LOCUS       NM_028660               1475 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus kallikrein related-peptidase 9 (Klk9), mRNA.
ACCESSION   NM_028660 XM_133405
VERSION     NM_028660.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1475)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1475)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1475)
  AUTHORS   Murakami,K., Tanaka,T., Bando,Y. and Yoshida,S.
  TITLE     Differences in Kallikrein-related peptidase mRNA sequences and KLK6
            enzyme activity between mouse strains
  JOURNAL   Protein Pept Lett 22 (3), 204-211 (2014)
   PUBMED   25666037
REFERENCE   4  (bases 1 to 1475)
  AUTHORS   Olsson,A.Y., Lilja,H. and Lundwall,A.
  TITLE     Taxon-specific evolution of glandular kallikrein genes and
            identification of a progenitor of prostate-specific antigen
  JOURNAL   Genomics 84 (1), 147-156 (2004)
   PUBMED   15203212
REFERENCE   5  (bases 1 to 1475)
  AUTHORS   Borgono,C.A., Michael,I.P. and Diamandis,E.P.
  TITLE     Human tissue kallikreins: physiologic roles and applications in
            cancer
  JOURNAL   Mol Cancer Res 2 (5), 257-280 (2004)
   PUBMED   15192120
  REMARK    Review article
REFERENCE   6  (bases 1 to 1475)
  AUTHORS   Olsson,A.Y. and Lundwall,A.
  TITLE     Organization and evolution of the glandular kallikrein locus in Mus
            musculus
  JOURNAL   Biochem Biophys Res Commun 299 (2), 305-311 (2002)
   PUBMED   12437987
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BX520246.1, BC109326.1, AI536290.1 and AI414707.1.
            
            On Oct 31, 2007 this sequence version replaced NM_028660.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK004807.1, BC109326.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849376, SAMN00849387
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-88                BX520246.1         1-88
            89-1039             BC109326.1         1-951
            1040-1379           AI536290.1         150-489
            1380-1475           AI414707.1         1-96                c
FEATURES             Location/Qualifiers
     source          1..1475
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 28.26 cM"
     gene            1..1475
                     /gene="Klk9"
                     /gene_synonym="1200016C12Rik"
                     /note="kallikrein related-peptidase 9"
                     /db_xref="GeneID:101533"
                     /db_xref="MGI:MGI:1921082"
     exon            1..149
                     /gene="Klk9"
                     /gene_synonym="1200016C12Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             107..862
                     /gene="Klk9"
                     /gene_synonym="1200016C12Rik"
                     /note="kallikrein-like protein 3; kallikrein 9"
                     /codon_start=1
                     /product="kallikrein-9 precursor"
                     /protein_id="NP_082936.2"
                     /db_xref="CCDS:CCDS39937.1"
                     /db_xref="GeneID:101533"
                     /db_xref="MGI:MGI:1921082"
                     /translation="MKLGLTLVLFSLLAGHCGADTRAVGARECVRNSQPWQAGLFYLT
                     RQLCGATLINDQWLLTAAHCRKPYLWVRLGEHHLWRWEGPEQLLLVTDFFPHPGFNPD
                     LSANDHNDDIMLIRLPRKVRLTPAVQPLNLTESRPPVGTQCLISGWGSVSSSKLQYPM
                     TLQCANISILDNKLCRWAYPGHISEKMLCAGLWEGGRGSCQGDSGGPLVCEGTLAGIV
                     SGGSEPCSRPRRPAVYTNVFDYLEWIESTMEKN"
     exon            150..306
                     /gene="Klk9"
                     /gene_synonym="1200016C12Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            307..572
                     /gene="Klk9"
                     /gene_synonym="1200016C12Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            573..709
                     /gene="Klk9"
                     /gene_synonym="1200016C12Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            710..1475
                     /gene="Klk9"
                     /gene_synonym="1200016C12Rik"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 attaatcaca gggcggcccc aacggaggag gaaggaagat ctctatggct taccataaag
       61 aaggccaggc gcccagtagc aggccaaagg acctgtgccc aaggacatga agctgggact
      121 caccttggtg ctgttctctc tgctggcagg ccactgtgga gctgacaccc gtgccgtcgg
      181 agcccgggaa tgcgtacgca actctcagcc ctggcaggct ggcctcttct acctcacccg
      241 gcagctctgt ggagccacgc tcatcaatga tcaatggctg ctcacagctg ctcactgccg
      301 aaagccgtac ctgtgggtcc gcctcgggga gcatcatctg tggcggtggg agggccctga
      361 gcagctgctt ctggtcacag acttcttccc ccatcctggg ttcaatccag atctctctgc
      421 caatgaccac aatgatgata ttatgctgat ccggctacct cggaaggtcc ggctgactcc
      481 agctgtgcaa cccctcaacc tcaccgagag ccggccacct gtgggcaccc agtgccttat
      541 ctctggctgg ggcagtgtgt caagctccaa attacagtat ccaatgacac tgcagtgtgc
      601 caacattagc attctggaca acaagctctg ccgctgggca tacccgggcc acatctctga
      661 gaagatgctg tgcgctggcc tgtgggaggg tggccgaggc tcttgccagg gtgactctgg
      721 gggacccctg gtgtgcgaag gaaccttggc aggtatagtg tctggaggat ctgagccttg
      781 ttccagaccc cggagacccg ctgtctacac taacgtcttt gactacctgg agtggattga
      841 aagcaccatg gaaaaaaact gagttcatgc taagatggac agactggaga ggaagacgga
      901 tgtagaatga gaggatgctg caggattcca gagccccagc ttctctgatg cgtgtcaaag
      961 cacccccgca cgccccatga tgaaactccg ccctctcaga cttcggaccc tcagacttca
     1021 ctccttagtc tcccccgaag actcctccca cttaggtcat cttccctctt ggggtctgct
     1081 cccaggcaaa acaattataa taaaaccacg ccccttcaaa aaaaaaaaaa aaaccaactg
     1141 agacacacct cctttgctcc tggcccatgc tacaccattt taatcaccat tctctggaat
     1201 agcccaaccc tcaggatcac cgccaagaaa tatctttccc taaatagctg ctgcaaccct
     1261 tcatatttca cccaatagga tttcttctct ggactccatc ccatttgtcc ccactcctag
     1321 tcacgctagg actgcgccta ttctgcgcac gtggacctca aacagctctg ggttctgctc
     1381 cgagtgtgtt ttgggtctga ctcttgacat aggatgatgg gagcattgat ctctctagag
     1441 cccccaggtg aatcagaata aaccatagga acgat
//
