LOCUS       NM_010636              10424 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus Kruppel-like transcription factor 12 (Klf12),
            transcript variant 1, mRNA.
ACCESSION   NM_010636 XM_006518623
VERSION     NM_010636.4
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 10424)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 10424)
  AUTHORS   Pan,X., Zhang,W., Wang,L., Guo,H., Zheng,M., Wu,H., Weng,Q., He,Q.,
            Ding,L. and Yang,B.
  TITLE     KLF12 transcriptionally regulates PD-L1 expression in non-small
            cell lung cancer
  JOURNAL   Mol Oncol 17 (12), 2659-2674 (2023)
   PUBMED   37606530
  REMARK    GeneRIF: KLF12 transcriptionally regulates PD-L1 expression in
            non-small cell lung cancer.
REFERENCE   3  (bases 1 to 10424)
  AUTHORS   Liu,Y., Yuan,Q., Wang,Z., Ding,L., Kong,N., Liu,J., Hu,Y.,
            Zhang,Y., Li,C., Yan,G., Jiang,Y. and Sun,H.
  TITLE     A high level of KLF12 causes folic acid-resistant neural tube
            defects by activating the Shh signaling pathway in micedagger
  JOURNAL   Biol Reprod 105 (4), 837-845 (2021)
   PUBMED   34104947
  REMARK    GeneRIF: A high level of KLF12 causes folic acid-resistant neural
            tube defects by activating the Shh signaling pathway in micedagger.
REFERENCE   4  (bases 1 to 10424)
  AUTHORS   Lam,V.C., Folkersen,L., Aguilar,O.A. and Lanier,L.L.
  TITLE     KLF12 Regulates Mouse NK Cell Proliferation
  JOURNAL   J Immunol 203 (4), 981-989 (2019)
   PUBMED   31300511
  REMARK    GeneRIF: we found that KLF12 regulates mouse NK cell proliferation
REFERENCE   5  (bases 1 to 10424)
  AUTHORS   Shin,Y., Kim,D.Y., Ko,J.Y., Woo,Y.M. and Park,J.H.
  TITLE     Regulation of KLF12 by microRNA-20b and microRNA-106a in
            cystogenesis
  JOURNAL   FASEB J 32 (7), 3574-3582 (2018)
   PUBMED   29475398
  REMARK    GeneRIF: Klf12 expression is down-regulated in kidney tissues of
            Pkd2f/f mice.  miR-20b-5p and miR-106a-5p directly target Klf12
            mRNA by binding to the 3'-UTR of Klf12.
REFERENCE   6  (bases 1 to 10424)
  AUTHORS   Piao,Y., Ko,N.T., Lim,M.K. and Ko,M.S.
  TITLE     Construction of long-transcript enriched cDNA libraries from
            submicrogram amounts of total RNAs by a universal PCR amplification
            method
  JOURNAL   Genome Res 11 (9), 1553-1558 (2001)
   PUBMED   11544199
REFERENCE   7  (bases 1 to 10424)
  AUTHORS   Roth,C., Schuierer,M., Gunther,K. and Buettner,R.
  TITLE     Genomic structure and DNA binding properties of the human zinc
            finger transcriptional repressor AP-2rep (KLF12)
  JOURNAL   Genomics 63 (3), 384-390 (2000)
   PUBMED   10704285
REFERENCE   8  (bases 1 to 10424)
  AUTHORS   Araki,K., Imaizumi,T., Sekimoto,T., Yoshinobu,K., Yoshimuta,J.,
            Akizuki,M., Miura,K., Araki,M. and Yamamura,K.
  TITLE     Exchangeable gene trap using the Cre/mutated lox system
  JOURNAL   Cell Mol Biol (Noisy-le-grand) 45 (5), 737-750 (1999)
   PUBMED   10512203
REFERENCE   9  (bases 1 to 10424)
  AUTHORS   Turner,J. and Crossley,M.
  TITLE     Mammalian Kruppel-like transcription factors: more than just a
            pretty finger
  JOURNAL   Trends Biochem Sci 24 (6), 236-240 (1999)
   PUBMED   10366853
  REMARK    Review article
REFERENCE   10 (bases 1 to 10424)
  AUTHORS   Imhof,A., Schuierer,M., Werner,O., Moser,M., Roth,C., Bauer,R. and
            Buettner,R.
  TITLE     Transcriptional regulation of the AP-2alpha promoter by BTEB-1 and
            AP-2rep, a novel wt-1/egr-related zinc finger repressor
  JOURNAL   Mol Cell Biol 19 (1), 194-204 (1999)
   PUBMED   9858544
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC125446.12, AC116856.8, AC117638.13 and AC113486.11.
            
            On or before Aug 31, 2022 this sequence version replaced
            XM_006518623.5, NM_010636.3.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR10223969.15798.1,
                                           SRR10223970.17224.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164138
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-232               AC125446.12        94715-94946         c
            233-296             AC116856.8         73766-73829
            297-386             AC116856.8         113701-113790
            387-933             AC117638.13        47412-47958
            934-1069            AC117638.13        83014-83149
            1070-1132           AC117638.13        128484-128546
            1133-1290           AC113486.11        33704-33861
            1291-10424          AC113486.11        58629-67762
FEATURES             Location/Qualifiers
     source          1..10424
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="14"
                     /map="14 50.9 cM"
     gene            1..10424
                     /gene="Klf12"
                     /gene_synonym="2700063E05Rik; AP-2rep; B130052C06Rik;
                     D530033K05Rik"
                     /note="Kruppel-like transcription factor 12"
                     /db_xref="GeneID:16597"
                     /db_xref="MGI:MGI:1333796"
     exon            1..232
                     /gene="Klf12"
                     /gene_synonym="2700063E05Rik; AP-2rep; B130052C06Rik;
                     D530033K05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            233..296
                     /gene="Klf12"
                     /gene_synonym="2700063E05Rik; AP-2rep; B130052C06Rik;
                     D530033K05Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             264..1472
                     /gene="Klf12"
                     /gene_synonym="2700063E05Rik; AP-2rep; B130052C06Rik;
                     D530033K05Rik"
                     /note="transcriptional repressor AP-2rep; Kruppel-like
                     factor 12"
                     /codon_start=1
                     /product="Krueppel-like factor 12"
                     /protein_id="NP_034766.2"
                     /db_xref="CCDS:CCDS36998.1"
                     /db_xref="GeneID:16597"
                     /db_xref="MGI:MGI:1333796"
                     /translation="MNIHMKRKTIKNLSALENRMLMLDGMPAVRVKTELVESEQGSPN
                     VHNYPDMEAVPLLLNNVKGEPPEDSLPVDHFQTQTEPVDLSINKARTSPTAASSSPVS
                     MTASASSPSSTSTSSSSSSRPASSPTVITSVSSASSSSTVLSPGPLVASASGVGGQQF
                     LHIIHPVPPSSPMNLQSNKLSHVHRIPVVVQSVPVVYTAVRSPGNVNNTIVVPLLEDG
                     RSHGKAQMEPRGLSPRQSKSDSDDDDLPNVTLDSVNETGSTALSIARAVQEVHPSPVS
                     RVRGNRMNNQKFACSISPFSIESTRRQRRSESPDSRKRRIHRCDFEGCNKVYTKSSHL
                     KAHRRTHTGEKPYKCTWEGCTWKFARSDELTRHYRKHTGVKPFKCADCDRSFSRSDHL
                     ALHRRRHMLV"
     exon            297..386
                     /gene="Klf12"
                     /gene_synonym="2700063E05Rik; AP-2rep; B130052C06Rik;
                     D530033K05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            387..933
                     /gene="Klf12"
                     /gene_synonym="2700063E05Rik; AP-2rep; B130052C06Rik;
                     D530033K05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            934..1069
                     /gene="Klf12"
                     /gene_synonym="2700063E05Rik; AP-2rep; B130052C06Rik;
                     D530033K05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1070..1132
                     /gene="Klf12"
                     /gene_synonym="2700063E05Rik; AP-2rep; B130052C06Rik;
                     D530033K05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1133..1290
                     /gene="Klf12"
                     /gene_synonym="2700063E05Rik; AP-2rep; B130052C06Rik;
                     D530033K05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1291..10424
                     /gene="Klf12"
                     /gene_synonym="2700063E05Rik; AP-2rep; B130052C06Rik;
                     D530033K05Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      10404..10409
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Klf12"
                     /gene_synonym="2700063E05Rik; AP-2rep; B130052C06Rik;
                     D530033K05Rik"
                     /note="hexamer: AATAAA"
     polyA_site      10424
                     /gene="Klf12"
                     /gene_synonym="2700063E05Rik; AP-2rep; B130052C06Rik;
                     D530033K05Rik"
                     /note="major polyA site"
ORIGIN      
        1 attcatttcc tgagaactgc agagagcagc tgagaggctc tgcttgtgcg tgtgcgtgtg
       61 agtgtgcgcg ggtgacgccg tgtgagtgtg tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg
      121 agtgtgtgcg cgagtgtgcg cgcgcgcgtg tgagagagaa agggcgagag agagggggac
      181 tcttgtgtga gggaaagaaa acaatttctc ctgctctgca gcttctgttc aggatcaatg
      241 tgactctaga aacaaatgga tgaatgaata tccatatgaa gaggaaaacc ataaagaatc
      301 tcagcgccct tgagaacaga atgctaatgc ttgatggaat gccggcagtc agagtcaaaa
      361 ccgagcttgt ggaatctgaa caagggtctc caaacgtcca caactacccc gatatggaag
      421 ctgtccccct cttgctaaat aatgtgaaag gggagccccc agaggactca ctgcctgtag
      481 atcactttca gacacaaact gagccagtgg acttgtcaat caacaaagcc aggacctccc
      541 ctactgcagc gtcatcctcc cctgtctcca tgacagcgtc cgcctcctca ccttcttcaa
      601 cttcaacctc ttcatcctct tctagtcgtc cagcctcatc ccccactgtt ataacatcag
      661 tatcttcagc atcgtcttcg tcaacagtgt tatctccagg accccttgtt gcctctgcat
      721 ctggcgtggg cggccagcag ttcttgcaca tcatccatcc ggtcccacct tccagtccca
      781 tgaacttaca gtctaacaaa ctcagtcatg ttcatcgaat ccctgtggtg gtacagtcag
      841 tgccggttgt ctacacagct gtacggtcac ctggaaatgt gaacaacact attgttgtac
      901 cgctcctgga ggatgggagg agccatggca aagcacaaat ggagccccga ggcctatctc
      961 ccagacagag taaaagtgac agtgacgatg atgacctgcc aaatgtgacc ttagatagcg
     1021 ttaatgaaac tggatccacg gccctttcca tagccagagc agtacaagag gtacatccat
     1081 ccccggtatc cagggtccga ggaaatcgaa tgaataacca gaagtttgct tgttcaatct
     1141 caccatttag cattgagagc acaagacgcc agagacgatc agaatcccca gactccagga
     1201 aacggcgcat ccacagatgt gacttcgaag ggtgcaacaa agtctataca aaaagttctc
     1261 acctgaaggc acaccggaga acacacacag gagagaagcc ctacaaatgc acgtgggaag
     1321 gctgcacctg gaagtttgcc cgttcagatg aactgaccag acactaccgc aaacacacgg
     1381 gagtgaagcc attcaagtgc gcggactgtg accgcagctt ctcgaggtca gaccacctgg
     1441 cactgcaccg taggaggcac atgctggtgt gaggaaggct ccggtccagc tacgtgcaag
     1501 agctgggtct cttcaggagc aactaactca gcagggctga gctccctcta cagtgttaac
     1561 gtcaagggca ccgccattcc cacggtgcct gaaaccagag caggaacaag aaggaaccct
     1621 tctcccttcg gcctgaaggt aaccccccat catgaccaca cgcgtgagag agccgtctgc
     1681 gttcacgctg gcctgggagt tcagcgcctc aggtcctgaa gagacaggca ttgttttcca
     1741 tgctatgtcc tctgccattg aaaagatgtt tgtagcttgt acattttctg agctggcaga
     1801 cactctgcta tcagtccctt taaaggtcat ctaccgcaaa ttgatggtta gaggagacct
     1861 tctcagtttg gatgattctt cctttccacc ctcaccctaa ccctagcccc ttttgacaac
     1921 gatttcagtt cctatctcag taagctagaa cacacaccca gtctgttacc agcaagcagc
     1981 atggactaga aaggaagggg ctattggagg cactctgtta cccaaaaaca aaggcacaca
     2041 gaagtagccc tctgtgctag atagcgctca taccttgtcc tcatgccatc ccccaaaaga
     2101 accaacattg agtcttttca tttgtttgtt gttgcttgtt tctgttctgt ttctattctg
     2161 tttttgtgca tcagttccag cagaggggca gagcagtttc tcaaagacta gtcctgctcc
     2221 gccctggcat ggactgacag agtattccgt agttgaatag gaagagcctg tctaaataat
     2281 aataacaata ataataacta ctgtcccact tcaaattgcg gtgttctgtc acctaggcac
     2341 catctcctcc tgcccttagt gtttgattac aaagaatcga ggagaggggg gctttcttag
     2401 acacactggc accacggtaa gaggtggagc tgcccaggca aagtcactga acatgaaaac
     2461 gagacaaagc agagatggaa ataatgctct tcttgaggag aaaagcaata atgaatagaa
     2521 ggactttcct acaataactc cactgaggac tcacattacc gattttcata cttactaaag
     2581 ggattgtaaa aaacacccca gcatctcaga ggtcttagtt acagccacag cacggaggta
     2641 atctttccac tttctgttgt cctacttgct taagtaccac acttagagat tatgctcccc
     2701 acttcttggt aggaaacagt tacttggtga ctagagaggc acaggaggca gagctgccga
     2761 tgaactcttc cgcctgtggg tctcttctgc ttgggcctga gtccgtggca agagtgtccc
     2821 catgggaagc ctggcaagag tgtccccatg ggaagcctgc cttggtgcta cttctccaac
     2881 ctggagagcc gagagtctga ctctacgcca ttcacttttt aaactgtccc agaatccccg
     2941 tgctcccaca ttggcatcca cagggacaga ccacctgctt cttctgggag aagggtcaga
     3001 gcaaagctag gttccatcct atctctcaag taaagagctt tttgtattta gcgaaatgta
     3061 caggaaaagc aatatatccc cccaaccccc caacaagcac tctttccaaa atagtctgtc
     3121 accactgaaa gctgctgttt tcccagcttt ctgtggcaaa ttgggtttgg tgagattttt
     3181 gttgttaaga cattttatag cttaaatatt aaaggtctcc agtgaaggcc tttgcaatat
     3241 atttcaatga cacacttgat ttgggaaact gcacaaatca acctcatagg gttcctagct
     3301 cagttttgaa tgtctgcaca ttctaaaatg atttctggtg acagttatcc ttcctagtat
     3361 cagcttctaa tcaggataat tgtattctga caaagcaaga gctatgaaca ttacaaggag
     3421 aaccatttgt gtcgggtagc tttgaaaaag acttttaata actgttcagg caaaagtagc
     3481 atgatttaca ggtcaagtcc cagcttcaga gatctgtgct ctacattttc tgccaggtat
     3541 aaaaacttca tcaggcaatt tccctcctcc aagggctgta gttctattga taaatagctt
     3601 cagctacaca ggttggtacc caccagccag caggattttt tggttattgc tttttgttgt
     3661 tattttttta tatatatacc aactggaaca tttttaaatc tgtactgtat gcacttccta
     3721 cttctcattg cctgtaatca tccagaataa aaccaggttt cctgatgcac gccagcatta
     3781 gtaactggcc agggcaaaga accctgacag tggcaaacaa gcaggatccc ccaggcgctg
     3841 gccctagagc ctaattgata ggtcgtaagg aagtcgctca agtcaagtac acggttggct
     3901 tagttctgtc tgctctcgta ggagccagtc ctttctccac tgagaaagca tcttgccagt
     3961 tttacaggga gaattcactg atctgacaag ccagggaagc ttcctgactg acatcttaat
     4021 ttaaatttag cacagaacta agagagtcgt acctctctag cagcataagg aagatgtggg
     4081 gaagtgagct cttcccccct cgctccctga aaatggaaag catactgaga tggtaaggta
     4141 acggatgaaa cctgccacca ttacaacgtt tccctcttct tgacatagcg atatttttag
     4201 aagagttgca agcacaaatg aacacatccc tgatctggcc caagaactga gacttatttg
     4261 gcactcgtct ggaggacgta accaatcctc cgcagtaagt ttccgaggtg tgttcccctt
     4321 ataacagaaa gtggtttgag actaaaggaa atgggatatc cttagtcaca gaaaagccac
     4381 cacccatttc atcgtccagt ctagcttctt gaaaagcaca gtgtatgata agctatcaaa
     4441 aagaaaaaga gagagagaga gaaccctaaa gcacctctca gtggtttcct aagcatgctt
     4501 tggtttcagg tttgaagtgg ttcatcttgc agctaggaag ggtgtgtgtg tttgggaaca
     4561 cctcgcacac acacagtggg gagaaccaat tgtctccttg aaatgtaaaa gctgatgaca
     4621 agggaggtgg gctattaggg gttttcagag agtcccttat aaggttacat aaataaaacg
     4681 agcactttta aatatcactt taaagattaa aagggaaaca agattagtga aggggggggg
     4741 ctttcaaaat gcttctgtgt ttacagacaa gggttgtagg tgattagaaa ggccatgttc
     4801 atcatggttg aaatttggaa cagctcatgt gaagactgtg tacgctttca tgcaacttgt
     4861 ttaatgtcag actgccattc gagtctggac tggaaatgga actctgcact ttgagatcag
     4921 ctcattagaa tgataacgtg tatatggata aagatgcagt attccttagt ctgtgctttg
     4981 tttattatct gtaccaaagc tgcaattgaa tagatccggt gaggggaggc cttcagttgt
     5041 aatcacatgc cgttgttttg ttgtagtgac tgcctagaaa cgttgctgag atattgttag
     5101 gaggctgtcc agttccttgt attgtgagga ttcttagaat tgaagcagtg ttaataccag
     5161 cacacacaca gtctgcatag aaaggatcga atgtgagtta atgctggcga accacatagg
     5221 cccaggaagc cttaatactc atagctcaaa tcagagttta ttctttacca ttgcctgtaa
     5281 gtgtatcacg taaatgtagg ccaccggcca gctctctctc tctccctttc ctgaggttgt
     5341 atatcccaca aaaatgtttt cagattgact tggctcagct aaggaaagag ggttggctgg
     5401 ccatgtcttc catattccac gtctacttgt tcccacactg cctttcactt atctggacag
     5461 tcacccgcaa cacatgcacc tgtgtgcaca catctgtata tgcagcagcc agcaggcaag
     5521 caaatatcaa caaagacctt tttttaaaga aataatttgt aataatccat cctatgtaga
     5581 aatgtaagtt attacccaac tagagaatca gcttataata ctatgtaact ttgcctgcgt
     5641 tttatagtta agaaatgtat ataaaaaatc taaaatgcta tattttcaca atttcattat
     5701 agagtaatgt gtgtttagca acccatgccc attggtattt taaatatgct aaatattgaa
     5761 caattgcaat agaaattcag attttcataa gaaaataaaa cagaaggata ctgcatcttt
     5821 aaaaaacaga gtgacgctat tttactgtat tcgtaacata tgtgatagtg gaaaagtatt
     5881 ttcaaacatg caaattttac agaggttgta aatagtttga tgacgtatgt tggggaaaag
     5941 cttctagttt tcatcacaat aaaaaaaaaa aaaccacttg ttcagatatg ccttgtgtat
     6001 ggatgataca cacaattagc aatgttgcca tgggaactgg ttccacttgt tgatgttctt
     6061 ggtgcttggc tagagctgag tggccacttg tcatggtgta gccagaatga tttgaaactc
     6121 aaatgaagtc acgttttcaa acttgtcatg tctttttctt gggactgaaa aagtgaggac
     6181 ttacttgttc tagaaagaat catatagcaa tcatcattct cccctctcac tgatctttgt
     6241 cctcaacaag atggttttca attgagaaaa caaaatgaaa tacaggtatt tctttcttgt
     6301 gtaggttcca gagggattgt tctctggtct aggcgtaggt cgatgaggtt aagtgtatgg
     6361 atatggccac atagtaaaag attctgcagt ggcaacagga aaaaggtaat gcccattttt
     6421 cagaaatgaa ttaaacgctg aaagtgcctg tcaatgaatg tgaccaatga gataatcctg
     6481 tactttcaca cagcaataat tatttattat acatggtttt tcctacacag tttgagagct
     6541 ctctctttct ctctctctct ctgtccctcc ctcctcctcc acacacacat aggaaagaaa
     6601 tgcacatagg aaattaaatc tgttcacgca aacccacaga agagggcttt catcactttg
     6661 aagtataacg aatctgattt gcaatttact atctcttcat tccatctttc ttacttgaat
     6721 ataagcaggc gatatatatg gagattaagg ttatctttag cgttcacgac aattataatg
     6781 ttcagataaa agtttgactg tgatgaacct cagacttacg acagagcacg tatagctcag
     6841 acaggcttgc tctgttaaaa acaccaacat acttggagca gatttgtaag ggattttttt
     6901 tgtctgcttt attttaccca cttagctcgg tgcacaagtc catccttatg tgctccattc
     6961 tcttttcatc tgacatgtac cctcgcacca tcaaggagca tctagagatg cacattgaca
     7021 aattatccct ctcttccccc aaaaagtcct cggatacttg tgaaggcctt cagacaggta
     7081 tttagttaat cctgacagtt acctcacgat gtacaatcag acgcttataa gctcttttct
     7141 aaaattattt tatagctaca agtagagtca ggggtagaaa tgagactgta tatagacatg
     7201 atcccagcct cttctccagc cttgctcttt caaagcatga atccacccag acaagctgtt
     7261 gaggctacgt gaaacgctgt actctttcag agccaaatac tcggtaagaa cagctcttaa
     7321 cgtatggcgg tgattacaca gtcaggtttt agacggcgta tgatactgga gcagaatagc
     7381 agtctccggg tcccatactc aggtggagaa aagcatccac tgttcaccct actttgtttt
     7441 aaaaatgaag ggtgaataca aatgattcag tgggtagatg ggaaaaccaa acaggtgcca
     7501 tgtcaaagca cagctactgt ggtccctggt ctcactgaag tcaaaccttc tttccccatg
     7561 ttgtctgaat gtgctaaagc atcccttaag gttcaaagct ccgtgcacgg gggcgggggg
     7621 ggggggggac gatagctact cctaattaat tccatgtgct gactgctaca ctaagaattc
     7681 gaatattacc tcccatctct acaaccattc tccagttgat ggatgagaaa ctgaggcaca
     7741 acaggaatgg ctgagatgtc caagggtaca gaataagtgg gtagagtggg aatacatatc
     7801 ctccgggctc tgcagcctgt attgtaggca cacccctgtt ccctattcct gtctgcacat
     7861 tcccggtctc ttactcagtt ttgttctgag ggccctgcgg gggtaaataa aagaacgtcc
     7921 cctagcacac agtgtgacta tagtagagaa gattttagat cagaaccttc ctggaaagtc
     7981 accgatggat ggccattctg gacaaacatt gaaccagaga tctccctaaa cttggcactt
     8041 tcattcatag gtttgcccag agcctctaag attttcaaaa cctttcttac ttcccattac
     8101 aatttagtcc cagttagttt tcctcaattt acatatttcc ttttccctaa cagacctgct
     8161 ctaatctgtg aaagggcatg tgagaccctc acctgagtaa agctacttct taactgcaga
     8221 ggccactctt acaggtagac aggtcccttc caggcctcac ttaacagcac tgcctcggaa
     8281 tgttttaaat agtctcataa ataatttgct tacagtattg ttagtttgag ttttatgtga
     8341 ggagctgtct aacatcagag caatgaaatc cctccctgtc tgcatagaag gtctctgaca
     8401 gtattgattc atggatgcac taatggactt tgaaaacatt aacaatgcca tttctcagag
     8461 tgtttcagtt tgtgaaaatg aatctcctaa attatgatct ttctccctgt tagttggctg
     8521 ggggaagaga taaaagctat ataaacaact tctcttccat gctgaaagca agggtctatg
     8581 tccacagcct ccttgtagat ggggactctg gtcacttaat tgagtttcaa caattacttc
     8641 tcagatgaca atgccaccac cctaagtggg ttgacaagtg ggaagagtca catcaataac
     8701 cttttttccc ccctgaattt catctctaga aatgtgaagt gtttcagtga tgctagttat
     8761 gaattatttt tttttcaaat gcaggtgcag ccaagtcctt gacagagatt aatctttgtt
     8821 gagaaatgag ggtttataag agagaattcc tctccaattc tactagtaaa agtgtccagt
     8881 caatcaaaaa ggaagatatt ttaggaatat tttgacatct cccttttatg ctcattttgt
     8941 tctctaaaaa tacaacataa aacatgacag atgtgttttt ttcccaactc atgtttctag
     9001 gttccttgtg gcaggatttt gtgattgttt ccagaccata gactatattc tgttcctcaa
     9061 attattacat tcagtaggta tcgttgaacc aggcactggt gcttacatgc aaggctcttt
     9121 cctatcaact tgtgtgtgtg caacttgttg tgtttgaagg ttcatctttg aaagccatcg
     9181 tctcccgcca tggaatggca gttgtattgt tttgtccatg tctatgtggg acacattgca
     9241 tcccatggca aagcaactat aaatggatgt gagataacga attaacaaaa ccagcttgaa
     9301 aacattgtct tctgtattac atcatcctgc ctcataatgc aattatgtgt atcatgatca
     9361 ccttttacaa agagaaacca gcaaattcat gtttgtccat agaagggtgt actaggaatt
     9421 gtctgtgttg tgaaactatg agaacagacc acctttaata tatccacctg ccacttaaaa
     9481 tgacttagtt ataattagta gtagtctaga cgttgctctt ggtgtgtggg ggtcagtgca
     9541 gacatcataa tcctttgaat aagcctccca gtcatatctg aaaaaacaca cacacacaca
     9601 catgagaata aagaaaaaca tcatctttgt ccaaatcaag caggcatctc tttgcttttc
     9661 ctcaatactg agctcattac acatggtgat tggatcacaa gatctgtgta aaatacaaaa
     9721 atgtcgttta cttatgctag gctggaaacc tctgcatggg aaagtgaata gatgagctgc
     9781 ttctggttca tatctatggg tgtaatctta caaaaagact cttggtcatg tgacccagac
     9841 agttggagtg cccagaggaa agcctacata ttaaagaata aaatcccccg aggaggctgg
     9901 caagcaaatg tgttgagttc ttaaatcttt gttcggtttt tctgttcaga gttttaattg
     9961 caaatgaatt tatttcttca gcttaaagat ctaatttcct aatagtttcc tccgcattta
    10021 tatactctgt agtgtttagg cagctcctgt tataagttta ttaatattat gtaagtgttg
    10081 ttcttgtatt tatgtatagt gtatgtattg taaatatact cagagctttt cctttttact
    10141 gtaaaatggt gatttttttt tgccctatga taatgaaaag agagactctc ctaatgaggt
    10201 tctctcagaa gattattcca gtctattctc agagatttaa atgaacaagt gttatcgttt
    10261 tcaatggtgt ctcagacata ttctgttggt gcatcgcttt tctgtattca actttcctat
    10321 gaattgagct gtgaactgaa atagagttta aacctttatc tgtatgcatt tgtataatta
    10381 tctgaatgaa ggcatgaagg ttaaataaag cattttgtat ggaa
//
