LOCUS       NM_013598               5472 bp    mRNA    linear   ROD 14-FEB-2024
DEFINITION  Mus musculus kit ligand (Kitl), transcript variant 1, mRNA.
ACCESSION   NM_013598
VERSION     NM_013598.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5472)
  AUTHORS   Aoki,H., Tomita,H., Hara,A. and Kunisada,T.
  TITLE     Postnatal Expression of Kitl Affects Pigmentation of the Epidermis
  JOURNAL   J Invest Dermatol 144 (1), 96-105 (2024)
   PUBMED   37482288
  REMARK    GeneRIF: Postnatal Expression of Kitl Affects Pigmentation of the
            Epidermis.
REFERENCE   2  (bases 1 to 5472)
  AUTHORS   Molfetta,R., Lecce,M., Milito,N.D., Putro,E., Pietropaolo,G.,
            Marangio,C., Scarno,G., Moretti,M., De Smaele,E., Santini,T.,
            Bernardini,G., Sciume,G., Santoni,A. and Paolini,R.
  TITLE     SCF and IL-33 regulate mouse mast cell phenotypic and functional
            plasticity supporting a pro-inflammatory microenvironment
  JOURNAL   Cell Death Dis 14 (9), 616 (2023)
   PUBMED   37730723
  REMARK    GeneRIF: SCF and IL-33 regulate mouse mast cell phenotypic and
            functional plasticity supporting a pro-inflammatory
            microenvironment.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 5472)
  AUTHORS   Hughes,C.H.K., Smith,O.E., Meinsohn,M.C., Brunelle,M., Gevry,N. and
            Murphy,B.D.
  TITLE     Steroidogenic factor 1 (SF-1; Nr5a1) regulates the formation of the
            ovarian reserve
  JOURNAL   Proc Natl Acad Sci U S A 120 (32), e2220849120 (2023)
   PUBMED   37494420
REFERENCE   4  (bases 1 to 5472)
  AUTHORS   Lee,J., Kim,Y., Ataliotis,P., Kim,H.G., Kim,D.W., Bennett,D.C.,
            Brown,N.A., Layman,L.C. and Kim,S.H.
  TITLE     Coordination of canonical and noncanonical Hedgehog signalling
            pathways mediated by WDR11 during primordial germ cell development
  JOURNAL   Sci Rep 13 (1), 12309 (2023)
   PUBMED   37516749
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 5472)
  AUTHORS   Peng,Y.J., Tang,X.T., Shu,H.S., Dong,W., Shao,H. and Zhou,B.O.
  TITLE     Sertoli cells are the source of stem cell factor for
            spermatogenesis
  JOURNAL   Development 150 (6) (2023)
   PUBMED   36861441
  REMARK    GeneRIF: Sertoli cells are the source of stem cell factor for
            spermatogenesis.
REFERENCE   6  (bases 1 to 5472)
  AUTHORS   Poole,T.W. and Silvers,W.K.
  TITLE     Capacity of adult steel (SI/SId) and dominant spotting (W/Wv) mouse
            skin to support melanogenesis
  JOURNAL   Dev Biol 72 (2), 398-400 (1979)
   PUBMED   389712
REFERENCE   7  (bases 1 to 5472)
  AUTHORS   Arfin,S.M., Hanford,W.C. and Taylor,B.A.
  TITLE     Assignment of histidase-regulating locus to chromosome 10 of the
            mouse
  JOURNAL   Biochem Genet 17 (5-6), 529-535 (1979)
   PUBMED   518536
REFERENCE   8  (bases 1 to 5472)
  AUTHORS   Kitamura,Y. and Go,S.
  TITLE     Decreased production of mast cells in S1/S1d anemic mice
  JOURNAL   Blood 53 (3), 492-497 (1979)
   PUBMED   367470
REFERENCE   9  (bases 1 to 5472)
  AUTHORS   LaVail,J.H., Nixon,R.A. and Sidman,R.L.
  TITLE     Genetic control of retinal ganglion cell projections
  JOURNAL   J Comp Neurol 182 (3), 399-421 (1978)
   PUBMED   102659
REFERENCE   10 (bases 1 to 5472)
  AUTHORS   Murphy,E.D.
  TITLE     Effects of mutant steel alleles on leukemogenesis and life-span in
            the mouse
  JOURNAL   J Natl Cancer Inst 58 (1), 107-110 (1977)
   PUBMED   319242
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC159910.6, U44725.1 and BU700928.1.
            
            [WARNING] On Mar 18, 2024 this sequence was replaced by
            NM_013598.4.
            
            On Nov 17, 2016 this sequence version replaced NM_013598.2.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: U44725.1, AK134301.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-3                 AC159910.6         106767-106769       c
            4-1859              U44725.1           1-1856
            1860-1861           AC159910.6         25770-25771         c
            1862-2382           U44725.1           1857-2377
            2383-5453           U44725.1           2379-5449
            5454-5472           BU700928.1         1-19                c
FEATURES             Location/Qualifiers
     source          1..5472
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 51.4 cM"
     gene            1..5472
                     /gene="Kitl"
                     /gene_synonym="blz; Clo; Con; contrasted; Gb; Kitlg; Mgf;
                     SCF; SF; Sl; SLF"
                     /note="kit ligand"
                     /db_xref="GeneID:17311"
                     /db_xref="MGI:MGI:96974"
     exon            1..215
                     /gene="Kitl"
                     /gene_synonym="blz; Clo; Con; contrasted; Gb; Kitlg; Mgf;
                     SCF; SF; Sl; SLF"
                     /inference="alignment:Splign:2.1.0"
     exon            216..329
                     /gene="Kitl"
                     /gene_synonym="blz; Clo; Con; contrasted; Gb; Kitlg; Mgf;
                     SCF; SF; Sl; SLF"
                     /inference="alignment:Splign:2.1.0"
     exon            330..392
                     /gene="Kitl"
                     /gene_synonym="blz; Clo; Con; contrasted; Gb; Kitlg; Mgf;
                     SCF; SF; Sl; SLF"
                     /inference="alignment:Splign:2.1.0"
     exon            393..563
                     /gene="Kitl"
                     /gene_synonym="blz; Clo; Con; contrasted; Gb; Kitlg; Mgf;
                     SCF; SF; Sl; SLF"
                     /inference="alignment:Splign:2.1.0"
     exon            564..720
                     /gene="Kitl"
                     /gene_synonym="blz; Clo; Con; contrasted; Gb; Kitlg; Mgf;
                     SCF; SF; Sl; SLF"
                     /inference="alignment:Splign:2.1.0"
     exon            721..804
                     /gene="Kitl"
                     /gene_synonym="blz; Clo; Con; contrasted; Gb; Kitlg; Mgf;
                     SCF; SF; Sl; SLF"
                     /inference="alignment:Splign:2.1.0"
     exon            805..914
                     /gene="Kitl"
                     /gene_synonym="blz; Clo; Con; contrasted; Gb; Kitlg; Mgf;
                     SCF; SF; Sl; SLF"
                     /inference="alignment:Splign:2.1.0"
     exon            915..982
                     /gene="Kitl"
                     /gene_synonym="blz; Clo; Con; contrasted; Gb; Kitlg; Mgf;
                     SCF; SF; Sl; SLF"
                     /inference="alignment:Splign:2.1.0"
     exon            983..1058
                     /gene="Kitl"
                     /gene_synonym="blz; Clo; Con; contrasted; Gb; Kitlg; Mgf;
                     SCF; SF; Sl; SLF"
                     /inference="alignment:Splign:2.1.0"
     exon            1059..5457
                     /gene="Kitl"
                     /gene_synonym="blz; Clo; Con; contrasted; Gb; Kitlg; Mgf;
                     SCF; SF; Sl; SLF"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gccggggctt catttgctgt ctgtcaccgg gaccgagagt gccgcgggaa agcaacggcc
       61 aaggacgggg cgctgcgttc gagctaccca atgctgggac tatctgcagc cgctgctggt
      121 gcaatatgct ggagctccag aacagctaaa cggagtcgcc acaccgctgc ctgggctgga
      181 tcgcagcgct gcctttcctt atgaagaaga cacaaacttg gattatcact tgcatttatc
      241 ttcaactgct cctatttaat cctcttgtca aaaccaagga gatctgcggg aatcctgtga
      301 ctgataatgt aaaagacatt acaaaactgg tggcaaatct tccaaatgac tatatgataa
      361 ccctcaacta tgtcgccggg atggatgttt tgcctagtca ttgttggcta cgagatatgg
      421 taatacaatt atcactcagc ttgactactc ttctggacaa gttctcaaat atttctgaag
      481 gcttgagtaa ttactccatc atagacaaac ttgggaaaat agtggatgac ctcgtgttat
      541 gcatggaaga aaacgcaccg aagaatataa aagaatctcc gaagaggcca gaaactagat
      601 cctttactcc tgaagaattc tttagtattt tcaatagatc cattgatgcc tttaaggact
      661 ttatggtggc atctgacact agtgactgtg tgctctcttc aacattaggt cccgagaaag
      721 attccagagt cagtgtcaca aaaccattta tgttaccccc tgttgcagcc agctccctta
      781 ggaatgacag cagtagcagt aataggaaag ccgcaaaggc ccctgaagac tcgggcctac
      841 aatggacagc catggcattg ccggctctca tttcgcttgt aattggcttt gcttttggag
      901 ccttatactg gaagaagaaa cagtcaagtc ttacaagggc agttgaaaat atacagatta
      961 atgaagagga taatgagata agtatgttgc aacagaaaga gagagaattt caagaggtgt
     1021 aattgtggac gtatcaacat tgttaccttc gcacagtggc tggtaacagt tcatgtttgc
     1081 ttcataaatg aagcagcctt aaacaaattc ccattctgtc tcaagtgaca gacctcatcc
     1141 ttacctgttc ttgctacccg tgaccttgtg tggatgattc agttgttgga gcagagtgct
     1201 tcgctgtgaa ccctgcactg aattatcatc tgtaaagaaa aatctgcacg gagcaggact
     1261 ctggaggttt tgcaagtgat gatagggaca agaacatgtg tccagtctac ttgcaccgtt
     1321 tgcatggctt gggaaacgtc tgagtgctga aaacccaccc agctttgttc ttcagtcaca
     1381 acctgcagcc tgtcgttaat tatggtctct gcaagtagat ttcagcctgg atggtggggg
     1441 gaattttttt tttcacaaag ggatgtagaa aacaatttaa aaaaacaaaa caaaacaata
     1501 actccgtagc atcagccact gtatggagtt gaaagccatg gggagtattt ttttttcttt
     1561 tgagcaggct catccgctct gtagttaatg attaaggaga gcagcctaaa tgtaagctcc
     1621 tcctgacaga agtcatggtg caccgtatcc tactagagaa atggacatgg gtagctagtt
     1681 ctatccatgc ggtggagccc atgctgaact gcagcataat accacggcat atggaagact
     1741 ctccagaaaa gtccttacag gagaaaattg tcaacgtgga ccagtggaag aacatgccaa
     1801 ggaagacatt tggcccatcg tgaagtcagt cttttccctt gacagtcact ctagcgtgtg
     1861 taaatcgtgt ttgcaatagt ataatgtgac atgcttatgt tttgaaacta ctgcagcggt
     1921 atgaagacag atatgggagg aatgctgaat gtgcaagggt ctccccaccc ccaccccccc
     1981 ttttatttta aatcctgatg ggagagaata agaacggatg atggtattta gtacctaaga
     2041 ttagaaatgg acactttatt ctaatacggg agttgcaaac taagtcactc atattctaaa
     2101 agaatgcaag gactcggaaa acattagtta tttgcagtat aaccgttatc tcttgaaaca
     2161 tagccactta tttaaatcgg gcactctgta ttcattaagg tttatgaaac gaaataaaaa
     2221 aagagagagc tttatgtagc tgtgcatgtc agtttgctat ttaaaacgtg tgacagcatt
     2281 tctcatatta gacagaaatt ggcagtgatt ccacactgag catcgcgctt tcaaaccaga
     2341 atttagagga tgtgctgtag atgtcctccc cccccccccc ccgatagaga aagcaattgg
     2401 ctagactcaa agtatgacct tttcttctgc ctttatttct ggtgaaggtt ctcttcacct
     2461 accgtagaca tacaaaactt aaagcttttc acactaactc aattcttata gtaattttat
     2521 ttgccctgtg ctaaaacctt aagacaaccc ttttcaatgt aattacacaa aagtgcacag
     2581 aaacctaact gctagcttct actctgtctt gaggctgcat gtaaagttct agcttacgtt
     2641 ccaagcttgt ccaagtacga ctccagtaca tggtggctgc tcttctttgt accaaagagt
     2701 tcagatggtc tctagttcct tctctaatgc tctgatgttc ctccaatgct atcaggtctg
     2761 caataatgaa gcccagtgca ccgagacact ggatttgctt gtgcaagccc tcagacattc
     2821 caggacacaa ctggttagta accaattaga aatcagctta gttactgaaa ggacctatac
     2881 tgttgtttgg cattgactgc tttgaaacta ataatagctg taggttaaca tgagtcatag
     2941 gtgtagctgt atatagattg agcctatcgt tccttctcag ttttgtgact tgatttattt
     3001 atctggtagt ttcattttgc ttaggcttat gaaaatacta tttactgagc tcgagagtac
     3061 aataaatata tgtttgttct caaagttagc agttggattt taatactcaa aaatgcagtc
     3121 ttaaaatcag gagagctaaa taaacaaatt taacagatta taacctctga catggtagaa
     3181 ggtggaagat gtgtcctgct tattaaacat gttggttcat tgagagtaac atagactgcc
     3241 aatttttttt agatactaag gttcaataaa atgcatgaac aataggaaaa tgctgaacat
     3301 gattttgaat gctagctgct tggatgctaa ctacggcata tctgctttca gattaaaaat
     3361 atgtatcttt gcatagctta ttccatgtat gttctgaaaa tttgtcttaa attatgaaga
     3421 ctccaagcca agaagataaa gtataaagtc accctttaaa ttgaccaatt ttttttctga
     3481 gcgttctctt ttgcaatgtg taagatttga tgttttaatg aaaatgatct gagaaatctg
     3541 cagagtataa attgtattga aagccttgta ccttcttggg agaaaccaag cctataacaa
     3601 gactatttgt gtgatcagtg ggtagcatta gtgccatcct ggtttttgta ttgttatcta
     3661 acatgtttaa cacactgcca tgtcttaatg aatcagagaa gaattgaagc tttcaaataa
     3721 gataataata ataataaaat cctaaattgt actacaaaaa gcaatgcata tgataaaaaa
     3781 atggaaacac ataaaagtat gtatgcacaa tgaagtatat gcttttagtt aagaattaaa
     3841 cacactttgg tgaactttca tgtgctttga aaaaaaataa agtcagtgct gcatagtttg
     3901 gtaatttgat tcaatcgaag ttataaatga atggaaaaat ctgttgtgta atctttgatg
     3961 gtttccacca cctctaacca taggttttaa ttttgtgatt ttaattctga taatgaaatc
     4021 ttagctattc tgtacgcatt gttgaagaaa taatgttttt caaagtaggc agttaggtgt
     4081 agttgggtga acattgagaa aggtagccag gagtttgttc tactttgcca caaacggata
     4141 taatgttccc cgctctcttt ggatctcagt gttgtgtttg tgtgtagata ggtcagagat
     4201 cagtcttcag gagtgagccc ttatgccaca caattaataa agcaaagaaa aacagcaaaa
     4261 agaatccata gcaaagtact cagctctggc ttctgaacaa taggttagac aatgagaagt
     4321 cctggctgtt ttagtttcta atgtaaatag ggtcccttag taaaagtgaa ttcagtctta
     4381 cttaggatgg attgggtaac tacacatgag atggctttta cctttgctca aacgagcgtt
     4441 tgggatcatc tttgaggaat gaaaagcggt cgtgcatttt catcaggaaa agatacaaga
     4501 tgtgtataac atttggaaat gtgtctgagg atgaatggaa atgttctcat tttattgaac
     4561 gctaagaaca acaacaaaaa agaaatgtag ggtgctacta aggatcttgg atgccaagag
     4621 atattttaaa gccaatttgt aaaaacgata acccgtaaat tctatttaaa attggaaaag
     4681 taggacaaga attttgaagt aagccagttt atctttagaa tgatattgtg aaattggctt
     4741 taaatataac cattccgatc aaatgtattt atggagtcta attacatagc cttgttactg
     4801 tcattccaca caggctaaaa acgcctctat aaggataaaa tgatagtatc tctttcctaa
     4861 ctggtgtggg cttaggagtg atccacacta aggtgactat ttatgatcct agaatgtttg
     4921 taagcattgt aaatgcacaa ctgccatctc caaatatttt cttataagac tgtttttaga
     4981 agaagaaaat tgtttaaaac aaacaaaagc tatcgtattt tcatttactc aatttctagg
     5041 ctaaaagagt tcactgaata aaattttcca atcaaaattc ctatagtctt attttccagt
     5101 agtctaggca ttcctatgtg attattgtgt ctctctacca ctgtttttta agtcaatgga
     5161 cttgagaagt attctgacat ttatatggct tcacagatat attgctagtt cagtcataga
     5221 ttggagtttg catattgtaa tgtaagtgta tgtccaacac tattctaaat agtttatgac
     5281 tgaagtttaa ttaaataaaa ggttgtaaaa tgtgatgtgt atgtgtatat actgtatgtg
     5341 tactttttaa aataggtata tgtcccgacc cttttgatac aggtttgaat ttgaaattac
     5401 attatataaa catatacttt attgttctaa ataaagaatt ttatgcacca tcataaaaaa
     5461 aaaaaaaaaa aa
//
