LOCUS       NM_177748               1734 bp    mRNA    linear   ROD 17-APR-2022
DEFINITION  Mus musculus killer cell immunoglobulin-like receptor, three
            domains, long cytoplasmic tail, 2 (Kir3dl2), mRNA.
ACCESSION   NM_177748 XM_906578
VERSION     NM_177748.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1734)
  AUTHORS   Song S, Miranda CJ, Braun L, Meyer K, Frakes AE, Ferraiuolo L,
            Likhite S, Bevan AK, Foust KD, McConnell MJ, Walker CM and Kaspar
            BK.
  TITLE     Major histocompatibility complex class I molecules protect motor
            neurons from astrocyte-induced toxicity in amyotrophic lateral
            sclerosis
  JOURNAL   Nat Med 22 (4), 397-403 (2016)
   PUBMED   26928464
  REMARK    GeneRIF: Overexpression of a single MHCI molecule, HLA-F, protects
            human MNs from ALS astrocyte-mediated toxicity, whereas knockdown
            of its receptor, the killer cell immunoglobulin-like receptor
            KIR3DL2, on human astrocytes results in enhanced MN death.
REFERENCE   2  (bases 1 to 1734)
  AUTHORS   Bryceson YT, Foster JA, Kuppusamy SP, Herkenham M and Long EO.
  TITLE     Expression of a killer cell receptor-like gene in plastic regions
            of the central nervous system
  JOURNAL   J Neuroimmunol 161 (1-2), 177-182 (2005)
   PUBMED   15748957
REFERENCE   3  (bases 1 to 1734)
  AUTHORS   Welch AY, Kasahara M and Spain LM.
  TITLE     Identification of the mouse killer immunoglobulin-like
            receptor-like (Kirl) gene family mapping to chromosome X
  JOURNAL   Immunogenetics 54 (11), 782-790 (2003)
   PUBMED   12618911
  REMARK    GeneRIF: encodes a KIR-like molecule with three Ig-like domains and
            lacks tyrosine-based immunoregulatory motifs in its cytoplasmic
            region
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AF548540.1.
            
            On or before Dec 7, 2005 this sequence version replaced
            XM_906578.1, NM_177748.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF548540.1, AF548541.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849383,
                                           SAMN00849384 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression, longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1734
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6CrSlc"
                     /db_xref="taxon:10090"
                     /chromosome="X"
                     /map="X 58.45 cM"
     gene            1..1734
                     /gene="Kir3dl2"
                     /gene_synonym="Kirl2"
                     /note="killer cell immunoglobulin-like receptor, three
                     domains, long cytoplasmic tail, 2"
                     /db_xref="GeneID:245615"
                     /db_xref="MGI:MGI:3612791"
     exon            1..39
                     /gene="Kir3dl2"
                     /gene_synonym="Kirl2"
                     /inference="alignment:Splign:2.1.0"
     exon            40..75
                     /gene="Kir3dl2"
                     /gene_synonym="Kirl2"
                     /inference="alignment:Splign:2.1.0"
     exon            76..354
                     /gene="Kir3dl2"
                     /gene_synonym="Kirl2"
                     /inference="alignment:Splign:2.1.0"
     exon            355..660
                     /gene="Kir3dl2"
                     /gene_synonym="Kirl2"
                     /inference="alignment:Splign:2.1.0"
     exon            661..957
                     /gene="Kir3dl2"
                     /gene_synonym="Kirl2"
                     /inference="alignment:Splign:2.1.0"
     exon            958..996
                     /gene="Kir3dl2"
                     /gene_synonym="Kirl2"
                     /inference="alignment:Splign:2.1.0"
     exon            997..1113
                     /gene="Kir3dl2"
                     /gene_synonym="Kirl2"
                     /inference="alignment:Splign:2.1.0"
     exon            1114..1164
                     /gene="Kir3dl2"
                     /gene_synonym="Kirl2"
                     /inference="alignment:Splign:2.1.0"
     exon            1165..1734
                     /gene="Kir3dl2"
                     /gene_synonym="Kirl2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cagccatgct gctctggttc ctcagcctca tgtgttctgg tttcttccta gtccagagga
       61 tgtcagcaca cgtgggaagt catgataaac cattcctata tgcctggcca agttatgttg
      121 ttcctctggg acagaatgtg actcttacat gtgactctca tagaggatct aacatattca
      181 aactgtacaa agaagaaggg tctccaatcc ctcagttaca tgagactaca tttcagaaga
      241 gccaggtctt tggtcctgtg accacagaac atgcaggaac ctacagatgc ttccatcctc
      301 aatatgctaa tgtattgtca gcacatagtg agcctctgaa aatcataatt tcaggaatct
      361 acttgaagcc tttcctcttg attctacaaa gtcccctggt gaattcagga gggaatgtga
      421 ccctggaatg tcactcagag aatatgttcg atacatacat tttgatttca cacagaatgg
      481 gaataatcaa gaactctgtc caagtttctg cagaacatca tgaaagtggg tcacatgtca
      541 cctactcaat aggtcccatg acacctgacc ttgttgggac ttacacatgc tatggtgcta
      601 acagttacta cccctatgaa tggtcagacc ccagtgaccc cattgacatc aagatcacag
      661 gtgtatacaa gaaaccttct ctgtcagtcc tgatggggcc tgtgctgatg atgtcaggag
      721 aaaccatgac cctgtcttgc atctctgacc atcagtttga catgttccat atgtccaggg
      781 aaggggtgcc tcagggacag gggatgcctg gagtgcagat ccacagtggt aaattcgagg
      841 caaaattcct tcttagttca atgatccaaa aggggaacta tagatgctat ggctctttca
      901 ggaactcttc ccatgtgtgg tcctccccaa gtgacccctt gtaccttcct gccaaaggaa
      961 actgtcctgc atgcacagaa gaagatccca aaatacataa ctgcaagaac ctgcgcattc
     1021 taactgggct cttaatgacc atggtccttg tcatcatcat catcttttat tcttgttact
     1081 ttcccaaaca gaataagtct cagaaacaag cagcagccag catggaacaa gagtctgaag
     1141 ttaaaaaaca caataaacag acagctttct aggactttga aggacaagaa ggacaggagg
     1201 tgacatacac agaacttgag cagagaatct tcaaccaaaa cttgatgcct cccatttccc
     1261 gaatttctga gttttctgca gataccattg tgtacatgga aattatgaaa tgataaactg
     1321 agatcaaaga atgtctgcac ccactgagtt ctcaaagaaa gatctaagga agtcttttgt
     1381 ggaaaacaga gccttttcat caacaaaggc tgtttgatgc agtgaaataa cagctggaat
     1441 atgaaggcag aagtctttaa atttggggtt atccttaatt gttctaatac tgttcttaat
     1501 gtagtttact aatacataaa aagactatgg tcctcactga cagcattaca gaaatcacat
     1561 tctatttatt agtccatggt tctccacgta ttccctagtt tcagacctct acaatgtaac
     1621 caactatatt tttagatcga cttgaagctg catgctgttt gtcttacaat tccataccaa
     1681 caaaggttca ttctgcttat tagcatagat ttccaatata ttgttatgct gtac
//
