LOCUS       NM_028184               2005 bp    mRNA    linear   ROD 07-AUG-2024
DEFINITION  Mus musculus ABCE maturation factor (LTO1), transcript variant 2,
            mRNA.
ACCESSION   NM_028184 XR_105180 XR_107965 XR_107966
VERSION     NM_028184.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2005)
  AUTHORS   DeChiara,T.M. and Brosius,J.
  TITLE     Neural BC1 RNA: cDNA clones reveal nonrepetitive sequence content
  JOURNAL   Proc Natl Acad Sci U S A 84 (9), 2624-2628 (1987)
   PUBMED   2437583
  REMARK    Erratum:[Proc Natl Acad Sci U S A 1987 Jul;84(14):4895]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC161763.3.
            
            On May 4, 2022 this sequence version replaced NM_028184.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC013564.1, AK169310.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            RefSeq Select criteria           :: based on conservation,
                                                expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-185               AC161763.3         98781-98965         c
            186-291             AC161763.3         97577-97682         c
            292-362             AC161763.3         96430-96500         c
            363-480             AC161763.3         94769-94886         c
            481-2005            AC161763.3         92976-94500         c
FEATURES             Location/Qualifiers
     source          1..2005
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 88.92 cM"
     gene            1..2005
                     /gene="LTO1"
                     /gene_synonym="2210010N10Rik; Oraov1; TAOS1"
                     /note="ABCE maturation factor"
                     /db_xref="GeneID:72284"
                     /db_xref="MGI:MGI:1919534"
     exon            1..185
                     /gene="LTO1"
                     /gene_synonym="2210010N10Rik; Oraov1; TAOS1"
                     /inference="alignment:Splign:2.1.0"
     CDS             136..549
                     /gene="LTO1"
                     /gene_synonym="2210010N10Rik; Oraov1; TAOS1"
                     /note="isoform 2 is encoded by transcript variant 2; oral
                     cancer-overexpressed protein 1 homolog; oral cancer
                     overexpressed 1; protein LTO1 homolog"
                     /codon_start=1
                     /product="protein LTO1 homolog isoform 2"
                     /protein_id="NP_082460.3"
                     /db_xref="CCDS:CCDS22054.1"
                     /db_xref="GeneID:72284"
                     /db_xref="MGI:MGI:1919534"
                     /translation="MAVEQDIFDAVVMADERFHGEGYQEGYEEGSSLGIVEGKRYGMV
                     HGAKIGSEIGCYRGFALAWKCLLHSGAGEKDSRKMKVVEALIALLQDFPYDDPTYEKL
                     HEDLDRIRGKFRQLCSLLNVQPDFKVTPGGSGLAF"
     exon            186..291
                     /gene="LTO1"
                     /gene_synonym="2210010N10Rik; Oraov1; TAOS1"
                     /inference="alignment:Splign:2.1.0"
     exon            292..362
                     /gene="LTO1"
                     /gene_synonym="2210010N10Rik; Oraov1; TAOS1"
                     /inference="alignment:Splign:2.1.0"
     exon            363..480
                     /gene="LTO1"
                     /gene_synonym="2210010N10Rik; Oraov1; TAOS1"
                     /inference="alignment:Splign:2.1.0"
     exon            481..2005
                     /gene="LTO1"
                     /gene_synonym="2210010N10Rik; Oraov1; TAOS1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      594..599
                     /regulatory_class="polyA_signal_sequence"
                     /gene="LTO1"
                     /gene_synonym="2210010N10Rik; Oraov1; TAOS1"
                     /note="hexamer: ATTAAA"
     polyA_site      616
                     /gene="LTO1"
                     /gene_synonym="2210010N10Rik; Oraov1; TAOS1"
                     /note="major polyA site"
     regulatory      1983..1988
                     /regulatory_class="polyA_signal_sequence"
                     /gene="LTO1"
                     /gene_synonym="2210010N10Rik; Oraov1; TAOS1"
                     /note="hexamer: AATAAA"
     polyA_site      2005
                     /gene="LTO1"
                     /gene_synonym="2210010N10Rik; Oraov1; TAOS1"
                     /note="major polyA site"
ORIGIN      
        1 ctgctccgcg cggcatacac ggaagtgtct tcttcattct gacaatccgg gcgtttgtga
       61 tcgcgtctcg ccagttggcg attactacac agaatgaaag gaatgcgagg gccgggggag
      121 agccgagaca ccgccatggc cgtggagcag gacatatttg acgccgtcgt gatggcggat
      181 gagagattcc atggggaggg atatcaggaa ggctatgaag aaggcagtag cttggggatc
      241 gttgaaggaa agcggtatgg catggtacat ggagccaaga ttgggtctga gattggatgc
      301 taccggggtt ttgctcttgc atggaagtgt ctcctacaca gtggcgctgg tgaaaaagac
      361 agcaggaaga tgaaggtggt ggaggctctg attgcgctgc tgcaggactt tccttacgat
      421 gatcccactt atgagaagct ccatgaagac ctggacagaa tcagagggaa gttcaggcag
      481 ctgtgctcac tgctcaacgt gcagccagac ttcaaggtga ctccaggagg ctctggactt
      541 gcgttttgag gacccacaga agagcagatg tctgcacatt aagtgtcaca gtgattaaag
      601 gcaagcctga gaggaatcca ttgttctgtg ggaggaccag cttggcctct tccctgagtc
      661 tctgcctagg tggcttacct gaccaccctg ccttctgcac aggggcaaca cactcaaaag
      721 accgcttgtc actggccaga gtgagtggcc ctgggtaggg ttaccctgag ggtgggactc
      781 acagaggcag gccgatgtga aatgggtcat gggaagccgt gataagatct ttgctgcctg
      841 ctgagcctct gctggccatg cttgggcctc cttgtttcac tccatccctc tggcagcccc
      901 agaggtggag gataccttat ggcttagaag tgataaaata gacccatcta gtctaagggc
      961 ctggtggcag agctggcccc caccccaggt ccatgccctg aagtaccaca tagtgcctct
     1021 gcctccaaca tgcgctgtca ttgccaacac cactggagga cctgattcct gctatctgca
     1081 caggactcag gctccactgg acttggtttg cctctggatg cccagctgag aaaacaaggg
     1141 tgacgagaca agggaggaag ctgaagcagg gccttcatgc tgctcctaac aggtgtgggg
     1201 tgagctctat acattaagga gtggcaatgg agctgggtgc tggtggtgca cgcctttaat
     1261 cccagtgctc aagagatagt aggcagatct ctcagtttga ggtcagccta gtctacaaag
     1321 tgaattcaaa accaaacaaa caaaaagtgg cattagggga actattggaa accaaagcag
     1381 gactaattgg tggccgccac tgtgaatgtg tagggcttgc ctggtgacac tgtacttcct
     1441 ttagcaacag cttgtgtgtc tggcatggta tttacaggca gatataagac gagctggcag
     1501 gagtggcaca gtgctctcag gcatttcata gagagaatat ctttgtgttg tatggatgcc
     1561 tcacctgtgg caaaaagcct atggcctatg gcttaggcag gaaataggcg gaacatctgg
     1621 gagagagaaa gcattctggg atagagccag gtgggagatc taccagggag gatgtgagga
     1681 gatggacaca tggtacctga gcacaggtaa ccagccagct ggcagaatgc aggttaaaat
     1741 aaatgggtta tcttcagtta taatctagtc agaatagagc ctagctgtat gtccgaagga
     1801 tttgtaaata tgttttgagt ctgaggcttg gggcaccatg cacctggcct cctgggcctg
     1861 gcggctacct ctcaggtatt cagcaccact ctctcaggtg cccaggatca gggactcttc
     1921 ggtgtgagaa ctgagctgct gttatcacca tattttactt tcctattata ttcagaaaaa
     1981 agaataaatg gtgtatttta aagca
//
