LOCUS       NM_001405055            3406 bp    mRNA    linear   ROD 18-FEB-2025
DEFINITION  Mus musculus kinesin family member 23 (Kif23), transcript variant
            1, mRNA.
ACCESSION   NM_001405055 XM_006511452
VERSION     NM_001405055.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3406)
  AUTHORS   Naher,S., Iemura,K., Miyashita,S., Hoshino,M., Tanaka,K., Niwa,S.,
            Tsai,J.W., Kikkawa,T. and Osumi,N.
  TITLE     Kinesin-like motor protein KIF23 maintains neural stem and
            progenitor cell pools in the developing cortex
  JOURNAL   EMBO J 44 (2), 331-355 (2025)
   PUBMED   39632980
REFERENCE   2  (bases 1 to 3406)
  AUTHORS   Rao,X., Lei,Z., Zhu,H., Luo,K. and Hu,C.
  TITLE     Knockdown of KIF23 alleviates the progression of asthma by
            inhibiting pyroptosis
  JOURNAL   BMJ Open Respir Res 11 (1), e002089 (2024)
   PUBMED   38569671
  REMARK    GeneRIF: Knockdown of KIF23 alleviates the progression of asthma by
            inhibiting pyroptosis.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3406)
  AUTHORS   Kolesova,H., Hrabalova,P., Bohuslavova,R., Abaffy,P.,
            Fabriciova,V., Sedmera,D. and Pavlinkova,G.
  TITLE     Reprogramming of the developing heart by Hif1a-deficient
            sympathetic system and maternal diabetes exposure
  JOURNAL   Front Endocrinol (Lausanne) 15, 1344074 (2024)
   PUBMED   38505753
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 3406)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 3406)
  AUTHORS   Vikberg,A.L., Malla,S. and Golovleva,I.
  TITLE     Differential tissue specific expression of Kif23 alternative
            transcripts in mice with the human mutation causing congenital
            dyserythropoietic anemia type III
  JOURNAL   Blood Cells Mol Dis 85, 102483 (2020)
   PUBMED   32818800
  REMARK    GeneRIF: Differential tissue specific expression of Kif23
            alternative transcripts in mice with the human mutation causing
            congenital dyserythropoietic anemia type III.
REFERENCE   6  (bases 1 to 3406)
  AUTHORS   Janisch,K.M., Vock,V.M., Fleming,M.S., Shrestha,A.,
            Grimsley-Myers,C.M., Rasoul,B.A., Neale,S.A., Cupp,T.D.,
            Kinchen,J.M., Liem,K.F. Jr. and Dwyer,N.D.
  TITLE     The vertebrate-specific Kinesin-6, Kif20b, is required for normal
            cytokinesis of polarized cortical stem cells and cerebral cortex
            size
  JOURNAL   Development 140 (23), 4672-4682 (2013)
   PUBMED   24173802
REFERENCE   7  (bases 1 to 3406)
  AUTHORS   Chang,Y.C., Chen,Y.J., Wu,C.H., Wu,Y.C., Yen,T.C. and Ouyang,P.
  TITLE     Characterization of centrosomal proteins Cep55 and pericentrin in
            intercellular bridges of mouse testes
  JOURNAL   J Cell Biochem 109 (6), 1274-1285 (2010)
   PUBMED   20186884
REFERENCE   8  (bases 1 to 3406)
  AUTHORS   Greenbaum,M.P., Iwamori,N., Agno,J.E. and Matzuk,M.M.
  TITLE     Mouse TEX14 is required for embryonic germ cell intercellular
            bridges but not female fertility
  JOURNAL   Biol Reprod 80 (3), 449-457 (2009)
   PUBMED   19020301
REFERENCE   9  (bases 1 to 3406)
  AUTHORS   Kuriyama,R., Gustus,C., Terada,Y., Uetake,Y. and Matuliene,J.
  TITLE     CHO1, a mammalian kinesin-like protein, interacts with F-actin and
            is involved in the terminal phase of cytokinesis
  JOURNAL   J Cell Biol 156 (5), 783-790 (2002)
   PUBMED   11877456
REFERENCE   10 (bases 1 to 3406)
  AUTHORS   Miki,H., Setou,M., Kaneshiro,K. and Hirokawa,N.
  TITLE     All kinesin superfamily protein, KIF, genes in mouse and human
  JOURNAL   Proc Natl Acad Sci U S A 98 (13), 7004-7011 (2001)
   PUBMED   11416179
  REMARK    Review article
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC151969.3.
            
            On Apr 19, 2022 this sequence version replaced XM_006511452.5.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR13948564.1627934.1,
                                           SRR17253011.6106312.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164143 [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-126               AC151969.3         105516-105641       c
            127-196             AC151969.3         104254-104323       c
            197-325             AC151969.3         103107-103235       c
            326-431             AC151969.3         96334-96439         c
            432-568             AC151969.3         95986-96122         c
            569-678             AC151969.3         95567-95676         c
            679-849             AC151969.3         94284-94454         c
            850-891             AC151969.3         92133-92174         c
            892-1004            AC151969.3         90979-91091         c
            1005-1126           AC151969.3         90705-90826         c
            1127-1229           AC151969.3         88568-88670         c
            1230-1309           AC151969.3         86458-86537         c
            1310-1429           AC151969.3         86252-86371         c
            1430-1556           AC151969.3         85941-86067         c
            1557-1715           AC151969.3         85264-85422         c
            1716-1873           AC151969.3         84434-84591         c
            1874-2047           AC151969.3         83874-84047         c
            2048-2227           AC151969.3         83536-83715         c
            2228-2539           AC151969.3         82809-83120         c
            2540-2767           AC151969.3         79923-80150         c
            2768-2850           AC151969.3         78779-78861         c
            2851-2932           AC151969.3         78516-78597         c
            2933-3003           AC151969.3         77804-77874         c
            3004-3406           AC151969.3         76181-76583         c
FEATURES             Location/Qualifiers
     source          1..3406
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 33.5 cM"
     gene            1..3406
                     /gene="Kif23"
                     /gene_synonym="3110001D19Rik; CHO1; Knsl5; MKLP-1; MKLP1"
                     /note="kinesin family member 23"
                     /db_xref="GeneID:71819"
                     /db_xref="MGI:MGI:1919069"
     exon            1..126
                     /gene="Kif23"
                     /gene_synonym="3110001D19Rik; CHO1; Knsl5; MKLP-1; MKLP1"
                     /inference="alignment:Splign:2.1.0"
     CDS             116..3019
                     /gene="Kif23"
                     /gene_synonym="3110001D19Rik; CHO1; Knsl5; MKLP-1; MKLP1"
                     /note="isoform 1 is encoded by transcript variant 1;
                     kinesin-like 5 (mitotic kinesin-like protein 1);
                     kinesin-like protein KIF23"
                     /codon_start=1
                     /product="kinesin-like protein KIF23 isoform 1"
                     /protein_id="NP_001391984.1"
                     /db_xref="GeneID:71819"
                     /db_xref="MGI:MGI:1919069"
                     /translation="MKSAKAKTVRKPVIKKGSQTNLKDPVGVYCRVRPLSFPDQECCV
                     EVINSTTLQLHTPEGYRLNRNGDYKETQYSFKRVFGTHTTQKELFDVVANPLVDDLIH
                     GKNGLLFTYGVTGSGKTYTMTGSPGSGGLLPRCLNMIFNSIGSFQAKRYVFKSNDRNS
                     MEIQCEVDALLERQKREALPIPKTPSSKRQADPEFADMINVQEFCKAEEVDEDSVYGV
                     FVSYIEIYNNYIYDLLEEVQFDPIKPKWNGCSTPMRNAESVLPQSKTLREDKNHNMYV
                     AGCTEVEVKSTEEAFEVFWRGQKKRRIANTHLNRESSRSHSVFSIKLVQAPLDADGDN
                     VLQEKEQITISQLSLVDLAGSERTNRTKAEGNRLREAGNINQSLMTLRTCMEVLRENQ
                     TYGTNKMVPYRDSKLTHLFKNYFDGEGKVRMIVCVNPKAEDYEESLQVMRFAEVTQEV
                     EVARPVDKVICGLTPGRRYRNLPRGGPVGDEPLVPEVILQSFPPLPPCKLLDINDEET
                     LPKLADTLEKRHHLRQLMTEDLNKKCLAFKALLKEFDNSLSNKENYVQEKLNEREKVI
                     SGQKLEIERLEKKNKTLEYKIEILEKTTTIYEEDKRNLQQELESQNQKLQRQFSDKRR
                     LEARLQGMVTETSMKWQKECERRVAATQLEMQNKLWVKDEKLKQLKAIVTEPKPEKPE
                     RPSRERDREKIIPRSVSPSPLPLSSNNIAQISNGQQLMSQPQLHRRSNSCSSISVASC
                     ISEWEQKLSPFSTPVNVTSLARHRQQEPGQSKTCIVSDRRRGMCWTEGREMVPTFSSE
                     IGVEEDHCRRNTPIPVRHRRSRSAGSRWVDHKPASNVQTETVMQPHVPHAITVSVANE
                     KALAKCEKYMLTHQELASDGEIQTKVIKGDVYKTRGGGQSVQFTDIETLKQELPTGSR
                     KRRSSTLAPAQPDGTESEWTDVETRCSVAVEMRAGSQLGPGYQHHAQPKRKKP"
     exon            127..196
                     /gene="Kif23"
                     /gene_synonym="3110001D19Rik; CHO1; Knsl5; MKLP-1; MKLP1"
                     /inference="alignment:Splign:2.1.0"
     exon            197..325
                     /gene="Kif23"
                     /gene_synonym="3110001D19Rik; CHO1; Knsl5; MKLP-1; MKLP1"
                     /inference="alignment:Splign:2.1.0"
     exon            326..431
                     /gene="Kif23"
                     /gene_synonym="3110001D19Rik; CHO1; Knsl5; MKLP-1; MKLP1"
                     /inference="alignment:Splign:2.1.0"
     exon            432..568
                     /gene="Kif23"
                     /gene_synonym="3110001D19Rik; CHO1; Knsl5; MKLP-1; MKLP1"
                     /inference="alignment:Splign:2.1.0"
     exon            569..678
                     /gene="Kif23"
                     /gene_synonym="3110001D19Rik; CHO1; Knsl5; MKLP-1; MKLP1"
                     /inference="alignment:Splign:2.1.0"
     exon            679..849
                     /gene="Kif23"
                     /gene_synonym="3110001D19Rik; CHO1; Knsl5; MKLP-1; MKLP1"
                     /inference="alignment:Splign:2.1.0"
     exon            850..891
                     /gene="Kif23"
                     /gene_synonym="3110001D19Rik; CHO1; Knsl5; MKLP-1; MKLP1"
                     /inference="alignment:Splign:2.1.0"
     exon            892..1004
                     /gene="Kif23"
                     /gene_synonym="3110001D19Rik; CHO1; Knsl5; MKLP-1; MKLP1"
                     /inference="alignment:Splign:2.1.0"
     exon            1005..1126
                     /gene="Kif23"
                     /gene_synonym="3110001D19Rik; CHO1; Knsl5; MKLP-1; MKLP1"
                     /inference="alignment:Splign:2.1.0"
     exon            1127..1229
                     /gene="Kif23"
                     /gene_synonym="3110001D19Rik; CHO1; Knsl5; MKLP-1; MKLP1"
                     /inference="alignment:Splign:2.1.0"
     exon            1230..1309
                     /gene="Kif23"
                     /gene_synonym="3110001D19Rik; CHO1; Knsl5; MKLP-1; MKLP1"
                     /inference="alignment:Splign:2.1.0"
     exon            1310..1429
                     /gene="Kif23"
                     /gene_synonym="3110001D19Rik; CHO1; Knsl5; MKLP-1; MKLP1"
                     /inference="alignment:Splign:2.1.0"
     exon            1430..1556
                     /gene="Kif23"
                     /gene_synonym="3110001D19Rik; CHO1; Knsl5; MKLP-1; MKLP1"
                     /inference="alignment:Splign:2.1.0"
     exon            1557..1715
                     /gene="Kif23"
                     /gene_synonym="3110001D19Rik; CHO1; Knsl5; MKLP-1; MKLP1"
                     /inference="alignment:Splign:2.1.0"
     exon            1716..1873
                     /gene="Kif23"
                     /gene_synonym="3110001D19Rik; CHO1; Knsl5; MKLP-1; MKLP1"
                     /inference="alignment:Splign:2.1.0"
     exon            1874..2047
                     /gene="Kif23"
                     /gene_synonym="3110001D19Rik; CHO1; Knsl5; MKLP-1; MKLP1"
                     /inference="alignment:Splign:2.1.0"
     exon            2048..2227
                     /gene="Kif23"
                     /gene_synonym="3110001D19Rik; CHO1; Knsl5; MKLP-1; MKLP1"
                     /inference="alignment:Splign:2.1.0"
     exon            2228..2539
                     /gene="Kif23"
                     /gene_synonym="3110001D19Rik; CHO1; Knsl5; MKLP-1; MKLP1"
                     /inference="alignment:Splign:2.1.0"
     exon            2540..2767
                     /gene="Kif23"
                     /gene_synonym="3110001D19Rik; CHO1; Knsl5; MKLP-1; MKLP1"
                     /inference="alignment:Splign:2.1.0"
     exon            2768..2850
                     /gene="Kif23"
                     /gene_synonym="3110001D19Rik; CHO1; Knsl5; MKLP-1; MKLP1"
                     /inference="alignment:Splign:2.1.0"
     exon            2851..2932
                     /gene="Kif23"
                     /gene_synonym="3110001D19Rik; CHO1; Knsl5; MKLP-1; MKLP1"
                     /inference="alignment:Splign:2.1.0"
     exon            2933..3003
                     /gene="Kif23"
                     /gene_synonym="3110001D19Rik; CHO1; Knsl5; MKLP-1; MKLP1"
                     /inference="alignment:Splign:2.1.0"
     exon            3004..3406
                     /gene="Kif23"
                     /gene_synonym="3110001D19Rik; CHO1; Knsl5; MKLP-1; MKLP1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3381..3386
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Kif23"
                     /gene_synonym="3110001D19Rik; CHO1; Knsl5; MKLP-1; MKLP1"
                     /note="hexamer: AATAAA"
     polyA_site      3406
                     /gene="Kif23"
                     /gene_synonym="3110001D19Rik; CHO1; Knsl5; MKLP-1; MKLP1"
                     /note="major polyA site"
ORIGIN      
        1 agattgagtc ctggtccccg cggccgtggt ttgctcggct tagttcccgc cagccttgct
       61 cctgtcggag cccgacgtcc cgcgcgcgcg tcaggatagc acggagcctg cggtcatgaa
      121 gtcagcgaag gctaagacgg tcagaaaacc tgtaataaaa aaaggatctc agacaaacct
      181 taaagatcca gtgggggtgt actgtagggt tcgccccctg agctttcctg accaagaatg
      241 ctgtgtggaa gtgatcaata gtacaaccct gcagctccac actcctgagg gctatcgact
      301 caacagaaat ggggactata aggagactca gtactcattc aagcgggtat ttggcactca
      361 caccacccag aaggaacttt ttgatgttgt agctaatccc ttggtagatg acctcattca
      421 tggcaagaat ggtcttttat ttacatatgg cgtgacggga agtggaaaaa cctacacaat
      481 gacagggtct ccagggtctg gaggcctgct tcctcgttgt ttgaatatga tctttaacag
      541 catagggtca tttcaagcaa aacgttatgt gtttaagtct aatgatagga acagtatgga
      601 aatacagtgt gaagtcgatg ccttgttaga acggcagaaa agagaagcct tgcccattcc
      661 aaagaccccc tctagcaagc gacaagcaga tccagagttt gcagatatga taaatgtaca
      721 agaattctgc aaagcagaag aagttgatga agacagtgtc tatggagtat ttgtctctta
      781 cattgaaatc tataataatt acatatatga tctattggaa gaagtgcagt ttgatcccat
      841 aaagcccaag tggaacggct gcagtacacc tatgaggaac gcagagtctg tactcccaca
      901 atctaaaacg ctccgagaag ataagaacca caatatgtat gtggcaggat gtacagaagt
      961 agaagtgaaa tctacggagg aggcttttga ggttttctgg agagggcaga aaaagagacg
     1021 cattgctaac acccatttga atagagagtc cagtcgttca catagcgtgt tcagcattaa
     1081 acttgtccag gctcccctgg atgctgatgg agacaatgtc ttacaggaaa aagagcaaat
     1141 tactataagc cagctgtctc tggtagatct tgctgggagc gaaagaacca accgtactaa
     1201 agcagaaggg aacagactac gtgaggccgg aaacattaat cagtcattga tgacactaag
     1261 aacatgcatg gaggtcctga gagagaacca gacgtatggc actaacaaga tggttccata
     1321 tcgagattca aagctaaccc atctattcaa gaactacttc gatggggagg ggaaagttcg
     1381 gatgatcgtg tgtgtgaatc caaaggctga agactatgaa gaaagcttgc aagtcatgag
     1441 atttgctgaa gtaacccaag aagtggaagt ggcaagacca gtggacaagg tgatatgtgg
     1501 cctgacaccc gggaggcggt acaggaacct gcctcgggga ggccccgttg gagatgaacc
     1561 tttggtgcct gaagtgattc tacagagctt cccaccgctg cccccatgca agcttttgga
     1621 tatcaatgat gaggagaccc ttccaaagct ggctgacact ttggagaaac gacatcacct
     1681 gcgacaacta atgaccgagg accttaacaa aaaatgtcta gctttcaagg ccttattaaa
     1741 agaatttgac aattctctat caaataaaga aaactacgtt caggaaaaac taaatgaaag
     1801 agaaaaagtg atctcgggac agaaattgga aatagagcga ctggagaaga aaaacaaaac
     1861 tttggagtac aagattgaga ttctggagaa aacaactacg atctatgagg aagataagcg
     1921 caatctgcag caggagcttg agagccagaa tcagaagctt cagcggcagt tttctgacaa
     1981 gcgcagatta gaagccaggt tgcaaggcat ggtaacagaa acgtcgatga agtggcagaa
     2041 ggaatgtgag cgtcgggtgg cagccaccca gctagagatg cagaataaac tctgggtcaa
     2101 agatgaaaag ctcaaacagc tgaaggccat tgtgactgaa cccaaacctg agaagccaga
     2161 gagaccctcc cgggagcggg accgggagaa aatcattccg agatctgtct ctccttcgcc
     2221 tctacctctt tctagtaaca atattgctca gatttccaac ggccagcaac tcatgagcca
     2281 gccgcagcta cacagacgct ctaactcttg cagcagcatt tctgtagctt cctgtatctc
     2341 ggaatgggag cagaaactat ctccattcag cacacctgtc aatgtcacct cccttgcaag
     2401 gcataggcag caggagccag gacaaagtaa aacgtgtatc gtgtcagaca gaaggcgagg
     2461 catgtgctgg actgaaggca gggagatggt ccccacattc agcagtgaga taggcgtaga
     2521 agaggaccat tgccgcagga acaccccaat tcctgtacga cacagaaggt cccgctctgc
     2581 agggagcaga tgggtagatc ataagcctgc ctctaatgtg caaactgaga cagtgatgca
     2641 gccgcatgtc cctcacgcca tcacagtgtc tgttgcaaat gaaaaggcgc tagctaagtg
     2701 tgagaagtac atgctgaccc accaggaact agcctccgat ggggagattc agactaaagt
     2761 cattaagggt gatgtttata agacgagagg tggcggacaa tcggttcagt ttactgatat
     2821 tgagacttta aaacaagaat tgccaactgg tagtcggaaa cgaagatcgt ccaccctagc
     2881 acctgcccaa ccagatggta cagagtctga atggaccgat gtagaaacaa ggtgctctgt
     2941 tgccgttgaa atgagagcag gatctcagct gggaccggga tatcagcacc acgcacaacc
     3001 caagcgcaag aaaccttgaa ctgacagccc cggcaccaga agaccgtttt tactcgtgtt
     3061 ggtgatttat ccaaagctgt tccagacgca gtgtctgagt catcttgcag aagaatgtat
     3121 ccagatcacg ttgccctttt ttattgtgac tttttcaact gctctgaata ttttctaagg
     3181 ttttataaaa aaaaaaaaaa aacaaacaaa tgctgctatt gattagctgc aaaaaaaaat
     3241 gcactttaga catatttaac aattaagact ttcataataa agatggcgac tggccagtgg
     3301 tgaaaccatt ttaggaaggt atttagagtt ttgtatgtat atattcactt tctgaccttt
     3361 atatatgcca aaacaactga aataaaaagg cactaagaga tgcaaa
//
