LOCUS       NM_172925               6260 bp    mRNA    linear   ROD 27-JUL-2024
DEFINITION  Mus musculus kelch-like 31 (Klhl31), mRNA.
ACCESSION   NM_172925
VERSION     NM_172925.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6260)
  AUTHORS   Papizan,J.B., Garry,G.A., Brezprozvannaya,S., McAnally,J.R.,
            Bassel-Duby,R., Liu,N. and Olson,E.N.
  TITLE     Deficiency in Kelch protein Klhl31 causes congenital myopathy in
            mice
  JOURNAL   J Clin Invest 127 (10), 3730-3740 (2017)
   PUBMED   28872460
  REMARK    GeneRIF: These findings highlight a role for Klhl31 in the
            maintenance of skeletal muscle structure and provide insight into
            the mechanisms underlying congenital myopathies.
REFERENCE   2  (bases 1 to 6260)
  AUTHORS   Yu,W., Li,Y., Zhou,X., Deng,Y., Wang,Z., Yuan,W., Li,D., Zhu,C.,
            Zhao,X., Mo,X., Huang,W., Luo,N., Yan,Y., Ocorr,K., Bodmer,R.,
            Wang,Y. and Wu,X.
  TITLE     A novel human BTB-kelch protein KLHL31, strongly expressed in
            muscle and heart, inhibits transcriptional activities of TRE and
            SRE
  JOURNAL   Mol Cells 26 (5), 443-453 (2008)
   PUBMED   18719355
REFERENCE   3  (bases 1 to 6260)
  AUTHORS   Wu,Y.L. and Gong,Z.
  TITLE     A novel zebrafish kelchlike gene klhl and its human ortholog KLHL
            display conserved expression patterns in skeletal and cardiac
            muscles
  JOURNAL   Gene 338 (1), 75-83 (2004)
   PUBMED   15302408
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK053085.1 and CT030709.6.
            
            On Feb 6, 2007 this sequence version replaced NM_172925.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK053085.1, SRR10223971.9503.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1819              AK053085.1         2-1820
            1820-6260           CT030709.6         69567-74007         c
FEATURES             Location/Qualifiers
     source          1..6260
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 43.36 cM"
     gene            1..6260
                     /gene="Klhl31"
                     /gene_synonym="9830147P19Rik; D930047P17Rik; Kbtbd1"
                     /note="kelch-like 31"
                     /db_xref="GeneID:244923"
                     /db_xref="MGI:MGI:3045305"
     exon            1..56
                     /gene="Klhl31"
                     /gene_synonym="9830147P19Rik; D930047P17Rik; Kbtbd1"
                     /inference="alignment:Splign:2.1.0"
     exon            57..1261
                     /gene="Klhl31"
                     /gene_synonym="9830147P19Rik; D930047P17Rik; Kbtbd1"
                     /inference="alignment:Splign:2.1.0"
     exon            1262..6260
                     /gene="Klhl31"
                     /gene_synonym="9830147P19Rik; D930047P17Rik; Kbtbd1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 accgggagag agaagctggg accgcaacta ccaactcgtg ccgactggat cctaggtgag
       61 ccgttgactg tgacagcgct gtggctaaca tggcacccaa aaagaagact atcaagaaga
      121 acaaggcaga gatcaacgag atgaccatca ttgtagaaga cagcccccta agcaagctga
      181 atgctctaaa tgggcttctg gagggaagca acagccttag ctgtgtttct tccgaactaa
      241 cagacacttc ttatggcccc aacctcctcg aaggtttaag taaaatgaga caagagagct
      301 ttctatgtga cttggtcatc ggtaccaaaa ccaagtcctt tgatgtccat aagtcagtga
      361 tggcttcatg cagcgagtac ttttataaca tccttaaaaa cgatccgtcc acgaaaaggg
      421 tagacctcaa tgatatcgcc cctttagggc tagccacagt gatcgcgtat gcttacacgg
      481 gaaagctgac cctttcttta tacacaatag gaagcatcat ttctgctgct gtgtacctcc
      541 agatccacac ccttgtaaag atgtgcagcg attttctgat ccgagagatc agtgtggaga
      601 actgcatgta cgtggttaac attgctgaga cctacagctt gaaaaacgca aaggcaacag
      661 cccagaaatt catccgggat aacttcatcg aatttgcaga atccgaacaa tttatgaagc
      721 ttacgtttga acagattaac gagcttctcg tagatgacga cttacaattg ccttctgagc
      781 ttgtagcatt ccagatcgca atgaaatggt tagaattcga ccaaaagaga gtgaagcatg
      841 cggcagatct tctaagcaac attcgctttg gtaccatctc tgcacaagac ctggtcaatt
      901 atgttcaaac cgtaccgagg atgatgcaag acgctgattg tcataaactg cttgtggatg
      961 ccatgaacta tcacttactc ccttatcatc aaaacacact gcaatctagg cgcacaagaa
     1021 ttagaggcgg ctgccgagtt ctgatcactg ttgggggacg ccccggcctg actgagaagt
     1081 cccttagtag agacatttta tatagagacc ctgaaaatgg atggagcaag cttacagaaa
     1141 tgccagccaa gagttttaat cagtgtgtgg ctgtgatgga tggattcctt tatgtagcag
     1201 gtggtgagga ccagaatgac gccagaaacc aagccaagca cgcagtcagc aatttctgca
     1261 ggtacgatcc ccgcttcaac acctggattc acttgggcag catgaaccag aagcgcacgc
     1321 acttcagcct gagcgtgttc aacgggctgc tgtacgcggt gggcggccgt aactccgagg
     1381 gcagcctggc ttcgctggag tgctacgtgc cctccaccaa ccaatggcag cccaaagcgc
     1441 cgctcgaggt ggcgcgctgc tgccacgcca gcgccgtggc cgacggccgc gtgatcgtga
     1501 ccggcggcta catcggcagt gcgtactcgc gctccgtgtg cgcctacgac cccgcgctcg
     1561 acgcgtggca ggagctgccc cagctgagca cgccccgagg ctggcactgc gcggtggcgc
     1621 tgggcgacag gctgtacgtg atggggggca gccagctggg gccgcgcggg gagcgcgtgg
     1681 acgtgctcac ggtggagagc ttcagtcccg cagcgcgcca gtggagcttc gtggcgccgc
     1741 tgcccgtggg cgtgagcacg gcgggtgtct cggcgctgca cgggcgagcc tacctgctgg
     1801 gcggctggaa cgagggcgag aagaagtaca agaaatgcat ccagtgcttc aaccccgagc
     1861 tcaacgagtg gacggaggac gacgagctgc ccgaggccac cgtgggcgtg tcctgctgca
     1921 cgctggccat gcccaacagc gtgtcccgag agtcacgggc cagctcggtg tcctccgtgc
     1981 cggtcagtat ctgaacgcat tgcttcccaa tgtggtcaaa ctgtgagtgg gccaccagga
     2041 aaatatacac catttactac agtgacggtg gttcaaatcg atccagagga gtgcctggac
     2101 cgctttaaat tcttagttta gcaccatcta cctcagtctt tccctccaaa aaaaaaaaaa
     2161 taataaaggg ctgtagccaa caaaagaagc aatttcatta tgcagccact gggtggccac
     2221 tagagtttgt tacaggcact cttgcaagga ggctcgcttc ctaaattcat agcagttaca
     2281 cacacgctga gattttccca cggtgtacac gtgaaaccta ctcgtctata caatttccta
     2341 tccaaaggag tattttcctc tctgtttctt tgaaggaagt tgaaaatacc cacttcacat
     2401 ttgcaaatga aaatagtcta catctataaa gatttaattc tatatttcaa cagaaaatta
     2461 ttctttgtcc ctacttgact ggaaagaact tttaaaaaga tctcatgaca tagccacaaa
     2521 gcttttaaca ggatgtggct ggaaagctat acattctacc taggaaacga caaggtggca
     2581 gtttggggtt aacggtgtat accccctcat tctgtccttg aagcttctgc cattttctaa
     2641 cataaaatcc tactctcaga aaaggaacag tttcctgtca tttaatttat agtgtaaatt
     2701 caaatcattt ggcatttttc ttagaaatat ttccacttgt atctctaatc cttatatgga
     2761 cagagttgtt ttttttttct tttttttttt tttttttttt tttccttttt tctggatggg
     2821 cctggtacac actagtactc tacccgggag ctaactacat atccagtctt cgctttattt
     2881 taatatttga gacatggttt cattaagtag accaggctag cctcaaactc ccagtgcctc
     2941 ctgagtgatg ggattaaagg tgtgtgccac cactcacagc cctctttctt attttaaagt
     3001 aggattttac taggttgcca ggctgctcct cctgcttcag catccccagt aggctggaat
     3061 tacaggcgtg taccatcggg tacagcttta tcttactcag gtatggtcaa attgcctcta
     3121 acattagccc gaataatcac caaatcacac tatgttcttg gatgaatatc attaactgca
     3181 gcttagcctt tggctgtaca gccaatagca gtaattttac tgacccctcg ttcacgtgga
     3241 gatgatgaag gaaatatttg gggttctcgg acttggcaat taccagatga atagatgggt
     3301 tcctcactga ggagtgctga tagctaactt aaaatattaa cccccaaaat aatgctcttt
     3361 atgatttact tttgttaata ccactttgca aatcaaactg tatctatttg gttggttggt
     3421 tggatctttt cttttctttt ctcttctttt cttttctttc cttttctttt cttttctttt
     3481 ctcttctttc tttttctttt ttcctttttc ttttcttttc tttttttttt tagacagggt
     3541 ctcactatgt agctctggct gccctagaac tcatttaggt agaccaagct ggtctcagac
     3601 tcagtaagat ctgtctctgc ctcccgagtg ctgaaattaa aggcttatgt catcctgcct
     3661 tgcaacgtgt attttcctgc taccatttcc ttgagttatc tgccaagttt ggaagaaagg
     3721 ggaagaactg tagtaaatga tggatatttt cctttaatat atcagtttat cttcatagta
     3781 tatttgtttg gggaaggaaa tgcctatcat ccatgccttc tgtacaacta gagaatttgg
     3841 agggatggag aggcatctgg aactgtatct tggttattac caatcccagc ctttcctatt
     3901 acatgtgtgt tgtagctgtc atggtcatgt ctaaagccca gtccccttgt ctgtgggtta
     3961 acacatctgt aggtgcagct agacccaaga tgaagatatt tgaaaaaaaa attgcatagc
     4021 aaacatgtac caaatatttt ctcccccccc ccagcaatac agcacaacag tttgcatagc
     4081 aattgcattg tattagatat tataataccc tagaaacaat ataacttata gaagaagatg
     4141 tgagcagggt gtatgtaaat agtacatgcc actttgtaga tgggacgtga gtgtcacaga
     4201 cactgtatcc cagcagggga tggggcatgt cctggttcca gtctcccaag gacactgagg
     4261 gatggctaca tcttattcca actgtgaaaa gtggttcaaa taaaacattc ttgagataac
     4321 cttcctcatc accccttaca aaaagttctg tttggggtat tcaacagtga tgctcaggaa
     4381 cagaggaaca gactataaac actgtaaata agtaagacac cattagcaca aagatacaga
     4441 gagaaagagg agttccatca attgcaggga aaacctaaag acacctgctc ttttgcctcc
     4501 atgactgtgc aggctggaaa acaaaactct gagcaaatat tttggggatc atttggccac
     4561 gacttgctag ggcagccatc acatcttatc agggcagtat agacacacct ctgcaattta
     4621 tgcctacagt atatgggtaa ttttgagaga gaaaagggtg cttcattggg ggctacaaat
     4681 aattgaatag actgatgtaa ttcatttatg tgcactaata gctgtgcctc aatagagaat
     4741 gtagaggtgt gtgaaaagaa ggacctaggg ctgtgaatga aataaaagtc aactcgttgt
     4801 aacattttag gatttaaaac atgcggagag agacagaaaa tagagggacc tcagttggag
     4861 ctggtaaggt aggatgtaaa gcccacgagg ttgctttcca gaggcaaagc acagcccgat
     4921 tacagcccct gggtaaattg caatcactta tgttctgtgt tgttaatctg aagactcaga
     4981 aaatatacac agctgggctt accacgtctt ggtgcactga ggttgatagg atatggtcca
     5041 tgaaagctag tgaatttttg agccccagaa tagcctgcac tgccattaag gacaaaaatg
     5101 caagaagatg caatacgttc tgtacccttc aaagtcttta atccatttcc aagttgctgc
     5161 tcctgggaag cagagtccgc tttgcaactg caaactttac atgcttgtac tgtggttcct
     5221 gcttacccct attcagttac agccacaagg taggacccaa acatgtactt gtgtttattt
     5281 ttctcaaaga aaatgtcttg tgatttttgt taatgcctga gttccgtgat taaataaatg
     5341 taccagctca gcttatcaga aaataccatg ttacccagca gccaaaacaa taaaactcaa
     5401 gctgcctttt tctgaatgga ccagagaccc gataagagcg tctccaggaa gccagatctt
     5461 aatagagtat gtccatcttc tctgggctcc caggccaacc tgtgaactct taacttacca
     5521 gttaatttca gtaggctgag ttcatttcat tttcacttcc tgttgtaagg atgggtcaca
     5581 aatagaaggt aggtggctgg tgcttcaaca tagttctcta gactgatggt gggaatgtga
     5641 ggaagcgtta tagctgaggt gataaggaag tgagtcctga aaggttctat gctttaagac
     5701 agggtgataa tgatactgtg tgtgttttac aacagtgtgt aaatagaagt tatgtggcaa
     5761 caggaggtag gtttcccacc cccactccca ctatcttgcc caaatgtctt cggaattcca
     5821 ctaaattatc aagttaaatg gacttaagac aattggttgc atttgttttc ccttagttac
     5881 aacagactcc acctctgtag ttgctgagag ctgggcccct accccagcgt aggcacaagg
     5941 cagcaagaaa aggcattctt ttcatagcaa tacaaattat actcaatact ttccattcta
     6001 aattactaga actaaaggat taaaatatta acaatttacc cccataatgt gccatttagc
     6061 attccctcga acagagtttg acacaaaatg tttatcttgg acactcctaa aatatgtttg
     6121 ttgtggttgt ttatccagca aattttggca gaaatctctt tggcttaaaa cattctggtt
     6181 tcctgtaaag aacaacaaag aaacccatac gttgtgttat tttgtaactt caccactgtt
     6241 aataaagctg catataaaaa
//
