LOCUS       NM_213730               3193 bp    mRNA    linear   ROD 04-AUG-2024
DEFINITION  Mus musculus keratin 39 (Krt39), mRNA.
ACCESSION   NM_213730 XM_110981
VERSION     NM_213730.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3193)
  AUTHORS   Sotiropoulou,P.A., Karambelas,A.E., Debaugnies,M., Candi,A.,
            Bouwman,P., Moers,V., Revenco,T., Rocha,A.S., Sekiguchi,K.,
            Jonkers,J. and Blanpain,C.
  TITLE     BRCA1 deficiency in skin epidermis leads to selective loss of hair
            follicle stem cells and their progeny
  JOURNAL   Genes Dev 27 (1), 39-51 (2013)
   PUBMED   23271346
REFERENCE   2  (bases 1 to 3193)
  AUTHORS   Schweizer,J., Bowden,P.E., Coulombe,P.A., Langbein,L., Lane,E.B.,
            Magin,T.M., Maltais,L., Omary,M.B., Parry,D.A., Rogers,M.A. and
            Wright,M.W.
  TITLE     New consensus nomenclature for mammalian keratins
  JOURNAL   J Cell Biol 174 (2), 169-174 (2006)
   PUBMED   16831889
REFERENCE   3  (bases 1 to 3193)
  AUTHORS   Hesse,M., Zimek,A., Weber,K. and Magin,T.M.
  TITLE     Comprehensive analysis of keratin gene clusters in humans and
            rodents
  JOURNAL   Eur J Cell Biol 83 (1), 19-26 (2004)
   PUBMED   15085952
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL591417.9.
            
            On Jun 21, 2019 this sequence version replaced NM_213730.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC119541.1, BK004022.1 [ECO:0000332]
            RNAseq introns              :: partial sample support SAMN00849384
                                           [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-533               AL591417.9         91449-91981
            534-616             AL591417.9         92896-92978
            617-773             AL591417.9         93614-93770
            774-935             AL591417.9         94407-94568
            936-1061            AL591417.9         94674-94799
            1062-1282           AL591417.9         96102-96322
            1283-3193           AL591417.9         97917-99827
FEATURES             Location/Qualifiers
     source          1..3193
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 62.92 cM"
     gene            1..3193
                     /gene="Krt39"
                     /gene_synonym="4732494G06Rik; Ka35"
                     /note="keratin 39"
                     /db_xref="GeneID:237934"
                     /db_xref="MGI:MGI:3588208"
     exon            1..533
                     /gene="Krt39"
                     /gene_synonym="4732494G06Rik; Ka35"
                     /inference="alignment:Splign:2.1.0"
     CDS             81..1529
                     /gene="Krt39"
                     /gene_synonym="4732494G06Rik; Ka35"
                     /note="type I hair keratin KA35; ortholog of type I hair
                     keratin KA35; K39; CK-39; cytokeratin-39"
                     /codon_start=1
                     /product="keratin, type I cytoskeletal 39"
                     /protein_id="NP_998895.2"
                     /db_xref="CCDS:CCDS25383.1"
                     /db_xref="GeneID:237934"
                     /db_xref="MGI:MGI:3588208"
                     /translation="MDTKGSTVTISSSTPPQNCSGNTNFRTNSSSNKSCCHDGQSTGC
                     ALQTPQGQGCGSSPCLYRCPHYLIRTYSFHPCLDDGSRCTEGINTHEKETMQILNERL
                     ANYLEKVRMLEGENADLEDKIQEACSKALPILCPDYLSYYTTIEELQQKILCTKAENS
                     RLVSQIDNTKLAADDLRANYEAELSLRQLVEADANGLKQILDALTLSKADLEARVQSL
                     TEELLCLKTNHEEEVNSLQCQLGDRINIEVTAAPSVDLNQILQEMRCRYESIMETNRK
                     DVEEWFNTQMEELNQQVVSSSQQQQCCQKDIIELRRTISALEIELQAQHRMRESQECI
                     LTETEARYTALLAQIQSLIHNLEAQVADIRSALQRQSQEYEVLLDIKSRLECEIATYR
                     SLLESLDGRLPCNPCATKWEPSCQARAMECFTPVYTSSSLPGIHKPCRASGPPSRILV
                     KICTITKEIKDGKVISSYEHVQPCYITRATKV"
     exon            534..616
                     /gene="Krt39"
                     /gene_synonym="4732494G06Rik; Ka35"
                     /inference="alignment:Splign:2.1.0"
     exon            617..773
                     /gene="Krt39"
                     /gene_synonym="4732494G06Rik; Ka35"
                     /inference="alignment:Splign:2.1.0"
     exon            774..935
                     /gene="Krt39"
                     /gene_synonym="4732494G06Rik; Ka35"
                     /inference="alignment:Splign:2.1.0"
     exon            936..1061
                     /gene="Krt39"
                     /gene_synonym="4732494G06Rik; Ka35"
                     /inference="alignment:Splign:2.1.0"
     exon            1062..1282
                     /gene="Krt39"
                     /gene_synonym="4732494G06Rik; Ka35"
                     /inference="alignment:Splign:2.1.0"
     exon            1283..3193
                     /gene="Krt39"
                     /gene_synonym="4732494G06Rik; Ka35"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3171..3176
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Krt39"
                     /gene_synonym="4732494G06Rik; Ka35"
                     /note="hexamer: AATAAA"
     polyA_site      3193
                     /gene="Krt39"
                     /gene_synonym="4732494G06Rik; Ka35"
                     /note="major polyA site"
ORIGIN      
        1 aggctggcat ttgggcttgg ttgagggtgc ttcgggtggt gacctcagac tcagagacaa
       61 cgtgaagctg aacacacacc atggatacca agggctctac agtgacgatt tcttcttcaa
      121 ccccacccca aaactgctct gggaatacaa attttaggac gaactcttct tctaacaaga
      181 gctgttgtca tgatggccag tcaactggct gtgctctaca aactccccag ggccagggct
      241 gtggatccag cccttgcctt tatcgatgcc ctcattactt gataagaacc tacagcttcc
      301 atccttgtct ggatgatggc agcaggtgca ctgaaggcat taacactcat gagaaggaga
      361 ccatgcagat tttgaacgaa cgccttgcaa actatctgga aaaggtgcgg atgctggaag
      421 gagagaacgc ggacctagag gataaaatcc aggaggcatg cagcaaggcg ctccccatcc
      481 tgtgtcctga ctacctgtcc tactacacca ccatcgagga gctgcagcag aagatcttgt
      541 gtaccaaggc tgaaaattcc agactggtct cacaaattga caacaccaaa ctggctgcag
      601 atgacttgag agccaactat gaagctgagt tgtccctgcg ccagcttgtg gaagccgatg
      661 ccaatggcct gaagcagatc ctggatgcac tcactctgag caaggctgac ctggaggccc
      721 gagtccagtc tctgacggag gaacttctgt gcctcaaaac gaaccatgag gaagaagtta
      781 attccttaca gtgccaacta ggggacagaa tcaacattga agtaacagct gccccttctg
      841 ttgacctaaa tcaaatccta caagaaatga gatgccggta cgagtccatc atggagacaa
      901 accgtaaaga cgtagaagaa tggttcaata cacagatgga ggaactgaat caacaagtag
      961 tgagcagctc tcagcagcag caatgctgcc agaaggacat catagagctg agacggacca
     1021 taagtgccct cgagattgag ctgcaggccc agcacagaat gagagagtcc caggaatgca
     1081 tcctgacgga gacggaggcc cgctacacag ccctgctggc ccaaatccag agtctgatcc
     1141 acaacctgga ggctcaggtg gcagatatcc gcagtgccct gcaaagacag agccaggaat
     1201 atgaagttct gctagacatc aagtcccggc tggagtgtga gatagccaca taccgaagcc
     1261 ttcttgagag cttagatggc aggcttccct gtaacccatg tgccactaag tgggagccat
     1321 cctgccaggc cagagctatg gagtgtttta ccccagttta tacatcttca tcactccctg
     1381 ggattcacaa gccctgccgt gcctctggac ccccatcccg gatacttgtt aagatatgca
     1441 ccatcaccaa ggagatcaag gatgggaagg tcatttcttc ttacgagcat gtgcagcctt
     1501 gctacatcac cagagctacc aaagtctagc atctcaaggt gataagaatg acctccattc
     1561 atgaaagaga ggccagtgca tgctcctgcc agaaaggctt aagaaacccc cagtccctta
     1621 aggtacctag tttcttacta ctacagtggg ctcccatgtg ttcttctcct tccctaagtc
     1681 actgctacca acatgataat aagtcacatt tctctggaag gacattacgt attgtcgcag
     1741 ggatgggaac tggttagcta gtgcctacat tgcttgccta gtcaggtgtc ggacaggcag
     1801 gttttccttt tgtttattca agccttgttt atctctgtac ctctgtagag ccagtcagac
     1861 aagttctggg gttggttttg gcagttggca cgtgaaacgt aaaaagccac agccttgcct
     1921 tctgaattcc ttctttggat gtagaatgaa gccgacacag gaaccgaata aataaggaag
     1981 acccagatga ctagtcccca ggaatgaaac aatgatatgc ctggatcctg ctgaccttcg
     2041 ccacctcaac caattgattc tctgtactag tatattttcc tgttaccaaa acagaacttg
     2101 gggggggggg ctttctgcat gctctagatt cttctcccat tctgattttc atcttttatt
     2161 ttcagactgg gtcttactaa atagccaagg ctgaccttga acttactctg tatcccagct
     2221 gggacataaa cctgtggtcc cctgcctcat cctcctaagt atgtgggatc ggaggcctac
     2281 tggggccatt acataaggca gatgtccaca gtctctgaaa cttgaggaac cacaaggctc
     2341 ttctccaaat actttcttta agaatgaaga ttagttgtgt agtatgaatc caagggtctc
     2401 tctttaggat catgttgaag caatagcctg ggtccgctca ttaaaggttg gctgtttctc
     2461 ttcctatccc ttagggtatg ggagtttgat ctgcttgttt gacaatgggc atagagctgg
     2521 atttctcaag acataagacc tgatgggtaa caaggacaaa atagcttaga tgcctgcatc
     2581 aatccttcca tcagagaggg atggaattaa gagcaccaaa ctttccaaaa gagcattagt
     2641 gagtaatttc tgcttgccag taagaggctg ctgcaaatac cagcagtcac cattcagctc
     2701 cagccagtat cacaactttt agagcaggtc cacagagcag gggagtcatt cttaaaaaaa
     2761 atatattgga ccttttcaga ggtgtcagct taaaaaaaaa agtctaaatc aaacacaaac
     2821 tgtagagttc caagacctga ttcttaaact tgccaatttc ctatcatgac tctgcataaa
     2881 atgtccagcc ttcctcaaac tgatatcctt atttactcac tgagggtcac acctgcttca
     2941 aagggctgtt gtggagatca cttgaaaccc attctgtacc tggtccttgt gtatgtttag
     3001 ccattagcta attagctaga cttaattttc tttcatcatt acttcatttt aaaattcttt
     3061 ctctgcgaat ttagttatcc agtcatgatt caaaagtttt taacaatgtt cagcaatggt
     3121 gtggggggtg caaaaataga acatctgtga ttatactcat aattatacta aataaagcat
     3181 ctctgaattc tta
//
