LOCUS       NM_010675                579 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus keratin associated protein 8-1 (Krtap8-1), mRNA.
ACCESSION   NM_010675 XM_917709
VERSION     NM_010675.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 579)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 579)
  AUTHORS   Wu,D.D., Irwin,D.M. and Zhang,Y.P.
  TITLE     Molecular evolution of the keratin associated protein gene family
            in mammals, role in the evolution of mammalian hair
  JOURNAL   BMC Evol Biol 8, 241 (2008)
   PUBMED   18721477
  REMARK    Erratum:[BMC Evol Biol. 2009;9:213]
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 579)
  AUTHORS   Habtezion,A., Toivola,D.M., Butcher,E.C. and Omary,M.B.
  TITLE     Keratin-8-deficient mice develop chronic spontaneous Th2 colitis
            amenable to antibiotic treatment
  JOURNAL   J Cell Sci 118 (Pt 9), 1971-1980 (2005)
   PUBMED   15840656
  REMARK    GeneRIF: Keratin-8 has a role in development of chronic spontaneous
            Th2 colitis
REFERENCE   4  (bases 1 to 579)
  AUTHORS   Pruett,N.D., Tkatchenko,T.V., Jave-Suarez,L., Jacobs,D.F.,
            Potter,C.S., Tkatchenko,A.V., Schweizer,J. and Awgulewitsch,A.
  TITLE     Krtap16, characterization of a new hair keratin-associated protein
            (KAP) gene complex on mouse chromosome 16 and evidence for
            regulation by Hoxc13
  JOURNAL   J Biol Chem 279 (49), 51524-51533 (2004)
   PUBMED   15385554
  REMARK    GeneRIF: Krtap16 is a hair keratin-associated protein gene complex
            regulated by Hoxc13; localized to chromosome 16
REFERENCE   5  (bases 1 to 579)
  AUTHORS   Aoki,N., Ito,K. and Ito,M.
  TITLE     Isolation and characterization of mouse high-glycine/tyrosine
            proteins
  JOURNAL   J Biol Chem 272 (48), 30512-30518 (1997)
   PUBMED   9374545
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK133727.1 and AC140433.3.
            
            On Jul 23, 2009 this sequence version replaced XM_917709.3.
            
            ##Evidence-Data-START##
            Transcript is intronless :: CJ048447.1, AK133727.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-572               AK133727.1         2-573
            573-579             AC140433.3         91825-91831
FEATURES             Location/Qualifiers
     source          1..579
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="16"
                     /map="16 51.42 cM"
     gene            1..579
                     /gene="Krtap8-1"
                     /note="keratin associated protein 8-1"
                     /db_xref="GeneID:16703"
                     /db_xref="MGI:MGI:1330293"
     exon            1..579
                     /gene="Krtap8-1"
                     /inference="alignment:Splign:2.1.0"
     CDS             46..231
                     /gene="Krtap8-1"
                     /note="HGT keratin; HGTp type I F; high-glycine/tyrosine
                     protein keratin; keratin-associated protein 8.1; HGTpI F"
                     /codon_start=1
                     /product="keratin-associated protein 8-1"
                     /protein_id="NP_034805.1"
                     /db_xref="CCDS:CCDS49901.1"
                     /db_xref="GeneID:16703"
                     /db_xref="MGI:MGI:1330293"
                     /translation="MYYTGAEGSVFPGCYWGSYGYPLGYSVGCGYGSTYSPVGYGLGY
                     GYNGCGAYRRYWPFALY"
     regulatory      549..554
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Krtap8-1"
                     /note="hexamer: AATAAA"
     polyA_site      575
                     /gene="Krtap8-1"
                     /note="major polyA site"
ORIGIN      
        1 atcacactca cttccctcct acctaagcct tccactcctg acatcatgta ctacaccggc
       61 gctgagggct ctgtcttccc aggatgctac tggggcagct atggctaccc tctggggtac
      121 agtgttggct gtggctatgg tagcacctac tctccagttg gctatggcct tggctatggc
      181 tacaatggct gcggggctta cagaagatac tggccatttg ctctctactg atttgctgtg
      241 atcccccagg cacagttcca tctcttcatg aaggctttgt gacacctcca ggttccagcc
      301 tcaccaccct tcatcttcct ttcttcatca acctcttcca agaagctgtt tttcagatct
      361 tacaactgag tctcaagcaa aggaactgaa aatctagatg atgccttact ctgcctttcc
      421 tggatgctct ttctttagga ctttttcaga agcttggcaa cccatgtggc acgtattgct
      481 ttggaatatt tcaagactct catgattccc tgttatggtg aagttgtgga tgtgtctgtc
      541 aaattctcaa taaatttgtc tgagcttgca taacatttc
//
