LOCUS       NM_177278               4570 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus L3MBTL4 histone methyl-lysine binding protein
            (L3mbtl4), mRNA.
ACCESSION   NM_177278
VERSION     NM_177278.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4570)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 4570)
  AUTHORS   Bailey,P.J., Klos,J.M., Andersson,E., Karlen,M., Kallstrom,M.,
            Ponjavic,J., Muhr,J., Lenhard,B., Sandelin,A. and Ericson,J.
  TITLE     A global genomic transcriptional code associated with CNS-expressed
            genes
  JOURNAL   Exp Cell Res 312 (16), 3108-3119 (2006)
   PUBMED   16919269
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK053068.1, AC117803.12, CT010483.12, AC154493.2, AC191933.3,
            AK139210.1 and BB548625.2.
            
            [WARNING] On Aug 15, 2024 this sequence was replaced by
            NM_177278.6.
            
            On Oct 12, 2007 this sequence version replaced NM_177278.4.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data because no single transcript was available
            for the full length of the gene. The extent of this transcript is
            supported by transcript alignments and orthologous data.
            
            ##Evidence-Data-START##
            RNAseq introns :: partial sample support SAMN01164138, SAMN01164139
                              [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            RefSeq Select criteria    :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1363              AK053068.1         2-1364
            1364-1449           AC117803.12        83055-83140         c
            1450-1675           AK053068.1         1365-1590
            1676-1778           CT010483.12        108900-109002
            1779-1952           CT010483.12        151988-152161
            1953-2023           CT010483.12        163302-163372
            2024-2036           AC154493.2         112463-112475
            2037-2050           AC154493.2         127228-127241
            2051-2192           AC191933.3         40664-40805         c
            2193-3430           AK139210.1         2-1239
            3431-4154           AC191933.3         25686-26409         c
            4155-4570           BB548625.2         239-654
FEATURES             Location/Qualifiers
     source          1..4570
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 39.3 cM"
     gene            1..4570
                     /gene="L3mbtl4"
                     /gene_synonym="A730037L19Rik; D930040M24Rik"
                     /note="L3MBTL4 histone methyl-lysine binding protein"
                     /db_xref="GeneID:320858"
                     /db_xref="MGI:MGI:2444889"
     exon            1..94
                     /gene="L3mbtl4"
                     /gene_synonym="A730037L19Rik; D930040M24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            95..549
                     /gene="L3mbtl4"
                     /gene_synonym="A730037L19Rik; D930040M24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            550..651
                     /gene="L3mbtl4"
                     /gene_synonym="A730037L19Rik; D930040M24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            652..706
                     /gene="L3mbtl4"
                     /gene_synonym="A730037L19Rik; D930040M24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            707..798
                     /gene="L3mbtl4"
                     /gene_synonym="A730037L19Rik; D930040M24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            799..903
                     /gene="L3mbtl4"
                     /gene_synonym="A730037L19Rik; D930040M24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            904..1039
                     /gene="L3mbtl4"
                     /gene_synonym="A730037L19Rik; D930040M24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1040..1131
                     /gene="L3mbtl4"
                     /gene_synonym="A730037L19Rik; D930040M24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1132..1286
                     /gene="L3mbtl4"
                     /gene_synonym="A730037L19Rik; D930040M24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1287..1363
                     /gene="L3mbtl4"
                     /gene_synonym="A730037L19Rik; D930040M24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1364..1449
                     /gene="L3mbtl4"
                     /gene_synonym="A730037L19Rik; D930040M24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1450..1560
                     /gene="L3mbtl4"
                     /gene_synonym="A730037L19Rik; D930040M24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1561..1675
                     /gene="L3mbtl4"
                     /gene_synonym="A730037L19Rik; D930040M24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1676..1778
                     /gene="L3mbtl4"
                     /gene_synonym="A730037L19Rik; D930040M24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1779..1952
                     /gene="L3mbtl4"
                     /gene_synonym="A730037L19Rik; D930040M24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1953..2023
                     /gene="L3mbtl4"
                     /gene_synonym="A730037L19Rik; D930040M24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2024..2036
                     /gene="L3mbtl4"
                     /gene_synonym="A730037L19Rik; D930040M24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2037..2050
                     /gene="L3mbtl4"
                     /gene_synonym="A730037L19Rik; D930040M24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2051..2220
                     /gene="L3mbtl4"
                     /gene_synonym="A730037L19Rik; D930040M24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2221..2283
                     /gene="L3mbtl4"
                     /gene_synonym="A730037L19Rik; D930040M24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2284..4570
                     /gene="L3mbtl4"
                     /gene_synonym="A730037L19Rik; D930040M24Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4241..4246
                     /regulatory_class="polyA_signal_sequence"
                     /gene="L3mbtl4"
                     /gene_synonym="A730037L19Rik; D930040M24Rik"
                     /note="hexamer: AATAAA"
     polyA_site      4269
                     /gene="L3mbtl4"
                     /gene_synonym="A730037L19Rik; D930040M24Rik"
                     /note="major polyA site"
     regulatory      4292..4297
                     /regulatory_class="polyA_signal_sequence"
                     /gene="L3mbtl4"
                     /gene_synonym="A730037L19Rik; D930040M24Rik"
                     /note="hexamer: AATAAA"
     polyA_site      4319
                     /gene="L3mbtl4"
                     /gene_synonym="A730037L19Rik; D930040M24Rik"
ORIGIN      
        1 aggtgcggca ggagcatgcg cgtgcgcggt gggggcgttt cccgcgcccg gggccggtgc
       61 acctcacccg cggcagctgc tgcgggacac tgggatatgg aggggatcta gaatctgaca
      121 gtggccttac ctcaaagtgc tttatctggg aacagtctgc ctttcgacaa gtcacttcca
      181 gaacattcta aggaactggc acatgccgtt gcacccaggc agagagtgag ataagaacgc
      241 gctggagact gtcttgtatt cagccttcaa gaaacttttg caagattgtc tcatttagta
      301 ggaaaagcca catgcacaaa ctagcagtct tccccgggac cagaggagag agcagaactg
      361 atgctgtgtg ctctcaccca ccagagtgcc gcaagccagt tcccagctcc agctaccagt
      421 ttccaggaag aacacgctgt ctgagcaggg aggacttggg gagagagttt cttcagaatc
      481 cacttaagtt taagatggtg tctggaggcc tgtgaacctc cacttggcct tcacagtgac
      541 tgcttctaga aaacgcagcc agggagctct gaagtggaga tgagacaacc taaccggaag
      601 aggaagctca gcctagagtc tacagagcgc atgaatcagg acagatgcac ggggcaaact
      661 gaggaagaaa agaagccggg agaggtgacc acaccttcaa agcgagaatc ttctgtgact
      721 acagcggaaa cctggtcctg ggagcagtac ctgagagaag ggaacgctgt agctgcacca
      781 gtagaactgt tttccaagga ccaatccttt ccggagcatg aaaatggctt tcaggttgga
      841 atgaggttgg aaggcattga tgcccgacgt ccatctgtgt tctgtgtgct ttctgtagca
      901 gaggtgtgtg gctaccggct gagactgcat tttgatggtt atttaagctg ctatgatttt
      961 tggaccaatg ctggttcccc ggacattcac ccagtgggat ggtgtcaaaa gaccaagcat
     1021 gaactgcata tccctcggga ttatagaaaa gataaatttg tttggatgga ttacttgaag
     1081 gcctgtagat tgcaaaatgc tcctaagaaa ttattcagaa acagaagttc taatggtcca
     1141 gtgccaaggg agtttcaagt tgggatgaag ctggaggctg tggacaggag gaacccttgc
     1201 ttgatgtgtg tggcaaccat tgcagacatt gtggaagacc gagtccgggt gcattttgac
     1261 agcttggatg acagctttga ttactggtgt gatgttaaca gcccttacat ccagccggtt
     1321 ggttggtgtc aggagaacgg aagaactctg gtcgctcccc aaggttatcc tcatccagat
     1381 aagttttcct ggacagacta cctgcgagct tctcaatcga aggcagtgcc cgccaaggcc
     1441 tttggcatga ggactccaca tggttttttg ccaaacatga agttggaagc tgtggacaaa
     1501 aggaaccccc agttgattcg tgttgctacc attgccgatg ttgatgacta cagagtaaag
     1561 attcatttcg atggctggga ccataagtac gactattggg tggatgccga cagccaggac
     1621 atccacccca tcgggtggtg cgatgtgaca gggcatccgc tggaagtgcc atatgggtca
     1681 aagcatgtga aaatccttcc aggtcaacct gcatgtccta ctcctgggtg ccgaggcata
     1741 ggtcatatcc gtggcccacg ttatgcagga caccacagtg cttttgggtg cccgtactca
     1801 gatgtgaact tgaaaagaga ggcagccctt caggatcgcc tgagagaaca aacacaggca
     1861 aatttggaac ttgatccttc acattccaaa tcagaaaacc cctgtaattt gaatgtcaac
     1921 ggaaaatgtg aaaatgcaaa cagtcagtgc agacttgtac agcaggcaaa gtgtttgaaa
     1981 atcaaaggaa aagaagatat tgacttggat aatctcttca gagtcctggt tttccatcct
     2041 cgaaggctag agtactcagc tgcacaggtg cagcagatgc ttcaccagcc gctctccatg
     2101 acatccacgt ctgcccaccc tttccgagac atccccctca gcagggagca gcactgcaag
     2161 ctgcttccag gtgtggctga catccaagcc agtcaagtgg ccagatggac agtggatgag
     2221 gtggctgagt ttgtgcagtc tcttctgggc tgtgaagaac acgccaagtg cttcaagaag
     2281 gagcagatag atggcaaagc cttcctgctt ctgacccagg cagatattgt caaagtgatg
     2341 agaatcaagc tgggcccagc actgaagatc tacaactcta tcctgatgtt caggaactcc
     2401 caggatgtca ctgaagatgc ctctagccaa gaagacaaga gataaatgtg tttttggtca
     2461 tccactgata ccaggacttg cacgtttgag gacatggttg gcagccatcc atttgaattt
     2521 aatgtcccca ttagtgtacc aatatttaat caggaccctt taaagagtct ggtttaggca
     2581 tatggtggac tttgataaat gaccaagtgc caatgactta gatgcttagt ttggtccagg
     2641 tgtgggttta ggtggcatcc ttacggcttg gtgtgcttca gtcaacagat ttacgaagcc
     2701 actgtacgca tctctacact cccctctaaa agaaaacact tcccattccg caagtgtgtc
     2761 tcaagtggta aaatgccaga aaatcaattc actagtgcat tgttaacacg ttcaccagaa
     2821 ctactgagca cagcttgcat ctgttgtctg ggtgccttga gtggaagagc tggggtgctg
     2881 gtgctcttga gaagactcat gagatttctg gacccttaac tcaggaaagt atgaatcttt
     2941 ttcaaatgct aacaagcaca ttgttttcat gctccacaaa tcctcatttt tattccttac
     3001 catgccttgg ttgcagttcc aaggtaccct ggagcctact gcaaggagtg tgcctagaag
     3061 taacagagga gtgagtgttt ggaggccatc ccaggaacct gctgggacac tcctgatgac
     3121 ccacagtcag ggcacttgtt ctaacagtgg cattggtcaa agacctacct gcctgaaatt
     3181 cctccagctc ccaccctgac gaaccttcaa atggactctc cccttatcta ttgatttttt
     3241 ttttttttaa gcaatcaggt ctggtttcac ctctacagag gcatggcagc aggacagaag
     3301 acctccagag agcagctcag gatctgttga gtgtgtctga cattcaagtt gtgggaaggc
     3361 cacttcagag ttgcaaatga ttagaactcc aagtctacaa ctctttatcc ttttatcttt
     3421 tttctttttt tctgatcttt tttggttttt tattggattt tttctttatt tatatttcac
     3481 atgttttccc ctttccaggt ctccccttca gaaaccccct atctaatccc tgcttcctct
     3541 gcctctgtga gggtgctcct ccatgcatcc actcccacct tcctgccctg gcactccttt
     3601 acactgaggc attgaaaact ctcaggacca agggcctctc ctcccactga tgtacaacaa
     3661 ggccatcctc tgccacatat gtggccagag cctccatgtg tattctttgg tgatccagtc
     3721 cctaggaact ccgacgggcg ggggagtctg tcctgttgac actgttgctc cctccatggg
     3781 gctgcaaacc ccctcaggtc cttcattccc ttctccaact ccttcatcgg ggacttgcac
     3841 acttagtcca atggttggct acaagtatct gccttggtat ttgtcaggct ctggcagagc
     3901 ctctcaggag acagccttat cgggcttatc agcaagcact tcccagcatc caaaatagca
     3961 tccaggttta gtggctgtaa atgggatgga tccccaggta tggtctcttt gtccttttcc
     4021 atgtagtagc aatgaaagct atcctcctga aaacaaagag tcatctgact catccatcgg
     4081 gtgtgggaac ccaaatggaa gccacaagaa agaagcagac gtgacagtat ctccctgcta
     4141 cattaagaat gttcttaact taacaaagga tcatagtttc tactgtctgt gatgttttgt
     4201 ttattggagg tttttttttt tcttgtagag ttctatatgg aataaagaat tgctgcttct
     4261 accgttaaag tgagaacata ttttaaatgt taataaaatg tgaaagtaga ctcaccctgg
     4321 atgtgtggtc atagcctgtg ccttcctaca gtctagggtc agctatggaa gaacaaaggc
     4381 aactgcatgc attatccagc agagaaattt gctgtttctg actgctgtgt tccttagtgc
     4441 aggttctctt atggaaacag ttaagatggt aatagtgtga gagactgaat tgtaaagttt
     4501 ttaactaata caagctttag aattgctcat tttatatatt aaaaaaaaaa aaaaacctta
     4561 aggaagacct
//
