LOCUS       NM_001370897            3784 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus kinesin family member 28 (Kif28), mRNA.
ACCESSION   NM_001370897
VERSION     NM_001370897.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3784)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC122411.4 and AC113977.16.
            
            On Oct 17, 2022 this sequence version replaced NM_001370897.1.
            
            Sequence Note:.
            
            ##Evidence-Data-START##
            RNAseq introns :: partial sample support SAMN00849374, SAMN00849375
                              [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-144               AC122411.4         64863-65006         c
            145-336             AC122411.4         59674-59865         c
            337-540             AC122411.4         55676-55879         c
            541-576             AC122411.4         54109-54144         c
            577-801             AC113977.16        202368-202592       c
            802-956             AC113977.16        200616-200770       c
            957-1068            AC113977.16        197579-197690       c
            1069-1136           AC113977.16        186082-186149       c
            1137-1243           AC113977.16        183243-183349       c
            1244-1356           AC113977.16        182198-182310       c
            1357-1447           AC113977.16        181822-181912       c
            1448-1502           AC113977.16        180661-180715       c
            1503-1626           AC113977.16        178721-178844       c
            1627-1771           AC113977.16        177767-177911       c
            1772-1890           AC113977.16        175119-175237       c
            1891-1998           AC113977.16        174480-174587       c
            1999-2273           AC113977.16        171752-172026       c
            2274-2408           AC113977.16        169607-169741       c
            2409-2575           AC113977.16        168664-168830       c
            2576-2682           AC113977.16        168349-168455       c
            2683-2830           AC113977.16        167978-168125       c
            2831-3006           AC113977.16        167147-167322       c
            3007-3784           AC113977.16        164407-165184       c
FEATURES             Location/Qualifiers
     source          1..3784
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 83.62 cM"
     gene            1..3784
                     /gene="Kif28"
                     /gene_synonym="Gm1305; Kif28p"
                     /note="kinesin family member 28"
                     /db_xref="GeneID:383592"
                     /db_xref="MGI:MGI:2686151"
     exon            1..144
                     /gene="Kif28"
                     /gene_synonym="Gm1305; Kif28p"
                     /inference="alignment:Splign:2.1.0"
     CDS             61..3162
                     /gene="Kif28"
                     /gene_synonym="Gm1305; Kif28p"
                     /note="kinesin-like protein 6; kinesin-like protein
                     KIF28P"
                     /codon_start=1
                     /product="kinesin-like protein KIF28"
                     /protein_id="NP_001357826.1"
                     /db_xref="GeneID:383592"
                     /db_xref="MGI:MGI:2686151"
                     /translation="MDNEKMGRVPVPRSDSVRVAVRVRPFSQREKNSGSQCVISMHSG
                     NISIRDPKNEERVKTFTFDLTYWSHDGFQKDEDGVLIPSDPASKFAGQSDVFHDIGRG
                     ILDSAWRGYNATLLAYGQTGSGKSYSMIGFGTNKGLIPRVCEELFQAIEKQKENLEPQ
                     VMFSMLEIYNEQIRDLLSRTKAPGGLRVREDQQLGFFVEGLKWVPCENYAQIEKLVEQ
                     GSKIRMTASTNMNASSSRSHMLIAIQFKQVFLDTALTKRSSINMVDLAGSERQRSSGS
                     EGDRLREGSRVNLSLTSLGNVISALADLAMGKKVLHIPYRDSVLTKLLQSALGGNSRT
                     TLIAALSPADICYEETLSTLRYAERAKKVRNRAVINTCPLARASRAENALLLGFRGAG
                     AAEHPACFWAEQQLGNQGTWAQLLEQARREWEEQYEALTQEQKMVRILPHLLNVNEDP
                     QLTGVLKFFIHNGSCDVGRAASNAICLQGLGISDKHASFVNLDGKVTVAPHSKCKVIV
                     NGVPVTGRTKLQHLDRIILGSNSAFLYVGFPSERGAEDLSRFDYDFFQLERAAAEGVS
                     VATLGCVSPGDDQADPSILAVFQDYVKLMPLVVEANQMSEELKKGLTMELKVKNLASS
                     DSRGYDLQKEVMVKVTKQGTHEVWIWSKAKFINRKFLMEELYQRFLESRDSHVAQEDD
                     PFWDPLEVVHLGSAHVWLQPLAHCMMLEEQVEFLNCDGLEEAVLHIRITPCSPEGWAH
                     GEEDMVIDPLELLGKRIDFQTHIVRCLGVKWLKEDGSRGIQMGYKIYDLPNTLYTKPV
                     WKSVNPRIEETVHFAALGASREFLDYLLTNALIVDLWGLQEGCAPLGVSQLDVLLTGE
                     GHIMVDTKTFSSVKDVSQITSNQVPELYQKLLKLEQETELLRDVNRALRGENVFLKAS
                     LENAGSAPQAQKLDNPEGATRTAAREAKQVCAQQASSDAQLARALKVFYQGMGVARGQ
                     LLRLRRCRPPEDDQMLRPFVHQQSQMLKDLEDLLESSLHKLKADVAFIVKKRKEYLLP
                     SQQ"
     exon            145..336
                     /gene="Kif28"
                     /gene_synonym="Gm1305; Kif28p"
                     /inference="alignment:Splign:2.1.0"
     exon            337..540
                     /gene="Kif28"
                     /gene_synonym="Gm1305; Kif28p"
                     /inference="alignment:Splign:2.1.0"
     exon            541..576
                     /gene="Kif28"
                     /gene_synonym="Gm1305; Kif28p"
                     /inference="alignment:Splign:2.1.0"
     exon            577..801
                     /gene="Kif28"
                     /gene_synonym="Gm1305; Kif28p"
                     /inference="alignment:Splign:2.1.0"
     exon            802..956
                     /gene="Kif28"
                     /gene_synonym="Gm1305; Kif28p"
                     /inference="alignment:Splign:2.1.0"
     exon            957..1068
                     /gene="Kif28"
                     /gene_synonym="Gm1305; Kif28p"
                     /inference="alignment:Splign:2.1.0"
     exon            1069..1136
                     /gene="Kif28"
                     /gene_synonym="Gm1305; Kif28p"
                     /inference="alignment:Splign:2.1.0"
     exon            1137..1243
                     /gene="Kif28"
                     /gene_synonym="Gm1305; Kif28p"
                     /inference="alignment:Splign:2.1.0"
     exon            1244..1356
                     /gene="Kif28"
                     /gene_synonym="Gm1305; Kif28p"
                     /inference="alignment:Splign:2.1.0"
     exon            1357..1447
                     /gene="Kif28"
                     /gene_synonym="Gm1305; Kif28p"
                     /inference="alignment:Splign:2.1.0"
     exon            1448..1502
                     /gene="Kif28"
                     /gene_synonym="Gm1305; Kif28p"
                     /inference="alignment:Splign:2.1.0"
     exon            1503..1626
                     /gene="Kif28"
                     /gene_synonym="Gm1305; Kif28p"
                     /inference="alignment:Splign:2.1.0"
     exon            1627..1771
                     /gene="Kif28"
                     /gene_synonym="Gm1305; Kif28p"
                     /inference="alignment:Splign:2.1.0"
     exon            1772..1890
                     /gene="Kif28"
                     /gene_synonym="Gm1305; Kif28p"
                     /inference="alignment:Splign:2.1.0"
     exon            1891..1998
                     /gene="Kif28"
                     /gene_synonym="Gm1305; Kif28p"
                     /inference="alignment:Splign:2.1.0"
     exon            1999..2273
                     /gene="Kif28"
                     /gene_synonym="Gm1305; Kif28p"
                     /inference="alignment:Splign:2.1.0"
     exon            2274..2408
                     /gene="Kif28"
                     /gene_synonym="Gm1305; Kif28p"
                     /inference="alignment:Splign:2.1.0"
     exon            2409..2575
                     /gene="Kif28"
                     /gene_synonym="Gm1305; Kif28p"
                     /inference="alignment:Splign:2.1.0"
     exon            2576..2682
                     /gene="Kif28"
                     /gene_synonym="Gm1305; Kif28p"
                     /inference="alignment:Splign:2.1.0"
     exon            2683..2830
                     /gene="Kif28"
                     /gene_synonym="Gm1305; Kif28p"
                     /inference="alignment:Splign:2.1.0"
     exon            2831..3006
                     /gene="Kif28"
                     /gene_synonym="Gm1305; Kif28p"
                     /inference="alignment:Splign:2.1.0"
     exon            3007..3784
                     /gene="Kif28"
                     /gene_synonym="Gm1305; Kif28p"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3760..3765
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Kif28"
                     /gene_synonym="Gm1305; Kif28p"
                     /note="hexamer: TATAAA"
     polyA_site      3784
                     /gene="Kif28"
                     /gene_synonym="Gm1305; Kif28p"
                     /note="major polyA site"
ORIGIN      
        1 agctttggat gttttcgtga gcagtgtgct ttgtgtgtta tttttctacc gagtagcatc
       61 atggataatg agaaaatggg gagagtgcct gtgccgagat cggacagtgt gagagtggcc
      121 gtccgggtgc ggccgttcag ccagagagaa aagaactctg gaagccagtg tgtgatctcc
      181 atgcattccg gaaacatcag catccgagac cctaagaacg aagagcgtgt gaagaccttt
      241 acctttgacc tgacatattg gtctcacgat ggatttcaaa aggatgaaga tggtgtcctt
      301 attccatctg atccagctag taaatttgca ggccagagcg atgtcttcca tgatatcgga
      361 aggggaattc tagacagtgc ctggcgaggc tacaatgcta ctctcctggc ctatggccag
      421 acgggctctg gaaaaagcta ctccatgatt ggctttggca caaacaaggg tcttattcca
      481 agagtgtgtg aagagctctt ccaagctatt gagaagcaaa aggaaaatct agaaccccag
      541 gttatgttta gcatgctgga aatctacaat gaacagatca gggatttgct gtctagaacc
      601 aaagctcccg gaggcttaag agtcagggag gatcaacagc tggggttttt tgtggaaggt
      661 ctgaagtggg tgccttgtga gaattatgca caaattgaaa agctggtgga gcaaggatca
      721 aaaatcagga tgacagcgtc caccaacatg aacgccagca gcagccgatc ccacatgcta
      781 atcgccatcc agttcaagca ggttttcctg gacacagctc tcaccaaacg gtccagcatc
      841 aacatggtgg acttggcggg aagcgagagg cagaggtcat cagggtctga aggagaccgt
      901 ctgagggaag gatcaagggt caatttaagc ctaaccagtt tagggaacgt catcagtgct
      961 ctggccgacc tagccatggg gaagaaagtt ctgcatattc cctacaggga ttctgttctg
     1021 accaaactgc tccagtcagc cctgggcgga aacagccgga caacactgat tgcagcccta
     1081 agtccagctg acatctgtta tgaggaaacc ttgtcgacac tgagatatgc tgagagggct
     1141 aagaaggttc gcaacagagc ggtgatcaac acctgtccac tggcgagagc ttccagggcc
     1201 gagaacgcac tgctgcttgg attcaggggc gctggagcag cagagcaccc agcctgtttc
     1261 tgggcagaac agcagctggg gaatcagggg acctgggccc agctgctgga gcaggcacgg
     1321 agggagtggg aggagcagta cgaggcactc acacaggagc agaagatggt aaggattctc
     1381 ccgcacctcc tcaatgtcaa tgaagaccca cagctcacgg gggtcctcaa gttcttcatt
     1441 cacaatggct cctgtgatgt tggtcgagct gcctcaaacg ccatctgcct tcaaggcctg
     1501 ggaatttcag ataaacatgc ttccttcgtg aatttggatg gtaaagtgac agtcgcacca
     1561 cacagcaagt gcaaagtcat tgttaatggg gtaccagtca ccggcaggac aaagctgcag
     1621 catttggacc gcatcatcct ggggtccaac agtgccttcc tctatgtcgg atttccctcc
     1681 gagcgaggtg ctgaagacct gagcagattc gactacgact ttttccagct ggagcgggct
     1741 gcagccgagg gcgtgagtgt ggccacgctt ggttgtgtca gccctggaga tgaccaagct
     1801 gaccccagca tcttagctgt gttccaggac tacgtcaaac tcatgccgct ggttgttgaa
     1861 gccaatcaga tgagcgaaga gttgaagaag gggcttacaa tggaattgaa ggtgaagaat
     1921 ttagcatcgt cagattccag gggctatgac ctccaaaaag aggtcatggt gaaggtgacc
     1981 aaacaaggaa ctcacgaggt atggatttgg tcaaaagcca agttcatcaa taggaaattc
     2041 ttgatggagg aactttacca gcgttttcta gagagcagag acagccacgt agctcaggaa
     2101 gatgaccctt tctgggatcc cctggaggtt gttcacttgg gctcagcaca cgtctggctg
     2161 cagcccctgg ctcactgcat gatgctggag gagcaggtgg agtttttgaa ctgtgacggg
     2221 ctggaggagg cagtgctaca cattcgaatc acaccctgct ccccggaagg atgggcacat
     2281 ggtgaggaag acatggttat tgaccctctg gagctgttgg gcaagaggat tgacttccag
     2341 actcacatcg tccggtgcct tggtgtcaaa tggctaaagg aagatggaag ccggggcatt
     2401 cagatggggt acaagattta tgatcttcca aatactttgt acaccaaacc tgtatggaaa
     2461 agtgtgaatc ccagaattga agagactgtc cactttgcag ccttgggtgc atctcgagag
     2521 tttctggatt acttactgac caatgccctc attgtcgatc tgtggggcct ccaagaaggc
     2581 tgtgccccct tgggcgtctc tcagctggat gtcctgctca caggtgaagg ccacatcatg
     2641 gtagacacca agacattttc cagtgtgaag gatgtgagcc agatcacgtc aaaccaggtg
     2701 ccagagcttt atcagaagtt gctcaaatta gagcaggaga cggagctgct gagagatgtt
     2761 aacagggctc tcagaggtga aaatgtgttt ctcaaggctt cactggaaaa cgctggttct
     2821 gctccacagg cccagaagct ggataatcca gaaggagcta caaggacagc tgctagagag
     2881 gctaagcaag tgtgtgctca gcaggccagc tccgatgccc agctggccag agccttgaag
     2941 gtgttctatc aaggcatggg tgtggccaga ggacagctcc tcagactgag gcgatgcaga
     3001 cctcccgaag atgatcaaat gcttcggcca tttgtgcatc agcagtcgca gatgctaaag
     3061 gacttggagg acctgctgga gtccagttta cacaagttaa aagccgacgt tgctttcata
     3121 gtgaagaaga ggaaagagta tctactgccc agccaacagt gaaaatgagc cagctgaaca
     3181 ctgcacacat gctctgactt agtgagcggc acagatgcgt ggaccacgtg cctcttttcc
     3241 agcaaggact tgctgtggac cagaattgct ttagctcatc tctgtacctc cagccccagt
     3301 acagggatca cagacctgag ccaccgccac actgggcctt aactggattt taaaatcctg
     3361 taaaaactgc caggtggtga tggcacatgc ctttaatccc agcacgtggg aggcagagac
     3421 aggtggatct ctatgagtgc agggccagcc tggtctacag agtgacttct aggacagcca
     3481 ggactacaca gagaagatct cacttgaaaa aagaaaaaaa aaaaaaaaaa aaagaaagaa
     3541 atcctataaa aaatgaacag atatgcagga tgtctggtga atgttgagaa cctagagctc
     3601 tggatgtgac tgcccaagat tcagtcctgg ctaaatctat cacttacaaa ttgtacgggg
     3661 tgttgggggg actcagccac cctctctaag cctctttcct tgtgagttat ctgtgatgga
     3721 caatcattac caacctcctg gaaggctttt ttggtccttt ataaaagatt aattttatta
     3781 tgta
//
