LOCUS       NM_008449               6895 bp    mRNA    linear   ROD 01-MAY-2024
DEFINITION  Mus musculus kinesin family member 5C (Kif5c), mRNA.
ACCESSION   NM_008449
VERSION     NM_008449.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6895)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 6895)
  AUTHORS   Meziane,H., Birling,M.C., Wendling,O., Leblanc,S., Dubos,A.,
            Selloum,M., Pavlovic,G., Sorg,T., Kalscheuer,V.M., Billuart,P.,
            Laumonnier,F., Chelly,J., van Bokhoven,H. and Herault,Y.
  TITLE     Large-Scale Functional Assessment of Genes Involved in Rare
            Diseases with Intellectual Disabilities Unravels Unique
            Developmental and Behaviour Profiles in Mouse Models
  JOURNAL   Biomedicines 10 (12), 3148 (2022)
   PUBMED   36551904
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 6895)
  AUTHORS   Li,W., Cheng,T., Dong,X., Chen,H., Yang,L., Qiu,Z. and Zhou,W.
  TITLE     KIF5C deficiency causes abnormal cortical neuronal migration,
            dendritic branching, and spine morphology in mice
  JOURNAL   Pediatr Res 92 (4), 995-1002 (2022)
   PUBMED   34966180
  REMARK    GeneRIF: KIF5C deficiency causes abnormal cortical neuronal
            migration, dendritic branching, and spine morphology in mice.
REFERENCE   4  (bases 1 to 6895)
  AUTHORS   Chassefeyre,R., Chaiamarit,T., Verhelle,A., Novak,S.W.,
            Andrade,L.R., Leitao,A.D.G., Manor,U. and Encalada,S.E.
  TITLE     Endosomal sorting drives the formation of axonal prion protein
            endoggresomes
  JOURNAL   Sci Adv 7 (52), eabg3693 (2021)
   PUBMED   34936461
REFERENCE   5  (bases 1 to 6895)
  AUTHORS   Race,B., Williams,K., Baune,C., Striebel,J.F., Winkler,C.W.,
            Carroll,J.A., Encalada,S.E. and Chesebro,B.
  TITLE     Deletion of Kif5c Does Not Alter Prion Disease Tempo or Spread in
            Mouse Brain
  JOURNAL   Viruses 13 (7), 1391 (2021)
   PUBMED   34372599
  REMARK    GeneRIF: Deletion of Kif5c Does Not Alter Prion Disease Tempo or
            Spread in Mouse Brain.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 6895)
  AUTHORS   Kanai,Y., Okada,Y., Tanaka,Y., Harada,A., Terada,S. and Hirokawa,N.
  TITLE     KIF5C, a novel neuronal kinesin enriched in motor neurons
  JOURNAL   J Neurosci 20 (17), 6374-6384 (2000)
   PUBMED   10964943
REFERENCE   7  (bases 1 to 6895)
  AUTHORS   Kriebel,P., Patel,B.K., Nelson,S.A., Grusby,M.J. and
            LaRochelle,W.J.
  TITLE     Consequences of Stat6 deletion on Sis/PDGF- and IL-4-induced
            proliferation and transcriptional activation in murine fibroblasts
  JOURNAL   Oncogene 18 (51), 7294-7302 (1999)
   PUBMED   10602484
REFERENCE   8  (bases 1 to 6895)
  AUTHORS   Xia,Ch., Rahman,A., Yang,Z. and Goldstein,L.S.
  TITLE     Chromosomal localization reveals three kinesin heavy chain genes in
            mouse
  JOURNAL   Genomics 52 (2), 209-213 (1998)
   PUBMED   9782088
REFERENCE   9  (bases 1 to 6895)
  AUTHORS   Nakagawa,T., Tanaka,Y., Matsuoka,E., Kondo,S., Okada,Y., Noda,Y.,
            Kanai,Y. and Hirokawa,N.
  TITLE     Identification and classification of 16 new kinesin superfamily
            (KIF) proteins in mouse genome
  JOURNAL   Proc Natl Acad Sci U S A 94 (18), 9654-9659 (1997)
   PUBMED   9275178
  REMARK    Erratum:[Proc Natl Acad Sci U S A 1999 Mar 30;96(7):4214]
REFERENCE   10 (bases 1 to 6895)
  AUTHORS   Nangaku,M., Sato-Yoshitake,R., Okada,Y., Noda,Y., Takemura,R.,
            Yamazaki,H. and Hirokawa,N.
  TITLE     KIF1B, a novel microtubule plus end-directed monomeric motor
            protein for transport of mitochondria
  JOURNAL   Cell 79 (7), 1209-1220 (1994)
   PUBMED   7528108
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CJ113909.1 and BC067051.1.
            
            On Apr 24, 2018 this sequence version replaced NM_008449.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC067051.1, SRR1660811.109669.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164132
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-28                CJ113909.1         1-28
            29-6895             BC067051.1         1-6867
FEATURES             Location/Qualifiers
     source          1..6895
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 28.68 cM"
     gene            1..6895
                     /gene="Kif5c"
                     /gene_synonym="Khc; KINN; NKHC; NKHC2"
                     /note="kinesin family member 5C"
                     /db_xref="GeneID:16574"
                     /db_xref="MGI:MGI:1098269"
     exon            1..502
                     /gene="Kif5c"
                     /gene_synonym="Khc; KINN; NKHC; NKHC2"
                     /inference="alignment:Splign:2.1.0"
     CDS             377..3247
                     /gene="Kif5c"
                     /gene_synonym="Khc; KINN; NKHC; NKHC2"
                     /note="kinesin heavy chain neuron-specific 2; kinesin
                     heavy chain member 5C; kinesin-1"
                     /codon_start=1
                     /product="kinesin heavy chain isoform 5C"
                     /protein_id="NP_032475.2"
                     /db_xref="CCDS:CCDS16024.1"
                     /db_xref="GeneID:16574"
                     /db_xref="MGI:MGI:1098269"
                     /translation="MADPAECSIKVMCRFRPLNEAEILRGDKFIPKFKGEETVVIGQG
                     KPYVFDRVLPPNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHD
                     PQLMGIIPRIAHDIFDHIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLAVHEDK
                     NRVPYVKGCTERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENV
                     ETEKKLSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGTKTH
                     VPYRDSKMTRILQDSLGGNCRTTIVICCSPSVFNEAETKSTLMFGQRAKTIKNTVSVN
                     LELTAEEWKKKYEKEKEKNKALKSVLQHLEMELNRWRNGEAVPEDEQISAKDQKSLEP
                     CDNTPIIDNITPVVDGISAEKEKYDEEITSLYRQLDDKDDEINQQSQLAEKLKQQMLD
                     QDELLASTRRDYEKIQEELTRLQIENEAAKDEVKEVLQALEELAVNYDQKSQEVEDKT
                     RANEQLTDELAQKTTTLTTTQRELSQLQELSNHQKKRATEILNLLLKDLGEIGGIIGT
                     NDVKTLADVNGVIEEEFTMARLYISKMKSEVKSLVNRSKQLESAQMDSNRKMNASERE
                     LAACQLLISQHEAKIKSLTDYMQNMEQKRRQLEESQDSLSEELAKLRAQEKMHEVSFQ
                     DKEKEHLTRLQDAEEVKKALEQQMESHREAHQKQLSRLRDEIEEKQRIIDEIRDLNQK
                     LQLEQERLSSDYNKLKIEDQEREVKLEKLLLLNDKREQAREDLKGLEETVSRELQTLH
                     NLRKLFVQDLTTRVKKSVELDSDDGGGSAAQKQKISFLENNLEQLTKVHKQLVRDNAD
                     LRCELPKLEKRLRATAERVKALESALKEAKENAMRDRKRYQQEVDRIKEAVRAKNMAR
                     RAHSAQIAKPIRPGHYPASSPTAVHAVRGGGGGSSNSTHYQK"
     exon            503..593
                     /gene="Kif5c"
                     /gene_synonym="Khc; KINN; NKHC; NKHC2"
                     /inference="alignment:Splign:2.1.0"
     exon            594..667
                     /gene="Kif5c"
                     /gene_synonym="Khc; KINN; NKHC; NKHC2"
                     /inference="alignment:Splign:2.1.0"
     exon            668..772
                     /gene="Kif5c"
                     /gene_synonym="Khc; KINN; NKHC; NKHC2"
                     /inference="alignment:Splign:2.1.0"
     exon            773..821
                     /gene="Kif5c"
                     /gene_synonym="Khc; KINN; NKHC; NKHC2"
                     /inference="alignment:Splign:2.1.0"
     exon            822..877
                     /gene="Kif5c"
                     /gene_synonym="Khc; KINN; NKHC; NKHC2"
                     /inference="alignment:Splign:2.1.0"
     exon            878..965
                     /gene="Kif5c"
                     /gene_synonym="Khc; KINN; NKHC; NKHC2"
                     /inference="alignment:Splign:2.1.0"
     exon            966..1090
                     /gene="Kif5c"
                     /gene_synonym="Khc; KINN; NKHC; NKHC2"
                     /inference="alignment:Splign:2.1.0"
     exon            1091..1195
                     /gene="Kif5c"
                     /gene_synonym="Khc; KINN; NKHC; NKHC2"
                     /inference="alignment:Splign:2.1.0"
     exon            1196..1344
                     /gene="Kif5c"
                     /gene_synonym="Khc; KINN; NKHC; NKHC2"
                     /inference="alignment:Splign:2.1.0"
     exon            1345..1493
                     /gene="Kif5c"
                     /gene_synonym="Khc; KINN; NKHC; NKHC2"
                     /inference="alignment:Splign:2.1.0"
     exon            1494..1666
                     /gene="Kif5c"
                     /gene_synonym="Khc; KINN; NKHC; NKHC2"
                     /inference="alignment:Splign:2.1.0"
     exon            1667..1735
                     /gene="Kif5c"
                     /gene_synonym="Khc; KINN; NKHC; NKHC2"
                     /inference="alignment:Splign:2.1.0"
     exon            1736..1942
                     /gene="Kif5c"
                     /gene_synonym="Khc; KINN; NKHC; NKHC2"
                     /inference="alignment:Splign:2.1.0"
     exon            1943..2089
                     /gene="Kif5c"
                     /gene_synonym="Khc; KINN; NKHC; NKHC2"
                     /inference="alignment:Splign:2.1.0"
     exon            2090..2278
                     /gene="Kif5c"
                     /gene_synonym="Khc; KINN; NKHC; NKHC2"
                     /inference="alignment:Splign:2.1.0"
     exon            2279..2396
                     /gene="Kif5c"
                     /gene_synonym="Khc; KINN; NKHC; NKHC2"
                     /inference="alignment:Splign:2.1.0"
     exon            2397..2473
                     /gene="Kif5c"
                     /gene_synonym="Khc; KINN; NKHC; NKHC2"
                     /inference="alignment:Splign:2.1.0"
     exon            2474..2583
                     /gene="Kif5c"
                     /gene_synonym="Khc; KINN; NKHC; NKHC2"
                     /inference="alignment:Splign:2.1.0"
     exon            2584..2685
                     /gene="Kif5c"
                     /gene_synonym="Khc; KINN; NKHC; NKHC2"
                     /inference="alignment:Splign:2.1.0"
     exon            2686..2746
                     /gene="Kif5c"
                     /gene_synonym="Khc; KINN; NKHC; NKHC2"
                     /inference="alignment:Splign:2.1.0"
     exon            2747..2818
                     /gene="Kif5c"
                     /gene_synonym="Khc; KINN; NKHC; NKHC2"
                     /inference="alignment:Splign:2.1.0"
     exon            2819..2923
                     /gene="Kif5c"
                     /gene_synonym="Khc; KINN; NKHC; NKHC2"
                     /inference="alignment:Splign:2.1.0"
     exon            2924..3140
                     /gene="Kif5c"
                     /gene_synonym="Khc; KINN; NKHC; NKHC2"
                     /inference="alignment:Splign:2.1.0"
     exon            3141..3253
                     /gene="Kif5c"
                     /gene_synonym="Khc; KINN; NKHC; NKHC2"
                     /inference="alignment:Splign:2.1.0"
     exon            3254..6868
                     /gene="Kif5c"
                     /gene_synonym="Khc; KINN; NKHC; NKHC2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      6846..6851
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Kif5c"
                     /gene_synonym="Khc; KINN; NKHC; NKHC2"
                     /note="hexamer: AATAAA"
     polyA_site      6868
                     /gene="Kif5c"
                     /gene_synonym="Khc; KINN; NKHC; NKHC2"
                     /note="major polyA site"
ORIGIN      
        1 gaggggcggg cctggaggtg ccggagcacg gtggtgctga tgcaggatgg ctgagcgcga
       61 ccgagcccgg gaggtctgag ccgggcgggg attgctccct gagcatcgcc tagtccgccc
      121 gcctcgtggt tgcgggcagg tgggccgggg gcgcaggacc gggctggagg tcagcagcag
      181 ggcggcccac ctgatacgct gctctccttc ccggcggcgg agctgcgggg cgtccagcgc
      241 aggcttgaga tgacctgctg agaagctgcg ggaggcggcc tagcagcggg cagcggttgg
      301 ttcgcggcct cctcggtggc gctgcccagc cgggcccccc accccatccc tgtgccccct
      361 cctgctgcgg cccgagatgg cggatccagc cgaatgcagc atcaaagtga tgtgccggtt
      421 ccggcccctc aacgaagcgg agatcctccg cggggacaaa ttcatcccca aattcaaagg
      481 cgaggagacg gtggtgatcg ggcaagggaa gccgtatgtc tttgaccgag tgctgccgcc
      541 caacacaacc caggagcagg tctacaatgc ctgtgcaaag cagattgtca aagatgtcct
      601 tgagggttat aatggaacaa tttttgcata tgggcagact tcatcaggaa aaactcatac
      661 catggagggg aagttacatg atcctcagct tatgggtatc attccaagga ttgcacatga
      721 tatttttgat cacatctatt ccatggacga gaacctggag tttcatatca aggtttccta
      781 ttttgagatc tacttggaca aaataaggga cttgcttgat gtgtccaaga ccaacttggc
      841 agttcatgaa gacaaaaaca gagtccccta tgtaaagggg tgcaccgaga ggtttgtgtc
      901 aagcccggag gaggtcatgg atgtgatcga tgagggcaaa gcaaaccgac acgtggctgt
      961 gacaaacatg aacgaacaca gctctaggag tcacagtatc ttcctgatta acattaagca
     1021 agagaatgtg gagactgaaa aaaaactcag cgggaagctg tatttggttg atttggctgg
     1081 gagtgaaaag gtcagcaaaa ccggtgccga gggagctgtt cttgatgaag ctaaaaatat
     1141 caacaagtct ttgtctgctc ttggaaatgt gatttctgcc ttggcagaag ggacaaaaac
     1201 acatgtaccg taccgggaca gcaagatgac tcggattctc caggactctc tgggtgggaa
     1261 ctgtaggacc accattgtca tttgctgttc tccttcagtc ttcaatgaag ccgagaccaa
     1321 gtccacgctg atgtttggac agagagcaaa gaccatcaag aatacagtct ctgtgaactt
     1381 ggaactaaca gcagaagagt ggaagaagaa atatgaaaaa gagaaagaga agaacaaggc
     1441 cttgaagagt gtcctccagc atctggagat ggagctgaac aggtggagga acggggaagc
     1501 tgtacccgag gacgaacaga tcagcgccaa ggaccagaag agcctagagc cctgtgacaa
     1561 cacacccatc atagacaaca tcacgcctgt tgtggacggc atctctgccg agaaggagaa
     1621 gtatgacgag gagatcacca gtttgtaccg acagctcgat gataaggatg atgaaattaa
     1681 ccagcagagc cagctggctg aaaagctgaa gcaacagatg ttggatcagg atgagctcct
     1741 ggcttccacg agaagggact atgagaagat ccaggaggag ctgacacgcc tccagatcga
     1801 aaatgaggca gctaaagacg aagtgaaaga agtcctccag gccctggagg agctggctgt
     1861 caattacgac cagaagtcac aagaagtgga ggacaagacc agggccaacg agcaactgac
     1921 tgatgagctg gcccagaaaa cgacgacact gacaaccacc cagcgagagc tgagtcagct
     1981 gcaagagctt agtaaccacc agaaaaagag ggccacagag atcctgaacc tgcttctcaa
     2041 ggacctgggg gagataggcg gaattattgg caccaacgat gtgaagactc tggcagatgt
     2101 gaacggggtc attgaggagg agttcaccat ggcacgcctg tacattagca agatgaagtc
     2161 ggaggtcaag tctctcgtga accgcagcaa gcagctggag agtgcccaga tggactctaa
     2221 caggaagatg aacgccagtg agcgcgagct ggcagcgtgc cagttgctta tctcacagca
     2281 cgaagccaag atcaagtctc tgacagacta catgcagaac atggaacaga agaggcggca
     2341 gctggaagag tcccaggact ccctcagcga ggaactggcc aagctccggg cccaggaaaa
     2401 aatgcacgaa gtcagtttcc aagataagga aaaggagcac ctgacgaggc tgcaggatgc
     2461 tgaggaggtg aagaaagctc tggagcagca gatggagagc caccgggaag cgcaccaaaa
     2521 gcagctgtcc agacttcgcg atgagattga ggagaagcag agaatcattg atgagatccg
     2581 ggatttgaat cagaaactgc aactggaaca ggagaggctc agctctgatt ataacaagct
     2641 gaaaatagag gaccaggaga gagaagtgaa actggagaag ctcctattgc tcaatgacaa
     2701 aagggagcaa gccagggagg acctcaaggg actggaggag actgtgtcta gagaactcca
     2761 gacccttcat aacctgcgca aactcttcgt ccaggatttg acaacccggg tgaaaaagag
     2821 tgtggagctg gacagcgacg atggaggggg cagcgctgct cagaagcaga agatctcctt
     2881 cctggagaac aacctggaac agcttaccaa ggtgcacaag cagctggtcc gggacaatgc
     2941 agatttgcgc tgtgaactcc ccaagctgga gaagaggctt cgtgctaccg cagaacgcgt
     3001 caaggccttg gagagtgcgc tgaaagaggc caaggagaat gccatgaggg accgaaaacg
     3061 ctaccagcag gaagtagatc gcatcaagga ggctgtgcga gccaagaaca tggccaggag
     3121 ggcacattcg gctcagatcg ccaagcccat ccgcccaggc cattacccag catcatctcc
     3181 gacagctgtc catgccgtcc gaggaggagg aggtggctct tcaaactcta ctcactacca
     3241 gaaataaagc agaatatgac tccacgtagc atgaaaagga ctgtagtagt caccagttcc
     3301 tttctgtccc ctcctataca gtttccgttt ctttttacac ttgcttgccc agccgtctgt
     3361 agtacaccag attcaggtgt ttgcgctgtg tagaatttgt gtgcacagat acgtgcttgg
     3421 atccttctcc taagaagttg gaaggagggg gttacgcaat acccacttcc tgctcagacc
     3481 tcgccacttc tcagcctccg gggttgtgtg gtctctggag gcccctgcag tgcactggcc
     3541 ccttggaatg gaacgccctg ctgtgccatc ctagagggac aatcaagtgc agtggaacca
     3601 gtgaccacgc tctgcctcga cttctggttt cctgtaaaat aaacacatta ctttatattt
     3661 ttagggaaca aaaaaaaagt gctgctatag ggttcaaaat tttcattctg aacacttttc
     3721 caaaaccaac cccagagagc attttaaata tcctggtcat atctttggat ctgtaaaata
     3781 gaccttttag tatggcacct gttaaaatgc aaagcagatt ccttcaaggc agaaaaacag
     3841 tttgacaata gcagtgtaga atttgctcat tcagacacat ctatgaaaat gcgaagagtc
     3901 acagaattca cctccaagct gctcgctggt gaacctgcag tgactagtcc tggccagccc
     3961 agttgtttga acatcattcc tatacaagag ttgaaaatgc tgcagaattg ggtgagtgga
     4021 gatggggctg cctcccctcc tcacagcttc ctccggatgc cctggaagct gccttgggct
     4081 cgcctctttt tctagcaaac catcgcgtgc tggaggagat attcctaaag agatccagcg
     4141 tcagtacagt agttggaaaa gaattccctc aggggaaagt cattggtgag atttatgcct
     4201 tgtctgtttt tattgtaacc tatcattgca aactgctgat ttgaattctt tctttggcac
     4261 cagataggct ttttcttctt tgaggcacag ttagggggga aaaatcagta taactggatt
     4321 ggggtttgtt tgtttgtttg tttgttttgg ggttttttat ttgttttttg tatatttaat
     4381 tattacttta ttcagatcca tgaatcgaaa ggtgactacg ttcagttggg catactaaaa
     4441 ggatcagttg ccaagtagtc aagcgtttca agagaaactg gcaggcttca gtgagtcgct
     4501 actatgtgct gctatttgtt ttcatgaatt tgtggtttag atagtaacat ccccattcat
     4561 ctcagagaaa tgacccatcc tgtcatctta tgtgcccaag aagtgtgagc tcacaccttc
     4621 ttctgaagct ggtacccctg gagtaagggg agactctagg ctttctcaag gctgtgaggg
     4681 tggggtagaa aaagttaatg tgtgtgctta tgcacatgcg tgtgtgaaat gttgatggct
     4741 gtgtatatta cctccaggat tctgttgtat agtcctttcc taacactgat ttgacttaat
     4801 ttatttgtta gatgttgccc tttataacag tgttttgttt ttaattaggt gtgaaaagaa
     4861 gacaacttct attgaagtat ttattttaca aagatgattt tgtgtttacc tgtgttcact
     4921 ttgtttcatg ttgttgccac tgttggctgc tattggagtc tgatggaggg gtcctttgca
     4981 gggcaagtct gcaaaccccg tcagtaccaa ctgatgccag gttagaagct tgctgtctat
     5041 gtttgcttct gactcggaaa ctgaaacgtt ggcctttaag agggctacca atgggatgcg
     5101 tcttgtctag aggacctgct attgtctttt agacttgtgt ttagaaactg ggtacgggtc
     5161 agtaataccc cattcttggc tttcattagc agccattata aaatggatga ttttagattc
     5221 tttctaaagc acttttcccc ctaggttccc attttctact tctgaagagt tgtggggcac
     5281 tttcaagttt taaaaggcag cattcgtttg tagttcacat tacttgatct ctacaagggc
     5341 cttacaaaat tcactgtact tttattcaca gagaaagttg gctttgatgt cttttagaga
     5401 taattctgct agttgctgat cagccagtca gttcatctag cgccagtctt tataagacct
     5461 ctaatcgaat tttctcacac tgtgactaaa agctaggcac gtcattggaa cagatcatgt
     5521 ggtttattca agcaatccct aatctcacat tgtctattaa ttcctttatc agaacagtgt
     5581 gctctcgggc cgctttttta aaaggccatg tttataaagt tttcattgtt tgacaggctg
     5641 ttacattcta tattctagct gtaaaaatcc cacttctgaa cagccaagtg gatggctcca
     5701 tttcgtcaca tgtttcacat tgctggaatg tatgccagtg tatgttctct gaataattta
     5761 ctatctcatg cctacttctt gaaagtttac tctgagatgc cgtaggagtg cagccagatg
     5821 gtttagacaa ataacctctg cctgccagcc gttggggtga tgattagaat gttattgaag
     5881 atagtggtta tggttggggc ttataatgcc gactgcattt gatcagtcct tagagaatcc
     5941 tgaatgtagg tctcatctct tcaaatgctg agcagtttgc tttagtgggc atcaggtaaa
     6001 acagtcagag gtgttagcct tttaaaagac ggagaatcac atggtgaaga attcatagaa
     6061 gtgttgtaat aaatgaaggg ctaaaaatgt ttgactagaa tgtagatcca gtgacacctt
     6121 gaagcctcca agtccatata gagatgtgag cttgagggaa tggggtttgt gtcagcttct
     6181 ctttcctaga atagctaaag gatcgtaaag cttcagtcac cccttccttt gtagggcagg
     6241 cgccacgggg actctgggta gaagacattg ggggacactt gtcattagca gaagtttgtc
     6301 attgggcagg ttttacttca ttgtcccatg ctggctatct tgagcaagct aaagaaccat
     6361 cactgtttaa aactgcttcc taacagggtt ttgagtttta aacaactgtt gagtaaggac
     6421 cagataactg ccaaaggaaa cactggtctg tgaagtctgc ttatttactg agaactgtgt
     6481 atcaactttt aaacacttcc catgtgtgca gataaaaggg gaatagggct ttctgtagaa
     6541 ttctatctgt ctagtttgta aagtgtcatg tgtactgcag atgtctgttc tctgggcttt
     6601 atgttctgta cagtagattt cattaagaaa aattgtggac aaacttgttt ctgtggtttg
     6661 atgggggaga atggcgatgt gtatttaaat agctatcctg tgagatagaa atgtccccaa
     6721 agatctggaa gtaaccctcc ctggccctcg gaaaactctg gctatctcct aggttctaaa
     6781 atgaagatgt atggatactc tggcagactg catgttgtat aatttgaaaa tactcaaaac
     6841 tggacaataa aactgagtta aactttgaaa aaaaaaaaaa aaaaaaaaaa aaaaa
//
