LOCUS       NM_001374727            5655 bp    mRNA    linear   ROD 31-DEC-2024
DEFINITION  Mus musculus kinesin family member 2A (Kif2a), transcript variant
            3, mRNA.
ACCESSION   NM_001374727 XM_006517535
VERSION     NM_001374727.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5655)
  AUTHORS   Dey,S., Kovalenko,A. and Yaron,A.
  TITLE     Protocol for semiautomated analysis of sensory neuronal innervation
            of the mouse footpad skin
  JOURNAL   STAR Protoc 5 (4), 103312 (2024)
   PUBMED   39298322
REFERENCE   2  (bases 1 to 5655)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 5655)
  AUTHORS   Dey,S., Barkai,O., Gokhman,I., Suissa,S., Haffner-Krausz,R.,
            Wigoda,N., Feldmesser,E., Ben-Dor,S., Kovalenko,A., Binshtok,A. and
            Yaron,A.
  TITLE     Kinesin family member 2A gates nociception
  JOURNAL   Cell Rep 42 (10), 113257 (2023)
   PUBMED   37851573
REFERENCE   4  (bases 1 to 5655)
  AUTHORS   Ruiz-Reig,N., Garcia-Sanchez,D., Schakman,O., Gailly,P. and
            Tissir,F.
  TITLE     Inhibitory synapse dysfunction and epileptic susceptibility
            associated with KIF2A deletion in cortical interneurons
  JOURNAL   Front Mol Neurosci 15, 1110986 (2023)
   PUBMED   36733270
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 5655)
  AUTHORS   Ruiz-Reig,N., Chehade,G., Hakanen,J., Aittaleb,M., Wierda,K., De
            Wit,J., Nguyen,L., Gailly,P. and Tissir,F.
  TITLE     KIF2A deficiency causes early-onset neurodegeneration
  JOURNAL   Proc Natl Acad Sci U S A 119 (46), e2209714119 (2022)
   PUBMED   36343267
  REMARK    GeneRIF: KIF2A deficiency causes early-onset neurodegeneration.
REFERENCE   6  (bases 1 to 5655)
  AUTHORS   Miki,H., Setou,M., Kaneshiro,K. and Hirokawa,N.
  TITLE     All kinesin superfamily protein, KIF, genes in mouse and human
  JOURNAL   Proc Natl Acad Sci U S A 98 (13), 7004-7011 (2001)
   PUBMED   11416179
  REMARK    Review article
REFERENCE   7  (bases 1 to 5655)
  AUTHORS   Santama,N., Krijnse-Locker,J., Griffiths,G., Noda,Y., Hirokawa,N.
            and Dotti,C.G.
  TITLE     KIF2beta, a new kinesin superfamily protein in non-neuronal cells,
            is associated with lysosomes and may be implicated in their
            centrifugal translocation
  JOURNAL   EMBO J 17 (20), 5855-5867 (1998)
   PUBMED   9774330
REFERENCE   8  (bases 1 to 5655)
  AUTHORS   Nakagawa,T., Tanaka,Y., Matsuoka,E., Kondo,S., Okada,Y., Noda,Y.,
            Kanai,Y. and Hirokawa,N.
  TITLE     Identification and classification of 16 new kinesin superfamily
            (KIF) proteins in mouse genome
  JOURNAL   Proc Natl Acad Sci U S A 94 (18), 9654-9659 (1997)
   PUBMED   9275178
  REMARK    Erratum:[Proc Natl Acad Sci U S A 1999 Mar 30;96(7):4214]
REFERENCE   9  (bases 1 to 5655)
  AUTHORS   Noda,Y., Sato-Yoshitake,R., Kondo,S., Nangaku,M. and Hirokawa,N.
  TITLE     KIF2 is a new microtubule-based anterograde motor that transports
            membranous organelles distinct from those carried by kinesin heavy
            chain or KIF3A/B
  JOURNAL   J Cell Biol 129 (1), 157-167 (1995)
   PUBMED   7535303
REFERENCE   10 (bases 1 to 5655)
  AUTHORS   Aizawa,H., Sekine,Y., Takemura,R., Zhang,Z., Nangaku,M. and
            Hirokawa,N.
  TITLE     Kinesin family in murine central nervous system
  JOURNAL   J Cell Biol 119 (5), 1287-1296 (1992)
   PUBMED   1447303
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC154257.2 and AC154328.2.
            
            On Oct 10, 2019 this sequence version replaced XM_006517535.4.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR7974084.18302.1,
                                           SRR7345562.1719579.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164139 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-344               AC154257.2         112808-113151
            345-439             AC154257.2         141221-141315
            440-556             AC154257.2         141884-142000
            557-611             AC154257.2         145071-145125
            612-734             AC154257.2         147088-147210
            735-835             AC154257.2         147794-147894
            836-931             AC154257.2         150004-150099
            932-986             AC154257.2         151917-151971
            987-1149            AC154328.2         412-574
            1150-1240           AC154328.2         3531-3621
            1241-1304           AC154328.2         4063-4126
            1305-1396           AC154328.2         4983-5074
            1397-1539           AC154328.2         5970-6112
            1540-1744           AC154328.2         6238-6442
            1745-1855           AC154328.2         7617-7727
            1856-1923           AC154328.2         8536-8603
            1924-2037           AC154328.2         13281-13394
            2038-2188           AC154328.2         14310-14460
            2189-2290           AC154328.2         17979-18080
            2291-2426           AC154328.2         18622-18757
            2427-5655           AC154328.2         20874-24102
FEATURES             Location/Qualifiers
     source          1..5655
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 58.06 cM"
     gene            1..5655
                     /gene="Kif2a"
                     /gene_synonym="C530030B14Rik; Kif2; Kns2; M-kinesin"
                     /note="kinesin family member 2A"
                     /db_xref="GeneID:16563"
                     /db_xref="MGI:MGI:108390"
     exon            1..344
                     /gene="Kif2a"
                     /gene_synonym="C530030B14Rik; Kif2; Kns2; M-kinesin"
                     /inference="alignment:Splign:2.1.0"
     CDS             281..2512
                     /gene="Kif2a"
                     /gene_synonym="C530030B14Rik; Kif2; Kns2; M-kinesin"
                     /note="isoform 3 is encoded by transcript variant 3;
                     kinesin-like protein KIF2A; kinesin-2; kinesin heavy chain
                     member 2"
                     /codon_start=1
                     /product="kinesin-like protein KIF2A isoform 3"
                     /protein_id="NP_001361656.1"
                     /db_xref="CCDS:CCDS88521.1"
                     /db_xref="GeneID:16563"
                     /db_xref="MGI:MGI:108390"
                     /translation="MATANFGKIQIGIYVEIKRSDGRIHQAMVTSLNEDNESVTVEWI
                     ENGDTKGKEIDLESIFSLNPDLVPDEDIEPSPELPPPSSSSKVNKIVKNRRTVAAVKN
                     DPPPRDNRVVGSARARPSQLPEQSSSAQQNGSVSDISPVQAAKKEFGPPSRRKSNCVK
                     EVEKLQEKREKRRLQQQELREKRAQDVDATNPNYEIMCMIRDFRGSLDYRPLTTADPI
                     DEHRICVCVRKRPLNKKETQMKDLDVITIPSKDVVMVHEPKQKVDLTRYLENQTFRFD
                     YAFDDSAPNEMVYRFTARPLVETIFERGMATCFAYGQTGSGKTHTMGGDFSGKNQDCS
                     KGIYALAARDVFLMLKKPNYKKLELQVYATFFEIYSGKVFDLLNRKTKLRVLEDGKQQ
                     VQVVGLQEREVKCVEDVLKLIDIGNSCRTSGQTSANAHSSRSHAVFQIILRRKGKLHG
                     KFSLIDLAGNERGADTSSADRQTRLEGAEINKSLLALKECIRALGRNKPHTPFRASKL
                     TQVLRDSFIGENSRTCMIATISPGMASCENTLNTLRYANRVKEFGISPSDIPFSQGGG
                     SRPDLSPSYDYDDFSPSITRVKELTVNPAAAGDVHPIMHHPPSQIDDLETQWGVGSSP
                     QRDDLKLLCEQNEEEVSPQLFTFHEAVSQMVEMEEQVVEDHRAVFQESIRWIEDEKAL
                     LEMTEEVDYDVDSYATQLEAILEQKIDILTELRDKVKSFRAALQEEEQASKQINPKRP
                     RAL"
     exon            345..439
                     /gene="Kif2a"
                     /gene_synonym="C530030B14Rik; Kif2; Kns2; M-kinesin"
                     /inference="alignment:Splign:2.1.0"
     exon            440..556
                     /gene="Kif2a"
                     /gene_synonym="C530030B14Rik; Kif2; Kns2; M-kinesin"
                     /inference="alignment:Splign:2.1.0"
     exon            557..611
                     /gene="Kif2a"
                     /gene_synonym="C530030B14Rik; Kif2; Kns2; M-kinesin"
                     /inference="alignment:Splign:2.1.0"
     exon            612..734
                     /gene="Kif2a"
                     /gene_synonym="C530030B14Rik; Kif2; Kns2; M-kinesin"
                     /inference="alignment:Splign:2.1.0"
     exon            735..835
                     /gene="Kif2a"
                     /gene_synonym="C530030B14Rik; Kif2; Kns2; M-kinesin"
                     /inference="alignment:Splign:2.1.0"
     exon            836..931
                     /gene="Kif2a"
                     /gene_synonym="C530030B14Rik; Kif2; Kns2; M-kinesin"
                     /inference="alignment:Splign:2.1.0"
     exon            932..986
                     /gene="Kif2a"
                     /gene_synonym="C530030B14Rik; Kif2; Kns2; M-kinesin"
                     /inference="alignment:Splign:2.1.0"
     exon            987..1149
                     /gene="Kif2a"
                     /gene_synonym="C530030B14Rik; Kif2; Kns2; M-kinesin"
                     /inference="alignment:Splign:2.1.0"
     exon            1150..1240
                     /gene="Kif2a"
                     /gene_synonym="C530030B14Rik; Kif2; Kns2; M-kinesin"
                     /inference="alignment:Splign:2.1.0"
     exon            1241..1304
                     /gene="Kif2a"
                     /gene_synonym="C530030B14Rik; Kif2; Kns2; M-kinesin"
                     /inference="alignment:Splign:2.1.0"
     exon            1305..1396
                     /gene="Kif2a"
                     /gene_synonym="C530030B14Rik; Kif2; Kns2; M-kinesin"
                     /inference="alignment:Splign:2.1.0"
     exon            1397..1539
                     /gene="Kif2a"
                     /gene_synonym="C530030B14Rik; Kif2; Kns2; M-kinesin"
                     /inference="alignment:Splign:2.1.0"
     exon            1540..1744
                     /gene="Kif2a"
                     /gene_synonym="C530030B14Rik; Kif2; Kns2; M-kinesin"
                     /inference="alignment:Splign:2.1.0"
     exon            1745..1855
                     /gene="Kif2a"
                     /gene_synonym="C530030B14Rik; Kif2; Kns2; M-kinesin"
                     /inference="alignment:Splign:2.1.0"
     exon            1856..1923
                     /gene="Kif2a"
                     /gene_synonym="C530030B14Rik; Kif2; Kns2; M-kinesin"
                     /inference="alignment:Splign:2.1.0"
     exon            1924..2037
                     /gene="Kif2a"
                     /gene_synonym="C530030B14Rik; Kif2; Kns2; M-kinesin"
                     /inference="alignment:Splign:2.1.0"
     exon            2038..2188
                     /gene="Kif2a"
                     /gene_synonym="C530030B14Rik; Kif2; Kns2; M-kinesin"
                     /inference="alignment:Splign:2.1.0"
     exon            2189..2290
                     /gene="Kif2a"
                     /gene_synonym="C530030B14Rik; Kif2; Kns2; M-kinesin"
                     /inference="alignment:Splign:2.1.0"
     exon            2291..2426
                     /gene="Kif2a"
                     /gene_synonym="C530030B14Rik; Kif2; Kns2; M-kinesin"
                     /inference="alignment:Splign:2.1.0"
     exon            2427..5655
                     /gene="Kif2a"
                     /gene_synonym="C530030B14Rik; Kif2; Kns2; M-kinesin"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2778..2783
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Kif2a"
                     /gene_synonym="C530030B14Rik; Kif2; Kns2; M-kinesin"
                     /note="hexamer: AATAAA"
     polyA_site      2800
                     /gene="Kif2a"
                     /gene_synonym="C530030B14Rik; Kif2; Kns2; M-kinesin"
                     /note="major polyA site"
     regulatory      4047..4052
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Kif2a"
                     /gene_synonym="C530030B14Rik; Kif2; Kns2; M-kinesin"
                     /note="hexamer: AATGAA"
     polyA_site      4066
                     /gene="Kif2a"
                     /gene_synonym="C530030B14Rik; Kif2; Kns2; M-kinesin"
                     /note="major polyA site"
     regulatory      4086..4091
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Kif2a"
                     /gene_synonym="C530030B14Rik; Kif2; Kns2; M-kinesin"
                     /note="hexamer: AATATA"
     polyA_site      4113
                     /gene="Kif2a"
                     /gene_synonym="C530030B14Rik; Kif2; Kns2; M-kinesin"
     regulatory      4404..4409
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Kif2a"
                     /gene_synonym="C530030B14Rik; Kif2; Kns2; M-kinesin"
                     /note="hexamer: AATAAA"
     polyA_site      4432
                     /gene="Kif2a"
                     /gene_synonym="C530030B14Rik; Kif2; Kns2; M-kinesin"
     regulatory      4693..4698
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Kif2a"
                     /gene_synonym="C530030B14Rik; Kif2; Kns2; M-kinesin"
                     /note="hexamer: AATAAA"
     polyA_site      4713
                     /gene="Kif2a"
                     /gene_synonym="C530030B14Rik; Kif2; Kns2; M-kinesin"
     regulatory      4771..4776
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Kif2a"
                     /gene_synonym="C530030B14Rik; Kif2; Kns2; M-kinesin"
                     /note="hexamer: ATTAAA"
     polyA_site      4798
                     /gene="Kif2a"
                     /gene_synonym="C530030B14Rik; Kif2; Kns2; M-kinesin"
ORIGIN      
        1 actcttcccc cgcgccgcct cacggctgcg gccctcgctt cacccggacg cccggcgtgc
       61 gcgcccgccc gcccgcccgc ccgtccgccc gcccgtccgc ccgtccgccc gcaggcccgg
      121 ggcttcagcc cgctcgtccg ccgccgctct cgccgcggcc ccgctcgcgt ccacgctgcc
      181 tcccggaccg gcgcggacgc gggccaccgc tgcccctccc gccgccaccc cgccccctcc
      241 ccgcctgttt cgcccgcctg ccgccgctcc ggatgaggtg atggcaacgg ccaacttcgg
      301 caagatccag atcgggattt acgtggagat caagcgcagc gatggccgaa tacaccaagc
      361 aatggtaaca tctttaaatg aagataatga aagtgtaact gttgagtgga tagaaaatgg
      421 agatacgaaa ggcaaagaga ttgacttgga gagcatcttt tcacttaacc ctgaccttgt
      481 acctgatgaa gatattgagc ccagtccaga actacctcca ccctcgtcat cctcaaaagt
      541 taacaaaatt gtaaagaacc ggcggactgt ggcagctgtt aagaatgacc ctcccccgag
      601 agataataga gtggttggtt cagcacgcgc acggcctagt cagcttcctg agcaatcgtc
      661 ttctgcacaa cagaatggta gcgtttcaga tatatctcca gttcaagctg caaaaaagga
      721 gtttggccct ccttcacgta gaaaatccaa ttgtgtgaaa gaagtagaaa aattgcaaga
      781 aaaacgagaa aaaaggagat tgcaacagca agaacttaga gaaaaaagag cccaggatgt
      841 tgatgctaca aatccaaatt acgaaattat gtgtatgatc agagacttca gagggagctt
      901 ggattacaga cccctaacaa cagcagatcc tattgatgaa cataggatat gtgtttgtgt
      961 aagaaaacga ccactcaata aaaaagaaac tcaaatgaaa gatcttgatg tgatcacaat
     1021 ccctagtaaa gatgttgtga tggtccacga acccaaacag aaagtagact taacaaggta
     1081 cttagaaaat cagacatttc ggtttgatta cgccttcgat gactcagctc ctaatgaaat
     1141 ggtttacagg tttactgcta ggccactagt ggaaacaata tttgaaaggg gcatggctac
     1201 gtgctttgct tatgggcaga ctggaagtgg gaaaactcat actatgggtg gtgacttttc
     1261 aggaaagaac caggattgtt ctaagggaat ttatgcatta gcagctcgcg atgtcttttt
     1321 aatgctgaag aagccaaact ataagaaact agaacttcaa gtatatgcaa cattttttga
     1381 aatttatagt ggaaaggtgt ttgacttact aaataggaaa acaaaattaa gagtactaga
     1441 agatgggaag cagcaggtcc aagtggtggg gctgcaggag cgggaggtga agtgtgtgga
     1501 ggacgtgctg aagctcatcg acataggcaa cagctgcaga acatctggcc aaacatctgc
     1561 aaatgcacat tcatctcgga gccatgcagt gttccagatc attctaagaa ggaaggggaa
     1621 actacatggt aaattttctc tcattgacct ggctgggaac gaaagaggag ctgatacatc
     1681 cagtgcagac aggcaaacca ggcttgaagg tgctgaaatt aataaaagcc ttttagcact
     1741 caaggagtgc atccgagcct taggtagaaa caaaccccat acgcctttcc gagcgagcaa
     1801 actcactcag gtgctgagag attccttcat aggtgaaaat tctcgtacct gcatgattgc
     1861 cacaatctct ccaggaatgg catcctgtga aaatactctt aatacgttaa gatatgcaaa
     1921 tagagtaaag gagtttggaa ttagtccttc agacattccc ttctcccagg gtggtggcag
     1981 tcgccctgat ctctctcctt cttacgatta tgacgacttt tctccttcaa ttaccagggt
     2041 gaaagaattg actgtaaatc cagctgctgc tggcgatgtc catccaataa tgcaccatcc
     2101 accgagccag attgatgact tagagacaca gtggggtgtg gggagttctc ctcagagaga
     2161 tgatctaaaa cttctctgtg aacaaaatga agaagaagtt tctccacagc tgttcacttt
     2221 ccatgaagct gtctcccaga tggtagagat ggaagagcag gttgtggaag atcatagggc
     2281 agtgttccag gaatccattc gctggataga agatgaaaag gctctcctag agatgactga
     2341 agaagtagac tatgatgtag actcatatgc tacacaactt gaagctattc ttgagcaaaa
     2401 aatagacatt ttaactgagt tacgagataa agtgaaatct tttcgcgcag cgctacaaga
     2461 agaagagcaa gcaagcaagc aaattaaccc caagaggccc cgagccctct aagttggcgt
     2521 ttgctactaa aggatcccca gaatccccaa tactgtaaca acggtggtcc gactgtaaag
     2581 gccacttgaa cgtttttgaa atcttttttt tttttttttt aacgtttttt gaaatcttaa
     2641 gtgtgtggaa aatatcttgt ccttcatctg aatgacattt caattttgtg aaacactcct
     2701 ttgtcgacaa aatgcttcta gaccaagagg cacaactaat aattcggact agtgaagtat
     2761 tttgtttcat ttgcccaaat aaatagtgat tgcttttgga tatccttgcc aattttattt
     2821 aaagattgtg gaagtgatcc agaagtggaa gataggggaa gccacagaat ttcctttaac
     2881 gcagatcaat tttcatagca agactgagca attttgaacc ctttgcgtgc atgcatacct
     2941 catgagtgat tgtacatact ttgcctactc ctagagacac tcgtgcttac tcatccttct
     3001 gtgccttggc taaggctatt gaccctagat ttctaaaaca gccgagatta attacattcc
     3061 ttgtttgtga ctgtaaatta cctttactgt gtgtacattt ttactgtatt tgagacattt
     3121 ttttgtgtgt gactagttaa ttttgcagga tgtgccatat caattgaacg gaactaaagt
     3181 ctgtgacagt ggacatagct gctggaccat tccatcttat gtgtaaagaa atctggaatt
     3241 atgtgattat aattttctta gcattttctt tgtaaaaaaa aacctaaaat atgaattagt
     3301 tggtgtatag taaaaagtaa agaaattctg agaggagttt tattttagga taatacatat
     3361 atacatatgc agtgtgtgtg ccagtggtgt taacaagact aatagtggaa tttggtcctt
     3421 aacaatgcca ttatttaagt tgaagtgttt attaactcac caaaatttaa tgtactgtta
     3481 aaggaaactg gcttctgatg catgaacatt tgtatgtaca ctgaaagtaa tccctaatac
     3541 aagttagata aaccaagcat agacagtatg tacccctgag aagtgttgat gacttatgag
     3601 gcaggttatt ccaagctcca tctaaaccta gtatgtgatg gtttttgaga atcatatttc
     3661 gcctgtagat tgatggcaaa ataggctact ctattaatgg cagcactcat ttttagctgc
     3721 taatctaaga aagaaaactg gccaattttc atgtaaatat tgtttaaaga tatatatatg
     3781 tatatctcta ggagttttcc cttggttccc actatctagt ccagtaggtt aaccaaagaa
     3841 cctcccatgg atctcttaac tctagggagc ctactgatga ctcagtgtac cgaggggaaa
     3901 tccatgaaga gtcatgagcc aggttcttta cttcactggt cataaatgat gagagtagct
     3961 ctgaggaatc cgaacaccat ggtgaaaact ctgtaaacat gaaatctaaa tcaaatgtag
     4021 attttttcac aatatgctta ttaataaatg aaatttatga aacgaattta gaaataatgt
     4081 acttcaatat aattagcttt gttttggaag gaactcaggt tttcttggag ttttatgcta
     4141 tattctattt gtgtttgttt caaagacggg aggaagaatg aaggactatt tctattgacc
     4201 ttgcagcagc tgtttaaaga aggtaatttt tgctgggtat agtggtgcat gcccttagtt
     4261 gcatccagca catggaagca gaggcaggta gatagatttc tgagttctgg accagcctgg
     4321 tatacatact aagttctagg acagccagag ctatgtacaa agaccttgcc tccagttctg
     4381 agaatgtctc atatatagtg ggcaataaag acacaaactt gctcataact tacctaacag
     4441 ttgagcttta atgttactgg cattggacag gtattatctt tgaaggtctt tatagataca
     4501 tgtttcctta ttggcttcgt cctgatctgt agtcagagta catcaataaa tatcttggta
     4561 ggtaaaatat gattcagctt tacggaggga aagctttagt tggaagaaaa taagctgaga
     4621 aagcctagtc tagcagaatt gtttccctaa ggtagagaat ggtacaagtg aactgtgcaa
     4681 agttgttctg acaataaaca aactttaaga acagttctga tcaatatgac aaaagctgct
     4741 tttgcagcta agcaaatgtt tttgttctag attaaatatt ctttagaaat gtctcaaact
     4801 taaaggctgc taactattca tagctactat aataagtgtt tactatatga cttagaaact
     4861 ggattttgaa ggaaaaactg taggcgagca atttatatta agtttactta gcattctttt
     4921 tctcaagtaa ttggagatat tccttttaag ttttaagtat aaatagagaa gctagtttag
     4981 tttccttata taaataaaac agctaattta ttaaaatata taaacagcat ttatctttta
     5041 tctgacaatt tttaaatagc ttaaaaagaa acaccaggta gtagaatttt aattatctag
     5101 aagtcaggaa taaccaggaa cctgtagttt tagtctgttc ttttaaaaag ctgaaaacta
     5161 aaactggaaa acttactttg cacaagtata accccagaat ttatttagga ggctgaggca
     5221 agagtctgag attaaagtca acctccaaaa gaccctctca ttcaagaaag gaaatgaatc
     5281 ataaattaat gagaccacct atttgattga caaaaccctc cagagttttt ctaaatctga
     5341 aaattgtaga tcttgtctcc cttaaggaaa tatgtgattt aacatgagtt tttactttct
     5401 aagcttctgc attttacagg tagtcttatg cagaacttgc ctgtactgtc attgcagcag
     5461 actcagctcc cagaattatg atgttgtttg tgttgcaaga ggcaaataat aacacgtagg
     5521 gtgaaggtgt gtgaagaaaa gtcacattgg gggctttctg actagttgag tgagctgtag
     5581 gcctacgtga acctcacagt ctaaaatagt gaataaaagt aacgtcttca tacaataaat
     5641 tgttagaaag cttaa
//
