LOCUS       NM_028451               6617 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus La ribonucleoprotein 1, translational regulator
            (Larp1), mRNA.
ACCESSION   NM_028451 XM_126172 XM_905029
VERSION     NM_028451.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6617)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 6617)
  AUTHORS   Farooq,Z., Kusuma,F., Burke,P., Dufour,C.R., Lee,D., Tabatabaei,N.,
            Toboz,P., Radovani,E., Greenblatt,J.F., Rehman,J., Class,J.,
            Khoutorsky,A., Fonseca,B.D., Richner,J.M., Mercier,E., Bourque,G.,
            Giguere,V., Subramaniam,A.R., Han,J. and Tahmasebi,S.
  TITLE     The amino acid sensor GCN2 suppresses terminal oligopyrimidine
            (TOP) mRNA translation via La-related protein 1 (LARP1)
  JOURNAL   J Biol Chem 298 (9), 102277 (2022)
   PUBMED   35863436
  REMARK    GeneRIF: The amino acid sensor GCN2 suppresses terminal
            oligopyrimidine (TOP) mRNA translation via La-related protein 1
            (LARP1).
REFERENCE   3  (bases 1 to 6617)
  AUTHORS   Yonezu,Y., Tanabe,S., Misawa,H. and Muramatsu,R.
  TITLE     Lysophosphatidic acid stimulates pericyte migration via LPA
            receptor 1
  JOURNAL   Biochem Biophys Res Commun 618, 61-66 (2022)
   PUBMED   35716596
  REMARK    GeneRIF: Lysophosphatidic acid stimulates pericyte migration via
            LPA receptor 1.
REFERENCE   4  (bases 1 to 6617)
  AUTHORS   Werneck-de-Castro,J.P., Pecanha,F.L.M., Silvestre,D.H. and
            Bernal-Mizrachi,E.
  TITLE     The RNA-binding protein LARP1 is dispensable for pancreatic
            beta-cell function and mass
  JOURNAL   Sci Rep 11 (1), 2079 (2021)
   PUBMED   33483593
  REMARK    GeneRIF: The RNA-binding protein LARP1 is dispensable for
            pancreatic beta-cell function and mass.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 6617)
  AUTHORS   Vincentz,J.W., Firulli,B.A., Toolan,K.P., Arking,D.E.,
            Sotoodehnia,N., Wan,J., Chen,P.S., de Gier-de Vries,C.,
            Christoffels,V.M., Rubart-von der Lohe,M. and Firulli,A.B.
  TITLE     Variation in a Left Ventricle-Specific Hand1 Enhancer Impairs GATA
            Transcription Factor Binding and Disrupts Conduction System
            Development and Function
  JOURNAL   Circ Res 125 (6), 575-589 (2019)
   PUBMED   31366290
REFERENCE   6  (bases 1 to 6617)
  AUTHORS   Cobellis,G., Nicolaus,G., Iovino,M., Romito,A., Marra,E.,
            Barbarisi,M., Sardiello,M., Di Giorgio,F.P., Iovino,N., Zollo,M.,
            Ballabio,A. and Cortese,R.
  TITLE     Tagging genes with cassette-exchange sites
  JOURNAL   Nucleic Acids Res 33 (4), e44 (2005)
   PUBMED   15741177
  REMARK    Publication Status: Online-Only
REFERENCE   7  (bases 1 to 6617)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Koseki,H., Hiraoka,S.,
            Saga,Y., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: III. the complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (4), 167-180 (2003)
   PUBMED   14621295
REFERENCE   8  (bases 1 to 6617)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   9  (bases 1 to 6617)
  AUTHORS   Chauvet,S., Maurel-Zaffran,C., Miassod,R., Jullien,N., Pradel,J.
            and Aragnol,D.
  TITLE     dlarp, a new candidate Hox target in Drosophila whose orthologue in
            mouse is expressed at sites of epithelium/mesenchymal interactions
  JOURNAL   Dev Dyn 218 (3), 401-413 (2000)
   PUBMED   10878606
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL672182.18.
            
            On or before Apr 10, 2009 this sequence version replaced
            XM_905029.2, XM_126172.8.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR11927934.318210.1,
                                           SRR10662773.2280509.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-484               AL672182.18        160545-161028       c
            485-546             AL672182.18        129640-129701       c
            547-612             AL672182.18        129337-129402       c
            613-787             AL672182.18        128440-128614       c
            788-916             AL672182.18        127734-127862       c
            917-1123            AL672182.18        127450-127656       c
            1124-1286           AL672182.18        127186-127348       c
            1287-1431           AL672182.18        126042-126186       c
            1432-1606           AL672182.18        122223-122397       c
            1607-1776           AL672182.18        121946-122115       c
            1777-2169           AL672182.18        120003-120395       c
            2170-2293           AL672182.18        119186-119309       c
            2294-2499           AL672182.18        118885-119090       c
            2500-2606           AL672182.18        118361-118467       c
            2607-2758           AL672182.18        117361-117512       c
            2759-2903           AL672182.18        114481-114625       c
            2904-3013           AL672182.18        112929-113038       c
            3014-3141           AL672182.18        112704-112831       c
            3142-6617           AL672182.18        108058-111533       c
FEATURES             Location/Qualifiers
     source          1..6617
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 35.55 cM"
     gene            1..6617
                     /gene="Larp1"
                     /gene_synonym="1810024J12Rik; 3110040D16Rik; Larp;
                     mKIAA0731"
                     /note="La ribonucleoprotein 1, translational regulator"
                     /db_xref="GeneID:73158"
                     /db_xref="MGI:MGI:1890165"
     exon            1..484
                     /gene="Larp1"
                     /gene_synonym="1810024J12Rik; 3110040D16Rik; Larp;
                     mKIAA0731"
                     /inference="alignment:Splign:2.1.0"
     CDS             130..3348
                     /gene="Larp1"
                     /gene_synonym="1810024J12Rik; 3110040D16Rik; Larp;
                     mKIAA0731"
                     /note="la related protein; La ribonucleoprotein domain
                     family, member 1"
                     /codon_start=1
                     /product="la-related protein 1"
                     /protein_id="NP_082727.1"
                     /db_xref="CCDS:CCDS56771.1"
                     /db_xref="GeneID:73158"
                     /db_xref="MGI:MGI:1890165"
                     /translation="MATQVEPLLPAGAPLLQAEEHGLARKKPAPDAQAESGPGDGGGE
                     PDGGVRRPRPACARPGRDGAERESPRPPAAAEAPAGSDGEDGGRRDFVEAPPPKVNPW
                     TKHAPPPAAVNGQPPPEPSAPAKVVRAAAPKPRKGSKVGDFGDAVNWPTPGEIAHKSV
                     QPQSHKPQPARKLPPKKDMKEQEKGDGSDSKESPKTKSDESGEEKNGDEDCQRGGQKK
                     KGSKHKWVPLQIDMKPEVPREKLASRPTRPQEPRHTPAVRGEMKGSEPATYMPVSVAP
                     PTPAWQPETKVEPAWHDQDETSSVKSDGAGGARASFRGRGRGRGRGRGRGRGGTRTHF
                     DYQFGYRKFDGTEGPRTHKYMNNITYYFDNVSSNEIYSMDQELLKDYIKRQIEYYFSV
                     DNLERDFFLRRKMDADGFLPITLIASFHRVQALTTDISLIFAALKDSKVVEMVEEKVR
                     RREEPEKWPLPGPPIVDYSQTDFSQLLNCPEFVPRQHYQKETESAPGSPRAVTPVPTK
                     TEEVSNLKTLPKGLSASLPDLDSESWIEVKKRPRPSPARPKKPEEPRFSHPTALPQQL
                     PSQQLMSKDQDEQEELDFLFDEEMEQMDGRKNTFTAWSEEDSDYEIDDRDVNKILIVT
                     QTPPYMRRHPGGDRTGNHTSRAKMSAELAKVINDGLFYYEQDLWTEKFEPEYSQIKQE
                     VENFKKVNMISREQFDTLTPEPPVDPNQEVPPGPPRFQQVPTDALANKLFGAPEPSTI
                     ARSLPTTVPESPNYRNARTPRTPRTPQLKDSSQTPRFYPVVKEGRTLDAKMPRKRKTR
                     HSSNPPLESHVGWVMDSREHRPRTASISSSPSEGTPAVGSYGCTPQSLPKFQHPSHEL
                     LKENGFTQHVYHKYRRRCLNERKRLGIGQSQEMNTLFRFWSFFLRDHFNKKMYEEFKQ
                     LALEDAKEGYRYGLECLFRYYSYGLEKKFRLDIFKDFQEETVKDYEAGQLYGLEKFWA
                     FLKYSKAKNLDIDPKLQEYLGKFRRLEDFRVDPPMGEEGNHKRHPVVAGGSGEGRKRC
                     PSQSSSRPATGISQPPTTPTGQATREDAKWTSQHSDTLTLRK"
     exon            485..546
                     /gene="Larp1"
                     /gene_synonym="1810024J12Rik; 3110040D16Rik; Larp;
                     mKIAA0731"
                     /inference="alignment:Splign:2.1.0"
     exon            547..612
                     /gene="Larp1"
                     /gene_synonym="1810024J12Rik; 3110040D16Rik; Larp;
                     mKIAA0731"
                     /inference="alignment:Splign:2.1.0"
     exon            613..787
                     /gene="Larp1"
                     /gene_synonym="1810024J12Rik; 3110040D16Rik; Larp;
                     mKIAA0731"
                     /inference="alignment:Splign:2.1.0"
     exon            788..916
                     /gene="Larp1"
                     /gene_synonym="1810024J12Rik; 3110040D16Rik; Larp;
                     mKIAA0731"
                     /inference="alignment:Splign:2.1.0"
     exon            917..1123
                     /gene="Larp1"
                     /gene_synonym="1810024J12Rik; 3110040D16Rik; Larp;
                     mKIAA0731"
                     /inference="alignment:Splign:2.1.0"
     exon            1124..1286
                     /gene="Larp1"
                     /gene_synonym="1810024J12Rik; 3110040D16Rik; Larp;
                     mKIAA0731"
                     /inference="alignment:Splign:2.1.0"
     exon            1287..1431
                     /gene="Larp1"
                     /gene_synonym="1810024J12Rik; 3110040D16Rik; Larp;
                     mKIAA0731"
                     /inference="alignment:Splign:2.1.0"
     exon            1432..1606
                     /gene="Larp1"
                     /gene_synonym="1810024J12Rik; 3110040D16Rik; Larp;
                     mKIAA0731"
                     /inference="alignment:Splign:2.1.0"
     exon            1607..1776
                     /gene="Larp1"
                     /gene_synonym="1810024J12Rik; 3110040D16Rik; Larp;
                     mKIAA0731"
                     /inference="alignment:Splign:2.1.0"
     exon            1777..2169
                     /gene="Larp1"
                     /gene_synonym="1810024J12Rik; 3110040D16Rik; Larp;
                     mKIAA0731"
                     /inference="alignment:Splign:2.1.0"
     exon            2170..2293
                     /gene="Larp1"
                     /gene_synonym="1810024J12Rik; 3110040D16Rik; Larp;
                     mKIAA0731"
                     /inference="alignment:Splign:2.1.0"
     exon            2294..2499
                     /gene="Larp1"
                     /gene_synonym="1810024J12Rik; 3110040D16Rik; Larp;
                     mKIAA0731"
                     /inference="alignment:Splign:2.1.0"
     exon            2500..2606
                     /gene="Larp1"
                     /gene_synonym="1810024J12Rik; 3110040D16Rik; Larp;
                     mKIAA0731"
                     /inference="alignment:Splign:2.1.0"
     exon            2607..2758
                     /gene="Larp1"
                     /gene_synonym="1810024J12Rik; 3110040D16Rik; Larp;
                     mKIAA0731"
                     /inference="alignment:Splign:2.1.0"
     exon            2759..2903
                     /gene="Larp1"
                     /gene_synonym="1810024J12Rik; 3110040D16Rik; Larp;
                     mKIAA0731"
                     /inference="alignment:Splign:2.1.0"
     exon            2904..3013
                     /gene="Larp1"
                     /gene_synonym="1810024J12Rik; 3110040D16Rik; Larp;
                     mKIAA0731"
                     /inference="alignment:Splign:2.1.0"
     exon            3014..3141
                     /gene="Larp1"
                     /gene_synonym="1810024J12Rik; 3110040D16Rik; Larp;
                     mKIAA0731"
                     /inference="alignment:Splign:2.1.0"
     exon            3142..6617
                     /gene="Larp1"
                     /gene_synonym="1810024J12Rik; 3110040D16Rik; Larp;
                     mKIAA0731"
                     /inference="alignment:Splign:2.1.0"
     regulatory      6595..6600
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Larp1"
                     /gene_synonym="1810024J12Rik; 3110040D16Rik; Larp;
                     mKIAA0731"
                     /note="hexamer: AATAAA"
     polyA_site      6617
                     /gene="Larp1"
                     /gene_synonym="1810024J12Rik; 3110040D16Rik; Larp;
                     mKIAA0731"
                     /note="major polyA site"
ORIGIN      
        1 gagccttctg cccggcgcgc cactcagcgt cagcccgtcc gcgccgctcc gcgtccgcgc
       61 ggcccgggct ccggcgcccc gccagcggcc tcgagcgggg cccgcggcgc gcccggcccc
      121 tccgcgcaga tggccactca agtggagccg ctgctgccgg cgggcgcccc gctgctgcag
      181 gccgaggagc acggcctggc gaggaagaag ccggcgcccg acgcccaggc cgagtcgggc
      241 ccgggtgacg gcggcggaga gcccgacggc ggcgtccgca ggccgcggcc cgcctgcgcc
      301 aggcctggcc gcgacggcgc ggagcgcgag agcccgcggc cacccgcagc tgcggaagcc
      361 ccagcgggga gcgacggcga ggacggcggc cggcgtgact tcgtggaggc accgccgccc
      421 aaggtgaacc cgtggacgaa gcacgcgccg ccgccggccg cggtgaacgg acagccgcct
      481 ccagaacctt ctgctccagc caaggtggtg agggcagctg ctcctaaacc gcgtaagggc
      541 agcaaggttg gtgattttgg agatgcagtc aactggccta cacctggaga gatagcccac
      601 aaaagtgtgc agccacagtc ccacaagcct cagcctgctc gtaagttgcc acctaagaag
      661 gacatgaagg agcaagagaa aggagatgga agtgatagta aggagagccc aaaaacaaag
      721 tcggatgaat cgggggagga aaagaatggg gatgaggact gccagcgagg cgggcagaag
      781 aagaaaggga gcaaacacaa gtgggttcca ttgcaaatag acatgaagcc cgaagtaccc
      841 agagagaaat tggcctcccg tcccactcgc ccacaggaac caagacatac acccgctgtc
      901 cgtggggaga tgaaaggatc tgaacctgcc acctacatgc ctgtatctgt ggccccaccc
      961 accccagcct ggcaaccaga gaccaaagtg gagcctgcct ggcacgacca ggatgagaca
     1021 tcgagtgtga agagtgatgg ggctggtggg gctcgggctt ccttccgtgg ccgtggacgg
     1081 gggcgtggtc gtggacgggg ccgtggacgg ggtggcactc gaacccactt tgactaccag
     1141 tttggctacc gaaagtttga tggtacagag gggccccgca cccacaagta tatgaacaac
     1201 atcacttact actttgacaa tgtcagcagc aatgagattt acagtatgga ccaggagctg
     1261 ctcaaggatt atatcaaacg ccagattgaa tattacttca gcgtggacaa tttagagcga
     1321 gacttcttcc tgagacggaa aatggatgct gatggcttcc ttcccatcac ccttattgct
     1381 tcctttcacc gtgtacaggc cctaaccact gacatttcac tcatctttgc ggctctaaag
     1441 gacagcaagg tggtagagat ggttgaggag aaagtccgca ggagggaaga acctgaaaag
     1501 tggccactgc ctggaccccc aatagtggat tattcacaaa ctgatttttc tcagcttctc
     1561 aactgcccag agtttgttcc ccgccagcac taccagaaag agacagagtc ggcacctggc
     1621 tctccccgtg cagtcacccc agtgccaaca aaaacagagg aggtcagcaa cctgaagacc
     1681 cttcccaagg gcctgtctgc cagcctccca gatctggatt ctgagagctg gattgaagtg
     1741 aagaaaaggc ctcgaccctc accagcacgc cccaagaagc cagaggagcc caggttctcc
     1801 cacccaactg ctctgcctca gcagcttccc tcccagcagc tgatgtctaa ggatcaggat
     1861 gagcaagaag aactagactt tctgtttgac gaggagatgg agcagatgga tgggcggaag
     1921 aataccttca ctgcctggtc tgaagaggac tctgactatg aaattgatga ccgggatgtc
     1981 aataagatcc tcatcgtcac tcaaacacca ccttacatgc gtcgccaccc tggaggagac
     2041 cgtacaggca accacacttc gcgtgccaag atgagtgctg aactggccaa ggtcattaat
     2101 gatggactct tctactatga acaagacctg tggactgaga agtttgagcc tgagtattca
     2161 cagatcaagc aagaagtgga aaacttcaag aaagtgaata tgattagtcg ggaacagttt
     2221 gacactctga cccctgagcc ccctgtggat cctaaccagg aggttcctcc tgggccacct
     2281 cggttccaac aagttcctac tgatgccctg gccaacaagc tgtttggtgc tcccgagcca
     2341 tctaccattg cccgttctct accaaccact gtcccagagt ctccaaacta ccgaaatgcc
     2401 aggactcccc gcacaccccg gaccccccag ctcaaagact ctagtcagac accacggttt
     2461 taccctgtgg tgaaagaagg acggacccta gatgccaaga tgcctcgaaa aagaaagaca
     2521 aggcacagct cgaacccccc cttggaaagt catgtgggct gggtgatgga ttctcgggag
     2581 cacaggccca ggactgcttc tattagctcc agtccttcag agggaacacc tgcagtcggc
     2641 agctatggct gtacccctca gtcactgccc aagttccagc atccttccca tgagctgctc
     2701 aaggaaaatg gcttcacaca acacgtctac cacaagtatc ggaggcgctg ccttaatgag
     2761 cggaagcgct tgggcattgg ccagtctcag gagatgaaca ccctcttccg cttttggtcc
     2821 ttcttcctcc gagatcactt caataaaaag atgtatgaag agttcaagca gctcgcactg
     2881 gaggatgcca aagaaggcta caggtacggt ttggagtgcc tttttcgata ctacagttat
     2941 ggtctagaga aaaagttccg gctggacata ttcaaggatt tccaggagga gacagtgaag
     3001 gactatgagg ctggccagct ctatggattg gagaagttct gggccttctt gaaatactcc
     3061 aaagccaaaa atttggacat tgaccccaaa ctgcaagaat acctcggcaa attccgccgc
     3121 ttagaagact tccgagtgga cccccccatg ggcgaggaag gcaaccacaa gcgacaccca
     3181 gtggtagcag gaggcagcgg agagggcagg aagcggtgcc cttcccagtc ttccagcagg
     3241 cctgccactg ggatcagcca accccctacg acacctactg gccaggccac tcgagaagat
     3301 gccaaatgga caagccagca ctcggacaca ctgactttgc gaaagtgaat ggcctgaagc
     3361 cccctggggt ttgtgataga ggggtggggt ggttgaggat ctgtggggtg cccagaagag
     3421 cgaacaagag aagggacaga cctagagtac taagaatggg cctttgcgct aagtagcagt
     3481 gtataccatt tgggctatta gcggtgctcc tgggcaggag cctccaagta ccccatccct
     3541 cctgtcacca tgacttccat cataacttct aaggggggag gggaaggggg gagattttat
     3601 atatatatat atatatatat acatatatat atatcaagtt ttaaattatt gatagtttgt
     3661 ctggattacc aaaatcactc tttagccctt cctgcggcta ttatgccgac ctgtctcccc
     3721 tgcctcttcc cgcttccctc aagccaacta tgcagcccac cagaaggctc tggcggtgcc
     3781 catgggcccc agaagcacca gccccttgat cacctggggt ttgccatcac cgtgtccctg
     3841 ctgttccaca tgcccttctg ccacctctgg gggaaggaaa ccaaaggatc tcagtggggg
     3901 tgggagcttc agcctctccc ctcgccccct cgccccaccc cagagacgct gctcacacca
     3961 gaagagacta ttgaaagatg attcatttta ttttttctct gacctttcca tccttgggaa
     4021 aacagaaaaa caaaacaaaa aaacaaaaaa aaaacaaaaa cgaaaataaa aaagaaagaa
     4081 agaagaaaga aaaaaaaaag acaaaatcga ccactttaaa aaaaaaaaaa agacaaaaaa
     4141 ccagagccca cctactccat agaaagtgat gtctttcccc ctccttggaa tttttcttct
     4201 gttctgtttt tggaaataat atttttttaa aagttgcctt attgtggagc gggaacctga
     4261 actaatgccc aaatgcctgt tttccttgag cctccggaag agctccacct gcccgggatg
     4321 tccctggact tggactgact agaactttcc tcgagactga gttgcatgta cggggcctcc
     4381 tacctggagg caagagttgg ggcagttcta tcagagctgt gcccaggaca cccctgctgt
     4441 tgcattgtct gaagccaatg tcctgtgtct gcacactgtt gccactgtcc ttgttgtgct
     4501 tgctgtcgcc tctccaggcc cactcagctc tgctccgccc cgccccgccc agccaagccc
     4561 tgggaaaccc caaggccaag tttgcttcag actgttgtaa acataattgg tcttgcctgg
     4621 tacacacttg tcctcagtgt gcacatctcc ccaactccag aacaaggggt tgaacaccca
     4681 ctgatgtcca cagcttaggt ctgtgtctaa ccttaacgac ctttgacctc aaggaggtgg
     4741 agaaaaggta ccattctcta agggtctggt gttgtctttc catcttatta ccaccacccc
     4801 ctgcaagcca tctctgccca ccctctcatt ggccctgcct gggatcaagg gggtgagagg
     4861 aaccaagggc tggggaatcc taccgtttgg tgaagcccca tggcaggaag gtatatgtgg
     4921 acatagagta tacctgactt ctcttcaaaa gccagactgc ctgagctgca cttgagatgc
     4981 cagaggagtg gctggaggct gctgtcacca ggagctgagg agggtaatga aggactgagc
     5041 acacaggctg ggagacttca tgctaaccct acacttggac ctaggtggca caagggggtg
     5101 tggtcttttt gctagcttaa ctgaaatttg tgtgaccctc ctcatcgccc agttcctcta
     5161 ttgtcccaaa agttgggact gggacacagc atcccaggct gacaagagct tgccttctgt
     5221 ctttgggcac cttgttactt tgagctcatg ccttgcccca ctctgtcctc ccggtgctta
     5281 ggatgtggga atcccttgtc agctcctgtg actcacttgt cgcaaacaaa taagggaaca
     5341 ggatcatctg ctgctgggat ctgaggcctt ctcctaagtc tggtacctgc cctatggtgc
     5401 accttcacca aacagtgggc tccctgcttc cctttctcct ctcctctcct cactcagccc
     5461 tctactgtat atccagcacc acagaacctc agggcttgag gcccagcatc agggaaggtg
     5521 gtttccatct aggctatcca gactagggtt gccattctct cccagatcct cccagaccct
     5581 ctgagggaag aagcccctct ggggtgggaa ggcaaggcta tcatctcaac acaggctgag
     5641 gaggggtggg agtgtgtgtg tgtgtgtgtg tgtgtgtgtg tgtgtgtgta ttttttgtga
     5701 catgttaaga gttgatgttg cggagtagtt tacatcttca ccttctgaag acacttgaat
     5761 ttaggaccga tgtatctgtg acaagtatgc caggagtggg ggtggggcac cagagcaagc
     5821 cacttcccca tcaccatctt cccatggaat ccaagaccta agacagacag cctgccaaat
     5881 ggaaccgcct tcatcctctg cctgtgcagg gttagacatc cacctggccc cagcaagggg
     5941 cagatggtgg tttgcaaacc tgtgagcctc agagcagatt tgctactcgg agggaaggct
     6001 gcctggccct gctccagcct ggaccgcagg ttcagacagg tgctgagccc cgggtcaagt
     6061 tgttcaatgt ttttgttctg tagctccttc ccactccttt ttgatgacat ttacaaaaga
     6121 aggcaagctg cttggaaggt ctggacatga gggaaagggc attgaggaca aggctaatgg
     6181 tggggagtgc tagaggcttg ggttcccctg tcccctggat gggaccccag agtctcttgt
     6241 cacagggccc ctaggttttc cccagctccc accctctcct ccagccatgg ttacggcaga
     6301 ggcagaagaa aactttgagc ccagttctca caggaaagga aaactctcat gggctttgca
     6361 gagaaggttc cacctacgct catatattgt ctttaccatg tgctaggata tcacatcaac
     6421 aggacaagaa aaatgtaaaa tacttgaatg agcttgtatt ataacattaa tattattgag
     6481 agtgtctgct tcccaggctg aagtgattca ttcattattc tggtcctgct ctagtccttt
     6541 gtaattggtg gtaattatta tgcttttctt tttaatacaa aaaaaatgta taaaaataaa
     6601 aacttgaaaa ggcaaaa
//
