LOCUS       NM_001039472            9117 bp    mRNA    linear   ROD 09-FEB-2025
DEFINITION  Mus musculus kinesin family member 21B (Kif21b), transcript variant
            1, mRNA.
ACCESSION   NM_001039472
VERSION     NM_001039472.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 9117)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 9117)
  AUTHORS   Rivera Alvarez,J., Asselin,L., Tilly,P., Benoit,R., Batisse,C.,
            Richert,L., Batisse,J., Morlet,B., Levet,F., Schwaller,N., Mely,Y.,
            Ruff,M., Reymann,A.C. and Godin,J.D.
  TITLE     The kinesin Kif21b regulates radial migration of cortical
            projection neurons through a non-canonical function on actin
            cytoskeleton
  JOURNAL   Cell Rep 42 (7), 112744 (2023)
   PUBMED   37418324
  REMARK    GeneRIF: The kinesin Kif21b regulates radial migration of cortical
            projection neurons through a non-canonical function on actin
            cytoskeleton.
REFERENCE   3  (bases 1 to 9117)
  AUTHORS   Gromova,K.V., Thies,E., Janiesch,P.C., Lutzenkirchen,F.P., Zhu,Y.,
            Stajano,D., Durst,C.D., Schweizer,M., Konietzny,A., Mikhaylova,M.,
            Gee,C.E. and Kneussel,M.
  TITLE     The kinesin Kif21b binds myosin Va and mediates changes in actin
            dynamics underlying homeostatic synaptic downscaling
  JOURNAL   Cell Rep 42 (7), 112743 (2023)
   PUBMED   37418322
REFERENCE   4  (bases 1 to 9117)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 9117)
  AUTHORS   Asselin,L., Rivera Alvarez,J., Heide,S., Bonnet,C.S., Tilly,P.,
            Vitet,H., Weber,C., Bacino,C.A., Baranano,K., Chassevent,A.,
            Dameron,A., Faivre,L., Hanchard,N.A., Mahida,S., McWalter,K.,
            Mignot,C., Nava,C., Rastetter,A., Streff,H., Thauvin-Robinet,C.,
            Weiss,M.M., Zapata,G., Zwijnenburg,P.J.G., Saudou,F., Depienne,C.,
            Golzio,C., Heron,D. and Godin,J.D.
  TITLE     Mutations in the KIF21B kinesin gene cause neurodevelopmental
            disorders through imbalanced canonical motor activity
  JOURNAL   Nat Commun 11 (1), 2441 (2020)
   PUBMED   32415109
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 9117)
  AUTHORS   Li,Q., Zheng,S., Han,A., Lin,C.H., Stoilov,P., Fu,X.D. and
            Black,D.L.
  TITLE     The splicing regulator PTBP2 controls a program of embryonic
            splicing required for neuronal maturation
  JOURNAL   Elife 3, e01201 (2014)
   PUBMED   24448406
  REMARK    Erratum:[Elife. 2017 Oct 09;6:e31550. doi: 10.7554/eLife.31550..
            PMID: 28990924]
REFERENCE   7  (bases 1 to 9117)
  AUTHORS   Labonte,D., Thies,E., Pechmann,Y., Groffen,A.J., Verhage,M.,
            Smit,A.B., van Kesteren,R.E. and Kneussel,M.
  TITLE     TRIM3 regulates the motility of the kinesin motor protein KIF21B
  JOURNAL   PLoS One 8 (9), e75603 (2013)
   PUBMED   24086586
  REMARK    GeneRIF: TRIM3, also known as BERP, interacts with KIF21B via its
            RBCC domain.
            Publication Status: Online-Only
REFERENCE   8  (bases 1 to 9117)
  AUTHORS   Everett,C.A., Auchincloss,C.A., Kaufman,M.H., Abbott,C.M. and
            West,J.D.
  TITLE     Genetic influences on ovulation of primary oocytes in LT/Sv strain
            mice
  JOURNAL   Reproduction 128 (5), 565-571 (2004)
   PUBMED   15509702
REFERENCE   9  (bases 1 to 9117)
  AUTHORS   Miki,H., Setou,M., Kaneshiro,K. and Hirokawa,N.
  TITLE     All kinesin superfamily protein, KIF, genes in mouse and human
  JOURNAL   Proc Natl Acad Sci U S A 98 (13), 7004-7011 (2001)
   PUBMED   11416179
  REMARK    Review article
REFERENCE   10 (bases 1 to 9117)
  AUTHORS   Marszalek,J.R., Weiner,J.A., Farlow,S.J., Chun,J. and
            Goldstein,L.S.
  TITLE     Novel dendritic kinesin sorting identified by different process
            targeting of two related kinesins: KIF21A and KIF21B
  JOURNAL   J Cell Biol 145 (3), 469-479 (1999)
   PUBMED   10225949
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC124550.4.
            
            On Mar 1, 2018 this sequence version replaced NM_001039472.1.
            
            Transcript Variant: This variant (1) represents the protein-coding
            transcript.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN00849380,
                              SAMN00849383 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            RefSeq Select criteria    :: based on single protein-coding
                                         transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-373               AC124550.4         53947-54319
            374-596             AC124550.4         67156-67378
            597-779             AC124550.4         67687-67869
            780-929             AC124550.4         70055-70204
            930-1064            AC124550.4         70291-70425
            1065-1235           AC124550.4         70764-70934
            1236-1351           AC124550.4         71183-71298
            1352-1547           AC124550.4         71818-72013
            1548-1737           AC124550.4         73688-73877
            1738-1801           AC124550.4         74600-74663
            1802-2020           AC124550.4         74754-74972
            2021-2102           AC124550.4         75315-75396
            2103-2220           AC124550.4         75750-75867
            2221-2412           AC124550.4         76661-76852
            2413-2612           AC124550.4         78654-78853
            2613-2720           AC124550.4         80020-80127
            2721-2789           AC124550.4         80838-80906
            2790-3022           AC124550.4         81801-82033
            3023-3170           AC124550.4         82195-82342
            3171-3365           AC124550.4         82570-82764
            3366-3467           AC124550.4         82861-82962
            3468-3633           AC124550.4         83963-84128
            3634-3685           AC124550.4         84286-84337
            3686-3743           AC124550.4         84521-84578
            3744-3949           AC124550.4         85344-85549
            3950-4027           AC124550.4         85630-85707
            4028-4141           AC124550.4         87575-87688
            4142-4180           AC124550.4         89719-89757
            4181-4317           AC124550.4         91744-91880
            4318-4498           AC124550.4         92546-92726
            4499-4663           AC124550.4         93699-93863
            4664-4781           AC124550.4         94145-94262
            4782-4952           AC124550.4         94716-94886
            4953-5152           AC124550.4         95360-95559
            5153-9117           AC124550.4         96594-100558
FEATURES             Location/Qualifiers
     source          1..9117
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 59.61 cM"
     gene            1..9117
                     /gene="Kif21b"
                     /gene_synonym="2610511N21Rik; mKIAA0449"
                     /note="kinesin family member 21B"
                     /db_xref="GeneID:16565"
                     /db_xref="MGI:MGI:109234"
     exon            1..373
                     /gene="Kif21b"
                     /gene_synonym="2610511N21Rik; mKIAA0449"
                     /inference="alignment:Splign:2.1.0"
     CDS             333..5207
                     /gene="Kif21b"
                     /gene_synonym="2610511N21Rik; mKIAA0449"
                     /note="kinesin-like protein KIF6; N-5 kinesin"
                     /codon_start=1
                     /product="kinesin-like protein KIF21B"
                     /protein_id="NP_001034561.1"
                     /db_xref="CCDS:CCDS15324.1"
                     /db_xref="GeneID:16565"
                     /db_xref="MGI:MGI:109234"
                     /translation="MAGQGDCCVKVAVRIRPQLSKEKIEGCHICTSVTPGEPQVLLGK
                     DKAFTYDFVFDLDTWQEQIYSTCVSKLIEGCFEGYNATVLAYGQTGAGKTYTMGTGFD
                     TVTSEEEQGIIPRAIAHLFRGIDERKRRAQEKGVTGPEFKVSAQFLELYNEEILDLFD
                     STRDPDARHRRSNIKIHEDANGGIYTTGVTSRLINSQEELIQCLKQGALSRTTASTQM
                     NVQSSRSHAIFTIHLCQMRVCAQPDLVNETVTGLPDGAAPTGTEYETLTAKFHFVDLA
                     GSERLKRTGATGERAKEGISINCGLLALGNVISALGDQSKKVVHVPYRDSKLTRLLQD
                     SLGGNSQTIMIACVSPSDRDFMETLNTLKYANRARNIKNKVVVNQDKTSQQISALRAE
                     IARLQMELMEYKAGKRVIGEDGTEGYSDLFRENAMLQKENGALRLRVKAMQEAIDAIN
                     NRVTQLMSQEANLLLAKAGDGNEAIGALIQNYIREIEELRTKLLESEAMNESLRRSLS
                     RASARNPYSLGASPAGPAFGGSPATSMEDASEVIRKAKQDLERLKKKEVRQRRKSPEK
                     EAFKKRAKLQAENSEETDENEAEEEEEERDESGCEEEEGREDEDEDSGSEESLVDSDS
                     DPEEKEVNFQADLADLTCEIEIKQKLIDELENSQRRLQTLKHQYEEKLILLQNKIRDT
                     QLERDRVLQNLSTMECYTEEKANKIKADYEKRLREMNRDLQKLQAAQKEHARLLKNQS
                     RYERELKKLQAEVAEMKKAKVALMKQMREEQQRRRLVETKRNREIAQLKKEQRRQEFQ
                     IRALESQKRQQEIVLRRKTQEVSALRRLAKPMSERVAGRVGLKPPNMDSGAEVSASTT
                     SSEAESGARSVSSIVRQWNRKIDHFLGDRPTATVNGGRPARKKFQKKGASQSFSKAAR
                     LKWQSLERRIIDIVMQRMTIVNLEADMERLIKKREELFLLQEALRRKREHLQAESPEE
                     EKGLQELAEEIEVLAANIDYINDSITDCQATIVQLEETKEELDSTDTSVVISSCSLAE
                     ARLLLDNFLKASIDKGLQVAQKEAQIRLLEGRLRQTDMTGSSQNHLLLDALREKAEAH
                     PELQALIYNVQHENGYASTDEEVSEFSEGSFSQSFTMKGSTSHDDFKFKGEPKLSAQM
                     KAVSAECLGPPLDSSTKNITKSLASLVEIKEDGVGFSIRDPYYRDKVSRTVSLPTRGS
                     TFPRQSRGATDTSPLTRRKSYDRGQPIRSTDMGFTPPSSPPTRPRNDRNVFSRLTSNQ
                     SQGSALDKSDDSDSSLSEVLRGIITPIGGAKGARTAPLQCISMAEGHTKPILCLDATD
                     ELLFTGSKDRSCKMWNLVTGQEIAALKGHPNNVVSIKYCSHSGLVFSVSSSYIKVWDI
                     RDSAKCIRTLTSSGQVISGDACIATSTRAITSAQGEHQINQMALSPSGSMLYVASGNA
                     VRIWELNRFQPIGKLTGHIGPVMCLTVTQTSNQHDLVVTGSKDHYVKMFQLGDCVTGT
                     IGPTHNFEPPHYDGIECLAIQGDILFSGSRDNGIKKWDLDQQELIQQIPNAHKDWVCA
                     LAFVPGRPMLLSACRAGFIKVWNVDNFTPIGEIKGHDSPINAICTNSKHIFTASSDLT
                     VKFWSIRRLPAAHP"
     exon            374..596
                     /gene="Kif21b"
                     /gene_synonym="2610511N21Rik; mKIAA0449"
                     /inference="alignment:Splign:2.1.0"
     exon            597..779
                     /gene="Kif21b"
                     /gene_synonym="2610511N21Rik; mKIAA0449"
                     /inference="alignment:Splign:2.1.0"
     exon            780..929
                     /gene="Kif21b"
                     /gene_synonym="2610511N21Rik; mKIAA0449"
                     /inference="alignment:Splign:2.1.0"
     exon            930..1064
                     /gene="Kif21b"
                     /gene_synonym="2610511N21Rik; mKIAA0449"
                     /inference="alignment:Splign:2.1.0"
     exon            1065..1235
                     /gene="Kif21b"
                     /gene_synonym="2610511N21Rik; mKIAA0449"
                     /inference="alignment:Splign:2.1.0"
     exon            1236..1351
                     /gene="Kif21b"
                     /gene_synonym="2610511N21Rik; mKIAA0449"
                     /inference="alignment:Splign:2.1.0"
     exon            1352..1547
                     /gene="Kif21b"
                     /gene_synonym="2610511N21Rik; mKIAA0449"
                     /inference="alignment:Splign:2.1.0"
     exon            1548..1737
                     /gene="Kif21b"
                     /gene_synonym="2610511N21Rik; mKIAA0449"
                     /inference="alignment:Splign:2.1.0"
     exon            1738..1801
                     /gene="Kif21b"
                     /gene_synonym="2610511N21Rik; mKIAA0449"
                     /inference="alignment:Splign:2.1.0"
     exon            1802..2020
                     /gene="Kif21b"
                     /gene_synonym="2610511N21Rik; mKIAA0449"
                     /inference="alignment:Splign:2.1.0"
     exon            2021..2102
                     /gene="Kif21b"
                     /gene_synonym="2610511N21Rik; mKIAA0449"
                     /inference="alignment:Splign:2.1.0"
     exon            2103..2220
                     /gene="Kif21b"
                     /gene_synonym="2610511N21Rik; mKIAA0449"
                     /inference="alignment:Splign:2.1.0"
     exon            2221..2412
                     /gene="Kif21b"
                     /gene_synonym="2610511N21Rik; mKIAA0449"
                     /inference="alignment:Splign:2.1.0"
     exon            2413..2612
                     /gene="Kif21b"
                     /gene_synonym="2610511N21Rik; mKIAA0449"
                     /inference="alignment:Splign:2.1.0"
     exon            2613..2720
                     /gene="Kif21b"
                     /gene_synonym="2610511N21Rik; mKIAA0449"
                     /inference="alignment:Splign:2.1.0"
     exon            2721..2789
                     /gene="Kif21b"
                     /gene_synonym="2610511N21Rik; mKIAA0449"
                     /inference="alignment:Splign:2.1.0"
     exon            2790..3022
                     /gene="Kif21b"
                     /gene_synonym="2610511N21Rik; mKIAA0449"
                     /inference="alignment:Splign:2.1.0"
     exon            3023..3170
                     /gene="Kif21b"
                     /gene_synonym="2610511N21Rik; mKIAA0449"
                     /inference="alignment:Splign:2.1.0"
     exon            3171..3365
                     /gene="Kif21b"
                     /gene_synonym="2610511N21Rik; mKIAA0449"
                     /inference="alignment:Splign:2.1.0"
     exon            3366..3467
                     /gene="Kif21b"
                     /gene_synonym="2610511N21Rik; mKIAA0449"
                     /inference="alignment:Splign:2.1.0"
     exon            3468..3633
                     /gene="Kif21b"
                     /gene_synonym="2610511N21Rik; mKIAA0449"
                     /inference="alignment:Splign:2.1.0"
     exon            3634..3685
                     /gene="Kif21b"
                     /gene_synonym="2610511N21Rik; mKIAA0449"
                     /inference="alignment:Splign:2.1.0"
     exon            3686..3743
                     /gene="Kif21b"
                     /gene_synonym="2610511N21Rik; mKIAA0449"
                     /inference="alignment:Splign:2.1.0"
     exon            3744..3949
                     /gene="Kif21b"
                     /gene_synonym="2610511N21Rik; mKIAA0449"
                     /inference="alignment:Splign:2.1.0"
     exon            3950..4027
                     /gene="Kif21b"
                     /gene_synonym="2610511N21Rik; mKIAA0449"
                     /inference="alignment:Splign:2.1.0"
     exon            4028..4141
                     /gene="Kif21b"
                     /gene_synonym="2610511N21Rik; mKIAA0449"
                     /inference="alignment:Splign:2.1.0"
     exon            4142..4180
                     /gene="Kif21b"
                     /gene_synonym="2610511N21Rik; mKIAA0449"
                     /inference="alignment:Splign:2.1.0"
     exon            4181..4317
                     /gene="Kif21b"
                     /gene_synonym="2610511N21Rik; mKIAA0449"
                     /inference="alignment:Splign:2.1.0"
     exon            4318..4498
                     /gene="Kif21b"
                     /gene_synonym="2610511N21Rik; mKIAA0449"
                     /inference="alignment:Splign:2.1.0"
     exon            4499..4663
                     /gene="Kif21b"
                     /gene_synonym="2610511N21Rik; mKIAA0449"
                     /inference="alignment:Splign:2.1.0"
     exon            4664..4781
                     /gene="Kif21b"
                     /gene_synonym="2610511N21Rik; mKIAA0449"
                     /inference="alignment:Splign:2.1.0"
     exon            4782..4952
                     /gene="Kif21b"
                     /gene_synonym="2610511N21Rik; mKIAA0449"
                     /inference="alignment:Splign:2.1.0"
     exon            4953..5152
                     /gene="Kif21b"
                     /gene_synonym="2610511N21Rik; mKIAA0449"
                     /inference="alignment:Splign:2.1.0"
     exon            5153..9117
                     /gene="Kif21b"
                     /gene_synonym="2610511N21Rik; mKIAA0449"
                     /inference="alignment:Splign:2.1.0"
     regulatory      9097..9102
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Kif21b"
                     /gene_synonym="2610511N21Rik; mKIAA0449"
                     /note="hexamer: AATAAA"
     polyA_site      9117
                     /gene="Kif21b"
                     /gene_synonym="2610511N21Rik; mKIAA0449"
                     /note="major polyA site"
ORIGIN      
        1 gttcgcgctg cggcgggagg tggcggtccg ggtgggaggt gtgtgcgcgc gcgtgtgccg
       61 cgctgtaggg agctgcgggt ctcactgccc gctgtcaacg agctcagcac ctccgcgcga
      121 tggctggagg agacgcatgg gaccagcccc gtggggccgg ccgcggctga gcccctctgc
      181 cgcctcctgc gagcatgtca cctccagcct acgaggtcgc tttcgctagc agggtccctg
      241 cctccgcctt ctgcagccgc agccgctgcc tggagcagtg gcccccggac ccccgcccct
      301 gatccgcgcc cagaccctgg tgccggagga ccatggctgg ccagggcgac tgctgcgtca
      361 aagtggccgt caggatccgg ccccagctgt caaaggagaa gattgaaggc tgtcacatct
      421 gtacctccgt taccccggga gagccccagg tcctgctggg gaaggacaag gccttcacct
      481 atgactttgt ctttgacctg gacacctggc aggagcaaat ctattcgacc tgtgtgagca
      541 aactcatcga aggctgcttt gagggctata atgccacagt cctagcctat ggacagacag
      601 gggctgggaa gacatatact atgggcaccg gctttgacac agtgacatca gaagaggagc
      661 agggcatcat cccaagggcc attgcacatc tcttcagggg catcgacgaa cgcaagcggc
      721 gggcacaaga gaagggtgtg actgggcctg agttcaaagt cagtgctcaa ttcctggagc
      781 tctacaatga agagatcctt gacctatttg acagcacccg tgaccccgat gcccgacacc
      841 gcaggtccaa catcaagatc cacgaggatg ccaacggtgg catctacacc acaggtgtca
      901 cttctcgcct gatcaactcc caggaggagc tgatccagtg cctgaagcag ggcgccctgt
      961 cacgtaccac agccagcacc cagatgaatg tacagagctc ccgatcccat gccatcttca
     1021 ccatccacct gtgccagatg cgcgtgtgtg cccagcctga cctggtgaat gagaccgtga
     1081 ctgggcttcc agatggagcc gcccccacag gcactgagta cgagactctc actgctaagt
     1141 ttcacttcgt ggacttggct ggctcagagc ggctgaagcg gacaggggcc accggcgaac
     1201 gggccaaaga gggcatctcc atcaactgtg gtctgctggc cttgggcaat gtgatcagcg
     1261 ccttggggga ccagagcaag aaggtcgtgc acgtgcctta cagggactcc aagctcactc
     1321 ggctgctcca ggactctctt ggaggcaaca gccagaccat catgatcgcc tgtgtgagcc
     1381 cctcggatcg ggacttcatg gagacactta acactctcaa atatgccaac cgggcccgca
     1441 acatcaaaaa caaagtggtg gtgaaccagg acaagaccag ccagcagatc agcgcgctgc
     1501 gggctgagat cgcacgcctg cagatggagt tgatggagta caaagcgggc aagcgagtga
     1561 ttggggagga cggtacagag ggctacagtg acctgttccg agagaacgcc atgctgcaga
     1621 aggagaatgg ggcgctgcgg ctccgagtga aggccatgca ggaagccatt gatgccatca
     1681 acaaccgggt cacacaactc atgagccagg aggccaacct gcttctggcc aaggctggtg
     1741 atggcaatga ggccattggt gctctgatcc agaactacat ccgggagatc gaggagctgc
     1801 gaacaaagct cctggagagt gaggctatga atgagtccct ccgcagaagc ctctcccggg
     1861 cttccgctcg gaatccctac tccctgggag catctccagc aggtccagcc tttgggggca
     1921 gccccgccac ctccatggaa gatgcttctg aagtgatccg caaggctaag caagacctgg
     1981 agcggctgaa aaagaaggag gtcaggcagc ggaggaagag cccagagaaa gaagcgttca
     2041 agaagagggc aaaactccag gcagaaaaca gtgaggagac agacgagaac gaggctgagg
     2101 aggaggagga agagcgagat gaaagtggct gtgaggagga ggaaggtcgt gaggatgagg
     2161 atgaagactc gggcagtgaa gagagcctgg tagactcaga ctccgaccct gaagaaaagg
     2221 aagtgaactt ccaggccgac ctggcagacc tgacgtgtga gatcgagatc aagcagaagc
     2281 tgatcgacga gctggagaac agccagcggc ggctgcagac gctcaagcac cagtacgagg
     2341 agaagctaat tctgctgcag aacaagatcc gggatacgca gctggagcgt gaccgcgtgc
     2401 tgcagaacct cagcactatg gagtgctaca cggaagagaa ggccaacaag ataaaggcag
     2461 attatgagaa gagactgcgg gagatgaacc gggacctgca gaagctacag gctgctcaaa
     2521 aagaacatgc caggctactc aagaaccagt ctcgctatga aagggagctg aagaagctac
     2581 aagcggaggt agctgagatg aagaaggcca aggtagccct catgaagcaa atgcgtgagg
     2641 agcagcagcg gcggcgactg gtggagacca agaggaaccg ggagattgct cagctcaaga
     2701 aggagcaacg gaggcaggag tttcagatac gagccctgga atctcagaag cgccagcagg
     2761 aaatagttct gaggaggaaa acccaggagg tttctgcact gaggcgcctg gcaaagccca
     2821 tgtctgagcg agtggctggg cgtgtaggat tgaagccccc caatatggat tctggggctg
     2881 aggtgtctgc cagcaccacc tcgtctgagg ctgagtcggg agcccgctcc gtctccagca
     2941 tagtgcgtca gtggaaccgg aagatcgacc acttcctggg agaccgcccc accgccactg
     3001 tcaatggcgg ccgcccagcc aggaaaaagt tccaaaagaa gggagccagc caaagcttca
     3061 gtaaggctgc gagactcaaa tggcagtccc tggaacggag gatcattgac attgtcatgc
     3121 agagaatgac catcgtcaac ctggaggctg atatggagcg tctcataaag aaaagggagg
     3181 agctcttcct cctgcaggag gcgctgcgga ggaagcggga gcacctgcag gctgagagcc
     3241 cagaggagga gaaggggctc caggagctgg ctgaggagat cgaagtgttg gcagccaata
     3301 ttgactacat caacgacagc atcactgact gccaagccac catcgtgcag ctggaggaaa
     3361 ccaaggagga gctggactca acagacacgt cagtggtcat tagctcctgc tctctggctg
     3421 aagcccgcct cctgctagac aacttcctca aggcgtccat tgacaaggga cttcaagtag
     3481 cacagaagga agcccagatc cggctgctag aaggacgcct tagacagaca gacatgacag
     3541 gctcttccca gaaccacctg ctcctagacg ctttgcgtga gaaggccgag gcacaccccg
     3601 agctgcaggc cctcatctac aatgtgcagc atgagaatgg ctatgcaagc acagatgagg
     3661 aagtttctga gttctctgag gggagctttt cccagtcatt taccatgaaa ggctccacca
     3721 gccacgatga cttcaagttc aagggtgagc ccaagctatc cgcacagatg aaggccgtgt
     3781 ctgcggagtg cctaggaccc ccattggaca gctctaccaa gaacatcacc aagtccctgg
     3841 cctccctcgt tgagatcaaa gaggatgggg tgggcttctc tatccgggac ccctactacc
     3901 gggacaaggt ctcacgcacc gtcagcctgc ccacccgggg cagcactttc cctcggcaat
     3961 ctcgaggtgc cacggacacg tctcctctta cccgaaggaa gtcttatgac cggggacagc
     4021 ccatcagatc cacagacatg ggattcacac ctccctcatc acctcccact cggccccgca
     4081 acgaccgcaa cgtcttctct cgtctcacca gcaatcagag ccagggctca gcactggaca
     4141 agtctgatga cagcgactcc tctttgtcgg aggtcctgag gggcatcatc acccccattg
     4201 gcggagctaa gggagcgcgg acggccccgc tgcagtgcat ctccatggcc gagggtcaca
     4261 ccaagcccat cctctgcctg gatgccaccg atgagctgct tttcacggga tccaaagacc
     4321 gtagctgcaa gatgtggaac ctggtgacag ggcaggagat tgcagctctc aagggtcacc
     4381 ccaacaacgt ggtttctatc aaatactgca gccactcggg gctggtgttc tctgtgtcca
     4441 gctcctacat caaggtgtgg gatatccggg actcagccaa gtgcattcgg acactcacgt
     4501 cctcaggcca ggtgatctca ggagatgcgt gcatagccac atccacccgc gccatcacca
     4561 gtgcccaggg ggaacatcag atcaaccaga tggccctcag cccctcaggc tccatgctat
     4621 acgttgcctc tggcaatgct gtccgcatct gggagctcaa caggttccag cccattggca
     4681 aactgactgg ccacattggc ccagtgatgt gcctaacagt cacccagact tcaaaccagc
     4741 atgacctcgt ggtgacgggc tccaaggacc actatgtgaa gatgttccag ctgggcgact
     4801 gtgtgacggg caccattggc ccaacccaca actttgagcc ccctcactat gatggtattg
     4861 aatgcctggc tatccaagga gacatactct tcagtggctc cagagacaat ggcatcaaga
     4921 agtgggacct ggaccagcag gagctcatcc agcaaatccc caacgctcac aaggactggg
     4981 tgtgcgccct ggcctttgta cccggccggc ccatgctgct gagcgcctgc cgggccggct
     5041 tcatcaaggt ctggaatgtg gacaacttca cacccattgg tgagatcaag ggccacgaca
     5101 gccccatcaa tgccatctgc accaacagca agcacatctt cacggcctcc agtgacctga
     5161 cagtgaagtt ctggagcata cggcggctac cagcagccca cccttgaagt taggactaaa
     5221 ggtggctaga ccgtcagatc agacccagca gcctacccag cacggaaagg aagctgtggc
     5281 ccgaccttac cggaacagcc aagttcaccg gagtacagag ggtgtggctc ttctctcgct
     5341 ctgcttcctc caccacccct tctgtccctc ccctgcctcc taagaaagac gaggtggagg
     5401 agggacacaa gctgtgaagc caaagggcac gattccccaa gctgctgctc cacctgttcc
     5461 caagccttcc tctcaactgg ccacattgtc tcctgctgag ccagccctgc ccctccccca
     5521 ggccctcagc ctcggttgag accgagggag aagcagggag aagcccccat ctatcttcca
     5581 gtgagctagc ctcctctgtg tctcctagcc ccacctccgg agccgcttca cctgcctctg
     5641 agcccaccaa ggtagttctc aggtaaccat ggaaaccaga tgtaagcagc tgagtcctgc
     5701 cgctcaccca cagccaatcc cagtggggcc ccggcccagt ctttccttga ggttctcttc
     5761 tgctggggcc tcagtggagc tgtttaaaca gttcctttgg ggggaaggtc agcggcactg
     5821 cagtcattta atatattgat ttttattttt gtgttctgct gtttgcctcc tggaaactga
     5881 cttgaagttt cttcccattc ttccctcccc tcctggcacg gaggtggggt ggggtggggt
     5941 gggggtgggg gccttccctc tgcttgctct gcagatgagg ggatagcctt ctctatcctt
     6001 tgcagctctg acaattgccc cggacctgcc catgccggca taccttctag gatagaccag
     6061 gtctctaggc cgcctaatgc cgcagtgcct ttctccatcc tgaggcctga tatcatgccg
     6121 ggcagcctta tactagccat gcccgcagcc cacttgtgtc ttctactcct gggcctggtg
     6181 cccacagccc ctgaaggtca gagcattcac cccaacggcc cagtaccagg gagcttggtg
     6241 gactgcccac taggtaggct ttgagtagta agggtaccag gtcctttgcc taacccccca
     6301 gccagttatg tttccacccc caaggggcta gggaacatct tcagcttctt ttcctttagt
     6361 tgttccagaa acagccttaa aaccagcctg ggacaaaggc cctccctttt caattagcgt
     6421 gaggaggcag tgactccttg cttctcccct tggtgctgtg gactcagctg ctgggatgag
     6481 gtgaagtcag tgtctagcgc cccctactgg aacaactctg aatttataga actgggccat
     6541 gagaggggcc agctccgttc ctcccccggc ttcccctgcc cttaaactgg tccacactta
     6601 ctctattgct tcactggtct tatgcatcct ggtctcattc cgggatccat gagcctcagc
     6661 cccattcaga ggccgtggtg acttgtggag agctagcata gcgccactgt acttagctct
     6721 tctccctcta gggcgagtac gttggtgcct gtccatgagg ccctaggatg ggagagttag
     6781 gaactgataa ggtcagaccc tctctgaacc ttcccagagc tgtgtctgaa gctgaaacta
     6841 agaagattgt cccgcttatt ggtggctcca gccagacacg gtgttaagtc tgggtaagtg
     6901 gatatttaga acggagcacc ggaaaagcag atcacctgga acctggaccg tctgtctgca
     6961 aagaccagaa atcctccttc ccctgctcat cctgggagtg ttaaggaaca tccttagcac
     7021 tcagaagtga ccacatcttc tccttcaccc atctccacct aaatggaaag cccggacctt
     7081 acaccctgta agaaaaccca gaacccgtct gcatggctgt ttacaaacta cagaaacacg
     7141 tgagactttg tcccgacccc tcaggctggg ccgccccagc ccggggtgcc tgtactgtat
     7201 gtatagctgc aaggccagtt cttgcacaaa gtgtgtgtgg tcttacagcc cccgcgagag
     7261 gtgctcaccg gcattacccc ttctgccatt tctgatgggt cactacctca tggcggggct
     7321 gctatgctgt cccagcgagt gtcattgact aaacttgaaa tcggagctct gagctcatcg
     7381 tcctgagcca ttctgagctg tgttctggga acgttggagt ccctgctcac ccaccctttc
     7441 ggggatgtcc aaggtacata gtcaggggca ggaccccagc tccactcatt gcacaagcat
     7501 ccttcttgtc ggaagcacaa actggttgta atttgagcac aatagcaggt ctctgggtag
     7561 acagtatgag caaacttggc accaggagat ctttcccaga tgggcttcgt cttaggttag
     7621 accagggctg cccgtgtctg tgaggttaga ccaaggctgc ccatgtcttt ggctgacgca
     7681 ctatgtacac tgggaactat taatttactc cttgtgcccc tcctaggact tgaggcccag
     7741 gccacatctg tatcctgtgg gggtcctctc tagacctgca caccccaagc ctttaacaac
     7801 cagagtatag ctggtacctg accctactga gcctgaagag cctggaccca gactcccatc
     7861 tcttgagcta accccgacat ccttgcttcc gatattgatt agcttccatg gaaagtgtct
     7921 actgtcccca ctctcttagg tcttttctgt gcacagtcct gggccaggac ccatcccagt
     7981 attaaccagt tcagtgtttg gtcttgttgg tgagacttgg tccgacagca gccaactcaa
     8041 tgcacatgct gcctggagca gcctttagag actgcagagg aaagagagag aactcgaaga
     8101 atgagaggct gacccagcgc agcccttgat gtggtcagag tgccaccaca gctacttgaa
     8161 aagggacagc tatggacctg ggagtagcct cccaccgttg ctccagctgc aggcctggaa
     8221 tggtcttagg ctgtgtggct tgggcaaagg gcagcttaaa gcacaaacaa ggagaagatg
     8281 ctgtcttgct gaaggattct tctgctagcc attgtggtgg tggcgccagc aggaagctgc
     8341 tgagaaggca ggacattaca tctctgccct gccctctccc agttcctgga ggcctccctt
     8401 ggagtctggg ctgggtgcag caggcacacc cccttggctg tgcctggtat gtttgtgtgg
     8461 gcaggacttg ccctgcagga gcggtgaatt ccttcccacc atgtagccca aacctgccac
     8521 atctatccct ttgtcctttc aaataaaaaa ctgcttactg ctgctctctt tgctgagcac
     8581 agtggccagt tccccaacag accttcttga gcccagccct ttcacctcct gactcccagg
     8641 tcttcactgc tccttgtgag caagagaatc tacagggaga gttcggtttc tttgacatca
     8701 ttgttctgtc cccggtgccc cccacccact tcatctccag cacccagctg gcctccctca
     8761 tccctgtccc ttccaccttc acttctgtgt cctaaaggct ttgtcagaaa gtgggaagtc
     8821 ggtactgccg agagtcagaa aagacctctg atgtcttggt gccctgccct gccctggcct
     8881 gccctgccct gtcaccagct cttatgatgg ttgtccctac ccagactgca gggtctcgtt
     8941 tggctcatgc actctcctgt gacgtagtag cacaaggtgt gtatatgttt tgtacctctg
     9001 ctgacaactg tacatagtgt atgaaagtta tttaagcctc atgctgtaca tttctgttct
     9061 ggaaatcgga tgtgtgtgtt ctaagagctt gtcataaata aaaccattgt ccacaga
//
