LOCUS       NM_001312914            6124 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus kinase suppressor of ras 2 (Ksr2), mRNA.
ACCESSION   NM_001312914 XM_006530392
VERSION     NM_001312914.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6124)
  AUTHORS   Gomez,G.A., Rundle,C.H., Xing,W., Kesavan,C., Pourteymoor,S.,
            Lewis,R.E., Powell,D.R. and Mohan,S.
  TITLE     Contrasting effects of Ksr2, an obesity gene, on trabecular bone
            volume and bone marrow adiposity
  JOURNAL   Elife 11, e82810 (2022)
   PUBMED   36342465
  REMARK    GeneRIF: Contrasting effects of <i>Ksr2</i>, an obesity gene, on
            trabecular bone volume and bone marrow adiposity.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6124)
  AUTHORS   Saul,M.C., Stevenson,S.A., Zhao,C., Driessen,T.M., Eisinger,B.E.
            and Gammie,S.C.
  TITLE     Genomic variants in an inbred mouse model predict mania-like
            behaviors
  JOURNAL   PLoS One 13 (5), e0197624 (2018)
   PUBMED   29768498
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 6124)
  AUTHORS   Li,J., Deng,S.P., Wei,G. and Yu,P.
  TITLE     CITGeneDB: a comprehensive database of human and mouse genes
            enhancing or suppressing cold-induced thermogenesis validated by
            perturbation experiments in mice
  JOURNAL   Database (Oxford) 2018 (2018)
   PUBMED   29688375
REFERENCE   4  (bases 1 to 6124)
  AUTHORS   Guo,L., Costanzo-Garvey,D.L., Smith,D.R., Neilsen,B.K.,
            MacDonald,R.G. and Lewis,R.E.
  TITLE     Kinase Suppressor of Ras 2 (KSR2) expression in the brain regulates
            energy balance and glucose homeostasis
  JOURNAL   Mol Metab 6 (2), 194-205 (2016)
   PUBMED   28180061
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 6124)
  AUTHORS   Guo,L., Costanzo-Garvey,D.L., Smith,D.R., Zavorka,M.E.,
            Venable-Kang,M., MacDonald,R.G. and Lewis,R.E.
  TITLE     Cell non-autonomous regulation of hepatic IGF-1 and neonatal growth
            by Kinase Suppressor of Ras 2 (KSR2)
  JOURNAL   Sci Rep 6, 32093 (2016)
   PUBMED   27561547
  REMARK    GeneRIF: These data indicate that KSR2 functions in a cell
            non-autonomous fashion to regulate GH-stimulated IGF-1 expression
            in the liver of neonatal mice, which plays a key role in the
            development of body length.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 6124)
  AUTHORS   Fernandez,M.R., Henry,M.D. and Lewis,R.E.
  TITLE     Kinase suppressor of Ras 2 (KSR2) regulates tumor cell
            transformation via AMPK
  JOURNAL   Mol Cell Biol 32 (18), 3718-3731 (2012)
   PUBMED   22801368
  REMARK    GeneRIF: KSR2 is essential to tumor cell energy homeostasis and
            critical to the integration of mitogenic and metabolic signaling
            pathways
REFERENCE   7  (bases 1 to 6124)
  AUTHORS   Revelli,J.P., Smith,D., Allen,J., Jeter-Jones,S., Shadoan,M.K.,
            Desai,U., Schneider,M., van Sligtenhorst,I., Kirkpatrick,L.,
            Platt,K.A., Suwanichkul,A., Savelieva,K., Gerhardt,B., Mitchell,J.,
            Syrewicz,J., Zambrowicz,B., Hamman,B.D., Vogel,P. and Powell,D.R.
  TITLE     Profound obesity secondary to hyperphagia in mice lacking kinase
            suppressor of ras 2
  JOURNAL   Obesity (Silver Spring) 19 (5), 1010-1018 (2011)
   PUBMED   21127480
  REMARK    GeneRIF: The metabolic phenotype of KSR2 heterozygous
            (KSR2(+/minus;)) and KSR2(-/-) mice suggests that human KSR2
            variants may contribute to a similar phenotype linked to human
            chromosome 12q24
REFERENCE   8  (bases 1 to 6124)
  AUTHORS   Costanzo-Garvey,D.L., Pfluger,P.T., Dougherty,M.K., Stock,J.L.,
            Boehm,M., Chaika,O., Fernandez,M.R., Fisher,K., Kortum,R.L.,
            Hong,E.G., Jun,J.Y., Ko,H.J., Schreiner,A., Volle,D.J., Treece,T.,
            Swift,A.L., Winer,M., Chen,D., Wu,M., Leon,L.R., Shaw,A.S.,
            McNeish,J., Kim,J.K., Morrison,D.K., Tschop,M.H. and Lewis,R.E.
  TITLE     KSR2 is an essential regulator of AMP kinase, energy expenditure,
            and insulin sensitivity
  JOURNAL   Cell Metab 10 (5), 366-378 (2009)
   PUBMED   19883615
  REMARK    GeneRIF: KSR2 regulates AMPK-dependent glucose uptake and fatty
            acid oxidation in mouse embryonic fibroblasts and glycolysis in a
            neuronal cell line.
REFERENCE   9  (bases 1 to 6124)
  AUTHORS   Dougherty,M.K., Ritt,D.A., Zhou,M., Specht,S.I., Monson,D.M.,
            Veenstra,T.D. and Morrison,D.K.
  TITLE     KSR2 is a calcineurin substrate that promotes ERK cascade
            activation in response to calcium signals
  JOURNAL   Mol Cell 34 (6), 652-662 (2009)
   PUBMED   19560418
  REMARK    GeneRIF: The protein phosphatase calcineurin selectively interacts
            with KSR2 and KSR2 uniquely contributes to Ca2+-mediated ERK
            signaling.
REFERENCE   10 (bases 1 to 6124)
  AUTHORS   Brommage,R., Desai,U., Revelli,J.P., Donoviel,D.B., Fontenot,G.K.,
            Dacosta,C.M., Smith,D.D., Kirkpatrick,L.L., Coker,K.J.,
            Donoviel,M.S., Eberhart,D.E., Holt,K.H., Kelly,M.R., Paradee,W.J.,
            Philips,A.V., Platt,K.A., Suwanichkul,A., Hansen,G.M., Sands,A.T.,
            Zambrowicz,B.P. and Powell,D.R.
  TITLE     High-throughput screening of mouse knockout lines identifies true
            lean and obese phenotypes
  JOURNAL   Obesity (Silver Spring) 16 (10), 2362-2367 (2008)
   PUBMED   18719666
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC113299.14, AK137433.1, BC068233.1 and KJ719253.1.
            
            On Aug 23, 2015 this sequence version replaced XM_006530392.2.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN01164131,
                              SAMN01164132 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-517               AC113299.14        74331-74847
            518-1816            AK137433.1         520-1818
            1817-2348           BC068233.1         602-1133
            2349-3683           KJ719253.1         465-1799
            3684-6124           BC068233.1         2147-4587
FEATURES             Location/Qualifiers
     source          1..6124
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 56.88 cM"
     gene            1..6124
                     /gene="Ksr2"
                     /note="kinase suppressor of ras 2"
                     /db_xref="GeneID:333050"
                     /db_xref="MGI:MGI:3610315"
     exon            1..1007
                     /gene="Ksr2"
                     /inference="alignment:Splign:2.1.0"
     CDS             828..3683
                     /gene="Ksr2"
                     /EC_number="2.7.11.1"
                     /codon_start=1
                     /product="kinase suppressor of Ras 2"
                     /protein_id="NP_001299843.1"
                     /db_xref="GeneID:333050"
                     /db_xref="MGI:MGI:3610315"
                     /translation="MDEENMTKSEEQQPLSLQKALQQCELVQNMIDLSISNLEGLRTK
                     CAASNDLTQKEIRTLESKLVKYFSRQLSCKKKVALQERNAELDGFPQLRHWFRIVDVR
                     KEVLEEISPDQLSLEDLLEMTDEQVCETVEKYGANQEECARLNASLSCLRNVHKSGGN
                     LSKQDWIIQWPTTEPGQESNPVCPPEPSPWIRTHLSQSPRVQTKCPQHFCPTSPTPGT
                     PVYTQVDRLTVDAYPNLCPPPPPLESGHRSLPPSPRQRHVVRTPPRTPNIVTTVTPPG
                     TPPMRRKNKLKPPGTPPPSSRKLIHLIPGFTALHRSKSHEFQLGNRVDEANTPKAKKK
                     SKPLNLKIHSGVGSCENIPAQQRSPLLSERSLRSFFVGHGPFLPSTPPVHTEANFSAN
                     TLSVPRWSPQIPRRDLGNSIKHRFSTKYWMSQTCTVCGKGMLFGLKCKNCKLKCHNKC
                     TKEAPPCHLLIIHRGDPARLVRTESVPCDINNPVRKPARYSDLHISQTLPKTNKINKD
                     HIPVPYQPDSSSNPSSTTSSTPSSPAPPLPPSATPPSPLHPSPQCPRQKKNFNLPASH
                     YYKYKQQFIFPDVVPVPETPTRAPQVILHPVTSNTILEGNPLLQIEVEPTSENEESHN
                     EAEESEDEFEEMNLSLLSARSFPRKASQTSIFLQEWDIPFEQLEIGELIGKGRFGQVY
                     HGRWHGEVAIRLIDIERDNEDQLKAFKREVMAYRQTRHENVVLFMGACMSPPHLAIIT
                     SLCKGRTLYSVVRDAKIVLDVNKTRQIAQEIVKGMGYLHAKGILHKDLKSKNVFYDNG
                     KVVITDFGLFSISGVLQAGRRDDKLRIQNGWLCHLAPEIIRQLSPDTEEDKLPFSKHS
                     DVFALGTIWYELHAREWPFKTQPAEAIIWQMGTGMKPNLSQIGMGKEISDILLFCWAF
                     EQEERPTFTKLMDMLEKLPKRNRRLSHPGHFWKSAEL"
     exon            1008..1148
                     /gene="Ksr2"
                     /inference="alignment:Splign:2.1.0"
     exon            1149..1299
                     /gene="Ksr2"
                     /inference="alignment:Splign:2.1.0"
     exon            1300..1816
                     /gene="Ksr2"
                     /inference="alignment:Splign:2.1.0"
     exon            1817..2001
                     /gene="Ksr2"
                     /inference="alignment:Splign:2.1.0"
     exon            2002..2071
                     /gene="Ksr2"
                     /inference="alignment:Splign:2.1.0"
     exon            2072..2155
                     /gene="Ksr2"
                     /inference="alignment:Splign:2.1.0"
     exon            2156..2223
                     /gene="Ksr2"
                     /inference="alignment:Splign:2.1.0"
     exon            2224..2348
                     /gene="Ksr2"
                     /inference="alignment:Splign:2.1.0"
     exon            2349..2517
                     /gene="Ksr2"
                     /inference="alignment:Splign:2.1.0"
     exon            2518..2559
                     /gene="Ksr2"
                     /inference="alignment:Splign:2.1.0"
     exon            2560..2632
                     /gene="Ksr2"
                     /inference="alignment:Splign:2.1.0"
     exon            2633..2681
                     /gene="Ksr2"
                     /inference="alignment:Splign:2.1.0"
     exon            2682..3049
                     /gene="Ksr2"
                     /inference="alignment:Splign:2.1.0"
     exon            3050..3146
                     /gene="Ksr2"
                     /inference="alignment:Splign:2.1.0"
     exon            3147..3280
                     /gene="Ksr2"
                     /inference="alignment:Splign:2.1.0"
     exon            3281..3412
                     /gene="Ksr2"
                     /inference="alignment:Splign:2.1.0"
     exon            3413..3542
                     /gene="Ksr2"
                     /inference="alignment:Splign:2.1.0"
     exon            3543..3676
                     /gene="Ksr2"
                     /inference="alignment:Splign:2.1.0"
     exon            3677..6116
                     /gene="Ksr2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4135..4140
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ksr2"
                     /note="hexamer: AATACA"
     polyA_site      4159
                     /gene="Ksr2"
                     /note="major polyA site"
ORIGIN      
        1 aggcaagatg tcggtgtgga gcgaggcagg agcgatttca gcagccgtcc cccctggagc
       61 ccggcggcgg caacagcagc aacggcgaca gtggcaacag cagcagcagg agcagcagca
      121 gcagcgttgt cgcggggagc agaccgcagc cagccgcagt gggcgccgca gccgcgccag
      181 ccgtgcgcac agcatcccga gagcgcgctg agcgcgggga cccgcggacc atgccgtgtc
      241 accgcgacca ggaggggggc aggcgcgctc ctttttgaca taaaagccag cccggccaaa
      301 tagatttata tacatataat tccgcccttc acggagccgg tgtgcgaagc gtgagctcta
      361 tttccctctg cctcctcctt ccacttctcc tcctcccctt cctcctcctc ctcctcctct
      421 ttctcctcct ctttctcctc ctcctctcta agtgtacaga ctgcacccta ccacctggtt
      481 ggcttctgac aaacgggcat ctctcccttt ttagggacca gagacacaga gaaagagaga
      541 ggagagagga gacaagggac attctaatgc agactgcctg atactctccc ccgccccaaa
      601 taataataaa ttttggctct tgtcccctcc tccacccccc actcccctca agcttgtgtg
      661 agatgttggg tttcttcagg agacaccgct gagaagtcgc agaggttggg gaggcgtagg
      721 gggggtgggg gtggactccc tctacctcta ctccttccct cccccttttt ttctttctgg
      781 gaggaggtgg aggaggagga ggggaagggg gggttgcaga gcaagcgatg gatgaggaaa
      841 acatgacgaa aagcgaagag cagcaacctc tgagtttgca aaaagccttg cagcagtgcg
      901 agttggttca gaacatgatc gacctgagca tctccaatct ggaagggctt aggaccaagt
      961 gtgcagcttc caacgacctc acgcagaagg agatcaggac cctggagagc aagctggtga
     1021 agtacttcag ccgacagctg tcctgcaaga agaaggtggc tctgcaggaa cgcaatgctg
     1081 aactggacgg cttcccccag ctccgccact ggttccggat cgtggatgtc cgaaaggaag
     1141 tcctggagga gatctcccct gaccagctga gcttggagga cctcctggag atgaccgacg
     1201 agcaggtgtg tgagaccgtg gagaagtatg gagccaacca ggaagagtgc gcccggctca
     1261 acgcctcact ctcctgcctc aggaatgtgc acaaatcagg agggaatctc tccaaacaag
     1321 attggatcat ccagtggccc accacggagc cagggcagga gagcaaccct gtgtgccccc
     1381 cggagcccag cccgtggatc cgaacccacc tctcccagag ccccagggtc cagaccaagt
     1441 gtccccagca cttctgtcct accagcccta cgcctgggac ccctgtgtac acccaagtgg
     1501 acagactcac tgtagatgcc tacccgaact tgtgcccgcc gccgccaccc ctggaatcag
     1561 gccaccgctc tctgcccccg tctccccggc agcggcacgt agtccgcacc ccacctcgca
     1621 ccccaaatat tgtcaccacc gtgaccccac ctggcacgcc acccatgagg agaaaaaaca
     1681 agctgaagcc tcccgggacg ccacccccct cctctcggaa gctcatccat ctgatccctg
     1741 gcttcacagc gctgcacagg agcaaatccc acgagttcca gctcgggaac cgtgtagacg
     1801 aggccaacac acccaaagcc aagaagaaga gcaaaccctt gaacctcaag atccacagcg
     1861 gcgtgggcag ctgcgagaac atccccgccc agcaacgctc tccgctcctg tccgagcgct
     1921 ccttgcggtc cttctttgtg ggccacgggc ccttcctgcc ctccacccca cctgtccaca
     1981 ctgaagccaa tttctctgca aacacactct ctgtacctcg ctggtcacca cagatcccac
     2041 gcagagacct tggcaattcc atcaagcaca ggttttccac caagtactgg atgtctcaga
     2101 cgtgcacggt ctgcgggaaa gggatgcttt ttggcctcaa gtgtaaaaac tgcaagttaa
     2161 agtgccacaa taaatgcacc aaagaagccc cgccctgtca cctcctgatt atccaccgag
     2221 gagacccagc aaggttagtg cgaacggagt cggtgccctg tgacatcaac aacccggtcc
     2281 ggaagcctgc ccgatattca gatctccaca tcagtcagac tctccccaaa accaacaaaa
     2341 tcaacaagga ccacatccct gtcccttacc agccagactc cagcagcaat ccctcctcca
     2401 cgacgtcctc cacgccctcc tcaccggcac cccccctccc tcccagcgcc acgccgcctt
     2461 ctcccctgca cccctccccg cagtgcccga gacagaaaaa gaacttcaac ctgccagctt
     2521 cccactacta caaatacaag caacagttca tcttcccaga tgtggtgcct gtaccagaga
     2581 cacccacccg ggcaccccaa gtcatcctgc atcctgtcac ctcaaataca atcttggaag
     2641 gaaacccatt acttcaaatt gaagtggaac caacctccga gaacgaagag agccacaatg
     2701 aagcagagga gtccgaggac gagtttgaag agatgaacct atccctcctc tcagcccgga
     2761 gcttcccacg caaagccagc cagaccagca tcttccttca ggagtgggac atcccgtttg
     2821 aacagctaga gattggcgag ctcatcggga agggtcgctt cgggcaggtt taccacggac
     2881 gctggcacgg cgaggtggcc atccggttga ttgacataga gagggacaat gaggaccagc
     2941 ttaaggcctt caagcgggaa gtgatggcct acaggcagac gaggcacgag aacgtggtgc
     3001 tcttcatggg agcctgcatg agcccacccc acttggccat catcaccagc ctctgtaagg
     3061 gacggacact ctactctgtg gtgagggacg ccaagattgt cttggatgtc aacaaaacca
     3121 ggcagatcgc gcaagagatt gtaaagggca tgggctacct ccacgccaag gggatccttc
     3181 ataaggacct caaatcgaag aacgtcttct atgacaacgg caaagtggtc atcacagact
     3241 ttgggctctt cagcatttcc ggggtgctgc aggctggccg gcgggacgac aaactgcgga
     3301 tccagaacgg ctggctgtgt cacctggccc cagaaatcat ccgccagctg tcccctgaca
     3361 cagaagagga caagctccca ttctccaagc actcggatgt ctttgcgctt ggcaccatct
     3421 ggtatgagct ccacgccagg gagtggccat tcaagaccca accagcagag gcaatcattt
     3481 ggcagatggg cacgggaatg aagcccaacc tcagccagat tggcatggga aaagaaatct
     3541 cggacatact gctcttctgc tgggccttcg agcaggaaga gcggcccacc tttaccaagc
     3601 tcatggacat gctagagaaa ctgccaaagc gaaaccgccg cctgtcgcac cccggacatt
     3661 tctggaagtc tgcagagctg tgaccatggc cagcatcagc tgcctcaccc ccaaaccgcc
     3721 tctgtaaccc tgctctgccc tctgccagct caggaggccc aggctcactg tcagggagtc
     3781 ctgactcggc tcagcctggg agacctgtgt gatgacgtca cagaggctgt ccacaccttc
     3841 gacttgtacc ccgttactca ggcacgatca gggaccactc aactaggacc aaactgggcc
     3901 agagagggtc ccatgtgtgg tgtgaaggag ccacagactg agcacaccac ctcggactgt
     3961 ggagaccaag acacatgccc agtgggcaga ctcagactca cacgctggac cagtgtgtgc
     4021 gcatgtgtct acacatggac agggccaact gctatccttc tgcctggacg agccagctgt
     4081 ggagtgtccc agctgtgcta tcctggaaca cagaaccagg atggaaccag aaacaataca
     4141 cctgctccgt tgtcaaggct tctaggccaa ggtcagggta gggaggtggg gtgggttaaa
     4201 cttgcaaaca tctgatttta gaggtcccat tccaagatgg aagtcaccgg ttgccgctga
     4261 gcacacaatt ctgaaggaca gtaggcagtc ctgcaggtct tttttagcac agggcctctc
     4321 tggggaccag tccctggcct tcacccttct cccattttgt aagaacactg ttctaactca
     4381 cctcatgccc acgctaccct gggcaactgg agaacaccat agcgtttcag ctgatgtgac
     4441 atttggtgtg acctttacca gttcaccatc attcatggct tcccccaaag tcccgagtcc
     4501 tgagaaccgg ggctgtggca agagagttct ggtgtgttct ctctgtgggg ctagcaatgc
     4561 cggggttaag ttctccctcg gtgatggaga cggtcctggg tatgcatgat gggttacatg
     4621 ggtgtgtgtg tgtgtgtaac tgtttacaat ggtctccctg cctctcacgg gctgtgttcc
     4681 aggagaatgc acatagagag gttctgtggt ctctgctgtc gcctggtgct gaatcctgag
     4741 tggtttcccc actgaggacc ctgtgaccct gtgacccttg gcccctccct tattgtgcac
     4801 actcagcacc ccatcttcca agcctttctt catcccccac cttcttttgg gaaggggtgg
     4861 cacagagtga atgggaagga gagccctgag gtcactggtc cacatgccca aagccatgcc
     4921 ccccagtgat cagacctgac acaagaggca aagctgtccc taagcagaga attagcaggg
     4981 ttagccagac agcaaaatcc atgtaaacat acaaaaccac cccccctttt tgagtggccc
     5041 tattggatgt acacactagg accaagcacg ggtccaaagc aggaagactg attgacagta
     5101 gtcacacttc tagagagatg taccccatga cactttcaag tcttttcaga accttctcac
     5161 ccctttgcaa agctcttgcc gtctgcaccc gggaccccgg gacccacaca agttgtcccc
     5221 atgtgaacat cctgcctctc ctggtgacat ctgtctctgg ctcagcttct ctgcctctta
     5281 cagacagttt ccctgtacat ttgcttatgg ccctgggctc cagagtcgct gaagaccact
     5341 ctccacagca gctgtaaccc catctaacaa gccctgttct ggatatatct ctgtggccag
     5401 ggctggactg agactgaccc cctcctacta agcatcttag agtttctctt ttctctttaa
     5461 ttgcatcagg acccctttgg tccatgtacc ccggtctctg tcacatgcct ttgtatcttg
     5521 gaggaagtaa gagaggagag agccagggag ggctgaagct ctgggaccct gaagtgtccc
     5581 ccgggaactg ggactcactc atcttctcct gtttgtagct caatgaccca gtgggtcaca
     5641 gttctaggcg ctccaaggaa gccaggggag ggggactcct caggaaggag tgaccagtca
     5701 cctgcctccc agggttctgc cttgccctta agctagggtc cttcaagcat ccacagactt
     5761 agagtgtggt ggtaacatgc ttgtaatcct ggcactctgg aggctgaggc aggaggataa
     5821 caagtctaga ctatatatga tttctgaggg tctgttagtg aataagtacc tggatgacat
     5881 gggacaagtc ccagccttcc ctgctcctgc gctgctcttc ctcttatggg atagggtcta
     5941 ggtcaaatgt cacctcttca ctcttgctct ttcctgacct ccatgcccac cgagacctgg
     6001 gcctgggctg caggcttcat ccctcactga cttccctccc cccttcagct acaggccctg
     6061 ccttgctagt aacctcttaa tgtacagaca tctggatcaa gggattaaaa aaaaaaaaaa
     6121 aaaa
//
