LOCUS       NM_001081667            2740 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus kelch-like 34 (Klhl34), mRNA.
ACCESSION   NM_001081667 XM_142269 XM_911737 XM_984451
VERSION     NM_001081667.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2740)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL732396.11.
            
            On Feb 2, 2022 this sequence version replaced NM_001081667.2.
            
            ##Evidence-Data-START##
            Transcript is intronless :: SRR1660819.193514.1,
                                        SRR1660815.114762.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2740              AL732396.11        43328-46067
FEATURES             Location/Qualifiers
     source          1..2740
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="X"
                     /map="X 72.76 cM"
     gene            1..2740
                     /gene="Klhl34"
                     /gene_synonym="Gm388"
                     /note="kelch-like 34"
                     /db_xref="GeneID:245683"
                     /db_xref="MGI:MGI:2685234"
     exon            1..2740
                     /gene="Klhl34"
                     /gene_synonym="Gm388"
                     /inference="alignment:Splign:2.1.0"
     CDS             513..2447
                     /gene="Klhl34"
                     /gene_synonym="Gm388"
                     /codon_start=1
                     /product="kelch-like protein 34"
                     /protein_id="NP_001075136.1"
                     /db_xref="CCDS:CCDS41191.1"
                     /db_xref="GeneID:245683"
                     /db_xref="MGI:MGI:2685234"
                     /translation="MSYFLSYCKTHGSSLLTGYQALRAEGFLCDVTLEAEGSEFPAHR
                     SLLACSSDYFRALFKSHTQESRARVIHLRVPSAAGLQRLLDFIYTAWLPLSMDTVEDT
                     LEAASYLQVTEALGLCAHYLERQLAPENCCFIANVAARFGLARTLGAAECCIVRHLGG
                     LLLMGTGPSGLLELNPISMKAVLGAPDVARVPETRLLGLALAWLQQEPKVQRLAHSST
                     LLGCIRFGLVPAGVLRRIYSGSGLILPTRIKSLIIQALNYHTAPSSQPLLQGEQTSVR
                     SPQTRILLVGGLRAREMVTEEIMGLPEVVQNRHPAPQPEEEEGQEEEEMEEKEWELTQ
                     DVVSFDVYNHSWHSLTQLPTPLLGHSVCTTGNFLFVLGGESLPGSPSSSLAAGSRSIT
                     ALVHRYDPRFHTWTQVPAMREARAYFWCGVVGESLLAVGGLGICGEALASVEMYDLRR
                     DRWMAAGQLPRAVHGHAGAVGDHGVVYISGGKAGRGEGGTSSLRDMYSLSPGERVWSK
                     RAPMGTARYGHYLVVLRGAVFAFLGRYEPFSEIERYDPCTDQWTRLRSLPYDRFCYGL
                     AVVEETVLLLGGLKWRDSRQVPTRNVVGYDLDLDRWEDIGCVLPWAWSGLQCAVLQLP
                     EGREETREGETGEVPDLVLD"
     regulatory      2714..2719
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Klhl34"
                     /gene_synonym="Gm388"
                     /note="hexamer: AATAAA"
     polyA_site      2740
                     /gene="Klhl34"
                     /gene_synonym="Gm388"
                     /note="major polyA site"
ORIGIN      
        1 agttgtcctc ggactgtgcg agtgtctacg gagcagccac gatcagagcc accatcctgc
       61 tgtcctgggg cacccacaat agggccacat ccacgcatct ggccttctgg agattcagta
      121 ccctcgacct ctccaggtga tggtgcgcgg ccaccgccgc ccctggtgtg caagtgtggg
      181 ttccccaaat tgtgtagggg aggcggcttt gggcaacgcg ctgtcatgct caccagctga
      241 aaacaagtct agcaataccg agaagactcc gaaatccaca ccctctgcta ctagaggctt
      301 ttggaaattg tctctacatc ttactttgtc tgagaggggc acggagcaac agccaaatct
      361 ggatgaagga accttaggtt ttaagctgag caggcaaaaa tcagcctttg ctaggggctc
      421 agcagctgga cagcggaggt gggggttccg tgttatggga tgcctccagc cgcgctgggc
      481 tggctccatc ccagcttccc gccttgggca tcatgagtta cttcctgtct tactgcaaaa
      541 cccacggcag ctctcttctc actggctacc aggccctacg cgctgagggc ttcttgtgcg
      601 acgtgacact ggaggccgag ggcagtgagt tcccagcaca caggtcactt ctggcgtgct
      661 ccagcgacta cttcagggcc ctgttcaaga gtcacactca ggaatcgcgg gctcgcgtaa
      721 ttcacctgcg tgtgccttca gcggccggcc tacagcgcct gctggacttc atctacactg
      781 cctggctgcc cctctccatg gacactgtgg aggacactct ggaggctgcc agctacctgc
      841 aagtcaccga ggccttggga ctgtgtgccc actacttgga acgccagctt gccccagaga
      901 attgctgttt cattgccaat gtggcagctc gatttggcct ggcccgcacc ctaggtgcag
      961 cggagtgctg tattgtacgc cacctggggg gcctgttact gatgggcact ggcccctcgg
     1021 ggctgttgga actcaatcct atatcaatga aagctgtgct gggcgcccct gacgtggcac
     1081 gggtgcctga gacgcggctg ctgggcctgg cactagcctg gctgcagcag gaacccaagg
     1141 tccagcgcct ggcacatagt tcaacactgc ttggatgcat ccgctttggc ctggtgcctg
     1201 ctggtgtgct gcggcgcata tactcgggct ccggtcttat attacctact aggatcaaaa
     1261 gcctcatcat ccaggccctc aattaccata cagcaccctc cagccagccg cttctgcagg
     1321 gagaacagac tagtgttcgg agtccccaga cccgtatctt gctagttggt ggtctcagag
     1381 ctagggagat ggttaccgag gagatcatgg gcctaccaga ggtagttcag aatcggcacc
     1441 ctgcacctca accagaggaa gaggagggac aggaggagga agagatggag gagaaggagt
     1501 gggagctcac ccaggatgtg gtgtccttcg acgtgtataa ccacagctgg cacagcttga
     1561 cacagctgcc cacaccactg ctaggccaca gtgtatgtac cactggcaac ttcctatttg
     1621 tccttggagg ggagagcctt cctggcagcc catctagttc cctggctgcc ggctcaaggt
     1681 caatcacagc cttagtgcac cgttatgacc cgcgcttcca cacttggaca caggtgcctg
     1741 ccatgcgaga agcaagggcc tacttctggt gtggtgtggt aggtgagagt ctcctggctg
     1801 tcggaggcct gggcatctgt ggtgaggcac tggcctcagt ggagatgtat gaccttcgca
     1861 gggaccgctg gatggcagct ggacagctac ctcgggcagt acatggtcac gcaggtgctg
     1921 tcggggatca tggtgttgtg tacatctccg ggggcaaggc tgggagaggt gaaggaggca
     1981 caagtagcct ccgggatatg tactccctta gccccggaga gagagtgtgg agcaagaggg
     2041 cacccatggg cacagctcgc tatgggcact accttgtggt gctgcgaggt gcagtgtttg
     2101 cctttttggg gagatatgag cccttctctg agattgaacg ctatgacccc tgcacagacc
     2161 agtggactcg gttgcggtcg ctaccctatg accgcttctg ctatggactt gctgtggtgg
     2221 aagagacagt gctgctgctg ggtggtctca agtggcggga ctcacgccag gtgccaaccc
     2281 ggaacgtagt gggctatgac ctggacctgg accgttggga agatataggc tgtgtgctgc
     2341 cctgggcatg gagtggcctt cagtgtgcag tgctgcagct acccgagggt agggaggaga
     2401 caagggaggg agagactgga gaggtgccag atttagtgtt ggattgaata ggtgagtcca
     2461 ggcttcagag gatccaaggg aaagttgttc ttgaccttgc ctgaagagca ctgctttgtt
     2521 cccttaagag gacttttata gagtagttct gaatggtaag gaggtgaaca aggccttggc
     2581 caaagaataa ctattcccct tcaactgcaa atgtcagtca ggaatggtca aatgcaaaga
     2641 tatgagccag ctttagttaa ctgaagaggt ttcagaaaga cagactcatt ctggcctaga
     2701 ggtggaattt gaaaataaaa taggacctta tttctctcca
//
