LOCUS       NM_001081272            3543 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus low density lipoprotein receptor class A domain
            containing 1 (Ldlrad1), mRNA.
ACCESSION   NM_001081272 XM_621633
VERSION     NM_001081272.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3543)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3543)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL645723.11.
            
            On Jun 18, 2019 this sequence version replaced NM_001081272.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN00849374,
                              SAMN00849375 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-441               AL645723.11        109998-110438
            442-567             AL645723.11        113410-113535
            568-705             AL645723.11        115678-115815
            706-834             AL645723.11        117003-117131
            835-3543            AL645723.11        118620-121328
FEATURES             Location/Qualifiers
     source          1..3543
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 50.16 cM"
     gene            1..3543
                     /gene="Ldlrad1"
                     /note="low density lipoprotein receptor class A domain
                     containing 1"
                     /db_xref="GeneID:546840"
                     /db_xref="MGI:MGI:3652166"
     exon            1..441
                     /gene="Ldlrad1"
                     /inference="alignment:Splign:2.1.0"
     CDS             327..983
                     /gene="Ldlrad1"
                     /codon_start=1
                     /product="low-density lipoprotein receptor class A
                     domain-containing protein 1"
                     /protein_id="NP_001074741.1"
                     /db_xref="CCDS:CCDS38830.1"
                     /db_xref="GeneID:546840"
                     /db_xref="MGI:MGI:3652166"
                     /translation="MSVGCERAEFCPACFWFLGQADAESNITTRRKARPGDEGCGPLC
                     CSRRGACLSVGLLLLLAMLAALLAVATILGHPPRTPETHSCVTLANRTGFLCHDRRHC
                     IPAHAVCDGIRTCPHGEDEAESLCRDVPQSLPSFLLTTCGDPDSWIYSDQKCDGVNNC
                     GDCSDELSPVTTCPPCGPGWWRCSPTVFKYCSCVPRDLCRDSVQHCSDWSDEYSCPGP
                     "
     exon            442..567
                     /gene="Ldlrad1"
                     /inference="alignment:Splign:2.1.0"
     exon            568..705
                     /gene="Ldlrad1"
                     /inference="alignment:Splign:2.1.0"
     exon            706..834
                     /gene="Ldlrad1"
                     /inference="alignment:Splign:2.1.0"
     exon            835..3543
                     /gene="Ldlrad1"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      1133
                     /gene="Ldlrad1"
     regulatory      3523..3528
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ldlrad1"
                     /note="hexamer: ATTACA"
     polyA_site      3543
                     /gene="Ldlrad1"
                     /note="major polyA site"
ORIGIN      
        1 attccacctc agttcctgga gatgagtgtt ggaaccatga acaaagtctt cccccaggta
       61 aaagctgcct gggtctgaac tgactcttga cctagggagc cattctgcag atggaaaggg
      121 cttgtgggag gggaccctag gacccacggc cacatccatc tgccctgggg actcgctcca
      181 cctgagatcc atgagtactg agaagcagca caggacacct aggggtgtta gggcactgtc
      241 actaggagga cctgcctgag tcagtttgga ggacaaagga ggaatgggtc ctgtacgggt
      301 cgaaatgtgg aaatgtgaag cccaggatga gcgtgggctg tgagagagca gaattttgcc
      361 cagcctgctt ctggtttctt ggccaggcag atgccgagag taacatcacc actagaagga
      421 aagcccgccc tggagatgaa ggctgtggtc cactctgctg ctcacgccgt ggagcctgcc
      481 tctcggtcgg cctgctgctc ctgctggcca tgctcgctgc cttgcttgct gtggccacca
      541 tcctcggaca tccaccccgc acaccagaga ctcactcctg cgtgacacta gccaacagga
      601 cagggttctt gtgccacgac cgaaggcact gcatcccagc ccatgctgtg tgcgatggca
      661 tccgcacctg tcctcatggt gaggacgagg ctgagagcct gtgccgagat gtgccccaga
      721 gcctccccag cttcctcctg accacctgtg gagacccaga ctcctggatc tactcagacc
      781 agaaatgtga tggcgtcaac aactgtggag actgctcaga tgagctgagc ccagtgacta
      841 cgtgcccgcc ctgtggccct gggtggtggc gctgctcgcc aactgtgttc aagtactgca
      901 gctgtgtccc gagggatctg tgccgggaca gcgtgcagca ctgctctgac tggtcagatg
      961 agtactcctg tcctggaccc tgagtgagcc tccctccata gcatggaagc tgacacccag
     1021 atcctttcac cagagcacca aaccctggac cgcaagggtg ggaagaaact tttgccatct
     1081 cccagtggta ccggcccctg ttgtctctga acaggaattg tctttcctct tttcaagtgt
     1141 ctcagcctcc acttgagcac gtcaatgaca gggagctcac caccatgtta ggcactctaa
     1201 taagacgagg tgtctgactc catcacttta ggcctgtcta tggcatcaca tagaggagac
     1261 atgctctttg actccagagc aggcctgaat ttccgatctt gtcatccctt gaagagacag
     1321 ataaatgtgt ggcttaaatg ccaagtgagt ttagccccat ggggtagaaa acaaggcaca
     1381 cacatttccc gtcattcccc acctaaggca gaaactgctg agttcaaggc cgttgtaact
     1441 tgttgctcaa ctccccagca gcctcgactg atcacatgag gttgcatatg gcacttggga
     1501 cctagtatct ttctagtttc ccagtctctt ggaggcttgc ggctatagaa tagaagaccc
     1561 agagaaagca cagcttagaa gaacccctca atgcttttag cctgagcctc agccctgctt
     1621 caccccacag tcacctgcag gtttatattt tggtcctgaa gccagaacgc cattcccctg
     1681 cgtcccttgt atcccttcta tcttcctaac acccaggcag gcaaggatag gggttctcat
     1741 tagacagatg gggaaaccga ggcccagggg atgactcgcc cagggtggac cctgtgaggt
     1801 ttgaaaatgg catccaagga gcagccaggc cctggccatt catttgttct ttcaccactt
     1861 gtgtatttct tcacccattt ctgagctgaa ctgagctgag ctgagctggg agctgagggg
     1921 tggagcttgg gggaatgggc ccctagagaa gaggcctggg tcctggcaca tgagcagtag
     1981 ggggtcttat agagagccca cctcacgcca tgtaaggatg agtgagacag tagaactgtg
     2041 gggtcccctt aaggggatgg tcagtctcag caatccctct tcagttgggt ttctttgtag
     2101 aaggtggggg ctcttttcag gaggagggca ttcatgcttg gcccatatga gacatgtaac
     2161 agttctgatt aagccatggg ttattcagta ggtgggaggg gccaaagcat gggtatatgc
     2221 aggaactgaa gatcctcact tcatagtaag agtgctggaa actcagaata gccaaagcaa
     2281 accagtttat tttgtgacct tgcaaggcaa cagcttagaa aggcaggttc gcctagggag
     2341 tacagagggt atttataaac cctaatgcat gcgcctcccc gatcttgtga gtgaccagga
     2401 gggcacaacc ttacaggcac tgaggactcc tctgtccttt atatttgtgt gtgttcatct
     2461 gttttatatc ctgtgtattt caaggcttct cagatgcagg caagcttggc tctgagtaat
     2521 tttctcgtct caaattttag tatggatagg ggtgtagctc agcaaactgt gggtcggggt
     2581 aggcagagtg gtaggcattc attagcagag agccagtgtt ctctgttcag ctttcactgg
     2641 gactaagttg gctcaaggaa ccttcaaaaa tgaatcatca aacttctctt ataaggtgtg
     2701 tgtgtgtgtc aggggcacag tagtggggag agagtaaatc aatacaggta gcaagaatca
     2761 atacaggtag caagaatcaa tacaggtagc aagaatcaat acaggtagca agaatcaatc
     2821 aatacaggta gcaagaatca atacaggtag caagaatcaa tacaggtagc aagaatcaat
     2881 ataagtagca tctcactagt tcatcccgct ggcagtggcc agtgagggag ccatcaggga
     2941 aattaagccc ggaaagtgga ctgttttgtt ttcttttttt ctttttttaa gatttatcta
     3001 ttttatttac atgagtacac tgtagctgtc ttcaaacaca catcagaaga gggcatcaga
     3061 ccccaggatt gtcaggagga aacaatctcc tggggcttgc cctctgctga catgtatgtt
     3121 cacacatgca cacaaaaata aatggaaacg gctggtgaga tggctcggcg gttaagagca
     3181 ctgactgctc ttcctgaggt catgagttca aatcccagcg accacttagt ggctcacaac
     3241 catatgtaat gaggaaacaa gcaaacaaaa ccctataggc ttgagcaagt gggacgggag
     3301 caagagggag aaggaaaggg gagaaaaata aatggaaata taaataaaat aaataaggtg
     3361 aagaatggtt gatggagaca cccggtgtca actttcagcc tccatgtgca cactcaaaat
     3421 agggcaacaa tcttactggc taataaataa ggatgatggg gctgggcaaa tggctcaatg
     3481 ggtaaaagtg cttcttgtga aagcatgaag acttgagttt gaattacaag aacccatgta
     3541 aaa
//
