LOCUS       NM_010676                482 bp    mRNA    linear   ROD 27-JUL-2024
DEFINITION  Mus musculus keratin associated protein 19-5 (Krtap19-5), mRNA.
ACCESSION   NM_010676
VERSION     NM_010676.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Wu,D.D., Irwin,D.M. and Zhang,Y.P.
  TITLE     Molecular evolution of the keratin associated protein gene family
            in mammals, role in the evolution of mammalian hair
  JOURNAL   BMC Evol Biol 8, 241 (2008)
   PUBMED   18721477
  REMARK    Erratum:[BMC Evol Biol. 2009;9:213]
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Pruett,N.D., Tkatchenko,T.V., Jave-Suarez,L., Jacobs,D.F.,
            Potter,C.S., Tkatchenko,A.V., Schweizer,J. and Awgulewitsch,A.
  TITLE     Krtap16, characterization of a new hair keratin-associated protein
            (KAP) gene complex on mouse chromosome 16 and evidence for
            regulation by Hoxc13
  JOURNAL   J Biol Chem 279 (49), 51524-51533 (2004)
   PUBMED   15385554
  REMARK    GeneRIF: Krtap16 is a hair keratin-associated protein gene complex
            regulated by Hoxc13; localized to chromosome 16
REFERENCE   3  (bases 1 to 482)
  AUTHORS   Tkatchenko,A.V., Visconti,R.P., Shang,L., Papenbrock,T.,
            Pruett,N.D., Ito,T., Ogawa,M. and Awgulewitsch,A.
  TITLE     Overexpression of Hoxc13 in differentiating keratinocytes results
            in downregulation of a novel hair keratin gene cluster and alopecia
  JOURNAL   Development 128 (9), 1547-1558 (2001)
   PUBMED   11290294
REFERENCE   4  (bases 1 to 482)
  AUTHORS   Aoki,N., Ito,K. and Ito,M.
  TITLE     Isolation and characterization of mouse high-glycine/tyrosine
            proteins
  JOURNAL   J Biol Chem 272 (48), 30512-30518 (1997)
   PUBMED   9374545
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            D86422.1 and AA717139.1.
            
            On Aug 31, 2006 this sequence version replaced NM_010676.1.
            
            Sequence Note: This gene product, Krtap8-2, is novel and a protein
            has been predicted.
            
            ##Evidence-Data-START##
            Transcript is intronless :: D86422.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-169               D86422.1           12-180
            170-171             AA717139.1         178-179
            172-361             D86422.1           183-372
            362-362             AA717139.1         369-369
            363-482             D86422.1           373-492
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="16"
                     /map="16 51.42 cM"
     gene            1..482
                     /gene="Krtap19-5"
                     /gene_synonym="Krtap8-2"
                     /note="keratin associated protein 19-5"
                     /db_xref="GeneID:16704"
                     /db_xref="MGI:MGI:1330295"
     exon            1..482
                     /gene="Krtap19-5"
                     /gene_synonym="Krtap8-2"
                     /inference="alignment:Splign:2.1.0"
     CDS             28..216
                     /gene="Krtap19-5"
                     /gene_synonym="Krtap8-2"
                     /note="HGTp type 1 alpha; keratin associated protein 8-2;
                     glycine tyrosine-rich hair protein; high-glycine tyrosine
                     keratin type 1 alpha; keratin-associated protein 8.2;
                     HGTpI alpha"
                     /codon_start=1
                     /product="keratin-associated protein 19-5"
                     /protein_id="NP_034806.2"
                     /db_xref="CCDS:CCDS37388.1"
                     /db_xref="GeneID:16704"
                     /db_xref="MGI:MGI:1330295"
                     /translation="MSYYGSYYGGLGSGIRGFGNLGYGYGCGCGFGGYGYGSGYGRYG
                     YGYRRPLYYGGYGFSRFY"
     regulatory      465..470
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Krtap19-5"
                     /gene_synonym="Krtap8-2"
ORIGIN      
        1 caaaccataa ctaccagtct tgacaccatg agctactacg gcagctacta cggaggtctg
       61 ggctctggca tccgaggctt tgggaacctg ggttatggct atggctgtgg ctgtggcttt
      121 ggaggttacg gatatggatc tggctatggc agatatggat atggctaccg ccgccccctt
      181 tattatggag gatatggatt ctcccgattc tactgaaatg cattccagag gagccagcat
      241 cttaaatatg aaaacattac ccctaactca tactaggaca aaattaaacg aacatactga
      301 ctgtgaatca agtcaagaag aaaacaattt aacgtgtaag actttcagac aaccatttaa
      361 cacgtaagac gtcgagacca tgcttatcat cgtataattc tccatattat gcccccttac
      421 ttctcttctg tcatgtcata aatgtagact ttttgatctt ttgcaataaa ttaccctaac
      481 tt
//
