LOCUS       NM_001411179            3379 bp    mRNA    linear   ROD 14-OCT-2024
DEFINITION  Mus musculus kinesin family member 9 (Kif9), transcript variant 5,
            mRNA.
ACCESSION   NM_001411179 XM_006511943
VERSION     NM_001411179.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3379)
  AUTHORS   Fang,C., Pan,X., Li,D., Chen,W., Huang,Y., Chen,Y., Li,L., Gao,Q.,
            Liang,X., Li,D., Zhu,X. and Yan,X.
  TITLE     Distinct roles of Kif6 and Kif9 in mammalian ciliary trafficking
            and motility
  JOURNAL   J Cell Biol 223 (11) (2024)
   PUBMED   39158699
  REMARK    GeneRIF: Distinct roles of Kif6 and Kif9 in mammalian ciliary
            trafficking and motility.
REFERENCE   2  (bases 1 to 3379)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 3379)
  AUTHORS   Miyata,H., Oyama,Y., Kaneda,Y. and Ikawa,M.
  TITLE     The motor domain of testis-enriched kinesin KIF9 is essential for
            its localization in the mouse flagellum
  JOURNAL   Exp Anim 71 (1), 46-52 (2022)
   PUBMED   34526446
  REMARK    GeneRIF: The motor domain of testis-enriched kinesin KIF9 is
            essential for its localization in the mouse flagellum.
REFERENCE   4  (bases 1 to 3379)
  AUTHORS   Miyata,H., Morohoshi,A. and Ikawa,M.
  TITLE     Analysis of the sperm flagellar axoneme using gene-modified mice
  JOURNAL   Exp Anim 69 (4), 374-381 (2020)
   PUBMED   32554934
  REMARK    Review article
REFERENCE   5  (bases 1 to 3379)
  AUTHORS   Miyata,H., Shimada,K., Morohoshi,A., Oura,S., Matsumura,T., Xu,Z.,
            Oyama,Y. and Ikawa,M.
  TITLE     Testis-enriched kinesin KIF9 is important for progressive motility
            in mouse spermatozoa
  JOURNAL   FASEB J 34 (4), 5389-5400 (2020)
   PUBMED   32072696
REFERENCE   6  (bases 1 to 3379)
  AUTHORS   Yoon,H., Lee,D.J., Kim,M.H. and Bok,J.
  TITLE     Identification of genes concordantly expressed with Atoh1 during
            inner ear development
  JOURNAL   Anat Cell Biol 44 (1), 69-78 (2011)
   PUBMED   21519551
REFERENCE   7  (bases 1 to 3379)
  AUTHORS   Takano,K., Miki,T., Katahira,J. and Yoneda,Y.
  TITLE     NXF2 is involved in cytoplasmic mRNA dynamics through interactions
            with motor proteins
  JOURNAL   Nucleic Acids Res 35 (8), 2513-2521 (2007)
   PUBMED   17403691
REFERENCE   8  (bases 1 to 3379)
  AUTHORS   Piddini,E., Schmid,J.A., de Martin,R. and Dotti,C.G.
  TITLE     The Ras-like GTPase Gem is involved in cell shape remodelling and
            interacts with the novel kinesin-like protein KIF9
  JOURNAL   EMBO J 20 (15), 4076-4087 (2001)
   PUBMED   11483511
REFERENCE   9  (bases 1 to 3379)
  AUTHORS   Nakagawa,T., Tanaka,Y., Matsuoka,E., Kondo,S., Okada,Y., Noda,Y.,
            Kanai,Y. and Hirokawa,N.
  TITLE     Identification and classification of 16 new kinesin superfamily
            (KIF) proteins in mouse genome
  JOURNAL   Proc Natl Acad Sci U S A 94 (18), 9654-9659 (1997)
   PUBMED   9275178
  REMARK    Erratum:[Proc Natl Acad Sci U S A 1999 Mar 30;96(7):4214]
REFERENCE   10 (bases 1 to 3379)
  AUTHORS   Winter,H., Siry,P., Tobiasch,E. and Schweizer,J.
  TITLE     Sequence and expression of murine type I hair keratins mHa2 and
            mHa3
  JOURNAL   Exp Cell Res 212 (2), 190-200 (1994)
   PUBMED   7514534
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC132103.3.
            
            On Aug 23, 2022 this sequence version replaced XM_006511943.5.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR17784649.643755.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384, SAMN01164131
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-90                AC132103.3         169367-169456       c
            91-336              AC132103.3         168209-168454       c
            337-434             AC132103.3         163292-163389       c
            435-600             AC132103.3         161250-161415       c
            601-707             AC132103.3         157808-157914       c
            708-932             AC132103.3         156390-156614       c
            933-1016            AC132103.3         151965-152048       c
            1017-1109           AC132103.3         151766-151858       c
            1110-1257           AC132103.3         150492-150639       c
            1258-1322           AC132103.3         149469-149533       c
            1323-1400           AC132103.3         144784-144861       c
            1401-1469           AC132103.3         140189-140257       c
            1470-1574           AC132103.3         139685-139789       c
            1575-1630           AC132103.3         136937-136992       c
            1631-1721           AC132103.3         135979-136069       c
            1722-1855           AC132103.3         134996-135129       c
            1856-2050           AC132103.3         131827-132021       c
            2051-2265           AC132103.3         128731-128945       c
            2266-2442           AC132103.3         127239-127415       c
            2443-2558           AC132103.3         126835-126950       c
            2559-2663           AC132103.3         125086-125190       c
            2664-3379           AC132103.3         122008-122723       c
FEATURES             Location/Qualifiers
     source          1..3379
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 59.92 cM"
     gene            1..3379
                     /gene="Kif9"
                     /note="kinesin family member 9"
                     /db_xref="GeneID:16578"
                     /db_xref="MGI:MGI:1098237"
     exon            1..90
                     /gene="Kif9"
                     /inference="alignment:Splign:2.1.0"
     exon            91..336
                     /gene="Kif9"
                     /inference="alignment:Splign:2.1.0"
     CDS             300..2774
                     /gene="Kif9"
                     /note="isoform 3 is encoded by transcript variant 5;
                     kinesin-like protein KIF9; kinesin 9"
                     /codon_start=1
                     /product="kinesin-like protein KIF9 isoform 3"
                     /protein_id="NP_001398108.1"
                     /db_xref="GeneID:16578"
                     /db_xref="MGI:MGI:1098237"
                     /translation="MKRHKNGSKQYLTKMGTRKKVQAFVRVRPTDDFAHEMIKYGEDN
                     KSIDIHLKKDTRRGVVNNQQTDWSFKLDGVLHNASQDLVYETVAKDAVSQALDGYNGT
                     IMCYGQTGAGKTYTMTGATENYKHRGILPRALQQVFRMIEERPTHAITVRVSYLEIYN
                     ENLFDLLSTLPYVGPSVTPMTIVENPQGIFIKGLSVHLTSQEEDAFSLLFEGETNRII
                     ASHTMNKNSSRSHCIFTIYMEAHSRTLSDEKYITSKINLVDLAGSERLSKTGSEGRVL
                     KEATYINKSLSFLEQAIIALGDQNRDHVPFRQSKLTHALKDSLGGNCNMVLVTNIYGE
                     AAQLDETLSSLRFASRMKLVTTEPAINEKYDAERMVKNLEKELALLKQELAIHDSLSN
                     RTLVNYDPMDEIQIAEINSQVRRYLEGTLDEIDIINLRQIQEVFNQFRVVLSQQEQEV
                     ESALRRKYTLIDKNDFAAISAVQKVGLMDIEGNLVGEPDGQSFGLGVAPFSVKPGKKP
                     KTKKTPKDQFSSSARKEGASSPVSGKDFDVASISKTQLIPSSKDGDLKDMLARERETS
                     SIEPLISDSPKEELRAPRPSTPPSRTVAFEEFKNERGSEINRIFKENKSILNERKKRA
                     SETTQRINAIKQEIDETKDALNFQKSLREKQGEYENKGLMIIDEEEFLLILKLKDLKK
                     QYRNEYQELRDLRAEIQYCQRLVDQCRHRLLMEFDIWYNESFMIPEDVQVALKLGSSI
                     RPGMVPISRIVCLGEDDQDRFSHLQQTVLPEGLDSITFYNAKVKTDQKAYGSIRRAWW
                     RAACIINALNLRRTGVDQGYDKPIRP"
     exon            337..434
                     /gene="Kif9"
                     /inference="alignment:Splign:2.1.0"
     exon            435..600
                     /gene="Kif9"
                     /inference="alignment:Splign:2.1.0"
     exon            601..707
                     /gene="Kif9"
                     /inference="alignment:Splign:2.1.0"
     exon            708..932
                     /gene="Kif9"
                     /inference="alignment:Splign:2.1.0"
     exon            933..1016
                     /gene="Kif9"
                     /inference="alignment:Splign:2.1.0"
     exon            1017..1109
                     /gene="Kif9"
                     /inference="alignment:Splign:2.1.0"
     exon            1110..1257
                     /gene="Kif9"
                     /inference="alignment:Splign:2.1.0"
     exon            1258..1322
                     /gene="Kif9"
                     /inference="alignment:Splign:2.1.0"
     exon            1323..1400
                     /gene="Kif9"
                     /inference="alignment:Splign:2.1.0"
     exon            1401..1469
                     /gene="Kif9"
                     /inference="alignment:Splign:2.1.0"
     exon            1470..1574
                     /gene="Kif9"
                     /inference="alignment:Splign:2.1.0"
     exon            1575..1630
                     /gene="Kif9"
                     /inference="alignment:Splign:2.1.0"
     exon            1631..1721
                     /gene="Kif9"
                     /inference="alignment:Splign:2.1.0"
     exon            1722..1855
                     /gene="Kif9"
                     /inference="alignment:Splign:2.1.0"
     exon            1856..2050
                     /gene="Kif9"
                     /inference="alignment:Splign:2.1.0"
     exon            2051..2265
                     /gene="Kif9"
                     /inference="alignment:Splign:2.1.0"
     exon            2266..2442
                     /gene="Kif9"
                     /inference="alignment:Splign:2.1.0"
     exon            2443..2558
                     /gene="Kif9"
                     /inference="alignment:Splign:2.1.0"
     exon            2559..2663
                     /gene="Kif9"
                     /inference="alignment:Splign:2.1.0"
     exon            2664..3379
                     /gene="Kif9"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2974..2979
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Kif9"
                     /note="hexamer: TATAAA"
     polyA_site      2995
                     /gene="Kif9"
                     /note="major polyA site"
     regulatory      3151..3156
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Kif9"
                     /note="hexamer: AATAAA"
     polyA_site      3190
                     /gene="Kif9"
     regulatory      3350..3355
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Kif9"
                     /note="hexamer: AATAAA"
     polyA_site      3379
                     /gene="Kif9"
                     /note="major polyA site"
ORIGIN      
        1 agtcggctag ctgtcctggt tgcgaacaga gctccctcaa gttgctgcag ttctagcggt
       61 cgctctaccc gagcgccact gccccgcgag tagtggctga agatggtgga cccacctatg
      121 gagattcagt caccctctga cttccagcca tgagtatcac catcaactac catttcttga
      181 gcacctggtg tgtgctgggc gctgttctgg accttgtggg gggcatcaca agaggtaaac
      241 ggcacgaccc ttatcctcaa gcagcttgta atttgacttg ggagctgaag cccacataaa
      301 tgaagcggca taagaacggt agcaagcagt acctcactaa aatgggtact aggaaaaagg
      361 ttcaagcgtt tgttcgagtc aggcctactg atgactttgc tcatgaaatg atcaaatatg
      421 gagaagacaa caaaagcatc gacatccact tgaagaagga cactcggaga ggggttgtca
      481 ataaccagca gacagactgg tccttcaagc tggatggagt gcttcacaat gcctcccagg
      541 acttggttta tgaaacagtt gccaaggatg cggtttctca agcccttgat gggtacaatg
      601 gtaccatcat gtgttacggg cagacaggag ccggcaagac atacaccatg acaggggcaa
      661 cggagaatta caagcaccgc ggaattctcc ctcgtgccct gcagcaggtg ttcaggatga
      721 ttgaagagcg tcccacgcac gccatcacag tccgtgtttc ctacctggaa atctacaatg
      781 agaacctgtt cgatctcctg tccactctgc cctacgtggg accctcagtc acaccaatga
      841 ccattgtgga aaaccctcaa gggatcttca ttaaaggctt gtcagtgcat ctcaccagtc
      901 aagaggagga cgccttcagc ctcctctttg agggcgagac caacaggatc attgcctccc
      961 acacgatgaa caagaactca tccaggtcgc actgcatttt caccatctac atggaggccc
     1021 actctcggac cttatcagat gaaaagtata tcacttctaa aatcaacctg gtagatctgg
     1081 caggctcaga gaggctcagc aagactgggt ctgaaggtag agtcctaaag gaagccacct
     1141 acatcaacaa gtcactgtca ttcctggagc aggccatcat tgcccttggg gaccagaatc
     1201 gggaccacgt ccctttccgg cagagcaagc tcacccatgc cctgaaagac tccttagggg
     1261 gaaactgtaa tatggtcctc gtgacaaaca tctatggaga agctgcccag ttggatgaaa
     1321 cgctgtcttc attgaggttt gccagcagga tgaagctggt caccactgag cctgccatca
     1381 atgagaagta tgatgctgag agaatggtca agaatttgga gaaggaactg gcattgctta
     1441 agcaggaact ggccatccat gatagtctgt ccaaccgcac ccttgtgaat tatgacccca
     1501 tggatgaaat tcagattgct gagatcaact ctcaagtacg gaggtacctg gaggggacgc
     1561 tggacgagat tgacataatc aatctaaggc agattcagga ggtattcaac cagttcaggg
     1621 tggttctgag ccaacaggag caggaagtag agtctgcctt gcgcaggaag tacactctca
     1681 tagacaaaaa tgattttgca gccatttctg ctgtccagaa ggtggggctt atggatatag
     1741 aaggtaacct agtaggtgag cccgatggac aaagctttgg acttggagtt gctccgtttt
     1801 ctgtcaaacc tgggaagaaa cctaagacca agaagacacc gaaggaccag ttcagctcct
     1861 cagcaagaaa ggaaggtgcc agtagccctg tgagtggcaa ggactttgat gtggcttcca
     1921 tctccaagac ccagctgatc ccatcttcca aagatgggga tctcaaagac atgcttgcac
     1981 gagagagaga aacttccagc attgaacccc ttatctcaga ctctccaaag gaagaattac
     2041 gtgcgcccag acccagcacc ccaccctcta ggactgtggc ctttgaagaa tttaagaatg
     2101 aacgaggtag tgagatcaac cgcatcttca aagaaaacaa atccatctta aatgaacgga
     2161 agaaaagggc cagcgagaca acccagcgca tcaacgccat caagcaggag attgatgaga
     2221 ccaaagatgc actcaatttc cagaaatcac ttcgggagaa gcaaggagag tacgagaaca
     2281 aaggcctgat gatcatcgac gaggaggaat ttctgttgat cctgaagctc aaagacctga
     2341 agaagcagta tcgaaatgag taccaggaac ttagagacct ccgggctgag atccaatact
     2401 gccagcgcct ggtggatcag tgtcgccatc gcctgctcat ggaatttgac atctggtaca
     2461 atgagtcttt tatgatccca gaggacgttc aggtagcact gaagctaggc agcagcatcc
     2521 ggccaggaat ggtgcctatc agcaggattg tgtgtctggg agaagatgac caggacaggt
     2581 tcagccatct gcagcagact gtcctgcctg aaggtcttga ttccatcacc ttctacaatg
     2641 ccaaagtcaa gacagatcag aaggcttatg gtagcatcag aagagcatgg tggagagctg
     2701 cttgtatcat caacgcgctc aatctgagaa ggactggggt ggatcaagga tatgataaac
     2761 ctatcaggcc ataaccccag tgacctacat cctccaacct gctcctacct cttgcgtccc
     2821 accaccttcc actaacgcta tcaagttatg aatccaatgg tggataaatt cgttgattag
     2881 ctctcacttt cctattacct ctcaatgatc agatctaccc atggagacta agcttgcaaa
     2941 cacaggaacc tatatgcttt aaggtatata gtatataaag tacttcatat ccaaactatt
     3001 gttggggtat attgtgtgaa ggttgtcttt gtatttttca attgttaatt ctgtaacagc
     3061 aaacctgaac tttgatattg ttattcttat ggctcatcac ctgcctcagt attttgtaaa
     3121 catacacctt cttcatttac tgattggttt aataaagatc tgatggccaa cagctgggca
     3181 ggaaagggaa gtcgggactt ctctggactg agaggatctc tgggaaaaga gtcatggaca
     3241 gttgggttac taagttagat gagctagctg ggaggtagcc taagctataa taaaattaat
     3301 aagtctctgt gtcattattc gtccactggt gggtccaaga gagtccaaca ataaactata
     3361 acatcttttc tcttttgaa
//
