LOCUS       NM_001416297            3483 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus kinesin family member C2 (Kifc2), transcript variant
            8, mRNA.
ACCESSION   NM_001416297
VERSION     NM_001416297.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3483)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3483)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   3  (bases 1 to 3483)
  AUTHORS   Tang,F., Barbacioru,C., Nordman,E., Bao,S., Lee,C., Wang,X.,
            Tuch,B.B., Heard,E., Lao,K. and Surani,M.A.
  TITLE     Deterministic and stochastic allele specific gene expression in
            single mouse blastomeres
  JOURNAL   PLoS One 6 (6), e21208 (2011)
   PUBMED   21731673
REFERENCE   4  (bases 1 to 3483)
  AUTHORS   Nath,S., Bananis,E., Sarkar,S., Stockert,R.J., Sperry,A.O.,
            Murray,J.W. and Wolkoff,A.W.
  TITLE     Kif5B and Kifc1 interact and are required for motility and fission
            of early endocytic vesicles in mouse liver
  JOURNAL   Mol Biol Cell 18 (5), 1839-1849 (2007)
   PUBMED   17360972
REFERENCE   5  (bases 1 to 3483)
  AUTHORS   Piao,Y., Ko,N.T., Lim,M.K. and Ko,M.S.
  TITLE     Construction of long-transcript enriched cDNA libraries from
            submicrogram amounts of total RNAs by a universal PCR amplification
            method
  JOURNAL   Genome Res 11 (9), 1553-1558 (2001)
   PUBMED   11544199
REFERENCE   6  (bases 1 to 3483)
  AUTHORS   Venables,J.P., Vernet,C., Chew,S.L., Elliott,D.J., Cowmeadow,R.B.,
            Wu,J., Cooke,H.J., Artzt,K. and Eperon,I.C.
  TITLE     T-STAR/ETOILE: a novel relative of SAM68 that interacts with an
            RNA-binding protein implicated in spermatogenesis
  JOURNAL   Hum Mol Genet 8 (6), 959-969 (1999)
   PUBMED   10332027
REFERENCE   7  (bases 1 to 3483)
  AUTHORS   Yang,Z., Hanlon,D.W., Marszalek,J.R. and Goldstein,L.S.
  TITLE     Identification, partial characterization, and genetic mapping of
            kinesin-like protein genes in mouse
  JOURNAL   Genomics 45 (1), 123-131 (1997)
   PUBMED   9339368
REFERENCE   8  (bases 1 to 3483)
  AUTHORS   Nakagawa,T., Tanaka,Y., Matsuoka,E., Kondo,S., Okada,Y., Noda,Y.,
            Kanai,Y. and Hirokawa,N.
  TITLE     Identification and classification of 16 new kinesin superfamily
            (KIF) proteins in mouse genome
  JOURNAL   Proc Natl Acad Sci U S A 94 (18), 9654-9659 (1997)
   PUBMED   9275178
  REMARK    Erratum:[Proc Natl Acad Sci U S A 1999 Mar 30;96(7):4214]
REFERENCE   9  (bases 1 to 3483)
  AUTHORS   Hanlon,D.W., Yang,Z. and Goldstein,L.S.
  TITLE     Characterization of KIFC2, a neuronal kinesin superfamily member in
            mouse
  JOURNAL   Neuron 18 (3), 439-451 (1997)
   PUBMED   9115737
REFERENCE   10 (bases 1 to 3483)
  AUTHORS   Saito,N., Okada,Y., Noda,Y., Kinoshita,Y., Kondo,S. and Hirokawa,N.
  TITLE     KIFC2 is a novel neuron-specific C-terminal type kinesin
            superfamily motor for dendritic transport of multivesicular
            body-like organelles
  JOURNAL   Neuron 18 (3), 425-438 (1997)
   PUBMED   9115736
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC156550.5.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660817.87534.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164132
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-426               AC156550.5         37440-37865
            427-508             AC156550.5         38106-38187
            509-657             AC156550.5         38336-38484
            658-796             AC156550.5         38580-38718
            797-942             AC156550.5         38827-38972
            943-1008            AC156550.5         39046-39111
            1009-1137           AC156550.5         39201-39329
            1138-1215           AC156550.5         39695-39772
            1216-1330           AC156550.5         39882-39996
            1331-1440           AC156550.5         40074-40183
            1441-1549           AC156550.5         41171-41279
            1550-1752           AC156550.5         41343-41545
            1753-1857           AC156550.5         43129-43233
            1858-1979           AC156550.5         43329-43450
            1980-2103           AC156550.5         43547-43670
            2104-2233           AC156550.5         43763-43892
            2234-2490           AC156550.5         43975-44231
            2491-3483           AC156550.5         44304-45296
FEATURES             Location/Qualifiers
     source          1..3483
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="15"
                     /map="15 36.23 cM"
     gene            1..3483
                     /gene="Kifc2"
                     /note="kinesin family member C2"
                     /db_xref="GeneID:16581"
                     /db_xref="MGI:MGI:109187"
     exon            1..426
                     /gene="Kifc2"
                     /inference="alignment:Splign:2.1.0"
     CDS             328..2745
                     /gene="Kifc2"
                     /note="isoform 11 is encoded by transcript variant 8;
                     kinesin-like protein KIFC2"
                     /codon_start=1
                     /product="kinesin-like protein KIFC2 isoform 11"
                     /protein_id="NP_001403226.1"
                     /db_xref="GeneID:16581"
                     /db_xref="MGI:MGI:109187"
                     /translation="MYAFYSLLIYIFYSLFRRDGGAAAVSDPGDPTQKSGGQPRGRRR
                     PDQFTSELWSELNSLAGCSESEDGQKGAEGGAAEVSLEEALMRLAEFLSVQLGAEESC
                     GTTPDLGKPGEVPPLLTVTSQLLALLAWTRSPRGRQALLQGTQPTCPVQPSTLDGSLS
                     QEESSSQPTPILDEVPRDETQEHQPLQLEEEQRVWQRLEQLILGQLEELRQQLEQQEE
                     ELSRLRLGVGVTDSEKRVQHLTLENEALKQSLSLTRDLLLHWGPGPLPRLSQEEAGAL
                     LELQGQLQEAQDTTEALRVQLGAQELQLQGLQGALRQLQQETEQNCRQELQQVHGQLA
                     GLRARMASLRQGCGDLRGLVSTFTQSCQGSLSEAQGQVSWALGALSAGKAKTQLSEGN
                     QAPPTGCSGRLLELKGLWRQYADVVPNAGNIRVLCRLRPAEGQPSSLVSVEPGQGGTI
                     TTCYRGRQHRFRLDWVFPQDASQEEVFRQLEPAVLSCLQGYSVCIFTYGQTGTGKTYS
                     MEGPPEDPGIAPRALQLLFREMGTGGHHHVTLSMVEIYNEAVRDLLATGPPERLVVRQ
                     GPAGQGGIQVAGLTHWDVPNLETLHQMLSLGRSNRATAATVMNQHSSRSHALVTLTLR
                     AASPPRAQGITGTLHLVDLAGSERVWKAGVASPVQRDPNGARRLREAQAINRSLLALG
                     GVMAALRARRPHVPFRDSQLTRLLQPALCAGTTAVLLLQISTRAEDLGETICSLKFAE
                     RVGQVELGPARRRRAPRSGTPSSLSTDTPLTGTSCTPTPSPGSPPSTSPNSCSGLTLE
                     PPGDPPP"
     exon            427..508
                     /gene="Kifc2"
                     /inference="alignment:Splign:2.1.0"
     exon            509..657
                     /gene="Kifc2"
                     /inference="alignment:Splign:2.1.0"
     exon            658..796
                     /gene="Kifc2"
                     /inference="alignment:Splign:2.1.0"
     exon            797..942
                     /gene="Kifc2"
                     /inference="alignment:Splign:2.1.0"
     exon            943..1008
                     /gene="Kifc2"
                     /inference="alignment:Splign:2.1.0"
     exon            1009..1137
                     /gene="Kifc2"
                     /inference="alignment:Splign:2.1.0"
     exon            1138..1215
                     /gene="Kifc2"
                     /inference="alignment:Splign:2.1.0"
     exon            1216..1330
                     /gene="Kifc2"
                     /inference="alignment:Splign:2.1.0"
     exon            1331..1440
                     /gene="Kifc2"
                     /inference="alignment:Splign:2.1.0"
     exon            1441..1549
                     /gene="Kifc2"
                     /inference="alignment:Splign:2.1.0"
     exon            1550..1752
                     /gene="Kifc2"
                     /inference="alignment:Splign:2.1.0"
     exon            1753..1857
                     /gene="Kifc2"
                     /inference="alignment:Splign:2.1.0"
     exon            1858..1979
                     /gene="Kifc2"
                     /inference="alignment:Splign:2.1.0"
     exon            1980..2103
                     /gene="Kifc2"
                     /inference="alignment:Splign:2.1.0"
     exon            2104..2233
                     /gene="Kifc2"
                     /inference="alignment:Splign:2.1.0"
     exon            2234..2490
                     /gene="Kifc2"
                     /inference="alignment:Splign:2.1.0"
     exon            2491..3483
                     /gene="Kifc2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3460..3465
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Kifc2"
                     /note="hexamer: ATTAAA"
     polyA_site      3483
                     /gene="Kifc2"
                     /note="major polyA site"
ORIGIN      
        1 agaagaggtt gtacacctga gagctgaagg ctcggttccc ttgcgcgttt cttggtgggg
       61 gtcttgatgc gggattccca aaagagacta gacagcggct agaggtcttt gcgaaagagg
      121 gactaaaaac cgcttgatag ggccttaagt acaagttttg cagctcttcg cagtcgcccc
      181 tcagtgaggg ccctccgccc gtggaagatc gtccgtgggg gcgaccgccg cgagcatgcg
      241 catgggcact gcggcgggcg ggtgcagaga cctggtgcgg ggacgcgggg cggcgcgaag
      301 aggtgctctc tgccgccccg cgcccccatg tacgcctttt actctctgct catctacatc
      361 ttctacagtc ttttccgcag ggatggcggg gctgcggcgg tctcggaccc cggggatccc
      421 acccagaaaa gcggcggcca acctaggggt cgtcgccgtc cggatcaatt cacatcagaa
      481 ctgtggtccg agctgaacag cctggccggc tgctcagaat ctgaggatgg ccagaaagga
      541 gcggagggtg gagcagctga ggtgtccctg gaagaggcac tcatgcgtct tgctgagttc
      601 ctctccgtcc agttgggggc agaagagagc tgcgggacga ctcctgacct gggcaagcct
      661 ggtgaagtcc ccccactgtt gacagtaaca agtcagctct tggccctact ggcatggaca
      721 cggagccccc gggggaggca ggccctgctc caggggactc agccaacctg ccccgtgcag
      781 ccctccactc tagatgggtc tctttcacaa gaagaaagct cctctcagcc cactcccatc
      841 ctggatgagg taccaaggga tgagacccag gaacatcagc ctctccaatt ggaggaggaa
      901 cagagagttt ggcagcggtt ggaacagctc attcttggac agctggaaga gctgagacaa
      961 cagctggagc aacaggaaga agagctgagt agacttcgtc tgggagtggg ggtgacagat
     1021 tcagagaaga gagtccagca cctcacattg gagaacgaag ccttgaaaca gagcttgagc
     1081 cttactcggg acctcctgct acactggggg cctggaccac tccccagact ttcccaggag
     1141 gaggcagggg cactgttgga gctgcagggc cagcttcaag aggcccagga caccacagaa
     1201 gctctccgag tccagctggg ggcccaggag ctgcagctgc agggccttca aggggccctc
     1261 cggcagctcc agcaggagac agagcagaac tgcagacagg agctgcagca agttcacgga
     1321 cagctggcag gactacgggc acggatggcc agccttcgtc agggatgtgg ggacctccga
     1381 ggactggtca gcacctttac gcagagttgc cagggctcgc tgagtgaggc tcagggccag
     1441 gtttcctggg cccttggggc tctgtcagct ggaaaggcta agactcaact ctcagaaggg
     1501 aaccaagcac ccccaactgg atgctcaggg cggcttttgg aactcaaggg gctatggagg
     1561 caatatgccg atgtggtccc caatgcaggg aatattcgtg tcctgtgtcg gctgagacca
     1621 gctgaagggc agccttccag cctggtgagc gtggagcctg gacaaggggg aaccatcacc
     1681 acatgttacc gaggacgcca gcatcgcttt cgcctggact gggtctttcc tcaagatgcc
     1741 agccaggagg aggtcttcag gcagctggag ccagctgtgt tgtcctgcct ccaggggtac
     1801 agtgtctgca tcttcactta tggtcagact gggacaggga aaacctacag catggagggc
     1861 ccacctgagg accctggcat agctcctagg gcactgcagt tgctgttccg ggagatgggg
     1921 actggagggc accaccatgt gaccctcagt atggtggaga tctacaacga ggcagtcagg
     1981 gacctcctag ctacagggcc tccagagcgc ctggtagtaa ggcagggacc tgcagggcag
     2041 gggggaattc aagtggctgg cctcacacac tgggacgtac ctaacctgga aaccctgcac
     2101 cagatgctga gtctggggag aagcaaccga gctacagcag ccactgtcat gaaccagcac
     2161 agctcacgct cccacgccct agttacgctg actttacgtg cagcgtctcc gcctcgggcc
     2221 cagggtatca caggcacact gcacctggtg gacctggcag ggtctgaacg ggtgtggaaa
     2281 gcaggggtgg ccagcccggt ccagagagac ccgaatggcg cccggcgtct gcgtgaggcc
     2341 caggcaatca accgctcctt gctggcacta ggaggagtga tggcggcgct gcgagctcgg
     2401 aggcctcatg tgcccttccg cgactcacag cttacgcgcc tgttacagcc ggcgctctgc
     2461 gcaggcacca ctgcagttct gctgctgcag atctccacaa gggcggaaga tctcggggag
     2521 accatctgct cgctcaagtt cgccgagcga gtgggtcaag tggaactggg gcccgcccgg
     2581 cgccgtagag ccccacgctc tggaacccct tcttctctca gtactgacac cccactcact
     2641 ggaacttcct gcacccctac accatctccc ggaagccctc ccagtaccag ccctaacagc
     2701 tgttctggct tgactcttga acctccaggg gacccgcctc cctagatctg ggtcaacgcc
     2761 cctggtactg ggcttgagaa tgtacctctg ctggcagagg cagctgtgaa tcctataccc
     2821 cacttcccag gtcaaccttt aaaaaacaaa aactctgggg ccctaactgc ccccaacaga
     2881 gccctacagt gtcccccttc ctcttctaga tctggccaga gaatgttatg ctttgagaaa
     2941 ggatcgcctc cacccttcca cccccagctg agccacaggc ccttagttct ccccccttcc
     3001 ttatcgccat ttgcccttat cacagcacac agcagggggc cagagctgca ggaaccagac
     3061 cccagaccaa gtggtttccc aagtcgccac cctgccccca ataccagact tggaattaaa
     3121 atgttgtaaa ttcctttact attaatcgct cccctacttc cattacacca aaattatgtc
     3181 cgttccagtc tttcatttct taaccctttc cctgaaaggt gctaccctct acccaggcat
     3241 ttgagagagg gcaagacttc agatcggacc cacttttggc tctccctccc cccagcctgg
     3301 agccaggaag gcatggtgac agagggatgg atagatggat ggcttgaggg cctgaaaagg
     3361 taggatcaag aggaggcact ctacaggctg agctccgctc ctggcacgat tggccagacc
     3421 tccctatcta gcagagacaa ccctttctgg agtaacctaa ttaaagctgt gggttttcag
     3481 caa
//
