LOCUS       NM_008495                817 bp    mRNA    linear   ROD 17-SEP-2024
DEFINITION  Mus musculus lectin, galactose binding, soluble 1 (Lgals1), mRNA.
ACCESSION   NM_008495
VERSION     NM_008495.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 817)
  AUTHORS   Butts,J.C., Wu,S.R., Durham,M.A., Dhindsa,R.S., Revelli,J.P.,
            Ljungberg,M.C., Saulnier,O., McLaren,M.E., Taylor,M.D. and
            Zoghbi,H.Y.
  TITLE     A single-cell transcriptomic map of the developing Atoh1 lineage
            identifies neural fate decisions and neuronal diversity in the
            hindbrain
  JOURNAL   Dev Cell 59 (16), 2171-2188 (2024)
   PUBMED   39106860
REFERENCE   2  (bases 1 to 817)
  AUTHORS   Tang,L., Zhang,Y.Y., Liu,W.J., Fu,Q., Zhao,J. and Liu,Y.B.
  TITLE     DNA methylation of promoter region inhibits galectin-1 expression
            in BMSCs of aged mice
  JOURNAL   Am J Physiol Cell Physiol 326 (2), C429-C441 (2024)
   PUBMED   38105757
  REMARK    GeneRIF: DNA methylation of promoter region inhibits galectin-1
            expression in BMSCs of aged mice.
REFERENCE   3  (bases 1 to 817)
  AUTHORS   Takeuchi,T., Oyama,M., Tamura,M., Arata,Y. and Hatanaka,T.
  TITLE     Reduced form of Galectin-1 Suppresses Osteoclastic Differentiation
            of Human Peripheral Blood Mononuclear Cells and Murine RAW264 Cells
            In Vitro
  JOURNAL   Biomolecules 14 (1), 121 (2024)
   PUBMED   38254721
  REMARK    GeneRIF: Reduced form of Galectin-1 Suppresses Osteoclastic
            Differentiation of Human Peripheral Blood Mononuclear Cells and
            Murine RAW264 Cells In Vitro.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 817)
  AUTHORS   Baldwin,T.A., Teuber,J.P., Kuwabara,Y., Subramani,A., Lin,S.J.,
            Kanisicak,O., Vagnozzi,R.J., Zhang,W., Brody,M.J. and
            Molkentin,J.D.
  TITLE     Palmitoylation-dependent regulation of cardiomyocyte Rac1 signaling
            activity and minor effects on cardiac hypertrophy
  JOURNAL   J Biol Chem 299 (12), 105426 (2023)
   PUBMED   37926281
REFERENCE   5  (bases 1 to 817)
  AUTHORS   Queen,R., Crosier,M., Eley,L., Kerwin,J., Turner,J.E., Yu,J.,
            Alqahtani,A., Dhanaseelan,T., Overman,L., Soetjoadi,H., Baldock,R.,
            Coxhead,J., Boczonadi,V., Laude,A., Cockell,S.J., Kane,M.A.,
            Lisgo,S. and Henderson,D.J.
  TITLE     Spatial transcriptomics reveals novel genes during the remodelling
            of the embryonic human arterial valves
  JOURNAL   PLoS Genet 19 (11), e1010777 (2023)
   PUBMED   38011284
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 817)
  AUTHORS   Wells,V. and Mallucci,L.
  TITLE     Molecular expression of the negative growth factor murine
            beta-galactoside binding protein (mGBP)
  JOURNAL   Biochim Biophys Acta 1121 (3), 239-244 (1992)
   PUBMED   1627600
REFERENCE   7  (bases 1 to 817)
  AUTHORS   Poirier,F., Timmons,P.M., Chan,C.T., Guenet,J.L. and Rigby,P.W.
  TITLE     Expression of the L14 lectin during mouse embryogenesis suggests
            multiple roles during pre- and post-implantation development
  JOURNAL   Development 115 (1), 143-155 (1992)
   PUBMED   1638977
REFERENCE   8  (bases 1 to 817)
  AUTHORS   Chiariotti,L., Wells,V., Bruni,C.B. and Mallucci,L.
  TITLE     Structure and expression of the negative growth factor mouse
            beta-galactoside binding protein gene
  JOURNAL   Biochim Biophys Acta 1089 (1), 54-60 (1991)
   PUBMED   2025648
REFERENCE   9  (bases 1 to 817)
  AUTHORS   Wells,V. and Mallucci,L.
  TITLE     Identification of an autocrine negative growth factor: mouse
            beta-galactoside-binding protein is a cytostatic factor and cell
            growth regulator
  JOURNAL   Cell 64 (1), 91-97 (1991)
   PUBMED   1986871
REFERENCE   10 (bases 1 to 817)
  AUTHORS   Cooper,D.N. and Barondes,S.H.
  TITLE     Evidence for export of a muscle lectin from cytosol to
            extracellular matrix and for a novel secretory mechanism
  JOURNAL   J Cell Biol 110 (5), 1681-1691 (1990)
   PUBMED   2335567
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            X66532.1 and BE956470.1.
            
            On Jan 27, 2006 this sequence version replaced NM_008495.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: X66532.1, BY704534.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-530               X66532.1           1-530
            531-817             BE956470.1         1-287               c
FEATURES             Location/Qualifiers
     source          1..817
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="15"
                     /map="15 37.7 cM"
     gene            1..817
                     /gene="Lgals1"
                     /gene_synonym="Gal-1; Galbp; galectin-1; L-14.5; L14;
                     Lect14"
                     /note="lectin, galactose binding, soluble 1"
                     /db_xref="GeneID:16852"
                     /db_xref="MGI:MGI:96777"
     exon            1..80
                     /gene="Lgals1"
                     /gene_synonym="Gal-1; Galbp; galectin-1; L-14.5; L14;
                     Lect14"
                     /inference="alignment:Splign:2.1.0"
     exon            81..160
                     /gene="Lgals1"
                     /gene_synonym="Gal-1; Galbp; galectin-1; L-14.5; L14;
                     Lect14"
                     /inference="alignment:Splign:2.1.0"
     exon            161..332
                     /gene="Lgals1"
                     /gene_synonym="Gal-1; Galbp; galectin-1; L-14.5; L14;
                     Lect14"
                     /inference="alignment:Splign:2.1.0"
     exon            333..800
                     /gene="Lgals1"
                     /gene_synonym="Gal-1; Galbp; galectin-1; L-14.5; L14;
                     Lect14"
                     /inference="alignment:Splign:2.1.0"
     regulatory      502..507
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Lgals1"
                     /gene_synonym="Gal-1; Galbp; galectin-1; L-14.5; L14;
                     Lect14"
                     /note="hexamer: AATAAA"
     polyA_site      531
                     /gene="Lgals1"
                     /gene_synonym="Gal-1; Galbp; galectin-1; L-14.5; L14;
                     Lect14"
                     /note="major polyA site"
ORIGIN      
        1 cgtctctcgg gtggagtctt ctgactgctg gtggagcagg tctcaggaat ctcttcgctt
       61 cagcttcaat catggcctgt ggtctggtcg ccagcaacct gaatctcaaa cctggggaat
      121 gtctcaaagt tcggggagag gtggcctcgg acgccaagag ctttgtgctg aacctgggaa
      181 aagacagcaa caacctgtgc ctacacttca atcctcgctt caatgcccat ggagacgcca
      241 acaccattgt gtgtaacacc aaggaagatg ggacctgggg aaccgaacac cgggaacctg
      301 ccttcccctt ccagcccggg agcatcacag aggtgtgcat cacctttgac caggctgacc
      361 tgaccatcaa gctgccagac ggacatgaat tcaagttccc caaccgcctc aacatggagg
      421 ccatcaacta catggcggcg gatggagact tcaagattaa gtgcgtggcc tttgagtgaa
      481 gccagccagc ctgtagccct caataaaggc agctgcctct gctccccata atccagccct
      541 ttcatgggag agtgtttgtg tgtgtctatg tgaggggccc cgcccaacct ggtccatctt
      601 cacttccatt catgcctcca tgtgttcttg gtctcagtga cctctcttgt gctttccagg
      661 ccaaagagag cccagcacag agagggctta agtgaccaca gagggtgagc cagtgtccca
      721 ctgtgacagg gacagagcag tgggaggtgg atggatgaac agccggaccg catttgtctt
      781 aataaaagcc agaaaccact aaaaaaaaaa aaaaaaa
//
