LOCUS       NM_028197               2535 bp    mRNA    linear   ROD 31-JUL-2024
DEFINITION  Mus musculus kinesin family binding protein (Kifbp), mRNA.
ACCESSION   NM_028197
VERSION     NM_028197.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2535)
  AUTHORS   Martinez-Mayer,J., Brinkmeier,M.L., O'Connell,S.P., Ukagwu,A.,
            Marti,M.A., Miras,M., Forclaz,M.V., Benzrihen,M.G., Cheung,L.Y.M.,
            Camper,S.A., Ellsworth,B.S., Raetzman,L.T., Perez-Millan,M.I. and
            Davis,S.W.
  TITLE     Knockout mice with pituitary malformations help identify human
            cases of hypopituitarism
  JOURNAL   Genome Med 16 (1), 75 (2024)
   PUBMED   38822427
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2535)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 2535)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 2535)
  AUTHORS   Chang,H.Y., Cheng,H.Y., Tsao,A.N., Liu,C. and Tsai,J.W.
  TITLE     Multiple Functions of KBP in Neural Development Underlie Brain
            Anomalies in Goldberg-Shprintzen Syndrome
  JOURNAL   Front Mol Neurosci 12, 265 (2019)
   PUBMED   31736709
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 2535)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 2535)
  AUTHORS   Lehti,M.S., Kotaja,N. and Sironen,A.
  TITLE     KIF1-binding protein interacts with KIF3A in haploid male germ
            cells
  JOURNAL   Reproduction 150 (3), 209-216 (2015)
   PUBMED   26245936
  REMARK    GeneRIF: KIF1-binding protein interacts with KIF3A in haploid male
            germ cells, promoting spermatid elongation.
REFERENCE   7  (bases 1 to 2535)
  AUTHORS   Alves,M.M., Burzynski,G., Delalande,J.M., Osinga,J., van der
            Goot,A., Dolga,A.M., de Graaff,E., Brooks,A.S., Metzger,M.,
            Eisel,U.L., Shepherd,I., Eggen,B.J. and Hofstra,R.M.
  TITLE     KBP interacts with SCG10, linking Goldberg-Shprintzen syndrome to
            microtubule dynamics and neuronal differentiation
  JOURNAL   Hum Mol Genet 19 (18), 3642-3651 (2010)
   PUBMED   20621975
  REMARK    GeneRIF: KBP expression is up-regulated during neuronal development
            in mouse cortical neurons.
REFERENCE   8  (bases 1 to 2535)
  AUTHORS   Wozniak,M.J., Melzer,M., Dorner,C., Haring,H.U. and Lammers,R.
  TITLE     The novel protein KBP regulates mitochondria localization by
            interaction with a kinesin-like protein
  JOURNAL   BMC Cell Biol 6, 35 (2005)
   PUBMED   16225668
  REMARK    GeneRIF: KBP is a new binding partner for KIF1Balpha that is a
            regulator of its transport function and thus represents a new type
            of kinesin interacting protein.
            Publication Status: Online-Only
REFERENCE   9  (bases 1 to 2535)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Koseki,H., Hiraoka,S.,
            Saga,Y., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: III. the complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (4), 167-180 (2003)
   PUBMED   14621295
REFERENCE   10 (bases 1 to 2535)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY729088.1, BC055307.1 and BC038828.1.
            
            On Aug 12, 2005 this sequence version replaced NM_028197.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC055307.1, AK141324.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            RefSeq Select criteria             :: based on conservation,
                                                  expression, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-46                BY729088.1         2-47
            47-1613             BC055307.1         1-1567
            1614-2399           BC038828.1         923-1708
            2400-2535           BC055307.1         2354-2489
FEATURES             Location/Qualifiers
     source          1..2535
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 32.43 cM"
     gene            1..2535
                     /gene="Kifbp"
                     /gene_synonym="0710007C18Rik; 2510003E04Rik; KBP; Kif1bp;
                     mKIAA1279"
                     /note="kinesin family binding protein"
                     /db_xref="GeneID:72320"
                     /db_xref="MGI:MGI:1919570"
     exon            1..494
                     /gene="Kifbp"
                     /gene_synonym="0710007C18Rik; 2510003E04Rik; KBP; Kif1bp;
                     mKIAA1279"
                     /inference="alignment:Splign:2.1.0"
     exon            495..593
                     /gene="Kifbp"
                     /gene_synonym="0710007C18Rik; 2510003E04Rik; KBP; Kif1bp;
                     mKIAA1279"
                     /inference="alignment:Splign:2.1.0"
     exon            594..673
                     /gene="Kifbp"
                     /gene_synonym="0710007C18Rik; 2510003E04Rik; KBP; Kif1bp;
                     mKIAA1279"
                     /inference="alignment:Splign:2.1.0"
     exon            674..857
                     /gene="Kifbp"
                     /gene_synonym="0710007C18Rik; 2510003E04Rik; KBP; Kif1bp;
                     mKIAA1279"
                     /inference="alignment:Splign:2.1.0"
     exon            858..942
                     /gene="Kifbp"
                     /gene_synonym="0710007C18Rik; 2510003E04Rik; KBP; Kif1bp;
                     mKIAA1279"
                     /inference="alignment:Splign:2.1.0"
     exon            943..1058
                     /gene="Kifbp"
                     /gene_synonym="0710007C18Rik; 2510003E04Rik; KBP; Kif1bp;
                     mKIAA1279"
                     /inference="alignment:Splign:2.1.0"
     exon            1059..2472
                     /gene="Kifbp"
                     /gene_synonym="0710007C18Rik; 2510003E04Rik; KBP; Kif1bp;
                     mKIAA1279"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2446..2451
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Kifbp"
                     /gene_synonym="0710007C18Rik; 2510003E04Rik; KBP; Kif1bp;
                     mKIAA1279"
                     /note="hexamer: AATAAA"
     polyA_site      2472
                     /gene="Kifbp"
                     /gene_synonym="0710007C18Rik; 2510003E04Rik; KBP; Kif1bp;
                     mKIAA1279"
                     /note="major polyA site"
ORIGIN      
        1 gtaaatgaag tgtcgcaacg cggaggcctc cagtggctgc tggtccacgg acggggaggc
       61 ggccgtcagc tcaggccgcg atggcgaacg ctccggggcc agagatccgc gagaagttcc
      121 aggcagcgct ggccctgtcg cgggtggagc tgcacaagaa cccggagaag gagccgtaca
      181 agtccaagta cggcgcgcgc gcgctgttgg aggaggtgcg cgcgctgctg ggcccggcgc
      241 ccgaggacga ggacgagccg gctgctgacg atgggccggg cgaccaggcc ttgggcgcgg
      301 gtgagccccg ggaggctgag ggccccggag cgcagcgggc gctgcgcctc gcggtggtcg
      361 agttccacct tggtgtgaac cacatcgaca cggaggaact gtctgccggc gaggagcatc
      421 tggtcaggtg cctgtcgttg ctgcgcccct accgcctgtc gctcggctgt gtgtctctct
      481 acatccaggc gcagaataac ctgggcatcc tgtggtctga aagggaagag atcgaaaccg
      541 cccggaccta cctggagtca tcggaagccc tgtacagtca gtacatgaaa gagattggga
      601 gcccgcctct tgacccgact gagcattttc ttcctgaaga agagaaactt actgaacaag
      661 agagatcaaa aagatttgag aaggtttata ctcataacct gtattacctg gctcaagtct
      721 accagcacat ggaaatgttc gagaaggccg ctcattattg ccacagcaca ctgaaacgcc
      781 agcttgaaca caatgcctac caccccatgg agtgggccat caacgccgct actctatcac
      841 agttctacat caataagctc tgttttatgg aagccagaca ttgtctgtca gctgctaatg
      901 ttatttttgg tcaaactgga aaaataccag ctacagaaga cactcctgaa gttgaaggag
      961 acgtgccaga gctttaccat cagaggaaag gggaaatagc aagatgctgg atcaagtact
     1021 gcctgactct gatgcaaaac gcgcagctct ccatgcagga caacatagga gagcttgacc
     1081 tggacaagca gtcggagctc agagctctac gcaagaagga gctagatgag gaggagagcg
     1141 tcaggaaaag ggctgtgcag tttggaactg gggagctgtg cgacgccatc tctgcagtgg
     1201 aggagaaagt gagatacttg aggcccttag attttgaaga agccagggag cttttcctgc
     1261 tgggtcagca ctatgtgtgt gaggcaaagg agttcttcca gatcgatggg tatgtcactg
     1321 accacattga agttgtccag gaccacagcg ctctgttcaa ggtgctctcg ttctttgagg
     1381 ctgacatgga gagacggtgc aagatgcaca agcgcaggat agccatgcta gagcccctga
     1441 ctgtggacct gaacccacag tactacctgt tggtcagcag gcagattcag tttgaaatcg
     1501 cacacgcgta ctatgacatg atggacttga aggtcgccat tgctgacaag ctcagggacc
     1561 ccgactcaca cattgtcaaa aaaataaata gcctgaataa gtcggcactc aagtactacc
     1621 agctcttcct agactccctg agagacccaa acaaagtctt tcctgagcac atcggggaag
     1681 acgtcctccg cccggccatg ttagctaaat tccgggtagc tcgtctgtat ggcaaaatca
     1741 tcactgcaga tcccaagaaa gagctagaga atttggcaac atctttggaa cattacaaat
     1801 ttattgttga ttactgtgaa actcaccccg aggctgccca ggaaatagag gttgagttag
     1861 aacttagtaa agagatggtc agtctcctcc caacaaaaat ggagaggttc agagccaaga
     1921 tggccctgac ctaagccttg gtcaaaggaa agagacgtgc agcttgaagc cactcccctc
     1981 ccctatagca aatgaggccc agccccacag tcaccttcgc cagggccaga gggatgcact
     2041 ctgggctcca gaagcaggca ggtacccgag tctatgctag gaccttaagc accataaatt
     2101 aataatttat acctaattat gtaagttgcc ttgctaaagt gacaggtgtt ttgcattttc
     2161 gatcgcttgt tttcctgttt aagtataaac atctcctgcc tagagttcta aatgttaagt
     2221 ccttgctgac agtacttgtt agatttcata ctaggaacaa cactgggtag tgtacctggt
     2281 agaagagcct gttgctgtgt tgaatgtgag aaagtcactt cagatgtcat tctttgtaaa
     2341 atacttactt tcttaaactc caaataaatc tttccctttt gaaaatacta aaaacttaat
     2401 aatgttgtaa aatggcttaa ttataggact gaagaacttg cacataataa atttacttgt
     2461 ttcaactagt aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
     2521 aaaaaaaaaa aaaaa
//
