LOCUS       NM_001405333            2182 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus lin-52 DREAM MuvB core complex component (Lin52),
            transcript variant 3, mRNA.
ACCESSION   NM_001405333
VERSION     NM_001405333.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2182)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2182)
  AUTHORS   Alvarez-Dominguez,J.R., Zhang,X. and Hu,W.
  TITLE     Widespread and dynamic translational control of red blood cell
            development
  JOURNAL   Blood 129 (5), 619-629 (2017)
   PUBMED   27899360
REFERENCE   3  (bases 1 to 2182)
  AUTHORS   Alvarez-Dominguez,J.R., Hu,W., Yuan,B., Shi,J., Park,S.S.,
            Gromatzky,A.A., van Oudenaarden,A. and Lodish,H.F.
  TITLE     Global discovery of erythroid long noncoding RNAs reveals novel
            regulators of red cell maturation
  JOURNAL   Blood 123 (4), 570-581 (2014)
   PUBMED   24200680
REFERENCE   4  (bases 1 to 2182)
  AUTHORS   Gineste,C., De Winter,J.M., Kohl,C., Witt,C.C., Giannesini,B.,
            Brohm,K., Le Fur,Y., Gretz,N., Vilmen,C., Pecchi,E., Jubeau,M.,
            Cozzone,P.J., Stienen,G.J., Granzier,H., Labeit,S.,
            Ottenheijm,C.A., Bendahan,D. and Gondin,J.
  TITLE     In vivo and in vitro investigations of heterozygous nebulin
            knock-out mice disclose a mild skeletal muscle phenotype
  JOURNAL   Neuromuscul Disord 23 (4), 357-369 (2013)
   PUBMED   23375831
REFERENCE   5  (bases 1 to 2182)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC120402.10 and AC110564.7.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR17784643.630290.1,
                                           SRR17784646.1462856.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164133 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-38                AC120402.10        121995-122032
            39-113              AC110564.7         44329-44403
            114-151             AC110564.7         46037-46074
            152-218             AC110564.7         47707-47773
            219-300             AC110564.7         50457-50538
            301-2182            AC110564.7         117778-119659
FEATURES             Location/Qualifiers
     source          1..2182
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="12"
                     /map="12 39.22 cM"
     gene            1..2182
                     /gene="Lin52"
                     /gene_synonym="5830457H20Rik"
                     /note="lin-52 DREAM MuvB core complex component"
                     /db_xref="GeneID:217708"
                     /db_xref="MGI:MGI:3045391"
     exon            1..38
                     /gene="Lin52"
                     /gene_synonym="5830457H20Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             20..382
                     /gene="Lin52"
                     /gene_synonym="5830457H20Rik"
                     /note="isoform 3 is encoded by transcript variant 3;
                     protein lin-52 homolog"
                     /codon_start=1
                     /product="protein lin-52 homolog isoform 3"
                     /protein_id="NP_001392262.1"
                     /db_xref="GeneID:217708"
                     /db_xref="MGI:MGI:3045391"
                     /translation="MASPTDGTDLEASLLSFEKLDRASPDLWPEQLPGVAEFAASFKS
                     PITSSPPKWMAEIERDDIDMLKELGSLTTANLMEKVRGLQNLAYQLGLDDQRDDKGKI
                     LEHSRKAQEVATAHGLVS"
     exon            39..113
                     /gene="Lin52"
                     /gene_synonym="5830457H20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            114..151
                     /gene="Lin52"
                     /gene_synonym="5830457H20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            152..218
                     /gene="Lin52"
                     /gene_synonym="5830457H20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            219..300
                     /gene="Lin52"
                     /gene_synonym="5830457H20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            301..2182
                     /gene="Lin52"
                     /gene_synonym="5830457H20Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2164..2169
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Lin52"
                     /gene_synonym="5830457H20Rik"
                     /note="hexamer: AATAAA"
     polyA_site      2182
                     /gene="Lin52"
                     /gene_synonym="5830457H20Rik"
                     /note="major polyA site"
ORIGIN      
        1 acgtgacatg ggctggaaga tggcgtctcc cacagacggg acggatttgg aagcatcttt
       61 gctaagtttt gagaaacttg accgtgcctc accagatctc tggccagaac agctaccagg
      121 tgtcgctgaa tttgcagctt ctttcaaaag tcccatcaca agctctccac cgaaatggat
      181 ggctgagata gagcgtgatg acattgatat gttgaaagaa ctggggagcc tcaccacagc
      241 taacctgatg gagaaggtac gaggcctaca gaacctggcc taccagctgg ggctggatga
      301 ccagagagat gacaagggga aaattcttga acattctaga aaagcccaag aagtagcaac
      361 tgctcatgga ctggtgtcct gaagactgta accaagcttc cttctaaata cgaccctgat
      421 gcccaccacg tgctctcttg ggaaaagcct ggaggctgag cttcaggact gccctcctcc
      481 cctgccccgg caccctgcgc ctctgaggat attcggtatc aagaggagag attgttgtaa
      541 ccaaggagca ttgctgttta ctgagtcggc ttcgtagctc tggctattgg taacacagag
      601 gtcctgtcat tctgaaaggt attttccagg agccccagga tggtagagtt cctttgattc
      661 tgtaatggca aagtcagtag tgacttgttg gttgaatggg ttctgttgcg ttgtacttga
      721 tctcttaagc attcatgatg aggacgtcag agaccaacta tgttctggac cagactctgc
      781 atcctgacct gtgaactctg caagacctat tgattctatg acttccattc tagaggaaac
      841 attagaatct tgttgaaatg cacatctgct tttttaagtc tatacctcca acgacactcc
      901 tgctctcagg actgtcccgt ccccacctcc agtcccactc gcaggtctga gtccagacaa
      961 gaggacctct tgcagtgact ttcctgggat tagctgtaga gtgaacggcc catgctgtgc
     1021 cactttgaat cctagacctc cagaccagga agaaggtaac agaaggaact ctgggtagtc
     1081 tgttatattt gtaagtaaaa aagtgggcag gcacggttgt gagagtcccc acatgactga
     1141 agacaaggaa gcctgattga ctggtgtgct agccagtggt agtggcattt gtcccctcct
     1201 tcctcctctc agccgcttat cagatgcttt gcttatgtga taagaacaca ccccatgaaa
     1261 gtgtcttggc ttaactacaa ctctcgccta tttttttttt ttttccaaat tgcatatgtc
     1321 tgctaaattc tgaaaatctt gcccctgggt aaaatcgatt agacctagtc tctcacattt
     1381 tgaagagtac agcaggttcc ttgaacattg tagaaagaaa agctctgtgg ccatcgtcca
     1441 ctgggagtgt ggacacagga aaagtgtggt caagtttgtg gtcttgtctc tgttagggca
     1501 cagtactctt ggggtccaca gcaggtccct tgactgtttt tgacatttgt gtttaatgct
     1561 agaattgatg ttggattttc cccctcatta atggttctga tcaacacaat tttacttttt
     1621 gaaaggaaaa ggcagtgaaa tatataccat aaaatatgaa tatgagaaga aatatattct
     1681 gctggggtac tccctacaag ggccaattgg ttttaaattt aattctataa ttgacatttt
     1741 ttaatctcac tgaatgcagt taaagtgagt gtgtactcat ggtgggaaca atgccataat
     1801 gtcagttgtc cttcttcact ctgtttttga gagttgatga catcaggcac ttttcagagt
     1861 ttggggaaat tgaaaagtct gtggagaata ctgagctagc tcccccaaac taaagcaagt
     1921 ctataatagg aagccaggag ttggtgtttt gatctgctac acctcctcct cctatcatcc
     1981 tattcaccag cacttaatta atgtaagtag atgttttaga cttgtgctat ttattgtttt
     2041 tgtattgtca tccttagaaa tgttaatagt gtatttttat attgataata taaactaatg
     2101 tatagtatgt atatgtattt tataatgtta gagaatactt tgtgtataat gttgtgtctc
     2161 tataataaat atgtcccttg ta
//
