LOCUS       NM_175386               2107 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus LHFPL tetraspan subfamily member 6 (Lhfpl6), mRNA.
ACCESSION   NM_175386
VERSION     NM_175386.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2107)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2107)
  AUTHORS   Mesner,L.D., Calabrese,G.M., Al-Barghouthi,B., Gatti,D.M.,
            Sundberg,J.P., Churchill,G.A., Godfrey,D.A., Ackert-Bicknell,C.L.
            and Farber,C.R.
  TITLE     Mouse genome-wide association and systems genetics identifies Lhfp
            as a regulator of bone mass
  JOURNAL   PLoS Genet 15 (5), e1008123 (2019)
   PUBMED   31042701
  REMARK    GeneRIF: Lhfp is a regulator of osteoblast activity and bone mass.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2107)
  AUTHORS   Zhao,F., Zhou,J., Li,R., Dudley,E.A. and Ye,X.
  TITLE     Novel function of LHFPL2 in female and male distal reproductive
            tract development
  JOURNAL   Sci Rep 6, 23037 (2016)
   PUBMED   26964900
  REMARK    Publication Status: Online-Only
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC052079.1.
            
            On Aug 28, 2003 this sequence version replaced NM_175386.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC052079.1, AK159549.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2107
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 24.17 cM"
     gene            1..2107
                     /gene="Lhfpl6"
                     /gene_synonym="2810489O06Rik; Lhfp"
                     /note="LHFPL tetraspan subfamily member 6"
                     /db_xref="GeneID:108927"
                     /db_xref="MGI:MGI:1920048"
     exon            1..228
                     /gene="Lhfpl6"
                     /gene_synonym="2810489O06Rik; Lhfp"
                     /inference="alignment:Splign:2.1.0"
     exon            229..801
                     /gene="Lhfpl6"
                     /gene_synonym="2810489O06Rik; Lhfp"
                     /inference="alignment:Splign:2.1.0"
     CDS             417..1019
                     /gene="Lhfpl6"
                     /gene_synonym="2810489O06Rik; Lhfp"
                     /EC_number="3.6.5.4"
                     /note="LHFPL tetraspan subfamily member 6 protein; lipoma
                     HMGIC fusion partner"
                     /codon_start=1
                     /product="LHFPL tetraspan subfamily member 6 protein
                     precursor"
                     /protein_id="NP_780595.1"
                     /db_xref="CCDS:CCDS17344.1"
                     /db_xref="GeneID:108927"
                     /db_xref="MGI:MGI:1920048"
                     /translation="MASSLTCTGVIWALLSFLSAATSCVGFFMPYWLWGSQLGKPVSF
                     GTFRRCSYPVHDESRQMMVMVEECGRYASFQGIPSTEWRICTIVTGLGCGLLLLVALT
                     ALMGCCVSELISRTVGRVAGGIQFLGGLLIGAGCALYPLGWDSEEVRQTCGYISGQFD
                     LGKCEIGWAYYCTGAGAAAAMLLCTWMACFSGKKQKHYPY"
     exon            802..900
                     /gene="Lhfpl6"
                     /gene_synonym="2810489O06Rik; Lhfp"
                     /inference="alignment:Splign:2.1.0"
     exon            901..2089
                     /gene="Lhfpl6"
                     /gene_synonym="2810489O06Rik; Lhfp"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2068..2073
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Lhfpl6"
                     /gene_synonym="2810489O06Rik; Lhfp"
                     /note="hexamer: AATAAA"
     polyA_site      2089
                     /gene="Lhfpl6"
                     /gene_synonym="2810489O06Rik; Lhfp"
                     /note="major polyA site"
ORIGIN      
        1 ccggcatcca ccgtgttccc gggccgcacg gccgcagccg gcgggctctc cgggtgggtc
       61 cccctgaccc tccaccccag ctctccagac tcgcctcgat ctccgtcggg atagtggcaa
      121 aggcaagaaa gacagtcttc tttggtgccg cgctgtcccc gccagggaaa gacagcaagt
      181 tgtgctgcgc ccgggactcg cgagggaccg cggccgccgc ccgaccgggg gccaccagcc
      241 atcttcactc caaagtatga gaagctgatc gcggtaatac tgaaactctg ttacggcaag
      301 tagctacata cgccttgaag agcggtggac tacctgggag tttcttgtga ctacacgcct
      361 tccttcacac ctttagtgca atcacagcgg accctcattg cactgcctgt tggaagatgg
      421 cgtccagcct gacttgtact ggggtgatct gggctttgct ttccttcctt tccgctgcca
      481 cctcctgtgt ggggttcttc atgccatact ggctctgggg gtctcagcta ggcaagcctg
      541 tatcctttgg cactttccgg aggtgctcct atcctgttca cgatgagagt cggcagatga
      601 tggtgatggt ggaggagtgt gggcgctatg cctccttcca gggcatcccc agcaccgagt
      661 ggaggatctg taccatagtg acaggccttg gctgcggcct gttgctcctg gtggctctca
      721 ctgccctgat gggttgctgc gtgtcggaac tcatctccag gactgtagga agagtggctg
      781 ggggaatcca gttcctgggg ggcttgctga ttggtgctgg ctgtgccctc taccccttgg
      841 gctgggacag tgaggaagtc cggcagactt gtggctacat ctctggccag tttgacttgg
      901 gcaagtgtga gatcggctgg gcctactact gcaccggggc aggggctgcg gctgccatgc
      961 tgctgtgtac atggatggct tgcttctcag gcaagaagca aaagcactac ccctactgag
     1021 gtggtcaaga acgagctgag gagaggacag accaccggag accagagggc ccgaagcatc
     1081 cagcgacttt cacaaggtgg aatagtggtt gtaaacccag aacagtgtta atgtgatgaa
     1141 attcggttga atctggaaca ttctatagga agggagggtg gtggggacat tgtcattgtc
     1201 aaaagcatgg agaataaggg acggtggagg aaaatggacc aaaggctaaa aacattgcag
     1261 ggcattgttg tttctattcc acagagtacc gttaatgtat atcatatacc cagcaaatct
     1321 atatatgcaa acgaggatct catttttgtt ctccttcaaa aagatgagga ctaggggagt
     1381 caaaagggct agtagaaaca gtattatctt aggaagcagg atgagtaccc tgcagacatt
     1441 ccctgtagat gaggattgag cctgaaagca catgagtacg tgcacacata tgcacacatc
     1501 atattcacat accacatgca catgttatat gcacaggtca tacgcacatg ccatatgcat
     1561 acatcacacg cacacatcat acgcatatgt catcacacca ctgcacaggg ggtcagctgt
     1621 gtactgttgc tcctgtttct tttctttttt ttaatataca tcaggacagc atcatcacta
     1681 agcatacatt aagcctagtc catggaccaa tatgccactc tatcagtatt tttgatatcc
     1741 tgcataaact ctttatgccc gcagcatatc ttttagtgtt tatgcaaatc tttagaggaa
     1801 agccttcaaa tgtcaatgtt attcaaagac acacagtagt gaactgagta gcttctgctg
     1861 taacaacctc acgtagaaca ggacagcttt tgtctactat aggtgagaat tcagttgcag
     1921 atttgagagt gaggagagct ttctccagtt gttggatctt cttttctttt ctccattatt
     1981 ctactgtgct ataccatgat tatttcaata ttcattttgt aaagggaaaa aaaagtacta
     2041 ttttgtttgt atttgaaaag ctctgtgaat aaattctctt tgatcaataa aaaaaaaaaa
     2101 aaaaaaa
//
