LOCUS       NM_172871               4217 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus kelch-like 9 (Klhl9), mRNA.
ACCESSION   NM_172871
VERSION     NM_172871.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4217)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 4217)
  AUTHORS   Wiese,C.B., Ireland,S., Fleming,N.L., Yu,J., Valerius,M.T.,
            Georgas,K., Chiu,H.S., Brennan,J., Armstrong,J., Little,M.H.,
            McMahon,A.P. and Southard-Smith,E.M.
  TITLE     A genome-wide screen to identify transcription factors expressed in
            pelvic Ganglia of the lower urinary tract
  JOURNAL   Front Neurosci 6, 130 (2012)
   PUBMED   22988430
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 4217)
  AUTHORS   Bulfone,A., Carotenuto,P., Faedo,A., Aglio,V., Garzia,L.,
            Bello,A.M., Basile,A., Andre,A., Cocchia,M., Guardiola,O.,
            Ballabio,A., Rubenstein,J.L. and Zollo,M.
  TITLE     Telencephalic embryonic subtractive sequences: a unique collection
            of neurodevelopmental genes
  JOURNAL   J Neurosci 25 (33), 7586-7600 (2005)
   PUBMED   16107646
REFERENCE   4  (bases 1 to 4217)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Koseki,H., Hiraoka,S.,
            Saga,Y., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: III. the complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (4), 167-180 (2003)
   PUBMED   14621295
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL928605.22.
            
            On Jan 26, 2007 this sequence version replaced NM_172871.1.
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-4217              AL928605.22        79859-84075         c
FEATURES             Location/Qualifiers
     source          1..4217
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 42.02 cM"
     gene            1..4217
                     /gene="Klhl9"
                     /gene_synonym="8030469P05; C530050O22Rik; mKIAA1354"
                     /note="kelch-like 9"
                     /db_xref="GeneID:242521"
                     /db_xref="MGI:MGI:2180122"
     exon            1..4217
                     /gene="Klhl9"
                     /gene_synonym="8030469P05; C530050O22Rik; mKIAA1354"
                     /inference="alignment:Splign:2.1.0"
     CDS             507..2360
                     /gene="Klhl9"
                     /gene_synonym="8030469P05; C530050O22Rik; mKIAA1354"
                     /codon_start=1
                     /product="kelch-like protein 9"
                     /protein_id="NP_766459.2"
                     /db_xref="CCDS:CCDS38800.1"
                     /db_xref="GeneID:242521"
                     /db_xref="MGI:MGI:2180122"
                     /translation="MKVSLGNGDMGVSAHLQPCKSGTTRFFTSNTHSSVVLQGFDQLR
                     IEGLLCDVTLVPGDGEEIFPVHRAMMASASDYFKAMFTGGMKEKDLMCIKLHGVNKVG
                     LKKIIDFIYTAKLSLNMDNLQDTLEAASFLQILPVLDFCKVFLISGVSLDNCVEVGRI
                     ANTYNLIEVDKYVNNFILKNFPALLNTGEFLKLPFERLAFVLSSNSLKHCSELELFKA
                     ACRWLRLEDPRMDYAAKLMKNIRFPLMTPQDLINYVQTVDFMRTDNTCVNLLLEASNY
                     QMMPYMQPVMQSDRTAIRSDSTHLVTLGGVLRQQLVVSKELRMYDERAQEWKSLAPMD
                     APRYQHGIAVIGNFLYVVGGQSNYDTKGKTAVDTVFRFDPRYNKWMQVASLNEKRTFF
                     HLSALKGHLYAVGGRSAAGELATVECYNPRMNEWSYVAKMSEPHYGHAGTVYGGLMYI
                     SGGITHDTFQNELMCFDPDTDKWTQKAPMTTVRGLHCMCTVGDKLYVIGGNHFRGTSD
                     YDDVLSCEYYSPTLDQWTPIAAMLRGQSDVGVAVFENKIYVVGGYSWNNRCMVEIVQK
                     YDPEKDEWHKVFDLPESLGGIRACTLTVFPPEENPGSPSRESPLSAPSDHS"
     regulatory      4197..4202
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Klhl9"
                     /gene_synonym="8030469P05; C530050O22Rik; mKIAA1354"
                     /note="hexamer: AATAAA"
     polyA_site      4217
                     /gene="Klhl9"
                     /gene_synonym="8030469P05; C530050O22Rik; mKIAA1354"
                     /note="major polyA site"
ORIGIN      
        1 agctgtgcag ccgctcctag cccgggggat cctgggattc tgcctttccg gaaggtcggg
       61 ctggctctcg gtgctaggcc gccgttctag gcccaagtcg ggattccagg ccctgctcca
      121 agccaagtcc gtagccgcga cgacacagcg gggatcgcag aggacgcggc cgcagctcgt
      181 tggggtggct gagccttgga gggcggcagc cggggtgcgc aggccgtgac ggcccctccc
      241 ccgccctgag cgcagcggcg aaggacgaca gcccgggacc ggaggaggtg aagcggtcac
      301 gtaactgccc cgggtgatga ctcacccgct ctcctggcag atttgaggtg cgtgctgctg
      361 ttgctgcagg gcggacgtcg gtgtgcccag agcggtgctg cggcgaccgc ttgcttgccc
      421 ttggttcggc ggccccgggg tttcccgaga gcgttctctt tgtaacgtct gcggcctgca
      481 gctcgcagcg agctccggct tctcccatga aggtgtctct gggtaacggc gacatgggcg
      541 tctctgccca cctgcagcct tgcaagtctg gaactacgcg gttttttacc agcaacacgc
      601 acagttcggt tgtattgcaa ggctttgatc agctcagaat agagggccta ctttgtgacg
      661 tgacgctggt acctggcgat ggagaggaaa tcttcccggt tcatagagcc atgatggcgt
      721 ctgccagtga ttatttcaag gccatgttca ctggaggaat gaaagagaaa gatttgatgt
      781 gcatcaagct tcatggggtg aacaaagttg gtctgaagaa aatcattgat tttatttata
      841 ctgcaaaact gtctcttaat atggacaatc ttcaggacac tcttgaagct gccagctttc
      901 tacagatctt gccggttttg gatttttgta aagtatttct tatatcaggc gtctctttgg
      961 ataactgtgt ggaggttggc cggattgcta acacctacaa tcttatagaa gtggataaat
     1021 acgtaaataa tttcatcctg aagaactttc ctgccttgtt gaatactggg gagtttctga
     1081 aactcccctt tgaacggctt gcctttgtgc tttccagcaa tagtctcaag cactgttcgg
     1141 aacttgagct cttcaaggca gcctgccgct ggctgaggct ggaagaccct cggatggact
     1201 atgccgcaaa attaatgaag aatattcgct ttccactgat gacaccacag gatctcatca
     1261 actatgtgca gacagtagat ttcatgagaa cagacaatac ctgtgtgaat ttacttttgg
     1321 aagcaagcaa ttaccaaatg atgccgtata tgcagccggt gatgcagtcg gacagaactg
     1381 ccattcgatc tgattctact catttggtta ccttaggagg agttttgaga caacagctag
     1441 ttgtcagtaa agagttacga atgtacgacg aaagggcgca ggagtggaag tcgttagcgc
     1501 ccatggatgc tcctcgatac cagcatggca ttgctgttat tggaaatttc ctttatgtag
     1561 ttggtggcca gagtaattat gatacaaaag gaaaaacggc tgttgataca gttttcagat
     1621 ttgatcctcg ttataataag tggatgcagg tggcatcatt aaacgaaaag cgcacattct
     1681 ttcacctgag tgccctcaaa ggacatttat atgcagttgg tgggcgcagt gcagctggtg
     1741 aactggccac agtagaatgt tacaacccaa gaatgaatga atggagctac gttgcaaaga
     1801 tgagtgaacc ccactatggc catgctggaa cagtatatgg gggtttaatg tatatttccg
     1861 gaggaatcac tcatgacact ttccaaaatg agctcatgtg ttttgaccca gatacagaca
     1921 aatggacaca gaaggctcct atgactacag tccgaggtct gcattgcatg tgtacagttg
     1981 gagacaagct gtatgtcatc ggtggcaacc acttcagagg aacaagtgat tatgatgatg
     2041 tcctaagctg cgaatactat tcgccaactc ttgaccagtg gacaccaatt gctgctatgc
     2101 tgagaggtca gagtgatgtt ggagttgcag tctttgaaaa caaaatctat gttgttggtg
     2161 gatattcttg gaataaccgg tgcatggtag aaattgtcca gaaatatgac ccagaaaaag
     2221 acgagtggca taaagttttt gatcttcctg agtcgctggg tggcattcgg gcttgcactc
     2281 tcacagtttt tccacctgaa gaaaaccctg ggtcaccttc tagagaatca cctctttcag
     2341 caccttcaga tcattcttag atccaaggtg taataccttt tcagtgtatc atgggtggtc
     2401 ttgttcatcc ccttgtattg tttctcctta ttgctacagt taatagacaa aaaggtaact
     2461 tagacccttt tttttttttg gtttggcttg atattgttta gtaaatggct atacaagtgc
     2521 attttgaaaa gtattaaata tattcagctg ttttaacaag taaaaaagat acatagaaaa
     2581 ttagattttt ttttgtggtg ttacatgtgt caaattatag atgatcttag taaatgtgta
     2641 attatgtctg ttatactaaa aattaaaaca tttgatttga ctgaaacatt aaatggaggt
     2701 cccctgttct aacctaatat aaagattgcc aaggtacagc tacctccctc ttggatagtt
     2761 ttggacaatc tgttgtctag gctgtgtgat tagtcttaga atatttgaag tttcctaggt
     2821 agacagaaat agtaacaata ttaactagaa gaaacaggtc aggatttgtt ctctcactgg
     2881 agaaaaaata ataggtgtgt acactagtca gatattcatg ctcactcaaa aatttgtgta
     2941 cacacataaa cttttagact tgatagaaac ttcaactgtt gtgaaaatga ccttatattt
     3001 tcttccagaa agcagctaat tttatttcaa tgagaattca ataccagaga gtccgtgtct
     3061 aaagtcttaa accgaattta gatagctaag ggctacaaca aactaaattg acagccaaat
     3121 ttgtcattta atagaatttt ttctttaaat gaaatttaat tagtttttct gtagtctgta
     3181 gttacatgct tatttagcag aaagcaagtt tcaaagaact gtttttgtct ttgttgtttt
     3241 ttttatcatt aacttttacc tgtgaaaatc gggagttaag gaaggcatag aagcattctc
     3301 aacaaagctc caggatttta agtttagtct cctgcctcag tcactctgac atgcctatta
     3361 tgtgattttg aatgattttt tttttctttt tttttttttt tttggtgctg aggtagctgg
     3421 taagcatcct gtaatgtgtg agctgcctca aggctgtgat ctgagcaaac agatacaccc
     3481 tgttctgcat caaatcagaa ttacgccttt ttagccttga ctcaaaaata gaaccagctc
     3541 agatccccta agaagtcagc tggtttcttt aaggcagtgc taaagtagac cttcagtctt
     3601 caatactgtg ggaatacttt ctgcctgaga attacatggg aaaatcttaa agggaactta
     3661 tcagataaat ggaattatag tgtcccttgg taatgagtga tactgaatat gtactttcct
     3721 gggaaaattg ttcaactgaa ggaaaaaaat acacacacac acctagtcct gggagagtgc
     3781 cagagtgctg ttgacagtcc cttaatgtaa ttcagacaaa gtgaaaggat tcggcttctg
     3841 gcttctgaac tttaacttaa ctgcccataa gtgttgactc attttaatgc ttttcatgat
     3901 ttctgcattg acagaatttt catactttgt gtgtgtggtt ttttttaaaa tgactttttt
     3961 tgttaacttc agacatattt gattactttt agaaggtaga aattgctact aactttgtgt
     4021 attgaataag taagaaattg catcctgatt ttttcctttt attaatagca agattgaata
     4081 cttgtgtatt ttgaatagct acattttccc tttggtcaaa tgtcagtgtc cttttccttg
     4141 tgatatcttt tggagttgct ttgtttttca tatcaagtta gaggatctct ttatataata
     4201 aaattactta actgata
//
