LOCUS       NM_133664               2992 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus ladinin (Lad1), mRNA.
ACCESSION   NM_133664
VERSION     NM_133664.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2992)
  AUTHORS   Walentin,K., Hinze,C., Werth,M., Haase,N., Varma,S., Morell,R.,
            Aue,A., Potschke,E., Warburton,D., Qiu,A., Barasch,J., Purfurst,B.,
            Dieterich,C., Popova,E., Bader,M., Dechend,R., Staff,A.C.,
            Yurtdas,Z.Y., Kilic,E. and Schmidt-Ott,K.M.
  TITLE     A Grhl2-dependent gene network controls trophoblast branching
            morphogenesis
  JOURNAL   Development 142 (6), 1125-1136 (2015)
   PUBMED   25758223
REFERENCE   2  (bases 1 to 2992)
  AUTHORS   Neidhardt,L., Gasca,S., Wertz,K., Obermayr,F., Worpenberg,S.,
            Lehrach,H. and Herrmann,B.G.
  TITLE     Large-scale screen for genes controlling mammalian embryogenesis,
            using high-throughput gene expression analysis in mouse embryos
  JOURNAL   Mech Dev 98 (1-2), 77-94 (2000)
   PUBMED   11044609
REFERENCE   3  (bases 1 to 2992)
  AUTHORS   Motoki,K., Megahed,M., LaForgia,S. and Uitto,J.
  TITLE     Cloning and chromosomal mapping of mouse ladinin, a novel basement
            membrane zone component
  JOURNAL   Genomics 39 (3), 323-330 (1997)
   PUBMED   9119369
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK083526.1.
            
            On Apr 5, 2007 this sequence version replaced NM_133664.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK083526.1, BC031131.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2992              AK083526.1         2-2993
FEATURES             Location/Qualifiers
     source          1..2992
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 59.3 cM"
     gene            1..2992
                     /gene="Lad1"
                     /gene_synonym="lad-1; LADA"
                     /note="ladinin"
                     /db_xref="GeneID:16763"
                     /db_xref="MGI:MGI:109343"
     exon            1..419
                     /gene="Lad1"
                     /gene_synonym="lad-1; LADA"
                     /inference="alignment:Splign:2.1.0"
     CDS             382..1968
                     /gene="Lad1"
                     /gene_synonym="lad-1; LADA"
                     /note="linear IgA disease antigen homolog"
                     /codon_start=1
                     /product="ladinin-1"
                     /protein_id="NP_598425.2"
                     /db_xref="CCDS:CCDS35723.1"
                     /db_xref="GeneID:16763"
                     /db_xref="MGI:MGI:109343"
                     /translation="MSVSRKDWSALSSLARQRTLEDEEEQERERRRRHRNLSSTTDDE
                     SPKLTQNGAQRSVERLPSVEEAEVSKPSPPASKDEDEDFQAILRTRKERRQRRQVVEA
                     VQAPVQERPEAEEERDSLGPEQTSSQPLVPKKKVEALPRRRLSREQRGPWAQDEERLK
                     NRELAEGEKRLPEETVAQQKTLVSEKTPVSEKTPVPAKRLVSEKACPSEKGTATEKAS
                     LTEKRHSPEKLVPEKTSVTEKSPVPEKTLVSLKTAAPERRSPPVLEKAIVSEKMQERK
                     LVSEKASIFEKSLVSEAKLTPKKAAVSEQPQTTGGSQATTREPRGRALPDKSPPSSAE
                     QSTPAPPTKASRFPPITLQVKIPSKDEDADTPSPTLLTYSSSLKRSSPRTISFRMSPR
                     KDNSETPLTRSASVRLPASTVKLGEKLERYHTAIQRSESVRSPGSSRTEVLVTPAGVA
                     SKRHLFEKELSGQNRTEPTSIRKENLRLSGVVTSRLNLWISKTQDSGDHGSQEVRKEA
                     SVTKRAQWGSKPSTSLDAEV"
     exon            420..557
                     /gene="Lad1"
                     /gene_synonym="lad-1; LADA"
                     /inference="alignment:Splign:2.1.0"
     exon            558..1440
                     /gene="Lad1"
                     /gene_synonym="lad-1; LADA"
                     /inference="alignment:Splign:2.1.0"
     exon            1441..1545
                     /gene="Lad1"
                     /gene_synonym="lad-1; LADA"
                     /inference="alignment:Splign:2.1.0"
     exon            1546..1589
                     /gene="Lad1"
                     /gene_synonym="lad-1; LADA"
                     /inference="alignment:Splign:2.1.0"
     exon            1590..1662
                     /gene="Lad1"
                     /gene_synonym="lad-1; LADA"
                     /inference="alignment:Splign:2.1.0"
     exon            1663..1800
                     /gene="Lad1"
                     /gene_synonym="lad-1; LADA"
                     /inference="alignment:Splign:2.1.0"
     exon            1801..1887
                     /gene="Lad1"
                     /gene_synonym="lad-1; LADA"
                     /inference="alignment:Splign:2.1.0"
     exon            1888..1962
                     /gene="Lad1"
                     /gene_synonym="lad-1; LADA"
                     /inference="alignment:Splign:2.1.0"
     exon            1963..2992
                     /gene="Lad1"
                     /gene_synonym="lad-1; LADA"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2593..2598
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Lad1"
                     /gene_synonym="lad-1; LADA"
                     /note="hexamer: GATAAA"
     polyA_site      2619
                     /gene="Lad1"
                     /gene_synonym="lad-1; LADA"
                     /note="major polyA site"
ORIGIN      
        1 actctggacc gcgactccca gggaagacgc gggccggcgc cgagctggtc caactggttc
       61 tgagcaggaa gtctcccgcc ctcgcccggg gcagcagagc agccccgcgc tagccccggc
      121 gtgggtgcag cccgcagctc ggtgcgaccg tcccgcagag cggccgcgcg ggagacccgc
      181 cccagcggtg atcagcgcgg ctttgtctgg gacgcccaca cctcagaggc cgctcctccg
      241 gccggcgaat gggagcgcgg cggcgcgggg ccgagccggg ctgagataag cggccatgtg
      301 accctacctg gcgcggggag gggccgcagg tgagcggcgg agcagggagc tcggcacgcg
      361 gcggccgtgg ggctcggcag catgtcggtc agcagaaagg actggtccgc gctgtccagc
      421 cttgcccgac agcggacttt ggaggacgaa gaggagcagg agcgggaacg caggcggagg
      481 caccgcaacc tgagttcaac cacagatgat gaatctccaa aactcaccca gaatggagct
      541 cagagatctg tggagaggct gcccagtgtg gaggaagcag aggtctctaa gccatcgccc
      601 ccagcctcca aagatgaaga tgaagacttc caggccatcc ttaggaccag aaaggagcgg
      661 agacagaggc ggcaggtggt agaggctgtc caggctccag tacaggagag gccagaggca
      721 gaggaggaaa gagacagcct gggccctgag cagacctcgt cacagcccct tgtgcctaag
      781 aagaaagtgg aggccctgcc tcgccggaga ctgagtcggg agcagagagg cccttgggcc
      841 caggacgaag aacgcctaaa gaacagagag cttgcggaag gagaaaagag gcttccagaa
      901 gagacggtgg ctcagcagaa gaccttggtc tctgagaaaa cgcctgtctc agagaagacc
      961 ccagtgcctg ccaaaagact ggtttctgag aaagcctgcc cctcagagaa ggggacagcc
     1021 acagagaaag cgtctctgac tgagaaaaga catagcccag agaagttggt tccagaaaaa
     1081 acaagtgtga cagagaagtc accggtccct gagaagacgc ttgtgtctct gaagacggca
     1141 gcaccagaga gaaggtcccc tccagttcta gaaaaagcca tcgtctcaga gaagatgcag
     1201 gagaggaagc tggtgtcgga gaaagcatcc atctttgaga agtcactagt ctcagaggca
     1261 aagctgacgc caaagaaggc agcagtgtca gagcagcccc agaccactgg gggaagccag
     1321 gccaccacga gggagcccag aggaagggcc ctccctgaca agagcccacc ttcttctgca
     1381 gagcagagca caccagcccc gccgaccaaa gcctctcgtt tcccacccat cacactccag
     1441 gtgaaaattc ccagcaagga tgaagatgca gacacacctt cacccaccct gctcacctac
     1501 agcagttccc tcaaacgctc cagccccagg accatctcct tccggatgag ccccaggaaa
     1561 gacaactcag aaacaccctt aacccgcagt gccagcgtga ggctgccggc tagcaccgtc
     1621 aagctagggg agaaactgga gagataccac acagccatcc agaggtcaga atccgtcagg
     1681 tctccaggct cctcccgtac tgaagtcctt gtcacacctg ccggtgtagc cagcaagcga
     1741 cacctctttg agaaggagct gtcaggccag aaccgcacag aaccaacctc catccgaaag
     1801 gagaatctgc gtctgtcagg ggtcgtgaca tcaagactta acctgtggat cagcaagacc
     1861 caggattcgg gagaccacgg ttctcaggag gtacggaaag aggcatcagt caccaagagg
     1921 gctcaatggg gaagcaagcc gtccacatcc ctggatgcag aggtgtgaca agtcctgtca
     1981 ggacggacct gaaaacctgc atcccaaggg cccttcatca tgccggcccc tctcctgcag
     2041 aacccttgac tcttgcagac cccactccct tcccgcctct ggatcagtct ggtcagggtc
     2101 ctcaggggcc aggaacatga ctgccacgcc ttcagcccgt ctccagccca gactgtgggc
     2161 aggtgttctc tggaactttc ttgtcccgct gaaggtacaa tgtatcctga acccggaaag
     2221 tgccagagca cagccctggc ccgtcagcca tggagtgtcc atgtcctctc tagggactgc
     2281 ctccctttct cctactcacc tccaccatca agctgggtta ttttgccaac tgcagagtta
     2341 catgtctagc ctgctcccag caggcactcg gtgtgcctgt gatatctcca cactgagtgc
     2401 tagacctatt taccgctccc tgaggcttgt tcaagccaga ctggaaagga gtcgccaggc
     2461 tgcctatgtg ctacacccca ctgcttgcac tgtgttcccc accctcctgc tgccctgatc
     2521 gggaactcgg tgccttttcg tcttaccaca tgccttactc tcagccagaa aaacctttcc
     2581 caggaaggat ctgataaact cattcagtct caggtgtaag tgtctggtaa tgtcgatggc
     2641 tttgttctca caggttttgc gttccttccg aatcagctgc agggagtgag gcagcgttgg
     2701 cttcgctgga agaagaaacc cttccctcat tcccatctcc tctcatttta aggtcctagt
     2761 tttgtgatct aaggtcttaa ttgtgcatac ctggtgtcgg gagagatggc tcagcagtta
     2821 agaactctgg ctgctcttca ggggacgtag gctcaattcc cagcacctat acattggctt
     2881 ataaatgtct gaaaccccac ttttagggaa tttgtaggca ctgcatatac acatggtgtg
     2941 cagttataca tgcaagcaag gcacacataa aataaaaatc atttaagagc gc
//
