LOCUS       NM_001097621            6918 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus kinesin family member 26A (Kif26a), mRNA.
ACCESSION   NM_001097621 XM_001477486 XM_001477732
VERSION     NM_001097621.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6918)
  AUTHORS   Almannai,M., AlAbdi,L., Maddirevula,S., Alotaibi,M., Alsaleem,B.M.,
            Aljadhai,Y.I., Alsaif,H.S., Abukhalid,M. and Alkuraya,F.S.
  TITLE     KIF26A is mutated in the syndrome of congenital hydrocephalus with
            megacolon
  JOURNAL   Hum Genet 142 (3), 399-405 (2023)
   PUBMED   36564622
  REMARK    GeneRIF: KIF26A is mutated in the syndrome of congenital
            hydrocephalus with megacolon.
REFERENCE   2  (bases 1 to 6918)
  AUTHORS   Qian,X., DeGennaro,E.M., Talukdar,M., Akula,S.K., Lai,A.,
            Shao,D.D., Gonzalez,D., Marciano,J.H., Smith,R.S., Hylton,N.K.,
            Yang,E., Bazan,J.F., Barrett,L., Yeh,R.C., Hill,R.S., Beck,S.G.,
            Otani,A., Angad,J., Mitani,T., Posey,J.E., Pehlivan,D., Calame,D.,
            Aydin,H., Yesilbas,O., Parks,K.C., Argilli,E., England,E., Im,K.,
            Taranath,A., Scott,H.S., Barnett,C.P., Arts,P., Sherr,E.H.,
            Lupski,J.R. and Walsh,C.A.
  TITLE     Loss of non-motor kinesin KIF26A causes congenital brain
            malformations via dysregulated neuronal migration and axonal growth
            as well as apoptosis
  JOURNAL   Dev Cell 57 (20), 2381-2396 (2022)
   PUBMED   36228617
  REMARK    GeneRIF: Loss of non-motor kinesin KIF26A causes congenital brain
            malformations via dysregulated neuronal migration and axonal growth
            as well as apoptosis.
REFERENCE   3  (bases 1 to 6918)
  AUTHORS   Tsyporin,J., Tastad,D., Ma,X., Nehme,A., Finn,T., Huebner,L.,
            Liu,G., Gallardo,D., Makhamreh,A., Roberts,J.M., Katzman,S.,
            Sestan,N., McConnell,S.K., Yang,Z., Qiu,S. and Chen,B.
  TITLE     Transcriptional repression by FEZF2 restricts alternative
            identities of cortical projection neurons
  JOURNAL   Cell Rep 35 (12), 109269 (2021)
   PUBMED   34161768
REFERENCE   4  (bases 1 to 6918)
  AUTHORS   Ohara,Y., Fujimura,L., Sakamoto,A., Teratake,Y., Hiraoka,S.,
            Koseki,H., Saito,T., Terui,K., Mitsunaga,T., Nakata,M., Yoshida,H.
            and Hatano,M.
  TITLE     Genetic background-dependent abnormalities of the enteric nervous
            system and intestinal function in Kif26a-deficient mice
  JOURNAL   Sci Rep 11 (1), 3191 (2021)
   PUBMED   33542431
  REMARK    GeneRIF: Genetic background-dependent abnormalities of the enteric
            nervous system and intestinal function in Kif26a-deficient mice.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 6918)
  AUTHORS   Wang,L., Tanaka,Y., Wang,D., Morikawa,M., Zhou,R., Homma,N.,
            Miyamoto,Y. and Hirokawa,N.
  TITLE     The Atypical Kinesin KIF26A Facilitates Termination of Nociceptive
            Responses by Sequestering Focal Adhesion Kinase
  JOURNAL   Cell Rep 24 (11), 2894-2907 (2018)
   PUBMED   30208315
REFERENCE   6  (bases 1 to 6918)
  AUTHORS   Lodato,S., Molyneaux,B.J., Zuccaro,E., Goff,L.A., Chen,H.H.,
            Yuan,W., Meleski,A., Takahashi,E., Mahony,S., Rinn,J.L.,
            Gifford,D.K. and Arlotta,P.
  TITLE     Gene co-regulation by Fezf2 selects neurotransmitter identity and
            connectivity of corticospinal neurons
  JOURNAL   Nat Neurosci 17 (8), 1046-1054 (2014)
   PUBMED   24997765
REFERENCE   7  (bases 1 to 6918)
  AUTHORS   Tripathi,P., Wang,Y., Casey,A.M. and Chen,F.
  TITLE     Absence of canonical Smad signaling in ureteral and bladder
            mesenchyme causes ureteropelvic junction obstruction
  JOURNAL   J Am Soc Nephrol 23 (4), 618-628 (2012)
   PUBMED   22282597
REFERENCE   8  (bases 1 to 6918)
  AUTHORS   Zhou,R., Niwa,S., Homma,N., Takei,Y. and Hirokawa,N.
  TITLE     KIF26A is an unconventional kinesin and regulates GDNF-Ret
            signaling in enteric neuronal development
  JOURNAL   Cell 139 (4), 802-813 (2009)
   PUBMED   19914172
  REMARK    GeneRIF: Mice with a homozygous deletion of Kif26a developed a
            megacolon with enteric nerve hyperplasia. Kif26a-/- enteric neurons
            showed hypersensitivity for GDNF-Ret signaling
REFERENCE   9  (bases 1 to 6918)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Koseki,H., Hiraoka,S.,
            Saga,Y., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: III. the complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (4), 167-180 (2003)
   PUBMED   14621295
REFERENCE   10 (bases 1 to 6918)
  AUTHORS   Miki,H., Setou,M., Kaneshiro,K. and Hirokawa,N.
  TITLE     All kinesin superfamily protein, KIF, genes in mouse and human
  JOURNAL   Proc Natl Acad Sci U S A 98 (13), 7004-7011 (2001)
   PUBMED   11416179
  REMARK    Review article
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CJ130134.1, CD352284.1, CD348409.1, CB520233.1, CD350871.1,
            CB518589.1, BC094358.1, BM963109.1 and BC059062.1.
            
            On or before Jul 25, 2007 this sequence version replaced
            XM_001477486.1, XM_001477732.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: GQ489027.1, SRR10223969.12241.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-424               CJ130134.1         2-425
            425-873             CD352284.1         273-721
            874-1477            CD348409.1         99-702
            1478-1918           CB520233.1         240-680
            1919-2208           CD350871.1         427-716
            2209-2689           CB518589.1         203-683
            2690-3510           BC094358.1         195-1015
            3511-3849           BM963109.1         212-550
            3850-6494           BC094358.1         1355-3999
            6495-6918           BC059062.1         3327-3750
FEATURES             Location/Qualifiers
     source          1..6918
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="12"
                     /map="12 61.14 cM"
     gene            1..6918
                     /gene="Kif26a"
                     /gene_synonym="mKIAA1236"
                     /note="kinesin family member 26A"
                     /db_xref="GeneID:668303"
                     /db_xref="MGI:MGI:2447072"
     exon            1..199
                     /gene="Kif26a"
                     /gene_synonym="mKIAA1236"
                     /inference="alignment:Splign:2.1.0"
     CDS             158..5803
                     /gene="Kif26a"
                     /gene_synonym="mKIAA1236"
                     /note="N-11 kinesin"
                     /codon_start=1
                     /product="kinesin-like protein KIF26A"
                     /protein_id="NP_001091090.1"
                     /db_xref="CCDS:CCDS49186.1"
                     /db_xref="GeneID:668303"
                     /db_xref="MGI:MGI:2447072"
                     /translation="MVGRGASLCAVQPAVAECGPARETPPLEVSPRKRLPAGLDQDPC
                     SSRPAPEGAGASAEQSHSAGGGGWCRHCHTKLVELKRQAWKLVSGPGTPLRDPCLSTL
                     LLDKLPASGVQPACRPDTESRCDVCTTHLHQLTREALRLLQTPASHEDPNASRGGLAA
                     PSSRDPPGPVGLMGRQPPVGPDRRKATAWPPGPSVQVSVAPAGLGGALSTVTIQAQQC
                     LEGVWSLSRVNSFLPPTCLAEAAVAAVAVADTVRDCAPAAGPERMSKAWGRGAACTTA
                     LVTPAPGTSAGGSTGPSAAASFFIRAAQKLSLASKRKKHHPPPAPSTRGTSTYPTDFS
                     GSLQLWPPPVPPCLLRAASKAKENPSSFGKVKVMLRIWPAQGVQRSAESTSFLKVDSR
                     KKQVTLYDPAAGPPGCAGLRHAPTAPVPKMFAFDAIFPQDSEQAEVCSGTVADVLQSV
                     VSGADGCIFSFGHMSLGKSYTMIGKDSSPQSLGIVPCAISWLFRLIDERKERLGTRFS
                     IRVSAVEVCGHDQSLRDLLAEVASGSLQDTQSPGVYLREDPVCGTQLQNQNELRAPTA
                     EKAAFYLDAALAARSTSRAGCGEEARRSSHMLFTLHVYQYRVEKCGQGGMSGGRSRLH
                     LIDLGSCDAAVGRGGEASGGPLCLSLSALGSVILALVNGAKHVPYRDHRLTMLLRESL
                     ATTNCRTTMIAHISDSPAHHAETLSTVQLAARIHRLRRKKGKHASSSSGGESSCEEGR
                     ARRPPHLRPFHPRAVVLDPDRSAPGLSGDPDYSSSSEQSCDTVIYVGPGGMALSDREL
                     TDNEGPPDFVPIIPALSRRRPSEGPRDADHFRCSTFAELQERLECIDGSEAFPGPQGG
                     SDGAQASPARGGRKPSLPEATPSRKAVAPTVVTSCPRGSPGHDTHRSASDPSKTGTQS
                     EQRVDGSRPEPPASDKTSGGGGRRPLPSPAPPPPRQPEAQGIPKEPGGEGTDSVLRTP
                     PVGMSGQAALPPLLSDSAYLSPSARGRHLERGLLTTTVTLQQPVELNGEDELVFTVVE
                     ELPLGGLAGATRPSSLASMSSDCSLQALASGSRPVSIISSINDEFDAYTSQMSEGPGD
                     PGEFPEGTAWAGGSPASSIGSWLSDVGVCLSESRGPTPQPPFSPNSAAGPGPPEFPTP
                     GSSLEESKVRSSECGRPDNPGSARSLHPGEAVATTQTQPGREPWARSPHEVASAQTIH
                     SSLPRKPRTTSTASRARPSRGPYSPGGLFEDPWLLRAEDCDTRQIASTGRAPSPTPGS
                     PRLPETQMMLACAQRVVDGCEVASRMSRRPEAVARIPPLRRGATTLGVTTPAASCGDA
                     PAEAVVHSGSLKTTSGSKKSVSPKGAFFPRPSGAGPPAPPVRKSSLEQSTALTPTQAL
                     GLTRAGAPSAFRGEEEARPSGRSDSSVPKATSSLKARAGKMDVPYRPSGHMSLERCEG
                     LAHGSSKVRDVVGRPPRAVPRLGVPSASPPLGPAPACRNSPAKGVGATKPPAGGAKGR
                     NLGPSTSRALGAPVKPLGPVAGKTAGGAVPGPRAAPRAVPGIGAKAGRGTIMGTKQAF
                     RAAHSRVHELAASGSPSRGGLSWGSTDSDSGNDSGVNLAEERQPSSPALPSPYSKVTA
                     PRRPQRYSSGHGSDNSSVLSGELPPAMGRTALFYHSGGSSGYESMIRDSEATGSASSA
                     PDSMSESGTASLGARSRSLKSPKKRATGLQRRRLIPAPLPDAAALGRKPSLPGQWVDL
                     PPPLAGSLKEPFEIKVYEIDDVERLQRHRLPLRENEAKPSQDAEKGPVCISSKLRLAE
                     RRQQRLQEVQAKRDHLCEELAETQGRLMVEPGRWLEQFEVDPELEPESAEYLVALEQA
                     TAALEQCVNLCKAHVMMVTCFDIGVAATTAVPGPQEVDV"
     exon            200..442
                     /gene="Kif26a"
                     /gene_synonym="mKIAA1236"
                     /inference="alignment:Splign:2.1.0"
     exon            443..868
                     /gene="Kif26a"
                     /gene_synonym="mKIAA1236"
                     /inference="alignment:Splign:2.1.0"
     exon            869..1059
                     /gene="Kif26a"
                     /gene_synonym="mKIAA1236"
                     /inference="alignment:Splign:2.1.0"
     exon            1060..1249
                     /gene="Kif26a"
                     /gene_synonym="mKIAA1236"
                     /inference="alignment:Splign:2.1.0"
     exon            1250..1462
                     /gene="Kif26a"
                     /gene_synonym="mKIAA1236"
                     /inference="alignment:Splign:2.1.0"
     exon            1463..1556
                     /gene="Kif26a"
                     /gene_synonym="mKIAA1236"
                     /inference="alignment:Splign:2.1.0"
     exon            1557..1819
                     /gene="Kif26a"
                     /gene_synonym="mKIAA1236"
                     /inference="alignment:Splign:2.1.0"
     exon            1820..2003
                     /gene="Kif26a"
                     /gene_synonym="mKIAA1236"
                     /inference="alignment:Splign:2.1.0"
     exon            2004..2166
                     /gene="Kif26a"
                     /gene_synonym="mKIAA1236"
                     /inference="alignment:Splign:2.1.0"
     exon            2167..2329
                     /gene="Kif26a"
                     /gene_synonym="mKIAA1236"
                     /inference="alignment:Splign:2.1.0"
     exon            2330..5243
                     /gene="Kif26a"
                     /gene_synonym="mKIAA1236"
                     /inference="alignment:Splign:2.1.0"
     exon            5244..5449
                     /gene="Kif26a"
                     /gene_synonym="mKIAA1236"
                     /inference="alignment:Splign:2.1.0"
     exon            5450..5470
                     /gene="Kif26a"
                     /gene_synonym="mKIAA1236"
                     /inference="alignment:Splign:2.1.0"
     exon            5471..5621
                     /gene="Kif26a"
                     /gene_synonym="mKIAA1236"
                     /inference="alignment:Splign:2.1.0"
     exon            5622..6918
                     /gene="Kif26a"
                     /gene_synonym="mKIAA1236"
                     /inference="alignment:Splign:2.1.0"
     regulatory      6895..6900
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Kif26a"
                     /gene_synonym="mKIAA1236"
                     /note="hexamer: AATAAA"
     polyA_site      6916
                     /gene="Kif26a"
                     /gene_synonym="mKIAA1236"
                     /note="major polyA site"
ORIGIN      
        1 gtcccggagc aagccggtcg cgtccacagc gtgctctccg ccactcgcct gctctgccaa
       61 cttcagagca gcaggcctgg ccatgggggt gcccctgggc cggatcacgt agccactgta
      121 ccccgagagc caacgtatcc cttcctgcga ccgtgccatg gtcggccgcg gcgcctcctt
      181 gtgtgcggtg cagcccgcgg tggctgagtg cggcccggct cgagagaccc cgccacttga
      241 ggtatccccg cgcaagaggc tgcccgccgg gctcgatcaa gacccatgca gcagccgccc
      301 tgctccggag ggcgccgggg ccagcgctga gcagagccac tcggccggtg ggggcgggtg
      361 gtgccgccac tgccacacga agctcgtgga gctaaaacga caggcgtgga agttggtcag
      421 cgggcccggg actcctctcc gggatccttg cctctctacc ttgctgcttg acaagctccc
      481 ggcctctggg gttcagccgg catgccgccc tgacaccgag agccgctgtg acgtatgtac
      541 cacgcatctg caccagctca ctcgggaagc cctgcgcctg ttacagacac ctgccagtca
      601 cgaggacccc aatgcttccc gaggaggcct tgcggctccc agctccaggg acccacctgg
      661 acccgtgggc ctcatgggga ggcagccccc tgtgggacct gacaggagga aggcaacggc
      721 ttggccacct ggccccagcg tccaggtgtc ggtggcacca gcaggccttg ggggagcatt
      781 gagtacagtc accatccagg cccagcagtg cttggagggt gtgtggagcc tctcaagggt
      841 caacagcttc ttgccaccca cttgcctggc tgaggcagct gtagctgcgg tggctgtggc
      901 cgacactgtc cgagactgtg ctccagcagc aggccctgaa cgtatgtcga aggcgtgggg
      961 ccgaggggca gcatgcacta cagccctggt taccccagcc ccaggcacct cagcaggggg
     1021 ttccacaggc ccgtctgcag cggcctcttt ctttataagg gctgcccaga agctcagcct
     1081 ggcctccaag cgcaagaagc atcacccgcc gcctgcgccc tccacccgag gcacatccac
     1141 ttaccccacc gacttcagtg gctctctgca gctgtggccg cccccggtgc ccccctgcct
     1201 gctcagggct gcctccaagg ccaaggaaaa ccccagcagc ttcggaaagg tgaaggttat
     1261 gctgcgcata tggccggcac aaggagtcca gcgctcagcc gagtccacat ccttcctgaa
     1321 ggtggattct cgcaagaagc aggtgactct ctatgacccc gctgccgggc ctccaggctg
     1381 tgcaggactc cggcacgccc ccaccgcacc agtccccaag atgtttgctt ttgatgccat
     1441 cttcccccag gactcggagc aggctgaggt ctgctcaggg acagtggctg acgtgctcca
     1501 gtctgtggtc agtggagctg atggctgcat tttttccttt ggccacatga gcctcggcaa
     1561 atcatacacc atgattggga aggacagctc accccagagc ctgggcatcg tgccctgtgc
     1621 tatctcctgg ctcttcaggc ttattgacga acgcaaggag aggctgggca cgcgcttctc
     1681 catccgcgtg tctgccgtgg aagtgtgcgg ccacgaccag agtctgcggg acctgcttgc
     1741 cgaggtggct tcaggcagcc ttcaggacac ccaatctccg ggcgtgtacc tccgggagga
     1801 ccctgtgtgt gggacacagc tccagaacca gaacgagctg cgtgcaccca cagcagagaa
     1861 ggcggccttc tacctggacg cggccctggc agcccgcagc accagccgtg ccggctgcgg
     1921 ggaggaagcc cggcgaagct cccatatgct cttcaccctg cacgtgtacc agtaccgtgt
     1981 ggagaagtgt ggccaaggag gaatgtctgg aggtcgtagc cgcctgcacc tgatcgacct
     2041 gggcagctgc gacgcagccg tcggcagagg aggagaagcc tcagggggac ccctctgtct
     2101 gtctctgtca gctctgggca gtgtcattct ggccctggtc aacggggcca agcatgtgcc
     2161 ctacagggac cacagactca ccatgttact gcgggagtcc ctggctacca ccaattgccg
     2221 caccactatg atcgcgcaca tctcagactc tccagctcac cacgcagaga cactcagcac
     2281 ggtgcagctg gctgcccgca tccaccgcct gcgcaggaag aagggcaagc atgcatccag
     2341 ttcctcagga ggagagagct cctgtgagga gggccgagcc cgccgtcccc cacaccttcg
     2401 gcccttccac ccacgggccg tggtgttgga ccccgaccgc tcggctcctg gcctgtccgg
     2461 agaccccgat tactcatcca gcagtgagca gtcctgcgac acggtcatct atgtgggtcc
     2521 cggtgggatg gcactgtcag accgtgagct cacggacaac gagggcccac ctgacttcgt
     2581 gcccatcatc cccgctctga gccgacgcag gccctccgag gggccccggg acgctgacca
     2641 cttccgctgc agtacgttcg ccgagctgca ggagcgtctg gagtgcatag atggcagcga
     2701 ggcattccct ggcccccagg gtggctctga cggagcccaa gccagccctg cccggggagg
     2761 caggaaaccc tcgttacctg aggccacacc ctccaggaag gctgtggccc ccacagtggt
     2821 caccagttgc cctcgaggca gccctgggca cgatactcac cggagcgcct cagacccctc
     2881 taagactggt acacagagtg agcagagagt agatggttcc cggcctgagc cacctgcttc
     2941 agacaagacc tcaggaggcg ggggcaggag gccactgccc agtccagccc ctccaccgcc
     3001 tcgccagccg gaagctcaag gcatccccaa agaacctggg ggagagggta ctgacagcgt
     3061 gctgcggaca cccccagtgg gcatgagtgg acaggcggcc ttgcccccgt tgctctcaga
     3121 ctcggcttat ctctccccgt cggctcgtgg acgccatctg gagagaggcc tgctgaccac
     3181 cacggtgacc ttgcagcaac cggtggaact caatggcgag gatgagttgg tgttcacggt
     3241 ggtagaggag ctacctctgg gcggacttgc aggggccaca cggccctcca gtctggccag
     3301 catgagcagc gactgctccc tgcaggcttt ggcttcaggg tccaggccag tcagtatcat
     3361 cagtagcatc aatgacgagt ttgatgctta tacctcacag atgtctgagg gtcccggaga
     3421 ccccggggag ttcccagagg gaacagcgtg ggctggcggc agtccagcct cctccattgg
     3481 ctcttggctg agcgacgttg gtgtctgctt gtctgaaagc cgtggtccca caccacagcc
     3541 tcccttcagc cccaactctg cagcagggcc aggtccacca gagtttccta ccccaggcag
     3601 ctccctagag gaaagcaagg tcaggtcctc agagtgtgga agaccagaca atcccggctc
     3661 agcccggagt ctccaccctg gagaagcagt tgcaacaact cagacccaac ctggcagaga
     3721 gccttgggcc aggtccccgc atgaggtagc ctcagcccag actatccact ccagcctgcc
     3781 tcggaaaccc aggactacct ccacagccag ccgagctcgt cctagccggg gaccatacag
     3841 ccctggtggc ctgtttgagg acccttggct gctccgggca gaggactgtg acacgcgcca
     3901 gatagcctct acgggcagag ccccaagccc aaccccaggc tcccctcgat tgcctgagac
     3961 tcagatgatg ctggcttgtg cccagagagt ggtagatggg tgtgaggtgg catccagaat
     4021 gtcgcggaga ccagaggctg tggctcggat cccacctttg cggagggggg ccaccacact
     4081 aggagtgacc acacctgctg catcctgtgg ggacgctcca gcagaggcag tggtccattc
     4141 aggaagcctg aagaccacct cgggcagtaa gaagagtgtt tctcccaagg gggccttctt
     4201 tccaaggcct agtggggcag ggcctccagc cccacctgtg cgcaagtcga gcctggagca
     4261 gagcacggcc ctcaccccca cccaggccct gggactgacc agggcagggg ctccttctgc
     4321 cttccgaggg gaggaggaag ccaggcctag tggtcggtct gattcctctg ttcccaaggc
     4381 cacatccagc ctgaaagccc gagctggcaa gatggacgtg ccataccgtc cctctggcca
     4441 catgtccctg gaacggtgtg agggcctggc acatggcagc agtaaggtca gagatgtcgt
     4501 aggacggcca ccaagggctg tgcccaggtt gggtgtacca tccgccagcc ctccacttgg
     4561 accagctcct gcctgtagga acagcccagc caagggtgtt ggagcaacca agcctcctgc
     4621 tggtggagct aagggtcgta atctggggcc aagtacatct cgggctctgg gtgctccggt
     4681 gaagccacta gggcctgtgg caggcaagac agctggtggc gctgtgccag gaccccgagc
     4741 tgctccacgg gctgtgccgg gtattggggc caaggccggt cggggcacca tcatgggcac
     4801 taagcaggca tttcgggctg cccatagccg tgtccacgaa ttggcagcca gtggatctcc
     4861 tagtagaggt ggcctctcct ggggctcgac ggactcggac agcggcaacg acagcggtgt
     4921 gaacctggct gaagagcggc agccctcgag ccctgccctg ccctcccctt acagcaaagt
     4981 gaccgctccg aggagacccc agcgctacag cagtggccat ggcagtgaca acagcagcgt
     5041 gctgagcggc gagctgcccc ccgccatggg ccgcactgct cttttctacc acagtggcgg
     5101 cagcagtggc tacgagagca tgattcggga cagcgaggcc actggcagtg cctcctcagc
     5161 tccagactcc atgagtgaga gtggaacggc ctccctgggt gcccgctccc gcagcctcaa
     5221 gtccccgaag aagagagcca caggtctaca gcggaggagg ctgatcccgg ccccacttcc
     5281 tgacgctgct gctttaggcc gcaagcccag cctccccggg caatgggtgg acttgccccc
     5341 gcccctggcc ggctctctga aggagccttt tgagatcaag gtgtacgaaa tagatgacgt
     5401 ggagcgtctg cagcggcacc ggctgcctct gagggagaat gaagccaagc cctcccagga
     5461 cgcagagaag ggcccagtgt gcatcagctc caagctgcgt ctcgcagagc gcaggcagca
     5521 gcgactgcag gaagtgcagg ccaaacgtga ccacctctgc gaggagctgg ctgagaccca
     5581 gggccggctg atggtggaac ctgggcgctg gctagagcag tttgaggtgg acccagagct
     5641 ggagccagag tcagctgaat atctggtggc cctggagcaa gccacagctg ccctggagca
     5701 gtgcgttaac ctgtgcaagg cccatgtcat gatggtcacc tgctttgaca ttggagttgc
     5761 tgccaccact gctgtacctg ggccacaaga ggtggatgtt tgaggctgaa cacagggcgt
     5821 aggcaggaca tgcaaggcag agggtgtgag cgtaatgtgg gatggagtga ggatgtggag
     5881 ggggttggcg ggttgaagac gcagggtctg tgcaggacca ggggatctca gagaggagac
     5941 agagggtggg aaggggaggg ccagccagtg gacagagagc gcacggagat ggaaagactg
     6001 tcgccaccca gacagccacg caagtgcctt taactttgag taggcctttt ctccttttct
     6061 aatttggtgc tacggactca agacagaact cagacaccag cagacagagt ctcaacctag
     6121 gtggctgcag ccactctggc cagacgaaag ccagtttgtt tctgattttg ccttccttac
     6181 aaccaagcag ttttgtgtag cagggcaggc ctgttctggc cagctttctt ttaggattgg
     6241 tttagttttt cttttcagaa gttttctctc aacagtccgc ttgagtggcc accaccacac
     6301 taacagtggt gtcctcggag tgtggacagc tagctgtcag tcccctcctc tccttgaggg
     6361 ccccactccg ttctgaggac accagaggcc acaaactagg gctgggccat gagcacacaa
     6421 tgctttcttc cacggcagga attcttacca aaaccacaag caaaaaaaat aaaacaaaca
     6481 aaaaaaaaaa aaaacaaaac aatgacgcga atcaccgcca acaaagacgg gggtgtgggt
     6541 ttttgtaaaa gttctgttag cttcatattt ttgtatcatt ttgcctataa acatagagct
     6601 tgcagtggga atttgaagac aaatgatcta tgtttttatg gttttgtaca ggtattccca
     6661 ggttgggggc tcttggcagc tgtgaggggg caggcttttc ctgggggaca ctgggggcat
     6721 tgtggggggg tctatgggag gctgttcttt tcagatgcag acgagggttg agcctgccag
     6781 cctgtgatgt ggcctgcacg caggttcgtg ctttctgact gttatgtatt ttctaagcgt
     6841 ccagaccttt gtacaaatgt gtagataaca atctcacggc tgtttttatt tgtgaataaa
     6901 agatgtgttg attgttta
//
