LOCUS       NM_033563               1344 bp    mRNA    linear   ROD 16-OCT-2024
DEFINITION  Mus musculus Kruppel-like transcription factor 7 (ubiquitous)
            (Klf7), mRNA.
ACCESSION   NM_033563 XM_992457 XM_992492 XM_992521
VERSION     NM_033563.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1344)
  AUTHORS   Kc,R., Lopez de Boer,R., Lin,M., Vagnozzi,A.N., Jeannotte,L. and
            Philippidou,P.
  TITLE     Multimodal Hox5 activity generates motor neuron diversity
  JOURNAL   Commun Biol 7 (1), 1166 (2024)
   PUBMED   39289460
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1344)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 1344)
  AUTHORS   Jiang,W., Lu,W., Liu,J., Ren,H., Zhao,X. and Yang,W.
  TITLE     miR-520f-3p blocks MNNG-induced gastric precancerous lesions via
            the KLF7/NFkappaB pathway
  JOURNAL   Toxicol Lett 392, 64-74 (2024)
   PUBMED   38184286
  REMARK    GeneRIF: miR-520f-3p blocks MNNG-induced gastric precancerous
            lesions via the KLF7/NFkappaB pathway.
REFERENCE   4  (bases 1 to 1344)
  AUTHORS   Yang,X., Liang,M., Tang,Y., Ma,D., Li,M., Yuan,C., Hou,Y., Sun,C.,
            Liu,J., Wei,Q., Chang,Y., Wang,C. and Zhang,J.
  TITLE     KLF7 promotes adipocyte inflammation and glucose metabolism
            disorder by activating the PKCzeta/NF-kappaB pathway
  JOURNAL   FASEB J 37 (7), e23033 (2023)
   PUBMED   37342904
  REMARK    GeneRIF: KLF7 promotes adipocyte inflammation and glucose
            metabolism disorder by activating the PKCzeta/NF-kappaB pathway.
REFERENCE   5  (bases 1 to 1344)
  AUTHORS   Wang,C., Qiao,S., Zhao,Y., Tian,H., Yan,W., Hou,X., Wang,R.,
            Zhang,B., Yang,C., Zhu,F., Jiao,Y., Jin,J., Chen,Y. and Tian,W.
  TITLE     The KLF7/PFKL/ACADL axis modulates cardiac metabolic remodelling
            during cardiac hypertrophy in male mice
  JOURNAL   Nat Commun 14 (1), 959 (2023)
   PUBMED   36810848
  REMARK    GeneRIF: The KLF7/PFKL/ACADL axis modulates cardiac metabolic
            remodelling during cardiac hypertrophy in male mice.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 1344)
  AUTHORS   Lei,L., Laub,F., Lush,M., Romero,M., Zhou,J., Luikart,B.,
            Klesse,L., Ramirez,F. and Parada,L.F.
  TITLE     The zinc finger transcription factor Klf7 is required for TrkA gene
            expression and development of nociceptive sensory neurons
  JOURNAL   Genes Dev 19 (11), 1354-1364 (2005)
   PUBMED   15937222
  REMARK    GeneRIF: Klf7 gene ablation reduces TrkA expression in sensory
            neurons due to effect on cell death
REFERENCE   7  (bases 1 to 1344)
  AUTHORS   Suske,G., Bruford,E. and Philipsen,S.
  TITLE     Mammalian SP/KLF transcription factors: bring in the family
  JOURNAL   Genomics 85 (5), 551-556 (2005)
   PUBMED   15820306
REFERENCE   8  (bases 1 to 1344)
  AUTHORS   Smaldone,S., Laub,F., Else,C., Dragomir,C. and Ramirez,F.
  TITLE     Identification of MoKA, a novel F-box protein that modulates
            Kruppel-like transcription factor 7 activity
  JOURNAL   Mol Cell Biol 24 (3), 1058-1069 (2004)
   PUBMED   14729953
REFERENCE   9  (bases 1 to 1344)
  AUTHORS   Laub,F., Aldabe,R., Friedrich,V. Jr., Ohnishi,S., Yoshida,T. and
            Ramirez,F.
  TITLE     Developmental expression of mouse Kruppel-like transcription factor
            KLF7 suggests a potential role in neurogenesis
  JOURNAL   Dev Biol 233 (2), 305-318 (2001)
   PUBMED   11336497
REFERENCE   10 (bases 1 to 1344)
  AUTHORS   Lei,L., Ma,L., Nef,S., Thai,T. and Parada,L.F.
  TITLE     mKlf7, a potential transcriptional regulator of TrkA nerve growth
            factor receptor expression in sensory and sympathetic neurons
  JOURNAL   Development 128 (7), 1147-1158 (2001)
   PUBMED   11245580
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC019604.1.
            
            On or before May 4, 2006 this sequence version replaced
            XM_992492.1, XM_992521.1, XM_992457.1, NM_033563.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC019604.1, AF338369.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164138, SAMN01164139
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1344
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="FVB/N"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 32.31 cM"
     gene            1..1344
                     /gene="Klf7"
                     /gene_synonym="9830124P08Rik"
                     /note="Kruppel-like transcription factor 7 (ubiquitous)"
                     /db_xref="GeneID:93691"
                     /db_xref="MGI:MGI:1935151"
     exon            1..490
                     /gene="Klf7"
                     /gene_synonym="9830124P08Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             389..1294
                     /gene="Klf7"
                     /gene_synonym="9830124P08Rik"
                     /note="Kruppel-like factor 7 (ubiquitous)"
                     /codon_start=1
                     /product="Krueppel-like factor 7"
                     /protein_id="NP_291041.2"
                     /db_xref="CCDS:CCDS15003.1"
                     /db_xref="GeneID:93691"
                     /db_xref="MGI:MGI:1935151"
                     /translation="MDVLASYSIFQELQLVHDTGYFSALPSLEETWQQTCLELERYLQ
                     TEPRRISETFGEDLDCFLHASPPPCIEESFRRLDPLLLPVEATICEKSSAVDILLSRD
                     KLLSETCLSLQPTSSSLDSYTAVNQAQLNAVTSLTPPSSPELSRHLVKTSQTLSAVDG
                     TVTLKLVAKKASLSSVKVGGVAAAAAVTPAGAVKSGQSDSEQGGGGADTCPENKKRVH
                     RCQFNGCRKVYTKSSHLKAHQRTHTGEKPYKCSWEGCEWRFARSDELTRHYRKHTGAK
                     PFKCNHCDRCFSRSDHLALHMKRHI"
     exon            491..1118
                     /gene="Klf7"
                     /gene_synonym="9830124P08Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1119..1242
                     /gene="Klf7"
                     /gene_synonym="9830124P08Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1243..1344
                     /gene="Klf7"
                     /gene_synonym="9830124P08Rik"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtcagtgagt ttgcgttccc cttcctgatc cacgcgctgg agtgattaga gccctggaag
       61 ggaattgtta ctcccgtgaa gtcccctttt cctggcagtc atctgcactg tacacgctgg
      121 atccctctct ccgatccacc ccactcactc gctcctctct cacctcctct ctcacctcct
      181 ctctctccct cctctctcac ctcctctctc cctctctcct gcattgattt tttttctctc
      241 ctttttttag ttgactgaaa caaaacaaaa caaaagggcc actggatgtc tgccttcttg
      301 gggggtgagc cagacagact gacaaacaaa cagacccagc tgagctcggg ggagggtttc
      361 tcctccggtt ttgcccggca gcagcagcat ggacgtgttg gctagttata gtatattcca
      421 ggagctacaa cttgtccacg acaccggcta cttctcagct ttgccatccc tggaggagac
      481 ctggcagcag acatgccttg agttggaacg ctacctccag acagaacccc ggcggatctc
      541 ggagaccttt ggtgaggact tggactgctt cctccacgct tctcctcccc catgcattga
      601 ggagagcttc cggcgcctag accccttgct gctcccagtg gaagccacca tctgcgagaa
      661 gagctccgca gtggacattt tgctctctcg ggacaagttg ctatctgaga cctgcctcag
      721 cctccagcca accagctctt ctctagacag ctacacagcc gtcaaccagg cccagctcaa
      781 cgcagtgacc tcattaacgc cgccctcatc ccctgagctc agccgccatc tggtcaaaac
      841 ctcacagact ctctcagccg tggatggcac agtgacgttg aaactggtgg ccaagaaggc
      901 ttccctcagc tcggtgaagg tgggaggggt ggcggcggcg gcagccgtga caccagctgg
      961 agcagttaag agtggacaga gcgacagtga gcaaggaggg ggaggggctg acacatgccc
     1021 tgaaaacaag aagagggtcc atcgctgtca gtttaacggg tgccggaaag tttatacaaa
     1081 aagctcccac ttaaaggccc accagaggac tcacacaggt gagaagcctt acaagtgctc
     1141 atgggaagga tgcgagtggc gttttgcacg gagcgatgag ctcacaaggc actacaggaa
     1201 acacacaggt gcaaagccct ttaagtgtaa ccactgcgac aggtgtttct ccaggtctga
     1261 ccatcttgcg ctccatatga agagacatat ctaaacaaaa caaaacaaga caaaataaaa
     1321 acaaacaaaa gtaaaaaaaa aaaa
//
