LOCUS       NM_033175                565 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus late cornified envelope 3C (Lce3c), mRNA.
ACCESSION   NM_033175
VERSION     NM_033175.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 565)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 565)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 565)
  AUTHORS   Roth,W., Kumar,V., Beer,H.D., Richter,M., Wohlenberg,C., Reuter,U.,
            Thiering,S., Staratschek-Jox,A., Hofmann,A., Kreusch,F.,
            Schultze,J.L., Vogl,T., Roth,J., Reichelt,J., Hausser,I. and
            Magin,T.M.
  TITLE     Keratin 1 maintains skin integrity and participates in an
            inflammatory network in skin through interleukin-18
  JOURNAL   J Cell Sci 125 (Pt 22), 5269-5279 (2012)
   PUBMED   23132931
REFERENCE   4  (bases 1 to 565)
  AUTHORS   Fessing,M.Y., Mardaryev,A.N., Gdula,M.R., Sharov,A.A.,
            Sharova,T.Y., Rapisarda,V., Gordon,K.B., Smorodchenko,A.D.,
            Poterlowicz,K., Ferone,G., Kohwi,Y., Missero,C.,
            Kohwi-Shigematsu,T. and Botchkarev,V.A.
  TITLE     p63 regulates Satb1 to control tissue-specific chromatin remodeling
            during development of the epidermis
  JOURNAL   J Cell Biol 194 (6), 825-839 (2011)
   PUBMED   21930775
REFERENCE   5  (bases 1 to 565)
  AUTHORS   Brown,S.J., Tilli,C.M., Jackson,B., Avilion,A.A., MacLeod,M.C.,
            Maltais,L.J., Lovering,R.C. and Byrne,C.
  TITLE     Rodent Lce gene clusters; new nomenclature, gene organization, and
            divergence of human and rodent genes
  JOURNAL   J Invest Dermatol 127 (7), 1782-1786 (2007)
   PUBMED   17410201
REFERENCE   6  (bases 1 to 565)
  AUTHORS   Jonker,L., Kist,R., Aw,A., Wappler,I. and Peters,H.
  TITLE     Pax9 is required for filiform papilla development and suppresses
            skin-specific differentiation of the mammalian tongue epithelium
  JOURNAL   Mech Dev 121 (11), 1313-1322 (2004)
   PUBMED   15454262
REFERENCE   7  (bases 1 to 565)
  AUTHORS   Marshall,D., Hardman,M.J., Nield,K.M. and Byrne,C.
  TITLE     Differentially expressed late constituents of the epidermal
            cornified envelope
  JOURNAL   Proc Natl Acad Sci U S A 98 (23), 13031-13036 (2001)
   PUBMED   11698679
REFERENCE   8  (bases 1 to 565)
  AUTHORS   Wang,A., Johnson,D.G. and MacLeod,M.C.
  TITLE     Molecular cloning and characterization of a novel mouse epidermal
            differentiation gene and its promoter
  JOURNAL   Genomics 73 (3), 284-290 (2001)
   PUBMED   11350120
REFERENCE   9  (bases 1 to 565)
  AUTHORS   Wang,X., Al-Dhalimy,M., Lagasse,E., Finegold,M. and Grompe,M.
  TITLE     Liver repopulation and correction of metabolic liver disease by
            transplanted adult mouse pancreatic cells
  JOURNAL   Am J Pathol 158 (2), 571-579 (2001)
   PUBMED   11159194
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC132274.3.
            
            On Mar 18, 2022 this sequence version replaced NM_033175.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: EH107232.1, AK009036.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849376, SAMN00849383
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-50                AC132274.3         58372-58421         c
            51-565              AC132274.3         57176-57690         c
FEATURES             Location/Qualifiers
     source          1..565
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 40.14 cM"
     gene            1..565
                     /gene="Lce3c"
                     /gene_synonym="2300007B01Rik; Eig3; Sprrl1"
                     /note="late cornified envelope 3C"
                     /db_xref="GeneID:94060"
                     /db_xref="MGI:MGI:2135932"
     exon            1..50
                     /gene="Lce3c"
                     /gene_synonym="2300007B01Rik; Eig3; Sprrl1"
                     /inference="alignment:Splign:2.1.0"
     exon            51..565
                     /gene="Lce3c"
                     /gene_synonym="2300007B01Rik; Eig3; Sprrl1"
                     /inference="alignment:Splign:2.1.0"
     CDS             68..364
                     /gene="Lce3c"
                     /gene_synonym="2300007B01Rik; Eig3; Sprrl1"
                     /note="small proline rich-like 1"
                     /codon_start=1
                     /product="late cornified envelope 3C"
                     /protein_id="NP_149410.1"
                     /db_xref="CCDS:CCDS38521.1"
                     /db_xref="GeneID:94060"
                     /db_xref="MGI:MGI:2135932"
                     /translation="MSCQQSQKQCQPPPKCPSPKCSPKCPPKSTAQCLPAASSCCATS
                     SGGCSLPSSEGGCCLSHHRRRSHRCRRRSSSSCDRGSGQQSGGSGCGHSSGGCC"
     regulatory      544..549
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Lce3c"
                     /gene_synonym="2300007B01Rik; Eig3; Sprrl1"
                     /note="hexamer: AATAAA"
     polyA_site      565
                     /gene="Lce3c"
                     /gene_synonym="2300007B01Rik; Eig3; Sprrl1"
                     /note="major polyA site"
ORIGIN      
        1 agccacagcc tcttcagcac agccttcttc tcctgccttt gctgtatctg gtccagttcc
       61 tgccgagatg tcctgccagc agagccagaa gcagtgccag cctcctccca agtgtccctc
      121 tccaaagtgc tccccaaagt gccccccaaa gagcacagca cagtgtctgc ctgcagcctc
      181 ttcctgctgt gctacaagct ctgggggctg cagtctcccc agctctgagg gaggctgctg
      241 cctgagccac cacaggcgca ggtcccacag atgcaggcgc aggagctcca gttcctgtga
      301 ccgtggcagt ggtcagcagt ctgggggctc aggctgtggc cacagctctg ggggctgctg
      361 ctgacctgga gcatgatgct gagacaagac agtctggagg aatcagcatc ccaggggtca
      421 agaaaagccc agctagtctt gttttatctg atcctggaga gtcttctctg cctgtctgat
      481 gctcactgcc cttgttccct tccttcctgt ggaatgcatg tgcccatcct tggttttgac
      541 tagaataaag attctatccc cacca
//
