LOCUS       NM_025707               2854 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus kelch-like 28 (Klhl28), mRNA.
ACCESSION   NM_025707
VERSION     NM_025707.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2854)
  AUTHORS   Diez-Roux,G., Banfi,S., Sultan,M., Geffers,L., Anand,S., Rozado,D.,
            Magen,A., Canidio,E., Pagani,M., Peluso,I., Lin-Marq,N., Koch,M.,
            Bilio,M., Cantiello,I., Verde,R., De Masi,C., Bianchi,S.A.,
            Cicchini,J., Perroud,E., Mehmeti,S., Dagand,E., Schrinner,S.,
            Nurnberger,A., Schmidt,K., Metz,K., Zwingmann,C., Brieske,N.,
            Springer,C., Hernandez,A.M., Herzog,S., Grabbe,F., Sieverding,C.,
            Fischer,B., Schrader,K., Brockmeyer,M., Dettmer,S., Helbig,C.,
            Alunni,V., Battaini,M.A., Mura,C., Henrichsen,C.N.,
            Garcia-Lopez,R., Echevarria,D., Puelles,E., Garcia-Calero,E.,
            Kruse,S., Uhr,M., Kauck,C., Feng,G., Milyaev,N., Ong,C.K.,
            Kumar,L., Lam,M., Semple,C.A., Gyenesei,A., Mundlos,S., Radelof,U.,
            Lehrach,H., Sarmientos,P., Reymond,A., Davidson,D.R., Dolle,P.,
            Antonarakis,S.E., Yaspo,M.L., Martinez,S., Baldock,R.A., Eichele,G.
            and Ballabio,A.
  TITLE     A high-resolution anatomical atlas of the transcriptome in the
            mouse embryo
  JOURNAL   PLoS Biol 9 (1), e1000582 (2011)
   PUBMED   21267068
  REMARK    Publication Status: Online-Only
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AC159632.2.
            
            On Apr 29, 2007 this sequence version replaced NM_025707.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK014466.1, AK012778.2 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164141
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-128               AC159632.2         149211-149338       c
            129-1027            AC159632.2         140641-141539       c
            1028-1471           AC159632.2         135178-135621       c
            1472-1680           AC159632.2         133816-134024       c
            1681-2854           AC159632.2         126242-127415       c
FEATURES             Location/Qualifiers
     source          1..2854
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="12"
                     /map="12 27.21 cM"
     gene            1..2854
                     /gene="Klhl28"
                     /gene_synonym="2810440N09Rik; 4122402F11Rik;
                     4931401E10Rik; Btbd5"
                     /note="kelch-like 28"
                     /db_xref="GeneID:66689"
                     /db_xref="MGI:MGI:1913939"
     exon            1..128
                     /gene="Klhl28"
                     /gene_synonym="2810440N09Rik; 4122402F11Rik;
                     4931401E10Rik; Btbd5"
                     /inference="alignment:Splign:2.1.0"
     CDS             129..1844
                     /gene="Klhl28"
                     /gene_synonym="2810440N09Rik; 4122402F11Rik;
                     4931401E10Rik; Btbd5"
                     /note="BTB (POZ) domain containing 5; BTB/POZ
                     domain-containing protein 5"
                     /codon_start=1
                     /product="kelch-like protein 28"
                     /protein_id="NP_079983.1"
                     /db_xref="CCDS:CCDS25938.1"
                     /db_xref="GeneID:66689"
                     /db_xref="MGI:MGI:1913939"
                     /translation="MDHTAPTYMLANLTHLHSEQLLQGLNLLRQHHELCDIILRVGDV
                     KIHAHKVVLASISPYFKAMFTGNLSEKENSEVEFQCIDEAALQAIVEYAYTGTVFISQ
                     DTVESLLPAANLLQIKLVLKECCAFLESQLDPGNCIGISRFAETYGCHDLYLAATKFI
                     CQNFESVCQTEEFFELTHADLDEIVSNDCLNVATEETVFYALESWIKYDVQERQKYLA
                     QLLNSVRLPLLSVKFLTRLYEANHLIRDDRTCKHLLNEALKYHFMPEHRLSHQTVLMT
                     RPRCAPKVLCAVGGKSGLFACLDSVEMYFPQNDSWIGLAPLNIPRYEFGICVLDQKVF
                     VIGGIETSVRPGMTVRKHENSVECWNPDTNTWTSLERMNESRSTLGVAVLAGEVFALG
                     GYDGQSYLQSVEKYIPKIRQWQPVAPMTTTRSCFAAAVLDGMLYAIGGYGPAHMNSVE
                     RYDPSKDSWEMVAPMADKRIHFGVGVMLGFIFVVGGHNGVSHLSSIERYDPHQNQWTV
                     CRPMKEPRTGVGAAVIDNYLYVVGGHSGSSYLNTVQKYDPISDTWLDSAGMIYCRCNF
                     GLTAL"
     exon            129..1027
                     /gene="Klhl28"
                     /gene_synonym="2810440N09Rik; 4122402F11Rik;
                     4931401E10Rik; Btbd5"
                     /inference="alignment:Splign:2.1.0"
     exon            1028..1471
                     /gene="Klhl28"
                     /gene_synonym="2810440N09Rik; 4122402F11Rik;
                     4931401E10Rik; Btbd5"
                     /inference="alignment:Splign:2.1.0"
     exon            1472..1680
                     /gene="Klhl28"
                     /gene_synonym="2810440N09Rik; 4122402F11Rik;
                     4931401E10Rik; Btbd5"
                     /inference="alignment:Splign:2.1.0"
     exon            1681..2854
                     /gene="Klhl28"
                     /gene_synonym="2810440N09Rik; 4122402F11Rik;
                     4931401E10Rik; Btbd5"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2061..2066
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Klhl28"
                     /gene_synonym="2810440N09Rik; 4122402F11Rik;
                     4931401E10Rik; Btbd5"
                     /note="hexamer: ATTAAA"
     polyA_site      2087
                     /gene="Klhl28"
                     /gene_synonym="2810440N09Rik; 4122402F11Rik;
                     4931401E10Rik; Btbd5"
                     /note="major polyA site"
     regulatory      2604..2609
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Klhl28"
                     /gene_synonym="2810440N09Rik; 4122402F11Rik;
                     4931401E10Rik; Btbd5"
                     /note="hexamer: AATATA"
     polyA_site      2630
                     /gene="Klhl28"
                     /gene_synonym="2810440N09Rik; 4122402F11Rik;
                     4931401E10Rik; Btbd5"
ORIGIN      
        1 ggggcggaag ttttccaccc cacccataag agttgaggtt tgacgggagc aagagaggat
       61 cccatcccgg gttccagttt tccgtggctc ctcctcctgt tgctgcaggt gttattcctg
      121 ggactcagat ggaccacaca gccccgacct acatgcttgc taacttaacc cacttacatt
      181 ctgaacaact tctgcaggga ttgaatcttc ttcgccagca tcacgaactc tgtgacatca
      241 ttcttcgagt aggtgatgtt aaaattcatg ctcataaagt ggtccttgcc agcatcagcc
      301 catacttcaa agctatgttc actggcaacc tttctgagaa agagaacagt gaggttgagt
      361 ttcagtgcat cgatgaagct gcgctgcagg ccattgtgga gtacgcctat acgggcacag
      421 ttttcatttc tcaggacaca gttgaatctc tcctgccagc agcaaactta ctccagataa
      481 aactcgttct taaagaatgc tgtgcatttc ttgaaagcca acttgaccct ggtaattgta
      541 ttggaatttc tcgttttgcg gagacttacg gttgtcatga cctttatttg gcggctacta
      601 aattcatatg ccagaatttt gaatctgttt gccagacaga agagtttttt gagcttacac
      661 atgctgattt ggacgaaatt gtctccaatg actgcttgaa tgtggctact gaagagacag
      721 ttttttatgc attagaatct tggatcaagt acgatgtaca agaacggcag aagtacttag
      781 cccagctgct gaacagtgta cggttaccat tgctgagcgt taagttcctc actaggctct
      841 atgaagcgaa tcatcttatc cgtgatgatc gcacctgtaa acatctcttg aatgaagccc
      901 taaagtacca cttcatgcct gaacatagac tctctcatca gacagtcttg atgacacgac
      961 ctcgctgtgc tcccaaagta ctgtgtgcag taggaggaaa atctggactc tttgcctgtt
     1021 tggatagtgt ggagatgtac tttccccaga atgactcttg gattggtctg gcgcccttaa
     1081 atattcctcg ctatgaattc ggaatatgtg ttttagacca aaaagtcttt gttataggtg
     1141 gtattgaaac tagcgtgcgt cctggtatga ctgtcagaaa acatgaaaat tcagtggaat
     1201 gttggaatcc tgatacaaac acctggactt ctctcgagag aatgaacgag agccggagta
     1261 ctctcggagt ggcagtgctc gcgggagaag tttttgcctt aggtggatat gacgggcagt
     1321 cttacttgca atctgtagaa aaatacatcc ccaaaataag gcagtggcaa cctgtggccc
     1381 caatgacaac cacaagaagt tgttttgctg cagctgtcct ggatggaatg ctatacgcca
     1441 ttggaggcta tggccccgct cacatgaaca gtgtggagcg ttacgatccg agtaaggact
     1501 cctgggagat ggttgcgccc atggctgata agaggattca ctttggcgtc ggagtcatgc
     1561 taggttttat tttcgtggta ggtgggcata acggtgtctc acatttgtca agcattgaaa
     1621 gatatgatcc tcatcaaaat cagtggactg tgtgtagacc aatgaaagag cccaggacag
     1681 gagttggtgc tgcagtaatc gataactacc tgtatgtagt cggtggtcac tcagggtctt
     1741 cctatctgaa cacagtacag aaatacgacc ctatctcaga tacatggctg gattcagcag
     1801 gcatgatata ctgtcgctgc aattttggat taactgcact ttgacaagtg tgaacttgtg
     1861 gaaatcgcac aaggaggtac tacaggaaag agtgcccagt gtcctgaacc tgacagctag
     1921 ctgcactgct ttctttgtaa cgtaaagtga catgaagact cagttttgtt gggtactttg
     1981 aactgactaa tagcttgctc ttgattatat agtgaattaa taattaaaca agggaaaaaa
     2041 aaaaaggaaa gacctaagca attaaatcgt gcacttttct tcactgagac tgggaaagtt
     2101 tttatgttcc tacatgtaga aaaaccttgc tgcattttag ttttattttc aatcatttta
     2161 gctcttcttt cttgatctgt atttgattta ctgggatgag agaagttcag actctggagt
     2221 gtatcgtatg actggacaaa atgtggattg tgattgttgg atgtaaattt gtatgcttca
     2281 catggtgtgt gtgtttgatt tttaaaaagg gctgctttta cttcgggtac ttttaaggat
     2341 tgtaaataac aagtcaatca tcacagtgct ctttctgctg aatgatttta gggctaatag
     2401 tatggtaagg ttgcaaaaca gtggttttcg tatcatattt ggggccctgc tttaagatat
     2461 tacatattta ttgtttatgc tttttctgta taagctggtt gaactttgtt actcatctat
     2521 gctttggtaa gcagggatag aaaactaatc atgtctgact cagttcttta gtgctacaca
     2581 gcaggcttct gatagtggat gtaaatatat ttgaaagatg tttagtctca ccctcgatgc
     2641 agtgttttct ttgataggtt cttaatttta gtttttttta aggtcttcat tttgttttca
     2701 gtgttcaaat ataaaaatgg tgctaactgt aggatgtata acgaagctat aaccgatgtt
     2761 atttgggtgt ccaatgtgag atgcatgata cactttgatt agcgttttca ttgttacttg
     2821 tgcttgtgtt aatgattaca ttagtgttaa catc
//
