LOCUS       NM_013582               6866 bp    mRNA    linear   ROD 10-DEC-2024
DEFINITION  Mus musculus luteinizing hormone/choriogonadotropin receptor
            (Lhcgr), transcript variant 1, mRNA.
ACCESSION   NM_013582
VERSION     NM_013582.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6866)
  AUTHORS   Kanatsu-Shinohara,M., Morimoto,H., Liu,T., Tamura,M. and
            Shinohara,T.
  TITLE     Sendai virus-mediated RNA delivery restores fertility to congenital
            and chemotherapy-induced infertile female mice
  JOURNAL   PNAS Nexus 3 (9), pgae375 (2024)
   PUBMED   39262851
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6866)
  AUTHORS   Bhatnager,R., Gaba,K. and Dang,A.S.
  TITLE     Comprehensive Analysis of Damage Associated SNPs of Luteinizing
            Hormone and Its Receptor: A Computational Approach
  JOURNAL   Am J Reprod Immunol 91 (6), e13886 (2024)
   PUBMED   39031603
  REMARK    GeneRIF: Comprehensive Analysis of Damage Associated SNPs of
            Luteinizing Hormone and Its Receptor: A Computational Approach.
REFERENCE   3  (bases 1 to 6866)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   4  (bases 1 to 6866)
  AUTHORS   Owen,C.M. and Jaffe,L.A.
  TITLE     Luteinizing hormone stimulates ingression of mural granulosa cells
            within the mouse preovulatory follicledagger
  JOURNAL   Biol Reprod 110 (2), 288-299 (2024)
   PUBMED   37847612
REFERENCE   5  (bases 1 to 6866)
  AUTHORS   Xia,K., Wang,F., Tan,Z., Zhang,S., Lai,X., Ou,W., Yang,C., Chen,H.,
            Peng,H., Luo,P., Hu,A., Tu,X., Wang,T., Ke,Q., Deng,C. and
            Xiang,A.P.
  TITLE     Precise Correction of Lhcgr Mutation in Stem Leydig Cells by Prime
            Editing Rescues Hereditary Primary Hypogonadism in Mice
  JOURNAL   Adv Sci (Weinh) 10 (29), e2300993 (2023)
   PUBMED   37697644
  REMARK    GeneRIF: Precise Correction of Lhcgr Mutation in Stem Leydig Cells
            by Prime Editing Rescues Hereditary Primary Hypogonadism in Mice.
REFERENCE   6  (bases 1 to 6866)
  AUTHORS   Atger,M., Misrahi,M., Sar,S., Le Flem,L., Dessen,P. and Milgrom,E.
  TITLE     Structure of the human luteinizing hormone-choriogonadotropin
            receptor gene: unusual promoter and 5' non-coding regions
  JOURNAL   Mol Cell Endocrinol 111 (2), 113-123 (1995)
   PUBMED   7556872
REFERENCE   7  (bases 1 to 6866)
  AUTHORS   Gudermann,T., Birnbaumer,M. and Birnbaumer,L.
  TITLE     Homologous desensitization of the murine luteinizing hormone
            receptor expressed in L cells
  JOURNAL   Mol Cell Endocrinol 110 (1-2), 125-135 (1995)
   PUBMED   7672443
REFERENCE   8  (bases 1 to 6866)
  AUTHORS   Huhtaniemi,I.T., Eskola,V., Pakarinen,P., Matikainen,T. and
            Sprengel,R.
  TITLE     The murine luteinizing hormone and follicle-stimulating hormone
            receptor genes: transcription initiation sites, putative promoter
            sequences and promoter activity
  JOURNAL   Mol Cell Endocrinol 88 (1-3), 55-66 (1992)
   PUBMED   1459341
REFERENCE   9  (bases 1 to 6866)
  AUTHORS   Gudermann,T., Birnbaumer,M. and Birnbaumer,L.
  TITLE     Evidence for dual coupling of the murine luteinizing hormone
            receptor to adenylyl cyclase and phosphoinositide breakdown and
            Ca2+ mobilization. Studies with the cloned murine luteinizing
            hormone receptor expressed in L cells
  JOURNAL   J Biol Chem 267 (7), 4479-4488 (1992)
   PUBMED   1311310
REFERENCE   10 (bases 1 to 6866)
  AUTHORS   McFarland,K.C., Sprengel,R., Phillips,H.S., Kohler,M.,
            Rosemblit,N., Nikolics,K., Segaloff,D.L. and Seeburg,P.H.
  TITLE     Lutropin-choriogonadotropin receptor: an unusual member of the G
            protein-coupled receptor family
  JOURNAL   Science 245 (4917), 494-499 (1989)
   PUBMED   2502842
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC154459.2.
            
            On Jul 13, 2018 this sequence version replaced NM_013582.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: M81310.1, SRR13422598.1601554.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-216               AC154459.2         122312-122527       c
            217-288             AC154459.2         102525-102596       c
            289-363             AC154459.2         100350-100424       c
            364-438             AC154459.2         97766-97840         c
            439-513             AC154459.2         95661-95735         c
            514-591             AC154459.2         95495-95572         c
            592-660             AC154459.2         88856-88924         c
            661-735             AC154459.2         86064-86138         c
            736-921             AC154459.2         84257-84442         c
            922-1002            AC154459.2         80616-80696         c
            1003-6866           AC154459.2         67787-73650         c
FEATURES             Location/Qualifiers
     source          1..6866
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 58.35 cM"
     gene            1..6866
                     /gene="Lhcgr"
                     /gene_synonym="Gpcr19-rs1; LH-R; LH/CG-R; Lhr; LSH-R"
                     /note="luteinizing hormone/choriogonadotropin receptor"
                     /db_xref="GeneID:16867"
                     /db_xref="MGI:MGI:96783"
     exon            1..216
                     /gene="Lhcgr"
                     /gene_synonym="Gpcr19-rs1; LH-R; LH/CG-R; Lhr; LSH-R"
                     /inference="alignment:Splign:2.1.0"
     CDS             44..2146
                     /gene="Lhcgr"
                     /gene_synonym="Gpcr19-rs1; LH-R; LH/CG-R; Lhr; LSH-R"
                     /note="isoform 1 precursor is encoded by transcript
                     variant 1; lutropin-choriogonadotropic hormone receptor"
                     /codon_start=1
                     /product="lutropin-choriogonadotropic hormone receptor
                     isoform 1 precursor"
                     /protein_id="NP_038610.1"
                     /db_xref="CCDS:CCDS29025.1"
                     /db_xref="GeneID:16867"
                     /db_xref="MGI:MGI:96783"
                     /translation="MGRRVPALRQLLVLAMLVLKQSQLHSPELSGSRCPEPCDCAPDG
                     ALRCPGPRAGLARLSLTYLPVKVIPSQAFRGLNEVVKIEISQSDSLERIEANAFDNLL
                     NLSEILIQNTKNLLYIEPGAFTNLPRLKYLSICNTGIRTLPDVSKISSSEFNFILEIC
                     DNLYITTIPGNAFQGMNNESITLKLYGNGFEEVQSHAFNGTTLISLELKENIYLEKMH
                     SGTFQGATGPSILDVSSTKLQALPSHGLESIQTLIATSSYSLKTLPSREKFTSLLVAT
                     LTYPSHCCAFRNLPKKEQNFSFSIFENFSKQCESTVREANNETLYSAIFEENELSGWD
                     YDYDFCSPKTLQCTPEPDAFNPCEDIMGYAFLRVLIWLINILAIFGNLTVLFVLLTSR
                     YKLTVPRFLMCNLSFADFCMGLYLLLIASVDSQTKGQYYNHAIDWQTGSGCSAAGFFT
                     VFASELSVYTLTVITLERWHTITYAVQLDQKLRLRHAIPIMLGGWIFSTLMATLPLVG
                     VSSYMKVSICLPMDVESTLSQVYILSILLLNAVAFVVICACYVRIYFAVQNPELTAPN
                     KDTKIAKKMAILIFTDFTCMAPISFFAISAAFKVPLITVTNSKVLLVLFYPVNSCANP
                     FLYAVFTKAFQRDFFLLLSRFGCCKHRAELYRRKEFSACTFNSKNGFPRSSKPSQAAL
                     KLSIVHCQQPTPPRVLIQ"
     exon            217..288
                     /gene="Lhcgr"
                     /gene_synonym="Gpcr19-rs1; LH-R; LH/CG-R; Lhr; LSH-R"
                     /inference="alignment:Splign:2.1.0"
     exon            289..363
                     /gene="Lhcgr"
                     /gene_synonym="Gpcr19-rs1; LH-R; LH/CG-R; Lhr; LSH-R"
                     /inference="alignment:Splign:2.1.0"
     exon            364..438
                     /gene="Lhcgr"
                     /gene_synonym="Gpcr19-rs1; LH-R; LH/CG-R; Lhr; LSH-R"
                     /inference="alignment:Splign:2.1.0"
     exon            439..513
                     /gene="Lhcgr"
                     /gene_synonym="Gpcr19-rs1; LH-R; LH/CG-R; Lhr; LSH-R"
                     /inference="alignment:Splign:2.1.0"
     exon            514..591
                     /gene="Lhcgr"
                     /gene_synonym="Gpcr19-rs1; LH-R; LH/CG-R; Lhr; LSH-R"
                     /inference="alignment:Splign:2.1.0"
     exon            592..660
                     /gene="Lhcgr"
                     /gene_synonym="Gpcr19-rs1; LH-R; LH/CG-R; Lhr; LSH-R"
                     /inference="alignment:Splign:2.1.0"
     exon            661..735
                     /gene="Lhcgr"
                     /gene_synonym="Gpcr19-rs1; LH-R; LH/CG-R; Lhr; LSH-R"
                     /inference="alignment:Splign:2.1.0"
     exon            736..921
                     /gene="Lhcgr"
                     /gene_synonym="Gpcr19-rs1; LH-R; LH/CG-R; Lhr; LSH-R"
                     /inference="alignment:Splign:2.1.0"
     exon            922..1002
                     /gene="Lhcgr"
                     /gene_synonym="Gpcr19-rs1; LH-R; LH/CG-R; Lhr; LSH-R"
                     /inference="alignment:Splign:2.1.0"
     exon            1003..6866
                     /gene="Lhcgr"
                     /gene_synonym="Gpcr19-rs1; LH-R; LH/CG-R; Lhr; LSH-R"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2457..2462
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Lhcgr"
                     /gene_synonym="Gpcr19-rs1; LH-R; LH/CG-R; Lhr; LSH-R"
                     /note="hexamer: AATATA"
     polyA_site      2482
                     /gene="Lhcgr"
                     /gene_synonym="Gpcr19-rs1; LH-R; LH/CG-R; Lhr; LSH-R"
                     /note="major polyA site"
     regulatory      2571..2576
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Lhcgr"
                     /gene_synonym="Gpcr19-rs1; LH-R; LH/CG-R; Lhr; LSH-R"
                     /note="hexamer: AATAAA"
     polyA_site      2591
                     /gene="Lhcgr"
                     /gene_synonym="Gpcr19-rs1; LH-R; LH/CG-R; Lhr; LSH-R"
                     /note="major polyA site"
     regulatory      6275..6280
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Lhcgr"
                     /gene_synonym="Gpcr19-rs1; LH-R; LH/CG-R; Lhr; LSH-R"
                     /note="hexamer: AATAAA"
     polyA_site      6303
                     /gene="Lhcgr"
                     /gene_synonym="Gpcr19-rs1; LH-R; LH/CG-R; Lhr; LSH-R"
                     /note="major polyA site"
ORIGIN      
        1 atactggcct agccaccgga gctcacactc aggctggcgg gccatggggc ggcgggtccc
       61 ggctctgaga cagctgctgg tgctggcaat gctggtgctg aagcagtcac agctgcactc
      121 tccagagttg tcagggtcgc gctgccctga gccctgcgac tgcgcgccgg atggtgccct
      181 gcgctgccct ggccctcgag ctggcctcgc ccgactatct ctcacctatc tccctgtcaa
      241 agtaatccca tcacaagctt tcaggggact taatgaggtc gtaaaaattg aaatctctca
      301 gagtgattcc ctggaaagga tagaagctaa tgcctttgac aacctcctca atctgtctga
      361 aatactgatc cagaacacca aaaacctgct atacattgaa cccggtgctt ttacaaacct
      421 ccctcggtta aaatacctga gcatctgtaa cacaggcatc cggaccctcc cagatgtttc
      481 gaagatctct tcctctgaat ttaatttcat tctggaaatc tgtgataact tatacataac
      541 caccatacca gggaacgctt tccaagggat gaataatgag tccatcacgc tgaaactgta
      601 tggaaatggg tttgaagaag tacaaagcca tgcattcaat gggacgacgc taatctcgct
      661 ggagttaaaa gaaaacatct acctggagaa gatgcacagt ggcaccttcc agggggccac
      721 ggggcccagc atcctggatg tctcttccac caaattgcag gccctgccga gccacgggct
      781 ggagtccatt cagacgctca tcgccacgtc atcctactca ctgaaaactc tgccctccag
      841 agaaaaattc accagcctac tggttgccac gctgacctac cctagccact gctgtgcttt
      901 caggaatttg ccgaagaaag aacagaattt ttcattttcc atttttgaaa acttttccaa
      961 acaatgtgaa agcacagtta gagaagcgaa taacgagacg ctttattctg ccatctttga
     1021 ggagaatgaa ctcagtggct gggattacga ttatgacttc tgttcaccca agacactcca
     1081 atgtactcca gaaccagatg ctttcaatcc ctgtgaagat attatgggct atgccttcct
     1141 tagggtgttg atttggctaa ttaatatact agccatcttt ggcaacttga cagtcctctt
     1201 tgttctcctg accagtcgtt ataaactgac ggtgccccgc ttcctcatgt gtaatctctc
     1261 ctttgcagac ttttgcatgg ggctctacct gctgctcatt gcctcagtag actcccaaac
     1321 aaaaggccag tactataacc atgccataga ctggcagaca gggagtggct gcagtgcagc
     1381 tggcttcttt actgtgttcg ccagtgaact ttctgtctat acccttacag tcatcactct
     1441 ggaaaggtgg cacaccatca cctatgctgt tcagctggac caaaagctga ggctgagaca
     1501 tgccatccca attatgctcg gaggatggat tttttctacc ctgatggcca cattgcccct
     1561 tgtgggtgtc agcagttaca tgaaagtcag catctgcctc cccatggatg tggaatccac
     1621 tctgtcacaa gtctacatat tatccatctt gctcctcaat gcagtggcct ttgtcgtcat
     1681 ctgtgcttgc tacgttagga tatactttgc agttcaaaat ccagagctga cggctcctaa
     1741 caaggacaca aaaattgcta agaagatggc catcctcatc ttcacagact tcacatgcat
     1801 ggcacccatc tcattctttg ccatctcagc tgccttcaaa gtacccctta tcactgtcac
     1861 caactcaaaa gttctgctgg tcctttttta tcctgtcaat tcttgtgcca acccatttct
     1921 gtacgcagtg ttcacgaagg catttcagag agatttcttt ctcttgctga gcagatttgg
     1981 ttgctgtaag caccgggctg aactttacag aaggaaggaa ttttctgcat gtaccttcaa
     2041 ctccaaaaac ggctttccaa gatcaagtaa gccttcccag gctgccctga agttatccat
     2101 agtgcactgt caacaaccta cacctccaag agtgttaatt cagtaactgc attactgaat
     2161 tgtatctaaa tatgttcccc ccaaaaaagt ccacccaaat tagtcacttt aatataatgt
     2221 gttttagaaa aaatatttat ctttaagcac ttcaggtgaa ttgaaacctg cttcaaaggg
     2281 tggcccaaga cacttggtga cataaatttc agaagggttt agaaaatttt ttataataat
     2341 ttagaaagaa tagtttttgt ttgttgaatc taatattaag aaaatctaag ttgttgtcat
     2401 tttccatgtc tcttgatctt tttcacttca atctgtgatt catgttgcca tctctaaata
     2461 tatattcata acagactgga aatttaaagt ggtctttgtc ctcagatagt ttgataaata
     2521 cattcaagag atgcactgtg cagcgtgata gctgttagcc ttacatggta aataaaagtt
     2581 tcttagccat atcccaagtg cttcgtgggt ctcactagta ataggaggca cagattcaaa
     2641 ctgttttcat cagtgcaagg aattctatta gacagctcta ttctagagac ttctatttcc
     2701 catttacact ctactcactt agctttccat ctgaaggcac atttctgcat acttgtttgg
     2761 cttacagagc atgaacccct tgtgggcagg aacccacctc agtttcctca tctcctatct
     2821 ggggatcttg gaaatgatac acagcaagtg tgcctagcta gttaaacttc tagagataca
     2881 tggagaaatg tttcttagta tatttttttg atcgttacag gctttatgtt tttttgtccc
     2941 catcccggta tctcttctca gagttcttca ctcccttttg cctctgagag ggtgcccctc
     3001 ccagagaatt ccccctcccc tagggcatta agtttctgca agattaggca catcctctcc
     3061 cactgaggcc atacagggca gtcctctgct acatatgagc caggggggct tcagaccagc
     3121 ccatgtatgc tctctggttg gtggcttagt ctctgggaac tccaggtgtc aaggtgagtt
     3181 gacactgttg gtgttccttt ggggttgcca accccttcag ttacttcagt cctccccctc
     3241 actcttccat agggtacctt tgcaccttta agaaaacaaa atattcaaat ttttaaaatt
     3301 attaacccat tatttctatg cttggcactt tattgggaaa tatatctaat attgtcagaa
     3361 gcacttgtta cttcctacag ctggctcttg caggacaccc gactgatagg tctcacagcg
     3421 cagcttttgt ttgccccttt tccttcttga ttgaaagttc attacacaca cagcatcttg
     3481 gtgagtgtat tatataatct caccaactga atcttcagaa aactctacag ttcagatgcc
     3541 attatattat acaagaaaaa aagaccatca ccatttttga aagtactgaa aactaggaaa
     3601 agattcaagt aaaaagattc aatctcaaag gtcctcacaa agcttagcct ctttaatgat
     3661 tcccatactg ttaaaaaaaa ttcattgttt tccaagagtt actttgcgtt gaaataaatt
     3721 ttaaaaaatt ggatacactg acagatggac agacaaatac ttattaggta gctaggtttt
     3781 gttatttaaa agcttatata cattcaacgt tctttaagtt ttcccaatat tttattatga
     3841 acattttcaa atgtacagaa atgttggaga aactgtatag tgaacaccca tacatcaaca
     3901 ctatttacag caagccatat gttactatat tgactttcat acattactat gcaattatct
     3961 gttatttatc tgtcaatcaa tgtcttacat attttgatat tttaaagtaa tttgcaggta
     4021 ttagtcttac acaagagaat acattataca cccccgtgta aatgaatgtc agtactcata
     4081 ttcactgagt ataatatata atatttattt acgttgttgg tataatctta aatgtgccac
     4141 ttgagttttg agaacagcac acacctatgt cagccacact gtgtcaggat ttagtctagt
     4201 tagttagaga gttcctcact gtggatgatg gccgatattc tccacaggct agtgtttcct
     4261 gccctagatg gcatataaat gcaggtctat aaaacatgtg ctttttcaca tggctttgga
     4321 cttagtttat tattcttact attcatccac ttgattgctt gaatccattt attccttctc
     4381 attgctaact gaaattctac cgtattaata ttaaaattcc tttctcctac tgatagctat
     4441 cttggctatt tccagctttc aacttcctgt gagcatttta ttaaataaat gtctaaccat
     4501 aactagattc aacacattta ctttgctttc atttcttaag tcattacata aaatgattca
     4561 aagaagattg taagatttat aaagagaaat ctcttctgtg tttacattta tgacctctct
     4621 gctccataaa gaacgacttg gttcaggtgg agtcctttct tgctcatctt agaatctgtc
     4681 tcagcaacac atcagaatac taactcatca aactacttat ataactacat gatagtcttt
     4741 ctgattcata aaccccagga aaaaaacaat gtagtaagaa aaagtaaaca ggcactctgg
     4801 tttctgactc cacctgtagc agatcctctg ccacaggaat ccatacccaa atagtgccag
     4861 gagggaggga gcctcccagg agcacagaca ggcctgtgag tgcagataaa accaccactg
     4921 ctgctcagca gaacctgcct ggaaccctca agacacagga accaaggggc tgcctggaac
     4981 aggagtctta cagtctctgt ctgcacccag agctgatcct gtgccacaga gctacatata
     5041 aaaataccgc caagagagag ctggtctccc aggagtgcct acccaactga gagcacaggt
     5101 aaaactacca cttctcttca aattcctggc ccaagacgga cactcacaga gccatcagga
     5161 cacaggaagc aaggatcagc tggggacagg atccttctgg tctctgcact ccagagctta
     5221 ccctgtacca cagctctcca tacccaaatt cctccctgag agaactggtc ccctgggagt
     5281 actgacacac aggcttgcag gagggacaag ccacagtcag agacagcaag accagctaac
     5341 accagagata accagatggt gaaaggcaaa tgcaaaaaat cataagcaat agataccaag
     5401 actacttgac atcatcagaa cccagttctc ccaccacagt gaatcctagt ttccccacac
     5461 accagaaaaa caagactctg gtttaacatc acatctcata atgatgatag aggaatttaa
     5521 aaaggacata aataactccc ttaaagaaat acaagagaac aaagtagaag accttaaaga
     5581 ggaaacacac acacacacaa aacccttaaa gaattacagg agaacacaac caaacaggtg
     5641 aaggaactga acaaaaccat ccaggatcta aaaatggaaa tagaaacaat aaagaaatca
     5701 caaagggaga caattctgga gttagaaaac ccatgacctc ttacataaat aatggtcctt
     5761 attttctaca tcataactga agttttaata agtgaagtca tagtttgctg tctccttcat
     5821 ttgtatatcc tccctcccat aagctttatg tttgaactct cctctaaccc agctctttac
     5881 tctgtgtcct agagccacac atgcaactca agacgtttct ccacttactc ctggactttg
     5941 ctataactat ataatttgta tttcataccc agtcatttct ggttcctcat caccattcaa
     6001 accactgatg aaccttccta aaatcctatt tcatttcaat acatgcctgc acagagtccc
     6061 caaggagctc ctcggcgcct ggataactgc ctactcctag gctagcactg agagaactct
     6121 agaacctgtc ctcagatctg ctcatccgtt catctgctat tttcttcttg aagcaaatgg
     6181 actcagtgac ccttcccaaa gccattccct tccactgcca tgctggagcc cttctctgat
     6241 gtattatact tcttaagaca tctcctctgt gtaaaataaa ggacgtgaca aatgtgtaac
     6301 ccatcacggt ctctctacag acttctttag ctacacatct gtatgctgca tgtgaactac
     6361 atgcatgatg cctggagccc acagatgccc tggcattgga gctacggaac attgtgagca
     6421 ctgtgtgagt gctagaaatc caaccttgct cctctggaag aataattggt gctcttaacc
     6481 actgagccat ctccctatct cctttagact tcttgagcat tctctatcac tctttccctt
     6541 ctatttatcc tggcatatta attacgtaca caaaccgatc cttacttcac ctgtgttagc
     6601 aagaaaaact attttaacac atctgctttt caacttagtt catttttaaa acagaaatat
     6661 aaaactgcta ttgttaagaa gtatttcatg ttggaaatgt ctaaactgtg ttactgtcct
     6721 gtataatccc tcacatctaa atcataaacc ctcaatgaac tcatgactct ttcttgtatt
     6781 ttctcaccat gttagatatt gttataaatc gactgtaaaa tgtctttaaa atattcatca
     6841 tcctggaata aaccatctaa acttat
//
