LOCUS       NM_001381892            3284 bp    mRNA    linear   ROD 16-OCT-2024
DEFINITION  Mus musculus kelch-like 13 (Klhl13), transcript variant 5, mRNA.
ACCESSION   NM_001381892 XM_011247484
VERSION     NM_001381892.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3284)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3284)
  AUTHORS   Pulcrano,S., De Gregorio,R., De Sanctis,C., Volpicelli,F.,
            Piscitelli,R.M., Speranza,L., Perrone-Capano,C., di Porzio,U.,
            Caiazzo,M., Martini,A., Giacomet,C., Medina,D., Awatramani,R.,
            Viggiano,D., Federici,M., Mercuri,N.B., Guatteo,E. and
            Bellenchi,G.C.
  TITLE     miR-218 Promotes Dopaminergic Differentiation and Controls Neuron
            Excitability and Neurotransmitter Release through the Regulation of
            a Synaptic-Related Genes Network
  JOURNAL   J Neurosci 43 (48), 8104-8125 (2023)
   PUBMED   37816598
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3284)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 3284)
  AUTHORS   Duteil,D., Tosic,M., Lausecker,F., Nenseth,H.Z., Muller,J.M.,
            Urban,S., Willmann,D., Petroll,K., Messaddeq,N., Arrigoni,L.,
            Manke,T., Kornfeld,J.W., Bruning,J.C., Zagoriy,V., Meret,M.,
            Dengjel,J., Kanouni,T. and Schule,R.
  TITLE     Lsd1 Ablation Triggers Metabolic Reprogramming of Brown Adipose
            Tissue
  JOURNAL   Cell Rep 17 (4), 1008-1021 (2016)
   PUBMED   27760309
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL808116.6 and AL773552.6.
            
            On Apr 17, 2020 this sequence version replaced XM_011247484.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660813.1654.1,
                                           SRR11927936.2790177.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164139, SAMN01164141
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-108               AL808116.6         22291-22398         c
            109-199             AL808116.6         18829-18919         c
            200-271             AL773552.6         110967-111038       c
            272-337             AL773552.6         90052-90117         c
            338-476             AL773552.6         57272-57410         c
            477-609             AL773552.6         43949-44081         c
            610-806             AL773552.6         43198-43394         c
            807-1602            AL773552.6         31063-31858         c
            1603-1716           AL773552.6         24411-24524         c
            1717-3284           AL773552.6         15122-16689         c
FEATURES             Location/Qualifiers
     source          1..3284
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="X"
                     /map="X 17.22 cM"
     gene            1..3284
                     /gene="Klhl13"
                     /gene_synonym="1200009K10Rik; Bklhd2; D130072F20Rik"
                     /note="kelch-like 13"
                     /db_xref="GeneID:67455"
                     /db_xref="MGI:MGI:1914705"
     exon            1..108
                     /gene="Klhl13"
                     /gene_synonym="1200009K10Rik; Bklhd2; D130072F20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            109..199
                     /gene="Klhl13"
                     /gene_synonym="1200009K10Rik; Bklhd2; D130072F20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            200..271
                     /gene="Klhl13"
                     /gene_synonym="1200009K10Rik; Bklhd2; D130072F20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            272..337
                     /gene="Klhl13"
                     /gene_synonym="1200009K10Rik; Bklhd2; D130072F20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            338..476
                     /gene="Klhl13"
                     /gene_synonym="1200009K10Rik; Bklhd2; D130072F20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            477..609
                     /gene="Klhl13"
                     /gene_synonym="1200009K10Rik; Bklhd2; D130072F20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            610..806
                     /gene="Klhl13"
                     /gene_synonym="1200009K10Rik; Bklhd2; D130072F20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            807..1602
                     /gene="Klhl13"
                     /gene_synonym="1200009K10Rik; Bklhd2; D130072F20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1603..1716
                     /gene="Klhl13"
                     /gene_synonym="1200009K10Rik; Bklhd2; D130072F20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1717..3284
                     /gene="Klhl13"
                     /gene_synonym="1200009K10Rik; Bklhd2; D130072F20Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3265..3270
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Klhl13"
                     /gene_synonym="1200009K10Rik; Bklhd2; D130072F20Rik"
                     /note="hexamer: AATAAA"
     polyA_site      3284
                     /gene="Klhl13"
                     /gene_synonym="1200009K10Rik; Bklhd2; D130072F20Rik"
                     /note="major polyA site"
ORIGIN      
        1 gaggtcaggc ggaggctctg ccgctgcggc cgcagcagct cagctcccat tcccaggcag
       61 cttggaacag ggactttggc aaataactgg agcggcgttc gggttaggtt ctgaggcctt
      121 cagactggga ctgagctcca ccgccagcat ctccgacagc tttcagactg ccgtgggcct
      181 tctctgttgc cgcgactctg tctgctcaac cctgagaagt gatggatatt cttcacagag
      241 gagaattggt tgctgcaata ctccgcaacc ggagacggag gcaattgtct ttaaaacaag
      301 ccgatttcaa ggatatattc aaaaaggcag ctgcaggatc acttgtggaa gaggaagacc
      361 agcacttgaa actgtgcctt ggaagtgaaa tgggcctctc ttcccatttg cagtcttgca
      421 aggcaggaag tacacgcatc tttaccagca acagccacag ttctgtggtg ttacagggct
      481 ttgaccagct tcggcttgat ggattgcttt gtgatgtgac actgatgcca ggtgatacag
      541 atgatgctta ccctgtgcac agagtcatga tggcatctgc tagtgactac ttcaaagcta
      601 tgttcacagg tggaatgaaa gaacaagagc tgatgtgcat taagcttcat ggcgtgagca
      661 gagtgggtct acggaaaatt attgatttca tctatactgc aaagctttct cttaacatgg
      721 acacccttca ggatacgctg gaagccgcca gctttcttca gattcttccg gttttagact
      781 tctgcaaagt gtttctcata tctggggtca ctttggataa ctgtgttgaa gttggacgga
      841 ttgccaacac ctaccatctg acagaagtgg ataaatatgt caacagcttc gtcttaaaga
      901 attttgctgc attgctgagc actggggagt tcctgaagct tcccttcgag cgccttgcct
      961 ttgtcctgtc cagcaacagc cttaagcgct gcaccgaact tgacctcttc aaagctacct
     1021 gtcgctggct tcgcctggaa gaacctagaa tggacgttgc tgcaaaacta atgaagaata
     1081 tacgatttcc gctgatgaca ccacaggagc tcattaatta tgtgcaaacc gtggatttca
     1141 tgagaactga caatacttgc gtcaatttgc ttctggaagc cagcaattac caaatgatgc
     1201 cgtttatgca gccagttatg cagtcagaca ggactgccat tcggtctgac accactcgtt
     1261 tggttacact cggaggagtc ctgagacagc agcttgtcgt cagtaaagaa ttgcgcatgt
     1321 atgatgaaaa gacccacgag tggaaatctc tagcccccat ggatgcccca agataccagc
     1381 atggcattgc tgtcatcgga aattttctct acgttgttgg tgggcagagt aattatgaca
     1441 caaaaggaaa aaccgccgtc gatacagtgt ttagatttga tcctcgatac aacaaatgga
     1501 tccaagttgc atctttaaat gaaaagcgca ccttcttcca cctaagtgcc ctcaaaggat
     1561 ttctgtatgc agttggtgga cgaaatgcag ctggagaact ccctactgtg gaatgttaca
     1621 atccgagaac aaatgaatgg acctatgttg ccaaaatgaa tgaacctcac tatggccatg
     1681 ctggaactgt gtatggagga gtgatgtata tttcaggagg aattacccat gacactttcc
     1741 aaaaggagct catgtgcttc gaccctgata ctgacaaatg gacccagaag gcaccgatga
     1801 ccactgtccg aggcctacac tgcatgtgta cggtgggaga taggctctac gtcattggtg
     1861 gcaaccattt ccgaggaacc agtgattatg atgatgtcct gagctgtgaa tactactcac
     1921 ctatccttga ccagtggacc ccaattgctt ccatgttaag agggcagagt gatgttgggg
     1981 tcgctgtctt tgagaataaa atctatgtgg ttggtggcta ttcatggaat aatcgctgta
     2041 tggtagagat agtgcagaag tatgatccag agaaaaatga atggcataag gttttcgatc
     2101 tgccagagtc tcttggtggt attcgagctt gtacacttac agtttatcca cctgaagaag
     2161 ccacaccatc accttctaga gagtcccctc tttctggacc ctaagatcat ccttacaatt
     2221 aagatgctat attcctatct ttgcaatgtg tcatgattat cttcttttcc ccccttaagt
     2281 agcatatatg ttagagttag ccttcagtaa ttgatacaga aaaaaaattg acattgatgt
     2341 tacttgtgat gtttgtatgg cctagaatgt ttataaagtg gtaacaaacc atccttgaaa
     2401 tatatcccat agaagctgat gtttaacatg aaaacaaaaa aagtattgtc tacaaagtgt
     2461 ttcttcagta ctttctaaat gctgtgtact gagtgtaagg gattcctcat cttacattat
     2521 aagccaagtt gaaggtggat tatagtaaat gtacaactgt gctcactagg tttcaaagtg
     2581 aagaagtttt cctttcatct ttaactgtaa gatgtcaaag ggaggcagcc tgctccaata
     2641 ggaaacagta cacaaaaggt tgccaactcg catgagctac ctccctcttt tcataaagta
     2701 tttttgacac atctgtcaac ccacctgact gtgtgggtgc attgagaaca caccaagttt
     2761 ctaagacaca caggagaaat aactgaaatt caccaacact agtttgtggg ggaaagcatg
     2821 acccctctgc ttataagaat tggtttgggg ttttttttaa gtgtgtatag atgaacacac
     2881 acatacttat atcaaataca aatttttaaa aattgactgt caggtcaaat aaatgtgaaa
     2941 ttaaacaaaa ttcttctaaa aagcagcttc catgaaaaat ggggattcag tatgcacaca
     3001 ttaaatgcat atatttcaaa ccatactgaa tttaggtgga taagggctag aaattttgag
     3061 caactaaatt tatcacttga ccaaatttta ccataaagaa ttatattctc tttttctcct
     3121 ttgctgttga agtaacttac ctgttgtgtg gattctgtat tctgtacact cttggttcat
     3181 gaggttattt agcacaaagt gtaacagctt cacctgggaa gctgcttttg ctctatgatg
     3241 tccatggttt cccttctttt cttcaataaa aacatttaat gtca
//
