LOCUS       NM_177717               2534 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus keratin 90 (Krt90), mRNA.
ACCESSION   NM_177717
VERSION     NM_177717.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2534)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2534)
  AUTHORS   Sundberg,J.P., Galantino-Homer,H., Fairfield,H., Ward-Bailey,P.F.,
            Harris,B.S., Berry,M., Pratt,C.H., Gott,N.E., Bechtold,L.S.,
            Kaplan,P.R., Durbin-Johnson,B.P., Rocke,D.M. and Rice,R.H.
  TITLE     Witch Nails (Krt90whnl): A spontaneous mouse mutation affecting
            nail growth and development
  JOURNAL   PLoS One 17 (11), e0277284 (2022)
   PUBMED   36374931
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2534)
  AUTHORS   Fairfield,H., Srivastava,A., Ananda,G., Liu,R., Kircher,M.,
            Lakshminarayana,A., Harris,B.S., Karst,S.Y., Dionne,L.A.,
            Kane,C.C., Curtain,M., Berry,M.L., Ward-Bailey,P.F., Greenstein,I.,
            Byers,C., Czechanski,A., Sharp,J., Palmer,K., Gudis,P., Martin,W.,
            Tadenev,A., Bogdanik,L., Pratt,C.H., Chang,B., Schroeder,D.G.,
            Cox,G.A., Cliften,P., Milbrandt,J., Murray,S., Burgess,R.,
            Bergstrom,D.E., Donahue,L.R., Hamamy,H., Masri,A., Santoni,F.A.,
            Makrythanasis,P., Antonarakis,S.E., Shendure,J. and Reinholdt,L.G.
  TITLE     Exome sequencing reveals pathogenic mutations in 91 strains of mice
            with Mendelian disorders
  JOURNAL   Genome Res 25 (7), 948-957 (2015)
   PUBMED   25917818
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK028791.1 and AC103674.10.
            
            On Nov 25, 2009 this sequence version replaced NM_177717.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK028791.1, BC118024.1 [ECO:0000332]
            RNAseq introns              :: partial sample support SAMN00849374,
                                           SAMN00849382 [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1584              AK028791.1         2-1585
            1585-1585           AC103674.10        124539-124539       c
            1586-2534           AK028791.1         1587-2535
FEATURES             Location/Qualifiers
     source          1..2534
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="15"
                     /map="15 56.9 cM"
     gene            1..2534
                     /gene="Krt90"
                     /gene_synonym="4732456N10Rik; Ket90"
                     /note="keratin 90"
                     /db_xref="GeneID:239673"
                     /db_xref="MGI:MGI:3045312"
     exon            1..605
                     /gene="Krt90"
                     /gene_synonym="4732456N10Rik; Ket90"
                     /inference="alignment:Splign:2.1.0"
     CDS             126..1742
                     /gene="Krt90"
                     /gene_synonym="4732456N10Rik; Ket90"
                     /codon_start=1
                     /product="uncharacterized protein LOC239673"
                     /protein_id="NP_808385.2"
                     /db_xref="CCDS:CCDS27855.1"
                     /db_xref="GeneID:239673"
                     /db_xref="MGI:MGI:3045312"
                     /translation="MTQRSSVTIKSGGTRNFSASSASLLPGCRPGFSSVSVSQSGKSF
                     GGGIGGGFGTRSLHSFGGNKRISIGGGYRSTRASFGGAACGLGVSGIGYRVGGAYGGY
                     GYGGGMAPGAGGIHEVTVNQSLLTPLHLEIDPSLQRVRKEEKEQIKTLNNKFASFIDK
                     VRFLEQQNKVLETKWSLLQEHKTTRTNLEPMFEAYITNLRRQLECLGGERSRLETELK
                     SMQDVVEDFKNKYEEEIHRRTAAENEFVVLKKDVDAAYMNKVELEAKVEALMDEINFL
                     RAFFEAELAQLQAQISETSVVLSMDNNRSLNLDSIIAEVKAQYEDIANRSRAEAESWY
                     QTKYEELQRSAGQRGDDLRTTKMEISELNRAMQRLRSEIDNLKKQCATLQASIADAEQ
                     RGELALKDAKNKLAELEDALQKAKQDMARQLREYQELMNVKLALDIEIATYRKLLEGE
                     ECRLTGEGVGAVNISVVSSSGGTGYSGGGGLCVSGGGYSGGGYSGSGLCYGGGGSGGF
                     SSTSGRSVSGSSSSMRIVSKTSSTKKSYRS"
     exon            606..814
                     /gene="Krt90"
                     /gene_synonym="4732456N10Rik; Ket90"
                     /inference="alignment:Splign:2.1.0"
     exon            815..875
                     /gene="Krt90"
                     /gene_synonym="4732456N10Rik; Ket90"
                     /inference="alignment:Splign:2.1.0"
     exon            876..971
                     /gene="Krt90"
                     /gene_synonym="4732456N10Rik; Ket90"
                     /inference="alignment:Splign:2.1.0"
     exon            972..1136
                     /gene="Krt90"
                     /gene_synonym="4732456N10Rik; Ket90"
                     /inference="alignment:Splign:2.1.0"
     exon            1137..1262
                     /gene="Krt90"
                     /gene_synonym="4732456N10Rik; Ket90"
                     /inference="alignment:Splign:2.1.0"
     exon            1263..1483
                     /gene="Krt90"
                     /gene_synonym="4732456N10Rik; Ket90"
                     /inference="alignment:Splign:2.1.0"
     exon            1484..1518
                     /gene="Krt90"
                     /gene_synonym="4732456N10Rik; Ket90"
                     /inference="alignment:Splign:2.1.0"
     exon            1519..2534
                     /gene="Krt90"
                     /gene_synonym="4732456N10Rik; Ket90"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 actctggcca agcccagttc ttgaaaggga ttaaaactcg aggtgagccc aggcaagcta
       61 gactccgaag gctctccact cttgccattc ttttgctcca ctgacctttg acaacgactt
      121 ccaccatgac ccagcgatcc tcggtgacca tcaagtctgg gggcacgcgg aacttcagtg
      181 cctcctcggc tagcctcctt cctggatgtc ggccgggttt cagctctgtc tctgtgtccc
      241 agagcgggaa gagtttcgga ggtggcatag ggggtggttt tgggacaaga agcctacaca
      301 gctttggggg taacaagagg atctccatcg gtgggggcta ccgctccacc cgagccagct
      361 ttgggggcgc tgcctgtggt ctgggtgtca gcggcatagg atacagagtt gggggagcct
      421 atggagggta tggatatgga ggtggaatgg cccctggagc tggaggcatc catgaagtca
      481 ctgtcaacca gagtctcctg acacccctcc acctggagat tgatccatct ctccagcggg
      541 ttcgaaagga ggagaaggag cagatcaaga ccctcaacaa caagttcgcc tccttcatag
      601 ataaggtgcg gttcttggag cagcagaaca aagtcttaga gaccaaatgg agcctcctcc
      661 aagagcacaa aacaaccagg accaatctag agcccatgtt cgaagcctac atcaccaacc
      721 tgaggcgcca gctggagtgc ctgggagggg agcggagcag gctggagacg gagctgaaga
      781 gcatgcagga cgtggtggag gacttcaaga acaagtacga agaggaaatc cacagacgta
      841 cagcggcaga gaatgagttt gtggtactca aaaaagatgt ggacgctgcc tacatgaaca
      901 aggtggagct agaggccaag gtggaagctc tgatggatga gatcaacttc ctgagagctt
      961 tctttgaagc ggagctggct caacttcagg ctcaaatctc tgagacctct gtggtcctgt
     1021 ccatggacaa caaccgcagc ctgaacctgg acagcatcat tgctgaggtc aaggcccaat
     1081 acgaggacat tgccaatcgc agccgggcag aggctgaatc ctggtaccag accaagtatg
     1141 aggagctgca gaggtctgct ggccaacgcg gggatgacct ccgtactact aagatggaga
     1201 tctctgagct gaaccgggcc atgcagaggc tgcgttctga gattgacaat ctgaagaagc
     1261 agtgtgccac actccaggct tccattgccg atgccgagca acgcggggag ctggctctca
     1321 aagatgccaa gaacaagctg gccgagctgg aggatgccct gcagaaggcc aagcaggaca
     1381 tggcccgtca actgcgagag taccaggagc tcatgaacgt caagctggcc ctggacatag
     1441 agatcgccac ctaccgaaag ctgctggagg gcgaggagtg caggctcact ggagaaggtg
     1501 ttggtgccgt gaacatctct gtggtctctt cctccggggg cacaggctac agtggaggtg
     1561 gtggcctgtg tgtgagtggc ggaggctaca gcggaggcgg ctacagtggg agtggcctct
     1621 gctacggggg cggaggcagc ggaggtttta gctccaccag cggtcgcagc gtgagcggca
     1681 gcagttcaag catgagaatt gtctccaaga catcatccac caagaagagt taccggagct
     1741 aaagtaccac tcgtcttggc actgtccccg ggcccccatc tccccagcac taaggcctga
     1801 tgcttagccc atgcccgcag tccccagcaa gaggaacaga taccaagtgg cctgtgagtt
     1861 ttaaggttat catccttctg cctccaggca ggtctccaca gagatacccc acccattctt
     1921 gatctcaaag tcctccccta cccacacaga ctcaactgcc ctaggctaca cctttcccct
     1981 taagcagtag ggaagtgcag aaagtccttc gcaatctgtt tggaccctgc aaccacaaga
     2041 ggctctcagt ccttcatggg aactttaaac ttgaccttgg tggcccaaag tcacctttct
     2101 ttgattctcg actcctgagt gactctgagc tgtgaggacc atgcatccct tgtcctggct
     2161 aaaagaagac tctctaatcc ctcaaggcag agccagtcag agaaaggcag atctttgctg
     2221 cttactcttg ctccagggac acagggacac tcctgtttgc acagagggag tgtgaggtta
     2281 taggaaggaa ttgcacggag gtttgtggaa cctggtcttc acagtggttt agtctgaagg
     2341 gttgtgagtc ctcaaatacc tgctacgagt tcaagaacaa agtacttccc aaaggcagtt
     2401 ggtccgtcgt ctgctgtgcc gtgtgaacag aaagttaaca gcttcggagt agcagccaaa
     2461 cctcccaagc tgtccgctcc tctcatgcat gcctatttcc taaaactgct gcaataaaat
     2521 gtcactgagc accc
//
