant 4;
                     protein lin-52 homolog"
                     /codon_start=1
                     /product="protein lin-52 homolog isoform 1"
                     /protein_id="NP_001392263.1"
                     /db_xref="GeneID:217708"
                     /db_xref="MGI:MGI:3045391"
                     /translation="MASPTDGTDLEASLLSFEKLDRASPDLWPEQLPGVAEFAASFKS
                     PITSSPPKWMAEIERDDIDMLKELGSLTTANLMEKVRGLQNLAYQLGLDESREMTRGK
                     FLNILEKPKK"
     exon            166..240
                     /gene="Lin52"
                     /gene_synonym="5830457H20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            241..278
                     /gene="Lin52"
                     /gene_synonym="5830457H20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            279..345
                     /gene="Lin52"
                     /gene_synonym="5830457H20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            346..429
                     /gene="Lin52"
                     /gene_synonym="5830457H20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            430..2311
                     /gene="Lin52"
                     /gene_synonym="5830457H20Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2293..2298
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Lin52"
                     /gene_synonym="5830457H20Rik"
                     /note="hexamer: AATAAA"
     polyA_site      2311
                     /gene="Lin52"
                     /gene_synonym="5830457H20Rik"
                     /note="major polyA site"
ORIGIN      
        1 agacgccccc tcgacttggt actgcatagt aagcacacag ggaagacgcc ccctaaccgg
       61 gaactccgat tggctgtagg ggcgtggctt gcggatcctc gctttcccgc cgacggttgg
      121 ttacgtcacg tgacatgggc tggaagatgg cgtctcccac agacgggacg gatttggaag
      181 catctttgct aagttttgag aaacttgacc gtgcctcacc agatctctgg ccagaacagc
      241 taccaggtgt cgctgaattt gcagcttctt tcaaaagtcc catcacaagc tctccaccga
      301 aatggatggc tgagatagag cgtgatgaca ttgatatgtt gaaagaactg gggagcctca
      361 ccacagctaa cctgatggag aaggtacgag gcctacagaa cctggcctac cagctggggc
      421 tggatgagtc cagagagatg acaaggggaa aattcttgaa cattctagaa aagcccaaga
      481 agtagcaact gctcatggac tggtgtcctg aagactgtaa ccaagcttcc ttctaaatac
      541 gaccctgatg cccaccacgt gctctcttgg gaaaagcctg gaggctgagc ttcaggactg
      601 ccctcctccc ctgccccggc accctgcgcc tctgaggata ttcggtatca agaggagaga
      661 ttgttgtaac caaggagcat tgctgtttac tgagtcggct tcgtagctct ggctattggt
      721 aacacagagg tcctgtcatt ctgaaaggta ttttccagga gccccaggat ggtagagttc
      781 ctttgattct gtaatggcaa agtcagtagt gacttgttgg ttgaatgggt tctgttgcgt
      841 tgtacttgat ctcttaagca ttcatgatga ggacgtcaga gaccaactat gttctggacc
      901 agactctgca tcctgacctg tgaactctgc aagacctatt gattctatga cttccattct
      961 agaggaaaca ttagaatctt gttgaaatgc acatctgctt ttttaagtct atacctccaa
     1021 cgacactcct gctctcagga ctgtcccgtc cccacctcca gtcccactcg caggtctgag
     1081 tccagacaag aggacctctt gcagtgactt tcctgggatt agctgtagag tgaacggccc
     1141 atgctgtgcc actttgaatc ctagacctcc agaccaggaa gaaggtaaca gaaggaactc
     1201 tgggtagtct gttatatttg taagtaaaaa agtgggcagg cacggttgtg agagtcccca
     1261 catgactgaa gacaaggaag cctgattgac tggtgtgcta gccagtggta gtggcatttg
     1321 tcccctcctt cctcctctca gccgcttatc agatgctttg cttatgtgat aagaacacac
     1381 cccatgaaag tgtcttggct taactacaac tctcgcctat tttttttttt tttccaaatt
     1441 gcatatgtct gctaaattct gaaaatcttg cccctgggta aaatcgatta gacctagtct
     1501 ctcacatttt gaagagtaca gcaggttcct tgaacattgt agaaagaaaa gctctgtggc
     1561 catcgtccac tgggagtgtg gacacaggaa aagtgtggtc aagtttgtgg tcttgtctct
     1621 gttagggcac agtactcttg gggtccacag caggtccctt gactgttttt gacatttgtg
     1681 tttaatgcta gaattgatgt tggattttcc ccctcattaa tggttctgat caacacaatt
     1741 ttactttttg aaaggaaaag gcagtgaaat atataccata aaatatgaat atgagaagaa
     1801 atatattctg ctggggtact ccctacaagg gccaattggt tttaaattta attctataat
     1861 tgacattttt taatctcact gaatgcagtt aaagtgagtg tgtactcatg gtgggaacaa
     1921 tgccataatg tcagttgtcc ttcttcactc tgtttttgag agttgatgac atcaggcact
     1981 tttcagagtt tggggaaatt gaaaagtctg tggagaatac tgagctagct cccccaaact
     2041 aaagcaagtc tataatagga agccaggagt tggtgttttg atctgctaca cctcctcctc
     2101 ctatcatcct attcaccagc acttaattaa tgtaagtaga tgttttagac ttgtgctatt
     2161 tattgttttt gtattgtcat ccttagaaat gttaatagtg tatttttata ttgataatat
     2221 aaactaatgt atagtatgta tatgtatttt ataatgttag agaatacttt gtgtataatg
     2281 ttgtgtctct ataataaata tgtcccttgt a
//
