LOCUS       NP_001034150             604 aa            linear   ROD 28-APR-2025
DEFINITION  kelch-like protein 15 isoform a [Mus musculus].
ACCESSION   NP_001034150 XP_987109
VERSION     NP_001034150.1
DBSOURCE    REFSEQ: accession NM_001039061.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (residues 1 to 604)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
REFERENCE   2  (residues 1 to 604)
  AUTHORS   Diez-Roux,G., Banfi,S., Sultan,M., Geffers,L., Anand,S., Rozado,D.,
            Magen,A., Canidio,E., Pagani,M., Peluso,I., Lin-Marq,N., Koch,M.,
            Bilio,M., Cantiello,I., Verde,R., De Masi,C., Bianchi,S.A.,
            Cicchini,J., Perroud,E., Mehmeti,S., Dagand,E., Schrinner,S.,
            Nurnberger,A., Schmidt,K., Metz,K., Zwingmann,C., Brieske,N.,
            Springer,C., Hernandez,A.M., Herzog,S., Grabbe,F., Sieverding,C.,
            Fischer,B., Schrader,K., Brockmeyer,M., Dettmer,S., Helbig,C.,
            Alunni,V., Battaini,M.A., Mura,C., Henrichsen,C.N.,
            Garcia-Lopez,R., Echevarria,D., Puelles,E., Garcia-Calero,E.,
            Kruse,S., Uhr,M., Kauck,C., Feng,G., Milyaev,N., Ong,C.K.,
            Kumar,L., Lam,M., Semple,C.A., Gyenesei,A., Mundlos,S., Radelof,U.,
            Lehrach,H., Sarmientos,P., Reymond,A., Davidson,D.R., Dolle,P.,
            Antonarakis,S.E., Yaspo,M.L., Martinez,S., Baldock,R.A., Eichele,G.
            and Ballabio,A.
  TITLE     A high-resolution anatomical atlas of the transcriptome in the
            mouse embryo
  JOURNAL   PLoS Biol 9 (1), e1000582 (2011)
   PUBMED   21267068
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK081546.1, AK078112.1, AK133055.1 and AL646049.14.
            
            On Aug 25, 2006 this sequence version replaced XP_987109.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK078112.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849380
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..604
                     /organism="Mus musculus"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="X"
                     /map="X 41.53 cM"
     Protein         1..604
                     /product="kelch-like protein 15 isoform a"
                     /note="kelch-like protein 15"
                     /calculated_mol_wt=69614
     Region          1..137
                     /region_name="BTB_POZ_KLHL15"
                     /note="BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ
                     (poxvirus and zinc finger) domain found in Kelch-like
                     protein 15 (KLHL15); cd18244"
                     /db_xref="CDD:349553"
     Region          33..576
                     /region_name="PHA03098"
                     /note="kelch-like protein; Provisional"
                     /db_xref="CDD:222983"
     Region          128..235
                     /region_name="BACK_KLHL15"
                     /note="BACK (BTB and C-terminal Kelch) domain found in
                     Kelch-like protein 15 (KLHL15); cd18454"
                     /db_xref="CDD:350529"
     Region          321..365
                     /region_name="KELCH repeat"
                     /note="KELCH repeat [structural motif]"
                     /db_xref="CDD:276965"
     Region          328..379
                     /region_name="Kelch 1"
                     /note="propagated from UniProtKB/Swiss-Prot (A2AAX3.1)"
     Region          369..412
                     /region_name="KELCH repeat"
                     /note="KELCH repeat [structural motif]"
                     /db_xref="CDD:276965"
     Region          381..426
                     /region_name="Kelch 2"
                     /note="propagated from UniProtKB/Swiss-Prot (A2AAX3.1)"
     Region          417..474
                     /region_name="KELCH repeat"
                     /note="KELCH repeat [structural motif]"
                     /db_xref="CDD:276965"
     Region          428..473
                     /region_name="Kelch 3"
                     /note="propagated from UniProtKB/Swiss-Prot (A2AAX3.1)"
     Region          478..529
                     /region_name="KELCH repeat"
                     /note="KELCH repeat [structural motif]"
                     /db_xref="CDD:276965"
     Region          489..542
                     /region_name="Kelch 4"
                     /note="propagated from UniProtKB/Swiss-Prot (A2AAX3.1)"
     Region          532..572
                     /region_name="KELCH repeat"
                     /note="KELCH repeat [structural motif]"
                     /db_xref="CDD:276965"
     Region          544..590
                     /region_name="Kelch 5"
                     /note="propagated from UniProtKB/Swiss-Prot (A2AAX3.1)"
     CDS             1..604
                     /gene="Klhl15"
                     /gene_synonym="6330500C13Rik"
                     /coded_by="NM_001039061.1:499..2313"
                     /note="isoform a is encoded by transcript variant 1"
                     /db_xref="CCDS:CCDS30278.1"
                     /db_xref="GeneID:236904"
                     /db_xref="MGI:MGI:1923400"
ORIGIN      
        1 magdvegfcs sihdtsvsag fralyeegll ldvtlviedh qfqahkalla tqsdyfrimf
       61 tadmrerdqd kihlkgltat gfshvlqfmy ygtielsmnt vheilqaamy vqlievvkfc
      121 csfllakicl encaeimrll ddfgvniegv rekldaflld nfvplmsrpd flsylsfekl
      181 msyldndhls rfpeielyea vqswlrhdrr rwrhtdtiiq nirfclmtps svfekvktse
      241 fyrysrqlry evdqalnyfq nvhqqplldm kssrirsakp qttvfrgmig hsmvnskill
      301 lkkprvwwel egpqvplrpd claivnnfvf llggeelgpd gefhasskvf rydprqnswl
      361 rmadmsvprs efavgvigkf iyavagrtrd etfysteryd itndkwefvd pypvnkyghe
      421 gtvlnnklfi tggitsssts kqvcvfdpsk egtieqrtrr tqvvtncwen kskmnyarcf
      481 hkmisyngkl yvfggvcvil rasfesqgcp stevynpdtd qwtilasmpi grsghgvtvl
      541 dkqimvlggl cynghysdsi ltfdpdenkw kedeyprmpc kldglqvcnl hfpdyvldev
      601 rrcn
//
