LOCUS       NM_029366               1236 bp    mRNA    linear   ROD 03-JUN-2024
DEFINITION  Mus musculus KxDL motif containing 1 (Kxd1), mRNA.
ACCESSION   NM_029366
VERSION     NM_029366.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1236)
  AUTHORS   Zhang,C., Hao,C., Shui,G. and Li,W.
  TITLE     BLOS1 mediates kinesin switch during endosomal recycling of LDL
            receptor
  JOURNAL   Elife 9, e58069 (2020)
   PUBMED   33179593
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1236)
  AUTHORS   Yordanov,T.E., Hipolito,V.E.B., Liebscher,G., Vogel,G.F.,
            Stasyk,T., Herrmann,C., Geley,S., Teis,D., Botelho,R.J., Hess,M.W.
            and Huber,L.A.
  TITLE     Biogenesis of lysosome-related organelles complex-1 (BORC)
            regulates late endosomal/lysosomal size through PIKfyve-dependent
            phosphatidylinositol-3,5-bisphosphate
  JOURNAL   Traffic 20 (9), 674-696 (2019)
   PUBMED   31314175
REFERENCE   3  (bases 1 to 1236)
  AUTHORS   Zhou,W., He,Q., Zhang,C., He,X., Cui,Z., Liu,F. and Li,W.
  TITLE     BLOS2 negatively regulates Notch signaling during neural and
            hematopoietic stem and progenitor cell development
  JOURNAL   Elife 5, e18108 (2016)
   PUBMED   27719760
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1236)
  AUTHORS   Pu,J., Schindler,C., Jia,R., Jarnik,M., Backlund,P. and
            Bonifacino,J.S.
  TITLE     BORC, a multisubunit complex that regulates lysosome positioning
  JOURNAL   Dev Cell 33 (2), 176-188 (2015)
   PUBMED   25898167
REFERENCE   5  (bases 1 to 1236)
  AUTHORS   Yang,Q., He,X., Yang,L., Zhou,Z., Cullinane,A.R., Wei,A., Zhang,Z.,
            Hao,Z., Zhang,A., He,M., Feng,Y., Gao,X., Gahl,W.A., Huizing,M. and
            Li,W.
  TITLE     The BLOS1-interacting protein KXD1 is involved in the biogenesis of
            lysosome-related organelles
  JOURNAL   Traffic 13 (8), 1160-1169 (2012)
   PUBMED   22554196
REFERENCE   6  (bases 1 to 1236)
  AUTHORS   Cho,A., Ko,H.W. and Eggenschwiler,J.T.
  TITLE     FKBP8 cell-autonomously controls neural tube patterning through a
            Gli2- and Kif3a-dependent mechanism
  JOURNAL   Dev Biol 321 (1), 27-39 (2008)
   PUBMED   18590716
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC157774.5 and BC038552.1.
            
            On Jul 31, 2009 this sequence version replaced NM_029366.1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC053944.1, BQ961051.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-107               AC157774.5         124720-124826
            108-1236            BC038552.1         1-1129
FEATURES             Location/Qualifiers
     source          1..1236
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 34.15 cM"
     gene            1..1236
                     /gene="Kxd1"
                     /gene_synonym="0610030B01Rik; 2810422J05Rik"
                     /note="KxDL motif containing 1"
                     /db_xref="GeneID:75620"
                     /db_xref="MGI:MGI:1922870"
     exon            1..118
                     /gene="Kxd1"
                     /gene_synonym="0610030B01Rik; 2810422J05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            119..243
                     /gene="Kxd1"
                     /gene_synonym="0610030B01Rik; 2810422J05Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             143..676
                     /gene="Kxd1"
                     /gene_synonym="0610030B01Rik; 2810422J05Rik"
                     /note="UPF0459 protein C19orf50 homolog"
                     /codon_start=1
                     /product="kxDL motif-containing protein 1"
                     /protein_id="NP_083642.1"
                     /db_xref="CCDS:CCDS52574.1"
                     /db_xref="GeneID:75620"
                     /db_xref="MGI:MGI:1922870"
                     /translation="MDTPDSASRVFCGRFLSMVNTDDVNAIILAQKNMLDRFEKTNEM
                     LLNFNNLSSVRLQQMSERFMHHTRTLVDMKRDLDSIFRRIRTLKGKLARQHPEAFSHI
                     PEGSFLEDEDEDPIPPSITTTIATSEQSTGSCDTSPDTVSPSLSPGFEDLSHIQPGSP
                     AINGHRQTDDEEETHEE"
     exon            244..396
                     /gene="Kxd1"
                     /gene_synonym="0610030B01Rik; 2810422J05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            397..443
                     /gene="Kxd1"
                     /gene_synonym="0610030B01Rik; 2810422J05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            444..1216
                     /gene="Kxd1"
                     /gene_synonym="0610030B01Rik; 2810422J05Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1192..1197
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Kxd1"
                     /gene_synonym="0610030B01Rik; 2810422J05Rik"
                     /note="hexamer: AATAAA"
     polyA_site      1216
                     /gene="Kxd1"
                     /gene_synonym="0610030B01Rik; 2810422J05Rik"
                     /note="major polyA site"
ORIGIN      
        1 gcggtgagta cgcgcaggct cctaggcgcc aggacagggg gcgctcgtgg acgctctatg
       61 atgacgtaag cgctagggcg ccctcccgga agcgcgagcc aggccgccag atgtgcaggc
      121 attggaggcg gaggagaaag agatggacac cccagactca gcctcaaggg tcttctgtgg
      181 ccgcttcctc agcatggtga acactgatga tgtcaatgcc ataatcctgg cccagaagaa
      241 tatgctggac cgcttcgaga aaaccaacga gatgcttctg aacttcaaca atctgtccag
      301 tgtgcggctg caacagatga gtgagcgctt catgcaccat acccgcacct tggtggacat
      361 gaaacgggat ctggacagca ttttccgaag gatcaggaca ctgaagggga agctagcccg
      421 gcagcaccca gaggccttca gccacatccc agagggttca ttcctagagg atgaagatga
      481 agaccctatc ccacccagta tcaccacaac catcgccacc tcggagcaga gcacgggctc
      541 ctgtgacacc agccctgaca cggtctcgcc atccctaagt cctggctttg aggacctatc
      601 acacattcaa cctggctctc ctgccatcaa cggccacaga cagacagatg atgaggaaga
      661 gacacatgaa gaatagcctc cctcccacca tcccagaaag gctcagggca gccgtgatcc
      721 tcctagggtc acagtcggtc agcttggctg ctccattctt tcataggcag gattcctaat
      781 tcctgccact ccccctaaga gcaggacttc cctatgccag cacatgtgcc ccaggtgggg
      841 ctgagtacag gtaaccttga gctcagcttg ggccagcttt gaacagtgct tctgaggtcc
      901 ccagagacca aagccagatc gtctgtcccc cacaccttag gtgggcacag gagggccgag
      961 cttgtttcta cccactggca gctgctgact caactctggg ctccctgcca tctgtggagt
     1021 acttttttcc tgttgtgttg aatactggag aaatagaagg ttcaagatag aggcagacct
     1081 gactgtttct tgagggtcca tcaggcatct ccaggagctg gccagttatc ttagaaaaca
     1141 actgaatgga atatttttgt acctgatgtt tccagatgtt gggaagttat caataaagac
     1201 tgttgttaaa agggaaaaaa aaaaaaaaaa aaaaaa
//
