LOCUS       NM_028625                715 bp    mRNA    linear   ROD 04-AUG-2023
DEFINITION  Mus musculus late cornified envelope 1A2 (Lce1a2), mRNA.
ACCESSION   NM_028625
VERSION     NM_028625.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 715)
  AUTHORS   Miyai M, Hamada M, Moriguchi T, Hiruma J, Kamitani-Kawamoto A,
            Watanabe H, Hara-Chikuma M, Takahashi K, Takahashi S and Kataoka K.
  TITLE     Transcription Factor MafB Coordinates Epidermal Keratinocyte
            Differentiation
  JOURNAL   J Invest Dermatol 136 (9), 1848-1857 (2016)
   PUBMED   27208706
  REMARK    Review article
REFERENCE   2  (bases 1 to 715)
  AUTHORS   Krishnaswami SR, Kumar S, Ordoukhanian P and Yu BD.
  TITLE     Fate and plasticity of the epidermis in response to congenital
            activation of BRAF
  JOURNAL   J Invest Dermatol 135 (2), 481-489 (2015)
   PUBMED   25202828
REFERENCE   3  (bases 1 to 715)
  AUTHORS   Nagarajan P, Chin SS, Wang D, Liu S, Sinha S and Garrett-Sinha LA.
  TITLE     Ets1 blocks terminal differentiation of keratinocytes and induces
            expression of matrix metalloproteases and innate immune mediators
  JOURNAL   J Cell Sci 123 (Pt 20), 3566-3575 (2010)
   PUBMED   20930145
REFERENCE   4  (bases 1 to 715)
  AUTHORS   Ezhkova E, Pasolli HA, Parker JS, Stokes N, Su IH, Hannon G,
            Tarakhovsky A and Fuchs E.
  TITLE     Ezh2 orchestrates gene expression for the stepwise differentiation
            of tissue-specific stem cells
  JOURNAL   Cell 136 (6), 1122-1135 (2009)
   PUBMED   19303854
REFERENCE   5  (bases 1 to 715)
  AUTHORS   Brown,S.J., Tilli,C.M., Jackson,B., Avilion,A.A., MacLeod,M.C.,
            Maltais,L.J., Lovering,R.C. and Byrne,C.
  TITLE     Rodent Lce gene clusters; new nomenclature, gene organization, and
            divergence of human and rodent genes
  JOURNAL   J Invest Dermatol 127 (7), 1782-1786 (2007)
   PUBMED   17410201
REFERENCE   6  (bases 1 to 715)
  AUTHORS   Matsui T, Hayashi-Kisumi F, Kinoshita Y, Katahira S, Morita K,
            Miyachi Y, Ono Y, Imai T, Tanigawa Y, Komiya T and Tsukita S.
  TITLE     Identification of novel keratinocyte-secreted peptides
            dermokine-alpha/-beta and a new stratified epithelium-secreted
            protein gene complex on human chromosome 19q13.1
  JOURNAL   Genomics 84 (2), 384-397 (2004)
   PUBMED   15234001
REFERENCE   7  (bases 1 to 715)
  AUTHORS   Marshall D, Hardman MJ, Nield KM and Byrne C.
  TITLE     Differentially expressed late constituents of the epidermal
            cornified envelope
  JOURNAL   Proc Natl Acad Sci U S A 98 (23), 13031-13036 (2001)
   PUBMED   11698679
REFERENCE   8  (bases 1 to 715)
  AUTHORS   Suzuki H, Fukunishi Y, Kagawa I, Saito R, Oda H, Endo T, Kondo S,
            Bono H, Okazaki Y and Hayashizaki Y.
  TITLE     Protein-protein interaction panel using mouse full-length cDNAs
  JOURNAL   Genome Res 11 (10), 1758-1765 (2001)
   PUBMED   11591653
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK003412.1.
            
            On Sep 21, 2006 this sequence version replaced NM_028625.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK003412.1, BC100540.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849376
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-715               AK003412.1         2-716
FEATURES             Location/Qualifiers
     source          1..715
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 40.14 cM"
     gene            1..715
                     /gene="Lce1a2"
                     /gene_synonym="1110004E04Rik; Sprrl2"
                     /note="late cornified envelope 1A2"
                     /db_xref="GeneID:73722"
                     /db_xref="MGI:MGI:1920972"
     exon            1..51
                     /gene="Lce1a2"
                     /gene_synonym="1110004E04Rik; Sprrl2"
                     /inference="alignment:Splign:2.1.0"
     exon            52..715
                     /gene="Lce1a2"
                     /gene_synonym="1110004E04Rik; Sprrl2"
                     /inference="alignment:Splign:2.1.0"
     CDS             75..524
                     /gene="Lce1a2"
                     /gene_synonym="1110004E04Rik; Sprrl2"
                     /note="small proline rich-like 2"
                     /codon_start=1
                     /product="late cornified envelope 1A2"
                     /protein_id="NP_082901.1"
                     /db_xref="CCDS:CCDS17564.1"
                     /db_xref="GeneID:73722"
                     /db_xref="MGI:MGI:1920972"
                     /translation="MSCQQNQQQCQPPPKCPPKCQTPKCPPKCPPKCPPKCPPVSSCC
                     SLGSGGCCGSSSGGCCSSGGCCSSGGCCSSGGGGCCLSHHRPRRSLRRHRHSSGCCSS
                     GGSSGCCGSSGGSGGCCGSSGGSSGCCGSSGGSSGCCGSSQQSGGCC"
     regulatory      690..695
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Lce1a2"
                     /gene_synonym="1110004E04Rik; Sprrl2"
                     /note="putative"
ORIGIN      
        1 attcatacac atcctgaggt gcccaaggat cttgtactgc ctgtcatctt gccccagagc
       61 attcaccagc agagatgtcc tgccagcaga accagcagca gtgtcagccc cctcccaagt
      121 gtcctcccaa gtgccagacc ccaaaatgcc ctccaaaatg cccccctaag tgtcctccca
      181 agtgcccccc tgtgtcttcc tgctgtagcc tgggttctgg gggttgctgt ggctccagct
      241 ctgggggctg ttgcagctct ggaggctgct gcagctctgg tggctgctgc agctctgggg
      301 gtggaggctg ctgcctgagc caccacagac ctcgcagatc cctccgtcgc catcgccata
      361 gctctggatg ttgtagcagt ggtggcagca gtggatgctg tggcagcagt ggtggcagtg
      421 gtggctgctg tggaagcagt ggtggcagca gtggatgctg tggcagcagt ggtggcagca
      481 gtggctgctg tggcagtagc cagcagtctg ggggctgctg ctgacctgag caactaacac
      541 tttagacttc cattcaggag gaagccatgt tcagtggacc ctccctggcc tgctcttctc
      601 tcctgctgct ctctgtgtcc tgggctcaaa gatgctgtag tcttgtgaga tgtccccttt
      661 tgaaggacct gtattctcag ggacaaagta ataaagtgct tctctcacaa tcttc
//
