LOCUS       NM_010706               1099 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus lectin, galactose binding, soluble 4 (Lgals4),
            transcript variant 1, mRNA.
ACCESSION   NM_010706
VERSION     NM_010706.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1099)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1099)
  AUTHORS   Nagasaki,S.C., Fukuda,T.D., Yamada,M., Suzuki,Y.I., Kakutani,R.,
            Guy,A.T. and Imayoshi,I.
  TITLE     Enhancement of Vivid-based photo-activatable Gal4 transcription
            factor in mammalian cells
  JOURNAL   Cell Struct Funct 48 (1), 31-47 (2023)
   PUBMED   36529516
  REMARK    GeneRIF: Enhancement of Vivid-based photo-activatable Gal4
            transcription factor in mammalian cells.
REFERENCE   3  (bases 1 to 1099)
  AUTHORS   Lidstrom,T., Cumming,J., Gaur,R., Frangsmyr,L., Pateras,I.S.,
            Mickert,M.J., Franklin,O., Forsell,M.N.E., Arnberg,N., Dongre,M.,
            Patthey,C. and Ohlund,D.
  TITLE     Extracellular Galectin 4 Drives Immune Evasion and Promotes T-cell
            Apoptosis in Pancreatic Cancer
  JOURNAL   Cancer Immunol Res 11 (1), 72-92 (2023)
   PUBMED   36478037
  REMARK    GeneRIF: Extracellular Galectin 4 Drives Immune Evasion and
            Promotes T-cell Apoptosis in Pancreatic Cancer.
REFERENCE   4  (bases 1 to 1099)
  AUTHORS   Brocca,M.E., Mora-Rubio,A., Alonso-Calvino,E., Fernandez-Lopez,E.,
            Diez-Revuelta,N., Martos-Punal,D., Aguilar,J., Higuero,A.M. and
            Abad-Rodriguez,J.
  TITLE     Normal Cortical Myelination in Galectin-4-Deficient Mice
  JOURNAL   Cells 11 (21), 3485 (2022)
   PUBMED   36359880
  REMARK    GeneRIF: Normal Cortical Myelination in Galectin-4-Deficient Mice.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 1099)
  AUTHORS   Herriges,M.J., Tischfield,D.J., Cui,Z., Morley,M.P., Han,Y.,
            Babu,A., Li,S., Lu,M., Cendan,I., Garcia,B.A., Anderson,S.A. and
            Morrisey,E.E.
  TITLE     The NANCI-Nkx2.1 gene duplex buffers Nkx2.1 expression to maintain
            lung development and homeostasis
  JOURNAL   Genes Dev 31 (9), 889-903 (2017)
   PUBMED   28546511
REFERENCE   6  (bases 1 to 1099)
  AUTHORS   Gitt,M.A., Colnot,C., Poirier,F., Nani,K.J., Barondes,S.H. and
            Leffler,H.
  TITLE     Galectin-4 and galectin-6 are two closely related lectins expressed
            in mouse gastrointestinal tract
  JOURNAL   J Biol Chem 273 (5), 2954-2960 (1998)
   PUBMED   9446608
REFERENCE   7  (bases 1 to 1099)
  AUTHORS   Puche,A.C., Poirier,F., Hair,M., Bartlett,P.F. and Key,B.
  TITLE     Role of galectin-1 in the developing mouse olfactory system
  JOURNAL   Dev Biol 179 (1), 274-287 (1996)
   PUBMED   8873770
REFERENCE   8  (bases 1 to 1099)
  AUTHORS   Nicoll,D.A., Quednau,B.D., Qui,Z., Xia,Y.R., Lusis,A.J. and
            Philipson,K.D.
  TITLE     Cloning of a third mammalian Na+-Ca2+ exchanger, NCX3
  JOURNAL   J Biol Chem 271 (40), 24914-24921 (1996)
   PUBMED   8798769
REFERENCE   9  (bases 1 to 1099)
  AUTHORS   Welch,C.L., Xia,Y.R., Shechter,I., Farese,R., Mehrabian,M.,
            Mehdizadeh,S., Warden,C.H. and Lusis,A.J.
  TITLE     Genetic regulation of cholesterol homeostasis: chromosomal
            organization of candidate genes
  JOURNAL   J Lipid Res 37 (7), 1406-1421 (1996)
   PUBMED   8827514
  REMARK    Erratum:[J Lipid Res 1996 Oct;37(10):2269]
REFERENCE   10 (bases 1 to 1099)
  AUTHORS   Jonassen,T., Marbois,B.N., Kim,L., Chin,A., Xia,Y.R., Lusis,A.J.
            and Clarke,C.F.
  TITLE     Isolation and sequencing of the rat Coq7 gene and the mapping of
            mouse Coq7 to chromosome 7
  JOURNAL   Arch Biochem Biophys 330 (2), 285-289 (1996)
   PUBMED   8660658
  REMARK    Erratum:[Arch Biochem Biophys 1996 Nov 1;335(1):227]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC171210.1.
            
            On Oct 13, 2022 this sequence version replaced NM_010706.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC030297.1, AF510729.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-93                AC171210.1         56327-56419         c
            94-182              AC171210.1         56017-56105         c
            183-387             AC171210.1         54522-54726         c
            388-528             AC171210.1         52797-52937         c
            529-561             AC171210.1         50259-50291         c
            562-600             AC171210.1         50101-50139         c
            601-630             AC171210.1         49943-49972         c
            631-719             AC171210.1         49601-49689         c
            720-882             AC171210.1         49246-49408         c
            883-1099            AC171210.1         48850-49066         c
FEATURES             Location/Qualifiers
     source          1..1099
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 16.94 cM"
     gene            1..1099
                     /gene="Lgals4"
                     /gene_synonym="gal-4"
                     /note="lectin, galactose binding, soluble 4"
                     /db_xref="GeneID:16855"
                     /db_xref="MGI:MGI:107536"
     exon            1..93
                     /gene="Lgals4"
                     /gene_synonym="gal-4"
                     /inference="alignment:Splign:2.1.0"
     exon            94..182
                     /gene="Lgals4"
                     /gene_synonym="gal-4"
                     /inference="alignment:Splign:2.1.0"
     exon            183..387
                     /gene="Lgals4"
                     /gene_synonym="gal-4"
                     /inference="alignment:Splign:2.1.0"
     exon            388..528
                     /gene="Lgals4"
                     /gene_synonym="gal-4"
                     /inference="alignment:Splign:2.1.0"
     exon            529..561
                     /gene="Lgals4"
                     /gene_synonym="gal-4"
                     /inference="alignment:Splign:2.1.0"
     exon            562..600
                     /gene="Lgals4"
                     /gene_synonym="gal-4"
                     /inference="alignment:Splign:2.1.0"
     exon            601..630
                     /gene="Lgals4"
                     /gene_synonym="gal-4"
                     /inference="alignment:Splign:2.1.0"
     exon            631..719
                     /gene="Lgals4"
                     /gene_synonym="gal-4"
                     /inference="alignment:Splign:2.1.0"
     exon            720..882
                     /gene="Lgals4"
                     /gene_synonym="gal-4"
                     /inference="alignment:Splign:2.1.0"
     exon            883..1099
                     /gene="Lgals4"
                     /gene_synonym="gal-4"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1082..1087
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Lgals4"
                     /gene_synonym="gal-4"
                     /note="hexamer: AATAAA"
     polyA_site      1099
                     /gene="Lgals4"
                     /gene_synonym="gal-4"
                     /note="major polyA site"
ORIGIN      
        1 cccacacatc tcttctctcc aggcaagcta tcagcccaga ctctcaagat ggcctatgtt
       61 ccagcaccgg gctaccagcc cacctacaat ccgactctgc cctacaagag acccatccca
      121 ggtggcctca gtgtcgggat gtccgtttac atccaaggaa tggccaaaga gaacatgaga
      181 cggttccacg tgaacttcgc tgtggggcag gatgatgggg cggatgttgc tttccacttc
      241 aatccccgct ttgatggctg ggacaaggtg gtcttcaaca cgatgcaaag tggacaatgg
      301 ggcaaggaag agaagaagaa gagcatgcct ttccagaagg gcaagcactt cgagctggtg
      361 ttcatggtca tgcctgagca ctacaaggtc gtggtgaacg gaaattcctt ctatgaatac
      421 gggcaccggt tacctgtaca gatggtcacc catctgcaag tggatgggga cctggaactt
      481 cagtccatca acttcctcgg aggccaacca gctgcagccc catatccggg agccatgact
      541 attccagctt accctgctgg gagtcctggg tacaaccctc cacagatgaa caccttgcct
      601 gtcatgacag gacccccagt cttcaatccg cgtgtgccat atgtgggggc tctgcagggg
      661 ggccttacag tccgaagaac catcataatc aagggatatg tacttcctac agccaggaac
      721 tttgtcatca acttcaaggt gggatcgtcc ggagacatag ctttacacct aaacccccgc
      781 ataggtgaca gtgtggttcg caacagcttt atgaatggct cttggggcgc tgaagagagg
      841 aaggtggcct acaacccatt tggccctggg cagttctttg atctgtcaat ccgctgcggc
      901 atggatcgat tcaaggtgtt tgccaatggc cagcaccttt tcgacttctc ccatcggttc
      961 caagcattcc aaatggtaga cacgctggag atcaatggtg acatcacctt gtcctacgtc
     1021 cagatctgag ctcctcctgg ggaaggaagc agaaagatcc ccgagttcca tctaagctcc
     1081 taataaaatg ttgaaggag
//
