LOCUS       NM_020517                668 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus lens epithelial protein (Lenep), mRNA.
ACCESSION   NM_020517
VERSION     NM_020517.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 668)
  AUTHORS   Karim,S.A., Johnson,K.J., Griffiths,I.R. and Vouyiouklis,D.A.
  TITLE     A physical map of the genomic region on mouse chromosome 3
            containing the hindshaker (hsh) mutation
  JOURNAL   Genomics 83 (2), 225-230 (2004)
   PUBMED   14706451
REFERENCE   2  (bases 1 to 668)
  AUTHORS   Wen,Y., Sachs,G. and Athmann,C.
  TITLE     A novel lens epithelium gene, LEP503, is highly conserved in
            different vertebrate species and is developmentally regulated in
            postnatal rat lens
  JOURNAL   Exp Eye Res 70 (2), 159-168 (2000)
   PUBMED   10655141
REFERENCE   3  (bases 1 to 668)
  AUTHORS   Wen,Y., Li,G.W., Chen,P. and Bekhor,I.
  TITLE     Lens epithelial cell mRNA. I. Cloning and sequencing of a messenger
            RNA with a basic motif/leucine-rich domain specifically expressed
            in rat lens epithelial cells
  JOURNAL   Exp Eye Res 60 (6), 675-682 (1995)
   PUBMED   7641850
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            EL956268.1 and CK627663.1.
            
            On Nov 20, 2008 this sequence version replaced NM_020517.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CK627663.1, CX729392.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849378
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            NMD candidate          :: translation inferred from conservation
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-40                EL956268.1         13-52
            41-668              CK627663.1         4-631
FEATURES             Location/Qualifiers
     source          1..668
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 39.1 cM"
     gene            1..668
                     /gene="Lenep"
                     /gene_synonym="Lep503"
                     /note="lens epithelial protein"
                     /db_xref="GeneID:57275"
                     /db_xref="MGI:MGI:1930020"
     exon            1..251
                     /gene="Lenep"
                     /gene_synonym="Lep503"
                     /inference="alignment:Splign:2.1.0"
     CDS             12..197
                     /gene="Lenep"
                     /gene_synonym="Lep503"
                     /note="lens epithelial protein 503"
                     /codon_start=1
                     /product="lens epithelial cell protein LEP503"
                     /protein_id="NP_065263.1"
                     /db_xref="CCDS:CCDS38491.1"
                     /db_xref="GeneID:57275"
                     /db_xref="MGI:MGI:1930020"
                     /translation="MRPPTQPLTQALPFSLRDALRGTGLQVPVIKMGTGWEGMYRTLK
                     EVAYILLCCWCIKELLD"
     exon            252..668
                     /gene="Lenep"
                     /gene_synonym="Lep503"
                     /inference="alignment:Splign:2.1.0"
     regulatory      556..561
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Lenep"
                     /gene_synonym="Lep503"
                     /note="hexamer: AATAAA"
     polyA_site      595
                     /gene="Lenep"
                     /gene_synonym="Lep503"
                     /note="major polyA site"
ORIGIN      
        1 ctgctgtcca catgaggcca ccaacgcagc ccctgaccca ggccctgccc ttctctctca
       61 gagatgccct tcgaggcact ggcctccagg tgcctgtcat taaaatgggc acaggttggg
      121 agggcatgta tcgaaccctg aaggaagtcg cctacatcct tctttgttgc tggtgtatca
      181 aggaactgct ggattaatgg tggcagggaa cacctcctgt cacccctgac accaagacct
      241 gcatccctca gccctaagac tcctggagcc agctggcctt caccaaggat gggtcacaaa
      301 gaactgaaga aagaaccacg aaccttgctc tgagctgtcc atccatctga cctgcctcac
      361 cctggggaat ctctcctcag ctcccatctc tgctgtgctc ctggtacgca tgagcttggc
      421 tcagactcca ttgagactac ggcaggatct aatattcctc caaaaattgg cacagtgagc
      481 ccaccaaccc acgtacttga agaactagga atggactgcc cctgaaatgc ctggtaatca
      541 ctccactata aatataataa ataggcctcg aggccaaaaa ttctgaacat tcaaagggga
      601 atgagggcat gtgtgcttgg aaagggctta gagccagaga gcaggaagaa ggacagatct
      661 cgggagta
//
