LOCUS       NM_001161665            7422 bp    mRNA    linear   ROD 09-FEB-2025
DEFINITION  Mus musculus kinesin family member 26B (Kif26b), mRNA.
ACCESSION   NM_001161665
VERSION     NM_001161665.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 7422)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 7422)
  AUTHORS   Yamamura,Y., Iwata,Y., Furuichi,K., Kato,T., Yamamoto,N.,
            Horikoshi,K., Ogura,H., Sato,K., Oshima,M., Nakagawa,S.,
            Miyagawa,T., Kitajima,S., Toyama,T., Hara,A., Sakai,N., Shimizu,M.,
            Horike,S., Daikoku,T., Nishinakamura,R. and Wada,T.
  TITLE     Kif26b contributes to the progression of interstitial fibrosis via
            migration and myofibroblast differentiation in renal fibroblast
  JOURNAL   FASEB J 36 (11), e22606 (2022)
   PUBMED   36250931
  REMARK    GeneRIF: Kif26b contributes to the progression of interstitial
            fibrosis via migration and myofibroblast differentiation in renal
            fibroblast.
REFERENCE   3  (bases 1 to 7422)
  AUTHORS   Yan,M., Cai,L., Duan,X. and Rai,M.F.
  TITLE     Novel mechanistic role of Kif26b in adipogenic differentiation of
            murine multipotent stromal cells
  JOURNAL   Biochem Biophys Res Commun 592, 125-133 (2022)
   PUBMED   35066304
  REMARK    GeneRIF: Novel mechanistic role of Kif26b in adipogenic
            differentiation of murine multipotent stromal cells.
REFERENCE   4  (bases 1 to 7422)
  AUTHORS   Yan,M., Duan,X., Cai,L., Zhang,W., Silva,M.J., Brophy,R.H. and
            Rai,M.F.
  TITLE     KIF26B Silencing Prevents Osseous Transdifferentiation of
            Progenitor/Stem Cells and Attenuates Ectopic Calcification in a
            Murine Model
  JOURNAL   J Bone Miner Res 37 (2), 349-368 (2022)
   PUBMED   34787331
  REMARK    GeneRIF: KIF26B Silencing Prevents Osseous Transdifferentiation of
            Progenitor/Stem Cells and Attenuates Ectopic Calcification in a
            Murine Model.
REFERENCE   5  (bases 1 to 7422)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 7422)
  AUTHORS   Heinrich,J., Proepper,C., Schmidt,T., Linta,L., Liebau,S. and
            Boeckers,T.M.
  TITLE     The postsynaptic density protein Abelson interactor protein 1
            interacts with the motor protein Kinesin family member 26B in
            hippocampal neurons
  JOURNAL   Neuroscience 221, 86-95 (2012)
   PUBMED   22766233
REFERENCE   7  (bases 1 to 7422)
  AUTHORS   Kim,B.M., Thier,M.C., Oh,S., Sherwood,R., Kanellopoulou,C.,
            Edenhofer,F. and Choi,M.Y.
  TITLE     MicroRNAs are indispensable for reprogramming mouse embryonic
            fibroblasts into induced stem cell-like cells
  JOURNAL   PLoS One 7 (6), e39239 (2012)
   PUBMED   22737231
REFERENCE   8  (bases 1 to 7422)
  AUTHORS   Uchiyama,Y., Sakaguchi,M., Terabayashi,T., Inenaga,T., Inoue,S.,
            Kobayashi,C., Oshima,N., Kiyonari,H., Nakagata,N., Sato,Y.,
            Sekiguchi,K., Miki,H., Araki,E., Fujimura,S., Tanaka,S.S. and
            Nishinakamura,R.
  TITLE     Kif26b, a kinesin family gene, regulates adhesion of the embryonic
            kidney mesenchyme
  JOURNAL   Proc Natl Acad Sci U S A 107 (20), 9240-9245 (2010)
   PUBMED   20439720
  REMARK    GeneRIF: Kif26b, a kinesin family gene, regulates adhesion of the
            embryonic kidney mesenchyme.
REFERENCE   9  (bases 1 to 7422)
  AUTHORS   Marikawa,Y., Fujita,T.C. and Alarcon,V.B.
  TITLE     An enhancer-trap LacZ transgene reveals a distinct expression
            pattern of Kinesin family 26B in mouse embryos
  JOURNAL   Dev Genes Evol 214 (2), 64-71 (2004)
   PUBMED   14727108
  REMARK    GeneRIF: KIF26B may play a role in embryogenesis, specifically in
            the development of limbs, face, and somites
REFERENCE   10 (bases 1 to 7422)
  AUTHORS   Miki,H., Setou,M., Kaneshiro,K. and Hirokawa,N.
  TITLE     All kinesin superfamily protein, KIF, genes in mouse and human
  JOURNAL   Proc Natl Acad Sci U S A 98 (13), 7004-7011 (2001)
   PUBMED   11416179
  REMARK    Review article
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK052046.1, AC140776.6, BC068141.1 and CD348243.1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data because no single mouse transcript was
            available for the full length of the gene. The full-length splice
            pattern of this transcript record is supported by orthologous
            transcript alignments from human.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB355846.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849382
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1216              AK052046.1         2-1217
            1217-1370           AC140776.6         127614-127767
            1371-1604           AK052046.1         1372-1605
            1605-7404           BC068141.1         417-6216
            7405-7422           CD348243.1         527-544
FEATURES             Location/Qualifiers
     source          1..7422
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 83.16 cM"
     gene            1..7422
                     /gene="Kif26b"
                     /gene_synonym="4832420M10; D230039L06Rik"
                     /note="kinesin family member 26B"
                     /db_xref="GeneID:269152"
                     /db_xref="MGI:MGI:2447076"
     exon            1..501
                     /gene="Kif26b"
                     /gene_synonym="4832420M10; D230039L06Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             439..6777
                     /gene="Kif26b"
                     /gene_synonym="4832420M10; D230039L06Rik"
                     /note="kinesin family protein 26b; N-11 kinesin"
                     /codon_start=1
                     /product="kinesin-like protein KIF26B"
                     /protein_id="NP_001155137.1"
                     /db_xref="CCDS:CCDS48464.1"
                     /db_xref="GeneID:269152"
                     /db_xref="MGI:MGI:2447076"
                     /translation="MNSVAGNKERLAVSTRGKKYGVNEMCSPTKPSAPCSPESWYRKA
                     YEESRAGSRPTPEGAGSALGSSGTPSPGSGTSSPSSFTGSPGPASPGIGTSSPGSLGG
                     SPGFGTGSPGSGSGGGSSPGSDRGVWCENCNARLVELKRQALKLLLPGPLPGKDPAFS
                     AVIHDKLQVPNTIRKSWNDRDNRCDICATHLNQLKQEAIQMVLTLEQAAGSEHYDTSL
                     GSPPPISSIPTLVGSRHMGGLQQPREWAFVPAPYATSTYTGLVNKHSGKPNSLGVSNG
                     AEKKSGSPTHQAKVSLQMATSPSNGNILNSVAIQAHQYLDGTWSLSRTNGVTLYPYQI
                     SQLMTETGREGLTESALNRYNADKPAASSVPAPQGSCVASETSTGTSVAASFFARAAQ
                     KLNLSSKKKKHRPSTPSVAEAPLFATSFSGILQTSPPPAPPCLLRAVNKVKDTPGMGK
                     VKVMLRICSTSARDTSESSSFLKVDPRKKQITLYDPLTCGGQNAFQKRSSQVPPKMFA
                     FDAVFPQDASQAEVCAGTVAEVIQSVVNGADGCVFCFGHAKLGKSYTMIGRDDSMQNL
                     GIIPCAISWLFKLINERKEKTGARFSVRISAVEVWGKEENLRDLLSEVATGSLQDGQS
                     PGVYLCEDPICGTQLQNQSELRAPTAEKAAFFLDAAIASRRSNQQDCDEDDHRNSHML
                     FTLHIYQYRMEKSGKGGMSGGRSRLHLIDLGSCVKALSKNREGGSGLCLSLSALGNVI
                     LALVNGSKHIPYKESKLTMLLRESLGNVNCRTTMIAHISAAASSYAETLSTIQIASRV
                     LRMKKKKTKYTSSSSGGESSCEEGRMRRPTQLRPFHARAPVDPEFPLAPLSSDPDYSS
                     SSEQSCDTVIYIGPNGTALSDKELTDNEGPPDFVPIVPALQKTRGDSRPGEAAEAAAS
                     KSERDCLKCNTFAELQERLDCIDGSEEPSKFPFEELPIQFGPEQAGRCAPLSQAVGPD
                     TPSESEKEDNGSDNGQLTEREGTELPASKAQRNRSPAPTVTRSSSPSPASPRSIPGSS
                     SQHSTSQLTQSPSLQSSRESLNSCGFVEGKPRPMGSPRLGIASLSKTSEYKPPSSPSQ
                     RCKVYTQKGVLPSSAPPPSLSKDSGMVSSESLLQPDVRTPPVGMSPQVLKKSMSAGSE
                     GFPGTLVDGEDQEGPPADSKKEILSTTMVTVQQPLELNGEDELVFTLVEELTISGVLD
                     SGRPTSIISFNSDCSVQALASGSRPVSIISSISEDLECYSSMAPVSEVSITQFLPLPK
                     LGLDEKARDAGSRRSSISSWLSEMSAGSDGEQSCHSFIAQTCFGHGEAMAEPPASEFV
                     SSIQNTAVVCREKPEVGPDNLLILSEMGEESGNKAAPIKGCKISTVGKAMVTISNTAS
                     LSSCEGYIPMKTNITVYPCIAMSPRNVQEPESSTATPKVSPKASQAQESKEPSTRREM
                     KFEDPWLKREEEVKRENAYSSEEGVKCEPLPSSLKTEGKSEQELDGRPSSGNRLSSSS
                     SEAAAFQGTDNVRRVVDGCEMALPGLVAQSPLHVNRNLKSSSLPRAFQKADRHEELDS
                     FYHCLADSNGFSAASGIPSSKTTLERKVASPKHCVLARPKGTPPLPPVRKSSLDQKNR
                     ASPQHGGGSSNTSSPLNQPATFLACFPDESNGKTKDVSSSSKLFSAKLEQLASRSNSL
                     GRTTVSHYECLSLERAESLSSVSSRMHAGKDSTMPRTGRSLGRSTGASPPSCGITQST
                     GASPKASQSKISAVSKLLLASPKSRSSLSTSTTKTLSFSTKSLPQSVGQSSNLPPSGK
                     HMSWSTQSLSRNRGSGLASKLPLRAVNGRISELLQGSAGPRSAQLRAEAEERSGAPSE
                     DKPAAAHLLPSPYSKITPPRKPHRCSSGHGSDNSSVLSGELPPAMGKTALFYHSGGSS
                     GYESMMRDSEATGSASSAQDSMSENSSSVGGRCRSLKNQKKRSNSGSQRRRLIPALSL
                     DTPSPVRKTASSTGVRWVDGPLRSTQRSLGEPFEIKVYEIDDVERLQRRRGATSKEVM
                     CFNAKLKILEHRQQRIAEVRAKYEWLMKELEATKQYLMLDPNKWLREFDLEQVLQLDS
                     LEYLEALEGVTERLESRVNFCKAHLMMITCFDITSRRR"
     exon            502..903
                     /gene="Kif26b"
                     /gene_synonym="4832420M10; D230039L06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            904..1437
                     /gene="Kif26b"
                     /gene_synonym="4832420M10; D230039L06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1438..1604
                     /gene="Kif26b"
                     /gene_synonym="4832420M10; D230039L06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1605..1788
                     /gene="Kif26b"
                     /gene_synonym="4832420M10; D230039L06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1789..1995
                     /gene="Kif26b"
                     /gene_synonym="4832420M10; D230039L06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1996..2089
                     /gene="Kif26b"
                     /gene_synonym="4832420M10; D230039L06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2090..2352
                     /gene="Kif26b"
                     /gene_synonym="4832420M10; D230039L06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2353..2536
                     /gene="Kif26b"
                     /gene_synonym="4832420M10; D230039L06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2537..2696
                     /gene="Kif26b"
                     /gene_synonym="4832420M10; D230039L06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2697..2859
                     /gene="Kif26b"
                     /gene_synonym="4832420M10; D230039L06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2860..6274
                     /gene="Kif26b"
                     /gene_synonym="4832420M10; D230039L06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            6275..6477
                     /gene="Kif26b"
                     /gene_synonym="4832420M10; D230039L06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            6478..6628
                     /gene="Kif26b"
                     /gene_synonym="4832420M10; D230039L06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            6629..7406
                     /gene="Kif26b"
                     /gene_synonym="4832420M10; D230039L06Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      7385..7390
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Kif26b"
                     /gene_synonym="4832420M10; D230039L06Rik"
                     /note="hexamer: AATAAA"
     polyA_site      7401
                     /gene="Kif26b"
                     /gene_synonym="4832420M10; D230039L06Rik"
                     /note="major polyA site"
ORIGIN      
        1 agttagcgag ctcggggaag gaggcaagtt cccaccgccg gctcggctcg gcgagggctc
       61 gcccaccttc cctgcagcct ccctgcgtcc tcgccgccgt cctcctccgt ttcggccccg
      121 ctagaggaga acgcgcgctg gccgggtgga ggaaaatgct agcgatctgg atgtgaccgc
      181 gaagagagga cgcgtggctg gaggaggcag agagatgaga agacccatta tttgagaacc
      241 accagccgtt ccaacctttc ctgcaaattg gtgctattac ttctggggtc catttgcttt
      301 cattcttccc aaccccccat taagaaatct tgacttgagg accaacccct accacgaggg
      361 gggacgcgtc tgggttggca gaccttttgg atgtagcctt gtgggaacat ttagaccctt
      421 tcctctggaa gagccaccat gaattcggta gccggaaata aagagaggct tgcggtctcc
      481 accaggggca agaaatacgg ggtgaacgaa atgtgctcgc ccaccaagcc ctcagcgccc
      541 tgctctcctg agagctggta ccgcaaggct tacgaggagt cgcgcgccgg cagccggccc
      601 accccggagg gagcaggctc tgcgctgggc tcatcgggca ccccgtcccc gggctcgggc
      661 acctcgtccc cgagctcctt caccggctct ccgggacctg catctccggg cattggtacc
      721 agctcgcccg gctctctggg cggctcaccc ggcttcggca ccggctcccc tggctcgggc
      781 agcggcggcg gctcctcccc cggctccgac cgcggcgtct ggtgcgagaa ctgtaacgcc
      841 cgcttggtgg agctgaagag gcaggctctc aagctgctgc tgccgggacc cctcccggga
      901 aaggaccctg ctttctctgc tgtgattcac gacaaactcc aggttcccaa tactatcagg
      961 aagtcgtgga atgaccgaga caaccgctgt gacatttgtg ccacacacct gaaccagcta
     1021 aagcaggaag ccatccaaat ggtgctgacc ttggagcagg cagctggcag cgagcactat
     1081 gacacctctc tgggctcacc ccctccgatc tccagcattc ccacactggt ggggtctcgc
     1141 cacatgggtg ggctccagca gcccagggag tgggcctttg tgcctgcccc ctatgccact
     1201 tctacctaca caggccttgt caacaaacac agcggcaaac ccaacagcct tggggtcagc
     1261 aacggagcgg aaaagaagag tggctcccca acccaccagg ccaaggtcag cctccagatg
     1321 gccaccagtc ccagcaatgg aaacatcctc aactcggtgg ccattcaggc tcatcaatat
     1381 ctagacggca cctggtccct ttcaagaacc aatggggtta ccctgtaccc ctaccagatc
     1441 tcccagctga tgacagagac cggccgcgag ggactgacag agtcagcgct caaccgctac
     1501 aatgctgaca agcctgcagc cagcagtgtc ccagccccac agggttcctg tgtggccagt
     1561 gagacttcca cagggacctc agtggccgct tccttcttcg cacgagctgc ccagaagtta
     1621 aatctgtcat ctaagaagaa gaaacaccgg ccttcgactc catctgttgc ggaggctccc
     1681 ctctttgcga ccagcttcag tgggatcctg cagacctctc ctcccccagc cccaccctgt
     1741 ctcctgaggg ctgtcaacaa ggtgaaggac actcctggca tgggcaaggt gaaagtcatg
     1801 ctgcgtatct gttccacatc agctcgagat acctcagaat ccagctcttt cctgaaggtg
     1861 gacccacgga agaagcagat caccttgtat gatcccctga cttgcggagg tcaaaatgcc
     1921 ttccagaaaa gaagcagcca ggttcctccg aagatgtttg ccttcgatgc tgttttccca
     1981 caagatgctt ctcaggctga agtttgtgct ggaactgtgg ccgaagtcat ccagtctgtg
     2041 gtgaacgggg cagatggctg tgtgttctgt tttggccatg ccaagctagg gaaatcctac
     2101 accatgatcg gaagggacga ctctatgcag aacctgggca ttattccatg tgctatttct
     2161 tggctgttca agcttatcaa tgagcgcaaa gagaagacgg gggcccgatt ctcagtccgc
     2221 atctcagccg ttgaggtgtg gggaaaagag gagaaccttc gagacctgtt gtctgaggtg
     2281 gccacgggca gcctacagga cgggcagtcc ccaggcgtgt acctctgtga agaccccatc
     2341 tgtggcacac agctgcagaa ccagagtgag ctccgggccc ccaccgcaga gaaagctgcc
     2401 ttcttcctgg acgccgccat tgcctcgagg cgaagcaacc aacaggattg tgacgaggat
     2461 gaccaccgca actcccatat gctcttcacc ctgcacatct accagtaccg gatggagaag
     2521 agcgggaagg gtggaatgtc tggaggtcga agccgcctgc atctcatcga cctcgggagc
     2581 tgtgtgaaag ctctcagcaa aaaccgagaa ggaggctcgg ggctgtgcct ctcactgtct
     2641 gctctgggca acgtcatcct ggctttggtc aacgggagca agcacatccc atacaaggag
     2701 agcaagctca ccatgcttct gagggagtct ctggggaatg tgaactgtcg caccaccatg
     2761 atcgcacaca tctcggccgc agccagcagc tacgcggaga ccctgtccac catccagatc
     2821 gcgtcgagag tcttaaggat gaagaagaag aagaccaagt acacatcaag ctcctctggg
     2881 ggagaaagct cctgtgagga aggcagaatg cgcaggccca cccagctgag acccttccat
     2941 gcccgggctc cggtggatcc agaattcccc cttgccccac tgtccagtga tcctgactac
     3001 tcctccagca gtgagcagtc ctgcgacacc gtcatctaca tcgggcccaa tggcacagcc
     3061 ctgtctgaca aggaactcac tgacaatgag gggcccccag actttgtgcc cattgtgcca
     3121 gccctacaga agaccagagg tgacagccgg ccgggggagg cagcagaggc tgcagccagc
     3181 aagtcagaaa gggactgtct gaagtgcaat acgtttgctg agctgcagga aagactagat
     3241 tgcatagatg gcagcgaaga acccagtaag tttcccttcg aagagctgcc catccagttc
     3301 gggccggagc aagctggcag atgtgctcct ttaagccaag cagtggggcc agacacaccc
     3361 tctgagtctg aaaaggaaga taacggctca gacaatggcc aattgaccga gagggaaggc
     3421 acagagcttc cagcctccaa ggcacagcgg aatcggtccc ctgcccctac tgtgacacgc
     3481 agcagcagcc ccagtccagc ctcaccacgg agcatcccgg gcagcagtag ccagcacagt
     3541 acctcccagc tcacacagag ccccagtctc cagagcagcc gggagagtct gaactcatgt
     3601 ggcttcgtgg agggcaagcc cagacccatg ggctccccga ggctaggcat tgccagtctg
     3661 tccaagacct cagagtacaa acctcccagt tctccctctc agaggtgcaa agtctacacc
     3721 cagaaggggg tcctgccctc ctctgcccca ccaccttccc tgagcaagga ctctggcatg
     3781 gtctccagtg aatccttgct tcagcccgac gtgcgcactc ccccagttgg aatgagtccc
     3841 caggttttga agaaatccat gtctgccggg agcgaagggt ttcccggaac tctagttgac
     3901 ggtgaggacc aggaaggccc tccagcggac tctaagaagg agattctgag caccacaatg
     3961 gtgactgtgc aacagcccct ggagctgaat ggtgaggatg agttggtctt cacactggtg
     4021 gaggagctga ccatcagcgg ggtgctcgac agtggacgcc ctaccagcat catcagcttc
     4081 aacagtgact gctccgtgca ggccctggcc tcaggctccc ggcccgtcag catcatcagc
     4141 agcatcagcg aggatctgga gtgctactcc agcatggccc ccgtctccga ggtgagcatc
     4201 acgcagttcc tgcctctccc aaagctgggc ctggatgaga aggctcggga cgcgggcagc
     4261 cggcgttcct ccatcagctc ctggctgagc gagatgagcg cgggcagtga tggcgagcag
     4321 tcatgccaca gcttcatagc ccagacgtgc tttgggcatg gggaagccat ggcagaaccc
     4381 ccagcctcgg agtttgtcag cagcatccag aacacggcag tggtgtgcag agagaagccc
     4441 gaggtgggcc ctgacaacct gctcatctta tctgagatgg gggaagagtc tggcaacaaa
     4501 gccgctccca tcaaaggctg caaaatctca acggtgggca aggccatggt caccatctcc
     4561 aacacagcca gcctgagcag ctgcgaaggg tacatcccca tgaagaccaa catcaccgtt
     4621 tacccctgca tcgccatgag cccccgaaac gtgcaagagc ctgagtcctc cactgccacc
     4681 ccaaaggtga gccccaaagc atcccaggcc caggaaagca aggaacccag tacaaggaga
     4741 gagatgaaat ttgaggatcc ttggcttaaa cgagaagaag aggtgaaaag ggagaacgct
     4801 tactccagcg aggaaggggt taagtgtgag ccgctcccaa gctccctgaa gactgaaggt
     4861 aagtcagagc aggaactgga tggcaggccc agctcaggca acaggctgag cagcagcagc
     4921 tcagaggcag ccgcctttca agggactgat aacgttagga gagtcgtgga tggctgtgag
     4981 atggccctgc ctggcttggt ggcccaaagt cccctccatg tcaaccgaaa cctaaagtca
     5041 agcagcctcc caagggcatt tcagaaagct gacaggcacg aggagctgga cagcttctac
     5101 cattgcctgg cagacagcaa tggcttcagt gctgcttcgg gcatcccatc ctcgaagaca
     5161 accctagaga ggaaagttgc ttcacccaag cattgcgtcc tggcaaggcc caaagggacc
     5221 ccgcctctgc ctcctgtccg caagtctagc ttggaccaga agaacagggc cagccctcaa
     5281 cacggtggtg gcagcagcaa caccagcagc cccctgaacc agccagctac cttcttggct
     5341 tgcttccctg atgagtccaa cggcaagact aaggatgtca gtagcagcag taagctcttc
     5401 agcgccaagc tggaacagct ggccagcaga agcaactctc ttggcaggac aacagtcagc
     5461 cactacgaat gcttgtcgtt ggagagggcc gaaagcctgt cgtcggtgag ctcccgcatg
     5521 catgccggca aagatagtac catgccccgc actgggagga gcctgggtcg cagcactggc
     5581 gcctcaccac ccagctgtgg catcactcag tccacagggg cctctcccaa ggccagccag
     5641 tctaagatct ctgcagtgag caagctcctg ctggccagtc ctaaatcccg cagcagcctg
     5701 tccacctcca ccaccaaaac cctcagcttc tccaccaagt ccctgccaca gtctgtgggc
     5761 cagagctcca acctaccgcc cagcgggaaa cacatgtcct ggtccaccca gtcgctcagc
     5821 aggaaccggg gctctgggct ggcttccaaa ctgccgctaa gagcggtcaa cgggcgcatt
     5881 tcggagctgc tccagggcag tgcgggcccg aggagtgcac agctgcgggc agaggcggaa
     5941 gagcgcagtg gggctccctc ggaggacaag cccgcagccg cccacctgct gccctcgccc
     6001 tacagcaaga tcacccctcc gaggaagccg caccgctgca gcagcgggca cggtagtgat
     6061 aacagcagtg tcctgagtgg ggagctacca cctgccatgg ggaagactgc cctcttctac
     6121 cacagcggag gcagcagtgg ctacgagagc atgatgagag acagcgaggc caccggcagt
     6181 gcatcctcag cccaggactc catgagcgag aacagcagct ccgtgggagg gagatgcagg
     6241 agcctcaaaa accaaaagaa aaggtccaat tcaggttccc agagacggag gctcattcca
     6301 gcactgtctc tcgatacccc ctcacctgtg aggaaaactg ccagcagcac aggggtccgc
     6361 tgggtggacg gccccttgag gagcacccag aggagccttg gggaaccatt cgaaattaaa
     6421 gtctatgaga ttgatgacgt ggagcgcctg cagcgacgtc gaggagctac aagcaaggag
     6481 gtcatgtgct tcaatgccaa gctgaaaatc ctagaacatc ggcagcagag aatcgctgaa
     6541 gtccgagcca agtacgagtg gctgatgaag gagctagaag cgaccaagca gtacctgatg
     6601 ctggacccca acaagtggct tcgtgaattt gacttggagc aggtcctgca gctggattcc
     6661 ctggagtacc tggaggcact ggagggtgtg acagagcgct tggagagccg cgtcaacttc
     6721 tgcaaggccc atctcatgat gatcacctgc tttgacatca cctccaggcg ccgataagga
     6781 ctgatgggct ctgagccatc aggccctctc tcccccagga cttcagcagg acaccgccct
     6841 cccaagccct ctgtgctggc aacacccaag acaacaggat gaggatgaag gttggtagca
     6901 agtctggagt gagcgtggag cgaaaggcga tgtttccttt gtttgccata ggaaagaaag
     6961 gtacagacac caacatgtgg aaggaggaaa tgatgggaag ccccgtggga ctgagaaagc
     7021 actttgagga accttgaaga actctgtaca taggaccgct agcaaagaga ctcttacctt
     7081 gcggctgtgg gaaaggggag ggtgacatgg gattaccatg gagaacgaaa caccaacaag
     7141 atgacccaga atgatggatt aagtgccttg caaatcttta tgattatcca aacattgtgt
     7201 ccgtactttc ttgtgtccag atggtgctag tcaagaagaa atcaacaaaa cagaaaactc
     7261 aacccagttt ttgaaatgta ttgacggctt gttttctctt ggtatttttc tcttgtttct
     7321 gatttgctgt ttgtttctaa gaagttgtgt ttgtagtgat gtctcctaat cggtattgca
     7381 gctgaataaa tgttaactgt ctttcaaaaa aaaaaaaaaa aa
//
