LOCUS       NM_198637                941 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus ligand of ATE1 (Liat1), mRNA.
ACCESSION   NM_198637 XM_354630
VERSION     NM_198637.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 941)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 941)
  AUTHORS   Arva,A., Kasu,Y.A.T., Duncan,J., Alkhatatbeh,M.A. and Brower,C.S.
  TITLE     The Ligand of Ate1 is intrinsically disordered and participates in
            nucleolar phase separation regulated by Jumonji Domain Containing 6
  JOURNAL   Proc Natl Acad Sci U S A 118 (1) (2021)
   PUBMED   33443146
  REMARK    GeneRIF: The Ligand of Ate1 is intrinsically disordered and
            participates in nucleolar phase separation regulated by Jumonji
            Domain Containing 6.
REFERENCE   3  (bases 1 to 941)
  AUTHORS   Brower,C.S., Rosen,C.E., Jones,R.H., Wadas,B.C., Piatkov,K.I. and
            Varshavsky,A.
  TITLE     Liat1, an arginyltransferase-binding protein whose evolution among
            primates involved changes in the numbers of its 10-residue repeats
  JOURNAL   Proc Natl Acad Sci U S A 111 (46), E4936-E4945 (2014)
   PUBMED   25369936
  REMARK    GeneRIF: Liat1 interacts with Ate1 but does not appear to be its
            arginylation substrate. It has a higher affinity for the isoforms
            Ate1 1A7A and 1B7A. It stimulated N-terminal arginylation of a
            model substrate by Ate1. Sequelogs of other species are compared.
REFERENCE   4  (bases 1 to 941)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BQ931096.1 and BC049758.1.
            
            On Oct 26, 2007 this sequence version replaced NM_198637.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC049758.1, BQ931096.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849381
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-571               BQ931096.1         16-586
            572-941             BC049758.1         511-880
FEATURES             Location/Qualifiers
     source          1..941
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 45.92 cM"
     gene            1..941
                     /gene="Liat1"
                     /gene_synonym="1700016K19Rik"
                     /note="ligand of ATE1"
                     /db_xref="GeneID:74230"
                     /db_xref="MGI:MGI:1921480"
     exon            1..355
                     /gene="Liat1"
                     /gene_synonym="1700016K19Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             151..837
                     /gene="Liat1"
                     /gene_synonym="1700016K19Rik"
                     /note="ligand of ATE1 protein"
                     /codon_start=1
                     /product="protein LIAT1"
                     /protein_id="NP_941039.1"
                     /db_xref="CCDS:CCDS25059.1"
                     /db_xref="GeneID:74230"
                     /db_xref="MGI:MGI:1921480"
                     /translation="MAGRGGTGAAEYGEEGEEEEEEEAREGGAEGSPGSKLPPIVGTA
                     SELAKRKVKKKKKKKKTKGSGKGDADKHHSRGRKNQPLSSSFHDILNPHKDHGLRAEP
                     RDKEENRQTLPYSYSINHPCFAEIEDTLSSQINESLRWDGILTDPEAEKERIRIYKLN
                     RRKRYRLMALKCFHSDPCVEESVENLPYLSDKDCSPCSKQPSSKGDHAHSYFEASKLL
                     HPELATTVAE"
     exon            356..921
                     /gene="Liat1"
                     /gene_synonym="1700016K19Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      899..904
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Liat1"
                     /gene_synonym="1700016K19Rik"
                     /note="hexamer: AATAAA"
     regulatory      905..910
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Liat1"
                     /gene_synonym="1700016K19Rik"
                     /note="hexamer: AAGAAA"
     polyA_site      918
                     /gene="Liat1"
                     /gene_synonym="1700016K19Rik"
     polyA_site      921
                     /gene="Liat1"
                     /gene_synonym="1700016K19Rik"
                     /note="major polyA site"
ORIGIN      
        1 gtgccccttg cggcaacttc ctagttgtgc gcgtggcgtg gagcggtcgc catggagacg
       61 cgtggtctga gcaagcagtg agcgcctgga gcccgccagg tgcgggtcct ctgctgtttc
      121 cgggcacgca ggtcggggac ccgcgggcgg atggccggcc gtggtgggac cggtgcggcg
      181 gagtatggtg aggagggcga ggaagaggag gaggaggagg cgcgggaagg cggagctgag
      241 ggctccccgg ggtccaagct gcctcccatc gtgggcaccg cctccgagct ggccaaacgg
      301 aaggtgaaga agaaaaagaa gaagaaaaag actaaaggat cgggcaaggg cgacgcagat
      361 aaacatcaca gtcgagggcg gaagaatcag ccgctttctt catctttcca tgacatctta
      421 aatccccaca aagaccatgg cttgagagca gagcccagag acaaagagga aaataggcaa
      481 acccttccct attcgtacag cattaatcac ccctgctttg ccgaaataga agacaccctt
      541 tccagccaga tcaacgagag tctgcgttgg gatgggattc tcaccgaccc tgaggcagaa
      601 aaggaaagga tccgcatcta caagctcaac cgaaggaagc ggtaccgcct catggccctc
      661 aagtgcttcc attccgaccc ctgcgtggag gagagcgtgg agaatctgcc ctacctctca
      721 gacaaagact gcagcccctg cagcaagcag cccagctcta agggcgacca cgcgcatagc
      781 tactttgagg cctcgaagct cctgcaccca gaattagcca ccactgtggc agagtgacat
      841 ctgtccttcc tgctgccaat ttcctccttg ccacacattt atgtttaaaa agaatcataa
      901 taaaaagaaa tcagacctga aaaaaaaaaa aaaaaaaaaa a
//
