LOCUS       NP_808423                581 aa            linear   ROD 28-APR-2025
DEFINITION  kelch-like protein 38 [Mus musculus].
ACCESSION   NP_808423
VERSION     NP_808423.1
DBSOURCE    REFSEQ: accession NM_177755.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (residues 1 to 581)
  AUTHORS   Luo,Y., Tian,L., Liang,C. and Xu,Y.
  TITLE     KLHL38 facilitates staurosporine-induced apoptosis in HL-1 cells
            via myocardin degradation
  JOURNAL   IUBMB Life 74 (5), 446-462 (2022)
   PUBMED   35112472
  REMARK    GeneRIF: KLHL38 facilitates staurosporine-induced apoptosis in HL-1
            cells via myocardin degradation.
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AK033353.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK033353.1, BC132483.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..581
                     /organism="Mus musculus"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="15"
                     /map="15 24.62 cM"
     Protein         1..581
                     /product="kelch-like protein 38"
                     /calculated_mol_wt=65520
     Region          11..139
                     /region_name="BTB_POZ"
                     /note="BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ
                     (poxvirus and zinc finger) domain superfamily; cl38908"
                     /db_xref="CDD:453885"
     Region          131..229
                     /region_name="BACK_KLHL38"
                     /note="BACK (BTB and C-terminal Kelch) domain found in
                     Kelch-like protein 38 (KLHL38); cd18476"
                     /db_xref="CDD:350551"
     Region          281..321
                     /region_name="Kelch_6"
                     /note="Kelch motif; pfam13964"
                     /db_xref="CDD:404790"
     Region          285..332
                     /region_name="Kelch 1"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8BSF5.1)"
     Region          310..571
                     /region_name="NanM"
                     /note="N-acetylneuraminic acid mutarotase [Cell
                     wall/membrane/envelope biogenesis]; COG3055"
                     /db_xref="CDD:442289"
     Region          325..369
                     /region_name="KELCH repeat"
                     /note="KELCH repeat [structural motif]"
                     /db_xref="CDD:276965"
     Region          334..383
                     /region_name="Kelch 2"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8BSF5.1)"
     Region          373..417
                     /region_name="KELCH repeat"
                     /note="KELCH repeat [structural motif]"
                     /db_xref="CDD:276965"
     Region          384..431
                     /region_name="Kelch 3"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8BSF5.1)"
     Region          421..508
                     /region_name="KELCH repeat"
                     /note="KELCH repeat [structural motif]"
                     /db_xref="CDD:276965"
     Region          433..479
                     /region_name="Kelch 4"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8BSF5.1)"
     Region          480..521
                     /region_name="Kelch 5"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8BSF5.1)"
     Region          511..561
                     /region_name="KELCH repeat"
                     /note="KELCH repeat [structural motif]"
                     /db_xref="CDD:276965"
     Region          523..573
                     /region_name="Kelch 6"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8BSF5.1)"
     CDS             1..581
                     /gene="Klhl38"
                     /gene_synonym="8230402K04Rik"
                     /coded_by="NM_177755.3:213..1958"
                     /db_xref="CCDS:CCDS27492.1"
                     /db_xref="GeneID:268807"
                     /db_xref="MGI:MGI:3045310"
ORIGIN      
        1 mdeelpdgvv fkdhsfssdl lrqlnglrqs kiltdvsics gawevpchrs vlassspyfk
       61 amfcshfres reakvqmkgi ssttleqvit yvytgevhis aanvlplmea aamlqyprvf
      121 eacssylqsq lapsnclglv rlaeilscds lkkkakeval tyfpevaasa dlkelcamel
      181 rdylgddrlc geeekvfeal mawvkhdlqa rwrhmqellq qvrlqyihpa ffhhfianda
      241 llqsspacqa ilemarkqif slygpsaqdc kllwrmpprs syqdfllllg grkdnqqttr
      301 dvllysgqtg qwqslaklpi rlykasavtl hrsvyvlggm tvsegkslis cgvyifslkl
      361 nqwrvgepml aaryshrstt hrnfifsigg tgegqellas merydsirdv wesmagmpva
      421 vlhpavavkd qrlylfgged imqnpvrliq vyhisrntwy kmetrmiknv capavvlgeq
      481 ivivggytrr ilaydpqsnk fvkcadmkdr rmhhgatvmg nklyvtggrr lttdcnieds
      541 asfdcydpet dtwtsqgqlp hklfdhaclt lqciphmtsl s
//
