LOCUS       NM_025501                562 bp    mRNA    linear   ROD 07-AUG-2023
DEFINITION  Mus musculus late cornified envelope 3B (Lce3b), mRNA.
ACCESSION   NM_025501
VERSION     NM_025501.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 562)
  AUTHORS   Kumar V, Bouameur JE, Bar J, Rice RH, Hornig-Do HT, Roop DR,
            Schwarz N, Brodesser S, Thiering S, Leube RE, Wiesner RJ, Vijayaraj
            P, Brazel CB, Heller S, Binder H, Loffler-Wirth H, Seibel P and
            Magin TM.
  TITLE     A keratin scaffold regulates epidermal barrier formation,
            mitochondrial lipid composition, and activity
  JOURNAL   J Cell Biol 211 (5), 1057-1075 (2015)
   PUBMED   26644517
  REMARK    Erratum:[J Cell Biol. 2016 Mar 28;212(7):877. PMID: 27002167]
REFERENCE   2  (bases 1 to 562)
  AUTHORS   Krishnaswami SR, Kumar S, Ordoukhanian P and Yu BD.
  TITLE     Fate and plasticity of the epidermis in response to congenital
            activation of BRAF
  JOURNAL   J Invest Dermatol 135 (2), 481-489 (2015)
   PUBMED   25202828
REFERENCE   3  (bases 1 to 562)
  AUTHORS   Gunschmann C, Stachelscheid H, Akyuz MD, Schmitz A, Missero C,
            Bruning JC and Niessen CM.
  TITLE     Insulin/IGF-1 controls epidermal morphogenesis via regulation of
            FoxO-mediated p63 inhibition
  JOURNAL   Dev Cell 26 (2), 176-187 (2013)
   PUBMED   23906066
REFERENCE   4  (bases 1 to 562)
  AUTHORS   Brown,S.J., Tilli,C.M., Jackson,B., Avilion,A.A., MacLeod,M.C.,
            Maltais,L.J., Lovering,R.C. and Byrne,C.
  TITLE     Rodent Lce gene clusters; new nomenclature, gene organization, and
            divergence of human and rodent genes
  JOURNAL   J Invest Dermatol 127 (7), 1782-1786 (2007)
   PUBMED   17410201
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC132274.3.
            
            On Mar 18, 2022 this sequence version replaced NM_025501.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC059084.1, AK009201.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849376, SAMN00849380
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-44                AC132274.3         69885-69928         c
            45-562              AC132274.3         68810-69327         c
FEATURES             Location/Qualifiers
     source          1..562
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 40.14 cM"
     gene            1..562
                     /gene="Lce3b"
                     /gene_synonym="2310007F04Rik; Sprrl6A"
                     /note="late cornified envelope 3B"
                     /db_xref="GeneID:66344"
                     /db_xref="MGI:MGI:1913594"
     exon            1..44
                     /gene="Lce3b"
                     /gene_synonym="2310007F04Rik; Sprrl6A"
                     /inference="alignment:Splign:2.1.0"
     exon            45..562
                     /gene="Lce3b"
                     /gene_synonym="2310007F04Rik; Sprrl6A"
                     /inference="alignment:Splign:2.1.0"
     CDS             65..361
                     /gene="Lce3b"
                     /gene_synonym="2310007F04Rik; Sprrl6A"
                     /codon_start=1
                     /product="late cornified envelope protein 3C"
                     /protein_id="NP_079777.1"
                     /db_xref="CCDS:CCDS38520.1"
                     /db_xref="GeneID:66344"
                     /db_xref="MGI:MGI:1913594"
                     /translation="MSCQQSQKQCQPPPKCPSPKCSPKCPRKSTAQCLPAASSCCATN
                     SGGCSLPRSEGGCCLSHHRRRSHRCRRRSSSSCDRGSGQQSGGSGCGHSSGDCC"
ORIGIN      
        1 gccaaagcat cctcagacac ggacttctgt ctcctttgaa tctagtcaac tgactcctgc
       61 caagatgtcc tgccagcaga gccagaagca gtgccaacct cctcccaagt gtccctctcc
      121 aaagtgctcc ccaaagtgcc ccaggaagag cacagcacag tgtctgcctg cagcctcttc
      181 ctgctgtgct acaaactctg ggggctgcag tctccccaga tctgagggag gctgctgcct
      241 gagccaccac aggcgcaggt cccacagatg caggcgcagg agctccagtt cctgtgaccg
      301 tggcagtggt cagcagtctg gggggtcagg ctgtggccac agctctgggg actgctgctg
      361 acctggagca tgatgtggag acaagacagt ctggaggaat caacatccca ggggtcaaga
      421 aaagcccagc tagtcttgtt ttgtctgatc ctggacaccc ttctctgatt gtctgatgtt
      481 cacagccctt gttcccaccc ttcctgtgga atgcatgtgc ccatccttgg ttctgactag
      541 aataaagatt ctatccccac ca
//
